Induction and Maintenance of IL-4 Expression Are Regulated Differently by the 39 Enhancer in CD4 T Cells

[1]  B. Kee,et al.  SAP protein-dependent natural killer T-like cells regulate the development of CD8(+) T cells with innate lymphocyte characteristics. , 2010, Immunity.

[2]  S. Jameson,et al.  T cells expressing the transcription factor PLZF regulate the development of memory-like CD8+ T cells , 2010, Nature Immunology.

[3]  K. Nichols,et al.  PLZF Induces the Spontaneous Acquisition of Memory/Effector Functions in T Cells Independently of NKT Cell-Related Signals , 2010, The Journal of Immunology.

[4]  Byung Hyun Kang,et al.  Generation of PLZF+ CD4+ T cells via MHC class II–dependent thymocyte–thymocyte interaction is a physiological process in humans , 2010, The Journal of experimental medicine.

[5]  P. Pandolfi,et al.  The BTB–zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions , 2008, Nature Immunology.

[6]  S. Rietdijk,et al.  The SLAM-associated protein signaling pathway is required for development of CD4+ T cells selected by homotypic thymocyte interaction. , 2007, Immunity.

[7]  M. Kaplan,et al.  Thymic selection pathway regulates the effector function of CD4 T cells , 2007, The Journal of experimental medicine.

[8]  L. Harrington,et al.  Expanding the effector CD4 T-cell repertoire: the Th17 lineage. , 2006, Current opinion in immunology.

[9]  K. Murphy,et al.  Th17: an effector CD4 T cell lineage with regulatory T cell ties. , 2006, Immunity.

[10]  M. Kubo,et al.  The interleukin-4 enhancer CNS-2 is regulated by Notch signals and controls initial expression in NKT cells and memory-type CD4 T cells. , 2006, Immunity.

[11]  T. Mcclanahan,et al.  IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. , 2006, The Journal of clinical investigation.

[12]  Y. Iwakura,et al.  The IL-23/IL-17 axis in inflammation. , 2006, The Journal of clinical investigation.

[13]  Ying Wang,et al.  A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17 , 2005, Nature Immunology.

[14]  R. D. Hatton,et al.  Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages , 2005, Nature Immunology.

[15]  T. Gourley,et al.  An alternate pathway for CD4 T cell development: thymocyte-expressed MHC class II selects a distinct T cell population. , 2005, Immunity.

[16]  E. Choi,et al.  Thymocyte-thymocyte interaction for efficient positive selection and maturation of CD4 T cells. , 2005, Immunity.

[17]  A. Fischer,et al.  Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product , 2005, The Journal of experimental medicine.

[18]  S. Tangye,et al.  Regulation of NKT cell development by SAP, the protein defective in XLP , 2005, Nature Medicine.

[19]  T. Mcclanahan,et al.  IL-23 drives a pathogenic T cell population that induces autoimmune inflammation , 2005, The Journal of experimental medicine.

[20]  K. Oldham,et al.  Thymic transplantation for complete DiGeorge syndrome: medical and surgical considerations. , 2004, Journal of pediatric surgery.

[21]  J. Li,et al.  Postnatal thymus transplantation with immunosuppression as treatment for DiGeorge syndrome. , 2004, Blood.

[22]  Y. Sung,et al.  T cell expression of CIITA represses Th1 immunity. , 2004, International immunology.

[23]  Richard A Flavell,et al.  Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells , 2004, Cell.

[24]  Markus G. Manz,et al.  Development of a Human Adaptive Immune System in Cord Blood Cell-Transplanted Mice , 2004, Science.

[25]  W. Paul,et al.  Probabilistic regulation of IL-4 production in Th2 cells: accessibility at the Il4 locus. , 2004, Immunity.

[26]  E. Rubin,et al.  Basal Chromatin Modification at the IL-4 Gene in Helper T Cells1 , 2003, The Journal of Immunology.

[27]  B. Haynes,et al.  Thymus transplantation in complete DiGeorge syndrome: immunologic and safety evaluations in 12 patients. , 2003, Blood.

[28]  Mamoru Ito,et al.  Complete reconstitution of human lymphocytes from cord blood CD34+ cells using the NOD/SCID/gammacnull mice model. , 2003, Blood.

[29]  R. Kastelein,et al.  Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain , 2003, Nature.

[30]  T. Nomura,et al.  The in vivo development of human T cells from CD34(+) cells in the murine thymic environment. , 2002, International immunology.

[31]  Y. Ueyama,et al.  Functional Human T Lymphocyte Development from Cord Blood CD34+ Cells in Nonobese Diabetic/Shi-scid, IL-2 Receptor γ Null Mice1 , 2002, The Journal of Immunology.

[32]  R. Locksley,et al.  Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter. , 2001, Immunity.

[33]  Edward M. Rubin,et al.  Deletion of a coordinate regulator of type 2 cytokine expression in mice , 2001, Nature Immunology.

[34]  P. J. van den Elsen,et al.  T cell immune reconstitution after allogeneic bone marrow transplantation in bare lymphocyte syndrome. , 2000, Human immunology.

[35]  A. Rao,et al.  Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo. , 2000, Immunity.

[36]  W. Miller,et al.  Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons. , 2000, Science.

[37]  M. Kaplan,et al.  Stat6-dependent and -independent pathways for IL-4 production. , 1999, Journal of immunology.

[38]  B. Osborne,et al.  Notch and the immune system. , 1999, Immunity.

[39]  Suneet Agarwal,et al.  Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation. , 1998, Immunity.

[40]  K. Arai,et al.  Th2-specific DNase I-hypersensitive sites in the murine IL-13 and IL-4 intergenic region. , 1998, International immunology.

[41]  Raphael Kopan,et al.  Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain , 1998, Nature.

[42]  Tasuku Honjo The shortest path from the surface to the nucleus: RBP‐Jκ/Su(H) transcription factor , 1996, Genes to cells : devoted to molecular & cellular mechanisms.

[43]  A. Bendelac Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes , 1995, The Journal of experimental medicine.

[44]  A. Fischer,et al.  Bone marrow transplantation in major histocompatibility complex class II deficiency: a single-center study of 19 patients. , 1995, Blood.

[45]  R. Coffman,et al.  Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. , 1986, Journal of immunology.

[46]  R. Kastelein,et al.  Understanding the IL-23-IL-17 immune pathway. , 2006, Trends in immunology.

[47]  M. Kaplan,et al.  Constitutive expression of CIITA directs CD4 T cells to produce Th2 cytokines in the thymus. , 2005, Cellular immunology.

[48]  M. Kubo,et al.  Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling. , 2004, Immunity.

[49]  R. Locksley,et al.  Mouse V alpha 14i natural killer T cells are resistant to cytokine polarization in vivo. , 2003, Proceedings of the National Academy of Sciences of the United States of America.