The Society for Clinical Trials supports United States legislation mandating trials registration

The official position of the Society for Clinical Trials is to support legislation in the United States and internationally that mandates registration of all controlled clinicals trials at or before enrollment of the first participant. The major trial sponsor would be responsible for ensuring contribution of trial information. The mechanism for registering trials would be through research ethics review boards, and registration would be required for ethics approval and before trial initiation. Standardized data and a unique identification number would be available for each registered trial.

[1]  T. Pang,et al.  Registering clinical trials: an essential role for WHO , 2004, The Lancet.

[2]  Peter Fonagy,et al.  Selective serotonin reuptake inhibitors in childhood depression: systematic review of published versus unpublished data , 2004, The Lancet.

[3]  I. Leviton,et al.  Registering clinical trials. , 2003, JAMA.

[4]  A. Tonks,et al.  A clinical trials register for Europe , 2002, BMJ : British Medical Journal.

[5]  E. Manheimer,et al.  Survey of public information about ongoing clinical trials funded by industry: evaluation of completeness and accessibility , 2002, BMJ : British Medical Journal.

[6]  Steve McDonald,et al.  Development of the Cochrane Collaboration’s Central Register of Controlled Clinical Trials , 2002, Evaluation & the health professions.

[7]  Douglas G. Altman,et al.  Systematic Reviews in Health Care: Meta-Analysis in Context: Second Edition , 2008 .

[8]  C. Vale,et al.  The International Standard Randomised Controlled Trial Number (ISRCTN): what does it mean for reviewers? , 2001 .

[9]  A. McCray.  Better Access to Information about Clinical Trials , 2000, Annals of Internal Medicine.

[10]  J. Blunt,et al.  Research ethics committees must ensure registration of research and accessibility of results , 1998, BMJ.

[11]  K. Dickersin.  How important is publication bias? A synthesis of available data. , 1997, AIDS education and prevention : official publication of the International Society for AIDS Education.

[12]  A. Skene,et al.  The effect of lorcainide on arrhythmias and survival in patients with acute myocardial infarction: an example of publication bias. , 1993, International journal of cardiology.

[13]  K. Dickersin,et al.  Regulatory process effects clinical trial registration in Spain. , 1992, Controlled clinical trials.

[14]  Kay Dickersin,et al.  Keeping posted Why register clinical trials?-Revisited , 1992 .

[15]  K. Dickersin,et al.  Why register clinical trials?--Revisited. , 1992, Controlled clinical trials.

[16]  I Chalmers,et al.  Underreporting research is scientific misconduct. , 1990, JAMA.

[17]  I. Chalmers,et al.  Retrospective and prospective identification of unpublished controlled trials: lessons from a survey of obstetricians and pediatricians. , 1989, Pediatrics.

[18]  K. Dickersin.  Report from the panel on the Case for Registers of Clinical Trials at the Eighth Annual Meeting of the Society for Clinical Trials. , 1988, Controlled clinical trials.

[19]  C. Meinert,et al.  Toward prospective registration of clinical trials. , 1988, IRB.

[20]  K. Dickersin,et al.  Publication bias and clinical trials. , 1987, Controlled clinical trials.

[21]  L Mutch,et al.  The Oxford Database of Perinatal Trials: developing a register of published reports of controlled trials. , 1986, Controlled clinical trials.

[22]  R. Simes.  Publication bias: the case for an international registry of clinical trials. , 1986, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[23]  C. Furberg.  Effect of antiarrhythmic drugs on mortality after myocardial infarction. , 1983, The American journal of cardiology.

[24]  Chalmers Tc.  Randomize the first patient , 1977 .