Reply to Philip et al.: Aerosol Transmission of SARS-CoV-2: Inhalation as well as Exhalation Matters for COVID-19

1. Echternach M, Gantner S, Peters G, Westphalen C, Benthaus T, Jakubaß B, et al. Impulse dispersion of aerosols during singing and speaking: a potential COVID-19 transmission pathway. Am J Respir Crit Care Med 2020;202:1584–1587. 2. Jones NR, Qureshi ZU, Temple RJ, Larwood JPJ, Greenhalgh T, Bourouiba L. Two metres or one: what is the evidence for physical distancing in covid-19? BMJ 2020;370:m3223. 3. Philip KEJ, Lewis A, Buttery SC, McCabe C, Fancourt D, Orton C, et al. The physiological demands of Singing for Lung Health compared to treadmill walking [preprint]. medRxiv;2020 [accessed 2020 Dec 15]. Available from: https://www.medrxiv.org/content/10.1101/2020. 12.08.20245746v1. 4. Russell BA, Cerny FJ, Stathopoulos ET. Effects of varied vocal intensity on ventilation and energy expenditure in women and men. J Speech Lang Hear Res 1998;41:239–248. 5. Hoit JD, Lohmeier HL. Influence of continuous speaking on ventilation. J Speech Lang Hear Res 2000;43:1240–1251. 6. Guallar MP, Meiriño R, Donat-Vargas C, Corral O, Jouvé N, Soriano V. Inoculum at the time of SARS-CoV-2 exposure and risk of disease severity. Int J Infect Dis 2020;97:290–292. 7. Chu H, Chan JF, Wang Y, Yuen TT, Chai Y, Hou Y, et al. Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19. Clin Infect Dis 2020;71:1400– 1409.

[1]  M. Polkey,et al.  Physiological demands of singing for lung health compared with treadmill walking , 2020, BMJ Open Respiratory Research.

[2]  K. Prather Mario J. Molina (1943–2020) , 2020, Science.

[3]  S. Kniesburges,et al.  Impulse Dispersion of Aerosols during Singing and Speaking: A Potential COVID-19 Transmission Pathway , 2020, American journal of respiratory and critical care medicine.

[4]  R. Schooley,et al.  Save Kazakhstan's shrinking Lake Balkhash , 2020, Science.

[5]  J. Löndahl,et al.  Exhaled respiratory particles during singing and talking , 2020, Aerosol Science and Technology.

[6]  T. Greenhalgh,et al.  Two metres or one: what is the evidence for physical distancing in covid-19? , 2020, BMJ.

[7]  Patricia Harrington,et al.  SARS-CoV-2 detection, viral load and infectivity over the course of an infection , 2020, Journal of Infection.

[8]  V. Soriano,et al.  Inoculum at the time of SARS-CoV-2 exposure and risk of disease severity , 2020, International Journal of Infectious Diseases.

[9]  Dong Yang,et al.  Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19 , 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[10]  J. Hoit,et al.  Influence of continuous speaking on ventilation. , 2000, Journal of speech, language, and hearing research : JSLHR.

[11]  F. Cerny,et al.  Effects of varied vocal intensity on ventilation and energy expenditure in women and men. , 1998, Journal of speech, language, and hearing research : JSLHR.