Should Return to Sport be Delayed Until 2 Years After Anterior Cruciate Ligament Reconstruction? Biological and Functional Considerations

Anterior cruciate ligament (ACL) tears are common knee injuries sustained by athletes during sports participation. A devastating complication of returning to sport following ACL reconstruction (ACLR) is a second ACL injury. Strong evidence now indicates that younger, more active athletes are at particularly high risk for a second ACL injury, and this risk is greatest within the first 2 years following ACLR. Nearly one-third of the younger cohort that resumes sports participation will sustain a second ACL injury within the first 2 years after ACLR. The evidence indicates that the risk of second injury may abate over this time period. The incidence rate of second injuries in the first year after ACLR is significantly greater than the rate in the second year. The lower relative risk in the second year may be related to athletes achieving baseline joint health and function well after the current expected timeline (6–12 months) to be released to unrestricted activity. This highlights a considerable debate in the return to sport decision process as to whether an athlete should wait until 2 years after ACLR to return to unrestricted sports activity. In this review, we present evidence in the literature that athletes achieve baseline joint health and function approximately 2 years after ACLR. We postulate that delay in returning to sports for nearly 2 years will significantly reduce the incidence of second ACL injuries.

[1]  M. Schurz,et al.  "Ligamentization" in hamstring tendon grafts after anterior cruciate ligament reconstruction: a systematic review of the literature and a glimpse into the future. , 2013, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[2]  Freddie H. Fu,et al.  Anatomic anterior cruciate ligament (ACL) reconstruction: a global perspective. Part 1 , 2014, Knee Surgery, Sports Traumatology, Arthroscopy.

[3]  David Logerstedt,et al.  Gait Patterns Differ Between ACL-Reconstructed Athletes Who Pass Return-to-Sport Criteria and Those Who Fail , 2013, The American journal of sports medicine.

[4]  T. Hewett,et al.  Strength Asymmetry and Landing Mechanics at Return to Sport after Anterior Cruciate Ligament Reconstruction. , 2015, Medicine and science in sports and exercise.

[5]  B. Koes,et al.  Follow-up of posttraumatic ligamentous and meniscal knee lesions detected at MR imaging: systematic review. , 2006, Radiology.

[6]  J. Mink,et al.  Occult cartilage and bone injuries of the knee: detection, classification, and assessment with MR imaging. , 1989, Radiology.

[7]  Jyrki Kettunen,et al.  Isokinetic quadriceps and hamstring muscle strength and knee function 5 years after anterior cruciate ligament reconstruction: comparison between bone-patellar tendon-bone and hamstring tendon autografts , 2008, Knee Surgery, Sports Traumatology, Arthroscopy.

[8]  Freddie H. Fu,et al.  Can Joint Contact Dynamics Be Restored by Anterior Cruciate Ligament Reconstruction? , 2013, Clinical orthopaedics and related research.

[9]  K. Kawasaki,et al.  Induction of somatosensory evoked potentials by mechanical stimulation in reconstructed anterior cruciate ligaments. , 2002, The Journal of bone and joint surgery. British volume.

[10]  Kate E. Webster,et al.  Younger Patients Are at Increased Risk for Graft Rupture and Contralateral Injury After Anterior Cruciate Ligament Reconstruction , 2014, The American journal of sports medicine.

[11]  S. Bierma-Zeinstra,et al.  Bone mineral density changes in the knee following anterior cruciate ligament rupture. , 2014, Osteoarthritis and cartilage.

[12]  Kurt P Spindler,et al.  Ipsilateral Graft and Contralateral ACL Rupture at Five Years or More Following ACL Reconstruction , 2011 .

[13]  L. Salmon,et al.  Clinical Results and Risk Factors for Reinjury 15 Years After Anterior Cruciate Ligament Reconstruction , 2012, The American journal of sports medicine.

[14]  Freddie H. Fu,et al.  Anterior cruciate ligament healing and advances in imaging. , 2013, Clinics in Sports Medicine.

[15]  E. Delahunt,et al.  Lower limb kinematic alterations during drop vertical jumps in female athletes who have undergone anterior cruciate ligament reconstruction , 2012, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[16]  N. Kitamura,et al.  Prospective clinical comparisons of semitendinosus versus semitendinosus and gracilis tendon autografts for anatomic double-bundle anterior cruciate ligament reconstruction , 2013, Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association.

[17]  Gregory D Myer,et al.  Risk of Secondary Injury in Younger Athletes After Anterior Cruciate Ligament Reconstruction , 2016, The American journal of sports medicine.

[18]  J. L. Marshall,et al.  Anterior cruciate ligament replacement using patellar tendon. An evaluation of graft revascularization in the dog. , 1982, The Journal of bone and joint surgery. American volume.

[19]  J. Bellemans,et al.  The “Ligamentization” Process in Anterior Cruciate Ligament Reconstruction , 2011, The American journal of sports medicine.

[20]  Evangelos Pappas,et al.  Asymmetries in functional hop tests, lower extremity kinematics, and isokinetic strength persist 6 to 9 months following anterior cruciate ligament reconstruction. , 2013, The Journal of orthopaedic and sports physical therapy.

[21]  L. Engebretsen,et al.  Lower Risk of Revision With Patellar Tendon Autografts Compared With Hamstring Autografts , 2014, The American journal of sports medicine.

[22]  I. Holm,et al.  The Long-term Effect of 2 Postoperative Rehabilitation Programs After Anterior Cruciate Ligament Reconstruction , 2009, The American journal of sports medicine.

[23]  Abbey C. Thomas,et al.  Maximizing quadriceps strength after ACL reconstruction. , 2008, Clinics in sports medicine.

[24]  K. Del Tredici,et al.  Reconstructed anterior cruciate ligaments using patellar tendon ligament grafts: diagnostic value of contrast-enhanced MRI in a 2-year follow-up regimen , 2001, European Radiology.

[25]  L. Engebretsen,et al.  Increased Risk of Revision With Hamstring Tendon Grafts Compared With Patellar Tendon Grafts After Anterior Cruciate Ligament Reconstruction , 2014, The American journal of sports medicine.

[26]  Shiyi Chen,et al.  Difference in Graft Maturity of the Reconstructed Anterior Cruciate Ligament 2 Years Postoperatively , 2012, The American journal of sports medicine.

[27]  W. Breidahl,et al.  Anterior cruciate ligament reconstruction using autologous double hamstrings: a comparison of standard versus minimal debridement techniques using MRI to assess revascularisation. A randomised prospective study with a one-year follow-up. , 2007, The Journal of bone and joint surgery. British volume.

[28]  A. K. Aune,et al.  Four-Strand Hamstring Tendon Autograft Compared with Patellar Tendon-Bone Autograft for Anterior Cruciate Ligament Reconstruction , 2001, The American journal of sports medicine.

[29]  B. Zerahn,et al.  Bone mineral density in the proximal tibia and calcaneus before and after arthroscopic reconstruction of the anterior cruciate ligament. , 2006, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[30]  L. Engebretsen,et al.  A sixteen-year follow-up of three operative techniques for the treatment of acute ruptures of the anterior cruciate ligament. , 2006, The Journal of bone and joint surgery. American volume.

[31]  E. Dabezies,et al.  Mechanoreceptors in the human anterior cruciate ligament , 1986, The Anatomical record.

[32]  F R Noyes,et al.  Knee rehabilitation after anterior cruciate ligament reconstruction and repair , 1981, The Journal of orthopaedic and sports physical therapy.

[33]  L. Salmon,et al.  Survival of the Anterior Cruciate Ligament Graft and the Contralateral ACL at a Minimum of 15 Years , 2012, The American journal of sports medicine.

[34]  D. Pedersen,et al.  Bone bruises in anterior cruciate ligament injured knee and long-term outcomes. A review of the evidence , 2015, Open access journal of sports medicine.

[35]  Scott M Lephart,et al.  Proprioceptive deficits after ACL injury: are they clinically relevant? , 2011, British Journal of Sports Medicine.

[36]  P. Dyhre‐Poulsen,et al.  Muscular reflexes elicited by electrical stimulation of the anterior cruciate ligament in humans. , 2000, Journal of applied physiology.

[37]  Haris S. Vasiliadis,et al.  The influence of graft choice on isokinetic muscle strength 4–24 months after anterior cruciate ligament reconstruction , 2011, Knee Surgery, Sports Traumatology, Arthroscopy.

[38]  B. Koes,et al.  Clinical Consequences of Posttraumatic Bone Bruise in the Knee , 2007, The American journal of sports medicine.

[39]  Absence of sensory function in the reconstructed anterior cruciate ligament. , 2011, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[40]  T. Hewett,et al.  The impact of quadriceps femoris strength asymmetry on functional performance at return to sport following anterior cruciate ligament reconstruction. , 2012, The Journal of orthopaedic and sports physical therapy.

[41]  S. Dye,et al.  Restoration of osseous homeostasis after anterior cruciate ligament reconstruction , 1993, The American journal of sports medicine.

[42]  Brian J. Cole,et al.  Functional Performance Testing After Anterior Cruciate Ligament Reconstruction , 2014, Orthopaedic journal of sports medicine.

[43]  S. Dye,et al.  The use of scintigraphy to detect increased osseous metabolic activity about the knee. , 1993, Instructional course lectures.

[44]  N. Adachi,et al.  The regeneration of sensory neurones in the reconstruction of the anterior cruciate ligament , 1999 .

[45]  Y. Hua,et al.  Comparison of tendon–bone healing between autografts and allografts after anterior cruciate ligament reconstruction using magnetic resonance imaging , 2015, Knee Surgery, Sports Traumatology, Arthroscopy.

[46]  J. Bullock-Saxton,et al.  A 6-Year Follow-up of the Effect of Graft Site on Strength, Stability, Range of Motion, Function, and Joint Degeneration after Anterior Cruciate Ligament Reconstruction , 2007, The American journal of sports medicine.

[47]  Michael J Stuart,et al.  Femoral Tunnel Malposition in ACL Revision Reconstruction , 2012, The Journal of Knee Surgery.

[48]  T. Hewett,et al.  Are Female Soccer Players at an Increased Risk of Second Anterior Cruciate Ligament Injury Compared With Their Athletic Peers? , 2016, The American journal of sports medicine.

[49]  L. Micheli,et al.  Mechanoreceptors in human cruciate ligaments. A histological study. , 1984, The Journal of bone and joint surgery. American volume.

[50]  Kevin R Ford,et al.  The Relationship of Hamstrings and Quadriceps Strength to Anterior Cruciate Ligament Injury in Female Athletes , 2009, Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine.

[51]  Patrick Smolinski,et al.  Biomechanical comparison of different graft positions for single-bundle anterior cruciate ligament reconstruction , 2012, Knee Surgery, Sports Traumatology, Arthroscopy.

[52]  J. Nyland,et al.  Osseous deficits after anterior cruciate ligament injury and reconstruction: a systematic literature review with suggestions to improve osseous homeostasis. , 2010, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[53]  T. Hewett,et al.  Incidence of Contralateral and Ipsilateral Anterior Cruciate Ligament (ACL) Injury After Primary ACL Reconstruction and Return to Sport , 2012, Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine.

[54]  K. Crossley,et al.  Knee kinematics and joint moments during gait following anterior cruciate ligament reconstruction: a systematic review and meta-analysis , 2015, British Journal of Sports Medicine.

[55]  L. Engebretsen,et al.  Simple decision rules can reduce reinjury risk by 84% after ACL reconstruction: the Delaware-Oslo ACL cohort study , 2016, British Journal of Sports Medicine.

[56]  L. Snyder-Mackler,et al.  Sex-specific gait adaptations prior to and up to 6 months after anterior cruciate ligament reconstruction. , 2015, The Journal of orthopaedic and sports physical therapy.

[57]  M. Kurosaka,et al.  Light and electron microscopic study of remodeling and maturation process in autogenous graft for anterior cruciate ligament reconstruction. , 1993, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[58]  L. Salmon,et al.  Fifteen-Year Outcome of Endoscopic Anterior Cruciate Ligament Reconstruction With Patellar Tendon Autograft for “Isolated” Anterior Cruciate Ligament Tear , 2011, The American journal of sports medicine.

[59]  B. Koes,et al.  Magnetic Resonance Imaging Abnormalities in Symptomatic and Contralateral Knees , 2006, The American journal of sports medicine.

[60]  P. Kannus,et al.  Bone mineral density and muscle strength of lower extremities after long-term strength training, subsequent knee ligament injury and rehabilitation: a unique 2-year follow-up of a 26-year-old female student. , 1994, Bone.

[61]  D. Altchek,et al.  Anterior cruciate ligament revision: double-bundle augmentation of primary vertical graft. , 2006, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[62]  K. Refshauge,et al.  Incidence and risk factors for graft rupture and contralateral rupture after anterior cruciate ligament reconstruction. , 2005, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[63]  B. Boden,et al.  Mechanisms of anterior cruciate ligament injury. , 2000, Orthopedics.

[64]  Michael F. Vignos,et al.  American Society of Biomechanics Clinical Biomechanics Award 2015: MRI assessments of cartilage mechanics, morphology and composition following reconstruction of the anterior cruciate ligament. , 2016, Clinical biomechanics.

[65]  I. Kingma,et al.  A systematic review of postural control during single-leg stance in patients with untreated anterior cruciate ligament injury , 2013, Knee Surgery, Sports Traumatology, Arthroscopy.

[66]  K. Shelbourne,et al.  Arthroscopic and histologic analysis of human patellar tendon autografts used for anterior cruciate ligament reconstruction , 1993, The American journal of sports medicine.

[67]  T. Hewett,et al.  Limb Asymmetries in Landing and Jumping 2 Years Following Anterior Cruciate Ligament Reconstruction , 2007, Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine.

[68]  K. Spindler,et al.  Prospective study of osseous, articular, and meniscal lesions in recent anterior cruciate ligament tears by magnetic resonance imaging and arthroscopy , 1993, The American journal of sports medicine.

[69]  G. Barrett,et al.  Age, Graft Size, and Tegner Activity Level as Predictors of Failure in Anterior Cruciate Ligament Reconstruction With Hamstring Autograft , 2013, The American journal of sports medicine.

[70]  E. Delahunt,et al.  Hip and knee joint kinematics during a diagonal jump landing in anterior cruciate ligament reconstructed females. , 2012, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[71]  Kevin R Ford,et al.  Incidence of Second ACL Injuries 2 Years After Primary ACL Reconstruction and Return to Sport , 2014, The American journal of sports medicine.

[72]  R. D'ambrosia,et al.  The synergistic action of the anterior cruciate ligament and thigh muscles in maintaining joint stability , 1987, The American journal of sports medicine.

[73]  M. Inacio,et al.  Reconstruction of the anterior cruciate ligament: association of graft choice with increased risk of early revision. , 2013, The bone & joint journal.

[74]  A. Nitz,et al.  Review of the afferent neural system of the knee and its contribution to motor learning. , 1994, The Journal of orthopaedic and sports physical therapy.

[75]  C. Kaeding,et al.  Activity Level and Graft Type as Risk Factors for Anterior Cruciate Ligament Graft Failure , 2009, The American journal of sports medicine.

[76]  L. Engebretsen,et al.  How does a combined preoperative and postoperative rehabilitation programme influence the outcome of ACL reconstruction 2 years after surgery? A comparison between patients in the Delaware-Oslo ACL Cohort and the Norwegian National Knee Ligament Registry , 2014, British Journal of Sports Medicine.

[77]  岩佐 潤二 Proprioceptive improvement in knees with anterior cruciate ligament reconstruction , 2002 .

[78]  F. Harrell,et al.  Which Preoperative Factors, Including Bone Bruise, Are Associated With Knee Pain/Symptoms at Index Anterior Cruciate Ligament Reconstruction (ACLR)? , 2010, The American journal of sports medicine.

[79]  A. Lindstrand,et al.  Bilateral proprioceptive defects in patients with a unilateral anterior cruciate ligament reconstruction: A comparison between patients and healthy individuals , 2000, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[80]  T. Hewett,et al.  Biomechanical Measures during Landing and Postural Stability Predict Second Anterior Cruciate Ligament Injury after Anterior Cruciate Ligament Reconstruction and Return to Sport , 2010, The American journal of sports medicine.

[81]  A. Vellet,et al.  Occult posttraumatic osteochondral lesions of the knee: prevalence, classification, and short-term sequelae evaluated with MR imaging. , 1991, Radiology.

[82]  B. Beynnon,et al.  Proprioception after anterior cruciate ligament reconstruction with and without bracing , 1999, Knee Surgery, Sports Traumatology, Arthroscopy.

[83]  L. Snyder-Mackler,et al.  Quadriceps strength and weight acceptance strategies continue to improve two years after anterior cruciate ligament reconstruction. , 2011, Journal of biomechanics.

[84]  M. Lind,et al.  Incidence and Outcome After Revision Anterior Cruciate Ligament Reconstruction , 2012, The American journal of sports medicine.

[85]  Dean C Taylor,et al.  Graft size and patient age are predictors of early revision after anterior cruciate ligament reconstruction with hamstring autograft. , 2012, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[86]  L. Salmon,et al.  Fifteen-Year Survival of Endoscopic Anterior Cruciate Ligament Reconstruction in Patients Aged 18 Years and Younger , 2015, The American journal of sports medicine.

[87]  Freddie H. Fu,et al.  Comparison of In Situ Forces and Knee Kinematics in Anteromedial and High Anteromedial Bundle Augmentation for Partially Ruptured Anterior Cruciate Ligament , 2011, The American journal of sports medicine.

[88]  A Guermazi,et al.  MRI-detected subchondral bone marrow signal alterations of the knee joint: terminology, imaging appearance, relevance and radiological differential diagnosis. , 2009, Osteoarthritis and cartilage.

[89]  Two- to 4-Year Follow-up to a Comparison of Home Versus Physical Therapy-Supervised Rehabilitation Programs After Anterior Cruciate Ligament Reconstruction , 2011 .

[90]  D. W. Jackson,et al.  Occult osseous lesions documented by magnetic resonance imaging associated with anterior cruciate ligament ruptures. , 1991, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[91]  A. Weiler,et al.  Biomechanical Properties and Vascularity of an Anterior Cruciate Ligament Graft can be Predicted by Contrast-Enhanced Magnetic Resonance Imaging , 2001, The American journal of sports medicine.

[92]  D. Hedden,et al.  Proprioception in Anterior Cruciate Ligament-Deficient and Reconstructed Knees , 1996, The American journal of sports medicine.

[93]  K. Webster,et al.  Longitudinal changes in knee joint biomechanics during level walking following anterior cruciate ligament reconstruction surgery. , 2012, Gait & posture.

[94]  A. Weiler,et al.  Graft remodeling and ligamentization after cruciate ligament reconstruction , 2008, Knee Surgery, Sports Traumatology, Arthroscopy.

[95]  Link,et al.  Anatomic anterior cruciate ligament reconstruction : a changing paradigm , 2010 .

[96]  A. Natri,et al.  Effect of Anterior Cruciate Ligament Injury of the Knee on Bone Mineral Density of the Spine and Affected Lower Extremity: A Prospective One-Year Follow-Up Study , 1999, Calcified Tissue International.

[97]  D. E. Cooper,et al.  Descriptive Epidemiology of the Multicenter ACL Revision Study (MARS) Cohort , 2010, The American journal of sports medicine.

[98]  Brian J. Cole,et al.  Incidence and Trends of Anterior Cruciate Ligament Reconstruction in the United States , 2014, The American journal of sports medicine.

[99]  Michael D. Lewek,et al.  A systematic review of evidence for anterior cruciate ligament rehabilitation: how much and what type? , 2004 .

[100]  I. Holm,et al.  Preoperative quadriceps strength is a significant predictor of knee function two years after anterior cruciate ligament reconstruction , 2009, British Journal of Sports Medicine.

[101]  R. Buzzi,et al.  Anterior cruciate ligament reconstruction: bone-patellar tendon-bone compared with double semitendinosus and gracilis tendon grafts. A prospective, randomized clinical trial. , 2004, The Journal of bone and joint surgery. American volume.

[102]  D. Dahm,et al.  Lateral Tibial Posterior Slope Is Increased in Patients With Early Graft Failure After Anterior Cruciate Ligament Reconstruction , 2015, The American journal of sports medicine.

[103]  Gregory D Myer,et al.  Strategies for enhancing proprioception and neuromuscular control of the knee. , 2002, Clinical orthopaedics and related research.

[104]  S. Zaffagnini,et al.  Neoligamentization process of BTPB used for ACL graft: histological evaluation from 6 months to 10 years. , 2007, The Knee.

[105]  K. Shelbourne,et al.  Accelerated rehabilitation after anterior cruciate ligament reconstruction , 1990, The American journal of sports medicine.

[106]  E. Anitua,et al.  Ligamentization of tendon grafts treated with an endogenous preparation rich in growth factors: gross morphology and histology. , 2010, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[107]  T. Thillemann,et al.  Increased risk of revision after anteromedial compared with transtibial drilling of the femoral tunnel during primary anterior cruciate ligament reconstruction: results from the Danish Knee Ligament Reconstruction Register. , 2013, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[108]  J. Nyland,et al.  The Effect of a Geographic Lateral Bone Bruise on Knee Inflammation after Acute Anterior Cruciate Ligament Rupture* , 2000, The American journal of sports medicine.

[109]  R. Buzzi,et al.  Anterior Cruciate Ligament Reconstruction: Bone-Patellar Tendon-Bone Compared with Double Semitendinosus and Gracilis Tendon Grafts , 2004 .

[110]  K. Shelbourne,et al.  Incidence of Subsequent Injury to Either Knee within 5 Years after Anterior Cruciate Ligament Reconstruction with Patellar Tendon Autograft , 2009, The American journal of sports medicine.

[111]  E. Otten,et al.  Return of normal gait as an outcome measurement in acl reconstructed patients. A systematic review. , 2013, International journal of sports physical therapy.

[112]  F. Noyes,et al.  Prevalence of Nonanatomical Graft Placement in a Series of Failed Anterior Cruciate Ligament Reconstructions , 2010, The American journal of sports medicine.

[113]  P. Kannus,et al.  Muscle Strength Evaluations after ACL Reconstruction , 2007, International journal of sports medicine.

[114]  C. Kaeding,et al.  Intra-articular Findings in Primary and Revision Anterior Cruciate Ligament Reconstruction Surgery , 2011, The American journal of sports medicine.

[115]  S. Tashman,et al.  Effects of anterior cruciate ligament reconstruction on in vivo, dynamic knee function. , 2013, Clinics in sports medicine.

[116]  G. Monnier,et al.  Analysis of return to competition and repeat rupture for 298 anterior cruciate ligament reconstructions with patellar or hamstring tendon autograft in sportspeople. , 2010, Annals of physical and rehabilitation medicine.

[117]  M. Inacio,et al.  Incidence of Postoperative Anterior Cruciate Ligament Reconstruction Infections , 2013, The American journal of sports medicine.

[118]  K. Shelbourne,et al.  Accelerated Rehabilitation after Anterior Cruciate Ligament Reconstruction1 , 1992 .

[119]  T. Järvelä,et al.  Double-bundle versus single-bundle anterior cruciate ligament reconstruction. , 2013, Clinics in sports medicine.

[120]  W. Akeson,et al.  The phenomenon of “Ligamentization”: Anterior cruciate ligament reconstruction with autogenous patellar tendon , 1986, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[121]  D. Muscolo,et al.  Magnetic resonance imaging follow-up study of bone bruises associated with anterior cruciate ligament ruptures. , 2001, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[122]  M. Lind,et al.  Risk for Revision After Anterior Cruciate Ligament Reconstruction Is Higher Among Adolescents , 2014, Orthopaedic journal of sports medicine.

[123]  Bryan T. Hanypsiak,et al.  Twelve-Year Follow-up on Anterior Cruciate Ligament Reconstruction , 2008, The American journal of sports medicine.

[124]  R. Burchette,et al.  A Prospective Randomized Study of Anterior Cruciate Ligament Reconstruction , 2007, The American journal of sports medicine.