An unusual polyp: a pedunculated leiomyoma of the sigmoid colon.

tion of scant rectal bleeding that occurred with bowel movements. He deniedweight loss, fevers, fatigue, or alarm symptoms, and reported no family history of polyps, colorectal cancer, or intestinal disorders. His past medical history and physical examination including a digital rectal examination were unremarkable. Colonoscopy demonstrated a single 1.2 cm pedunculated polyp within the lumen of the sigmoid colon (●" Fig. 1). The polyp, which was glistening, smooth, round, and on a minute stalk, was removed in its entirety by hot-snare polypectomy (●" Fig. 2). Histologic sections of the polyp revealed normal mucosa overlying a well-circumscribed proliferation of bland, brightly eosinophilic spindle cells that were arising in association with the muscularis mucosae (●" Fig. 3). On further staining, the neoplastic cells were positive for smooth muscle actin (●" Fig. 4) and negative for CD117 (not shown), consistent with a diagnosis of leiomyoma of the sigmoid colon. Smoothmuscle tumors, which include benign leiomyomas and malignant leiomyosarcomas, are the most common, nonepithelial tumors of the gastrointestinal tract [1]. The colon and rectum are rare sites for leiomyomas, representing 3% of all gastrointestinal leiomyomas [2]. The commonest location in the large bowel is the descending and sigmoid colon [3]. The peak incidence occurs in the third decade of life and there is a slight female predominance [3]. Leiomyomas can present with a variety of symptoms including abdominal pain, constipation, weight loss, and bleeding [3]. The tumors arise from themuscularis mucosa or propria, or vascular smooth muscle [1]. On colonoscopy leiomyomas are intramural or pedunculated lesions that can be similar in appearance to adenomatous polyps [4]. Radiologic imaging such as computed tomography (CT) with colonography, barium enemas, and magnetic resonance imaging (MRI) can be useful diagnostic adjuncts [5]. Treatment includes complete removal, and recurrences are extremely rare. For small, pedunculated lesions, endoscopic snare polypectomy is a useful approach; for larger tumors or those where malignancy is a concern, surgical resection with wide margins is advocated [4].