PTH Induces Systemically Administered Mesenchymal Stem Cells to Migrate to and Regenerate Spine Injuries.

[1]  Xu Yang,et al.  Intermittent PTH administration and mechanical loading are anabolic for periprosthetic cancellous bone , 2015, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[2]  Jiefu Song,et al.  Single and Combined use of Human Parathyroid Hormone (PTH) (1-34) on Areal Bone Mineral Density (aBMD) in Postmenopausal Women with Osteoporosis: Evidence Based on 9 RCTs , 2014, Medical science monitor : international medical journal of experimental and clinical research.

[3]  J. Bouler,et al.  Vertebroplasty using bisphosphonate-loaded calcium phosphate cement in a standardized vertebral body bone defect in an osteoporotic sheep model. , 2014, Acta biomaterialia.

[4]  R. Su,et al.  Establishing a rapid animal model of osteoporosis with ovariectomy plus low calcium diet in rats. , 2014, International journal of clinical and experimental pathology.

[5]  A. Capone,et al.  Orthopaedic surgeons' strategies in pharmacological treatment of fragility fractures. , 2014, Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases.

[6]  A. Langheinrich,et al.  Bone matrix, cellularity, and structural changes in a rat model with high-turnover osteoporosis induced by combined ovariectomy and a multiple-deficient diet. , 2014, The American journal of pathology.

[7]  G. Balian,et al.  A novel strategy of spine defect repair with a degradable bioactive scaffold preloaded with adipose-derived stromal cells. , 2014, The spine journal : official journal of the North American Spine Society.

[8]  W. Tawackoli,et al.  PTH promotes allograft integration in a calvarial bone defect. , 2013, Molecular pharmaceutics.

[9]  O. Jiroušek,et al.  The combination of mesenchymal stem cells and a bone scaffold in the treatment of vertebral body defects , 2013, European Spine Journal.

[10]  David J. Olivos,et al.  Reversing bone loss by directing mesenchymal stem cells to bone , 2013, Stem cells.

[11]  E. Schwarz,et al.  PTH‐enhanced structural allograft healing is associated with decreased angiopoietin‐2–mediated arteriogenesis, mast cell accumulation, and fibrosis , 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[12]  L. Qin,et al.  Amphiregulin-EGFR Signaling Mediates the Migration of Bone Marrow Mesenchymal Progenitors toward PTH-Stimulated Osteoblasts and Osteocytes , 2012, PloS one.

[13]  F. Dazzi,et al.  Mesenchymal stromal cells: a key player in ‘innate tolerance’? , 2012, Immunology.

[14]  L. Xian,et al.  Parathyroid hormone induces differentiation of mesenchymal stromal/stem cells by enhancing bone morphogenetic protein signaling , 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[15]  J. Bechtold,et al.  Systemic intermittent parathyroid hormone treatment improves osseointegration of press-fit inserted implants in cancellous bone , 2012, Acta orthopaedica.

[16]  Genlin Wang,et al.  Evaluation of Calcium Phosphate and Calcium Sulfate as Injectable Bone Cements in Sheep Vertebrae , 2012, Journal of spinal disorders & techniques.

[17]  C. -. Chen,et al.  Bone healing response to a synthetic calcium sulfate/β-tricalcium phosphate graft material in a sheep vertebral body defect model , 2012, Journal of biomedical materials research. Part B, Applied biomaterials.

[18]  M. Aller,et al.  Immunosuppressive properties of mesenchymal stem cells: advances and applications. , 2012, Current molecular medicine.

[19]  K. Lam,et al.  Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass , 2012, Nature Medicine.

[20]  W. Tawackoli,et al.  Gene-modified adult stem cells regenerate vertebral bone defect in a rat model. , 2011, Molecular pharmaceutics.

[21]  G. Holzer,et al.  Parathyroid hormone 1-84 accelerates fracture-healing in pubic bones of elderly osteoporotic women. , 2011, The Journal of bone and joint surgery. American volume.

[22]  G. Hampson,et al.  The pathogenesis, diagnosis, investigation and management of osteoporosis , 2011, Journal of Clinical Pathology.

[23]  R. David,et al.  Parathyroid hormone is a DPP-IV inhibitor and increases SDF-1-driven homing of CXCR4(+) stem cells into the ischaemic heart. , 2011, Cardiovascular research.

[24]  G. Balian,et al.  Use of a bioactive scaffold for the repair of bone defects in a novel reproducible vertebral body defect model. , 2010, Bone.

[25]  Steven A Goldstein,et al.  The effects of axial displacement on fracture callus morphology and MSC homing depend on the timing of application. , 2010, Bone.

[26]  H. Genant,et al.  Teriparatide for acceleration of fracture repair in humans: A prospective, randomized, double‐blind study of 102 postmenopausal women with distal radial fractures , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[27]  William Hollingworth,et al.  A randomized trial of vertebroplasty for osteoporotic spinal fractures. , 2009, The New England journal of medicine.

[28]  R. Buchbinder,et al.  A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures. , 2009, The New England journal of medicine.

[29]  Joshua A Hirsch,et al.  Position statement on percutaneous vertebral augmentation: a consensus statement developed by the American Society of Interventional and Therapeutic Neuroradiology, Society of Interventional Radiology, American Association of Neurological Surgeons/Congress of Neurological Surgeons, and American Soci , 2009, Journal of vascular and interventional radiology : JVIR.

[30]  Joseph C. Wu,et al.  Long term non-invasive imaging of embryonic stem cells using reporter genes , 2009, Nature Protocols.

[31]  A. Geiser,et al.  Longitudinal in vivo analysis of the region-specific efficacy of parathyroid hormone in a rat cortical defect model. , 2009, Endocrinology.

[32]  E. Schwarz,et al.  Teriparatide (1‐34 human PTH) regulation of osterix during fracture repair , 2008, Journal of cellular biochemistry.

[33]  Tae-Hong Lim,et al.  Vertebroplasty comparing injectable calcium phosphate cement compared with polymethylmethacrylate in a unique canine vertebral body large defect model. , 2008, The spine journal : official journal of the North American Spine Society.

[34]  Phillip C. Yang,et al.  Comparison of Reporter Gene and Iron Particle Labeling for Tracking Fate of Human Embryonic Stem Cells and Differentiated Endothelial Cells in Living Subjects , 2008, Stem cells.

[35]  G. Pelled,et al.  Ultrasound-based nonviral gene delivery induces bone formation in vivo , 2008, Gene Therapy.

[36]  Giselle Chamberlain,et al.  Concise Review: Mesenchymal Stem Cells: Their Phenotype, Differentiation Capacity, Immunological Features, and Potential for Homing , 2007, Stem cells.

[37]  T. Rando,et al.  Intrinsic Changes and Extrinsic Influences of Myogenic Stem Cell Function During Aging , 2007, Stem Cell Reviews.

[38]  R. Recker,et al.  Increases in BMD Correlate With Improvements in Bone Microarchitecture With Teriparatide Treatment in Postmenopausal Women With Osteoporosis , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[39]  R. Lindsay,et al.  Effects Of a One‐Month Treatment With PTH(1–34) on Bone Formation on Cancellous, Endocortical, and Periosteal Surfaces of the Human Ilium , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[40]  R. Lindsay,et al.  Effect of Recombinant Human Parathyroid Hormone (1-84) on Vertebral Fracture and Bone Mineral Density in Postmenopausal Women with Osteoporosis , 2007, Annals of Internal Medicine.

[41]  J. Massie,et al.  A rat osteoporotic spine model for the evaluation of bioresorbable bone cements. , 2006, The spine journal : official journal of the North American Spine Society.

[42]  A. Turner,et al.  In vivo BMP-7 (OP-1) enhancement of osteoporotic vertebral bodies in an ovine model. , 2006, The spine journal : official journal of the North American Spine Society.

[43]  Albert G. Veldhuizen,et al.  Percutaneous vertebroplasty as a treatment for osteoporotic vertebral compression fractures: a systematic review , 2006, European Spine Journal.

[44]  M. Liebergall,et al.  Nucleofection-based ex vivo nonviral gene delivery to human stem cells as a platform for tissue regeneration. , 2006, Tissue engineering.

[45]  Younghun Jung,et al.  Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing. , 2006, Bone.

[46]  Andrew Scutt,et al.  Aging of mesenchymal stem cells , 2006, Ageing Research Reviews.

[47]  B. Mitlak,et al.  Enhancement of experimental fracture-healing by systemic administration of recombinant human parathyroid hormone (PTH 1-34). , 2005, The Journal of bone and joint surgery. American volume.

[48]  S. Rabbani,et al.  Induction of osteoblast differentiation indexes by PTHrP in MG-63 cells involves multiple signaling pathways. , 2001, American journal of physiology. Endocrinology and metabolism.

[49]  J. Reginster,et al.  Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis. , 2001, The New England journal of medicine.

[50]  A. Caplan,et al.  A Quadripotential Mesenchymal Progenitor Cell Isolated from the Marrow of an Adult Mouse , 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[51]  J. Eisman,et al.  Mortality after all major types of osteoporotic fracture in men and women: an observational study , 1999, The Lancet.

[52]  J. Sprent,et al.  Lymphocyte activation , 1994, Journal of cellular biochemistry.

[53]  Gadi Pelled,et al.  Microcomputed tomography–based structural analysis of various bone tissue regeneration models , 2011, Nature Protocols.

[54]  Genlin Wang,et al.  A novel sheep vertebral bone defect model for injectable bioactive vertebral augmentation materials , 2011, Journal of materials science. Materials in medicine.

[55]  Gadi Pelled,et al.  Targeted gene-and-host progenitor cell therapy for nonunion bone fracture repair. , 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

[56]  B. Clarke,et al.  Effect of Recombinant Human Parathyroid Hormone (1-84) on Vertebral Fracture and Bone Mineral Density in Postmenopausal Women with Osteoporosis: A Randomized Trial , 2008 .

[57]  真鍋 健史 Human parathyroid hormone (1-34) accelerates natural fracture healing process in the femoral osteotomy model of cynomolgus monkeys , 2008 .

[58]  E. Ravussin,et al.  Isolation of human adipose-derived stem cells from biopsies and liposuction specimens. , 2008, Methods in molecular biology.

[59]  A. Scutt,et al.  Stolzing A Aging of mesenchymal stem cells , 2006 .