The mitochondrial peptidase, neurolysin, regulates respiratory chain supercomplex formation and is necessary for AML viability
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Gary D Bader | M. Minden | B. Raught | Steven M. Chan | S. Kornblau | Y. Qiu | J. St-Germain | R. Hurren | Xiaoming Wang | N. Maclean | A. Schimmer | T. Horton | V. Voisin | S. Mirali | Changjiang Xu | M. Gronda | Y. Jitkova | A. Arruda | Jonathan R St-Germain | D. Sharon | B. Nachmias | F. Hoff | Aaron Botham
[1] Austin E. Gillen,et al. Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia , 2018, Nature Medicine.
[2] Beth Wilmot,et al. Functional Genomic Landscape of Acute Myeloid Leukemia , 2018, Nature.
[3] S. Phanse,et al. Acyldepsipeptide Analogs Dysregulate Human Mitochondrial ClpP Protease Activity and Cause Apoptotic Cell Death. , 2018, Cell chemical biology.
[4] M. Ankarcrona,et al. Mechanism of Peptide Binding and Cleavage by the Human Mitochondrial Peptidase Neurolysin. , 2017, Journal of molecular biology.
[5] J. A. Letts,et al. Clarifying the supercomplex: the higher-order organization of the mitochondrial electron transport chain , 2017, Nature Structural &Molecular Biology.
[6] J. Auwerx,et al. Enhanced Respiratory Chain Supercomplex Formation in Response to Exercise in Human Skeletal Muscle. , 2017, Cell metabolism.
[7] Claude Preudhomme,et al. A 17-gene stemness score for rapid determination of risk in acute leukaemia , 2016, Nature.
[8] I. Ezkurdia,et al. Mechanism of super-assembly of respiratory complexes III and IV , 2016, Nature.
[9] G. Bonvento,et al. Complex I assembly into supercomplexes determines differential mitochondrial ROS production in neurons and astrocytes , 2016, Proceedings of the National Academy of Sciences.
[10] J. A. Letts,et al. The architecture of respiratory supercomplexes , 2016, Nature.
[11] Evan G. Williams,et al. Systems proteomics of liver mitochondria function , 2016, Science.
[12] Gary D Bader,et al. miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells , 2016, Cancer cell.
[13] Gary D Bader,et al. miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells , 2016, Cancer cell.
[14] Gary D Bader,et al. Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia. , 2015, Cancer cell.
[15] Amber L. Couzens,et al. BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates* , 2015, Molecular & Cellular Proteomics.
[16] J. Dick,et al. AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress. , 2015, Blood.
[17] Paul N. Mortenson,et al. Allosteric Inhibition of the Neuropeptidase Neurolysin* , 2014, The Journal of Biological Chemistry.
[18] S. Carr,et al. Proteomic mapping of the human mitochondrial intermembrane space in live cells via ratiometric APEX tagging. , 2014, Molecular cell.
[19] F. Gozzo,et al. Neurolysin Knockout Mice Generation and Initial Phenotype Characterization* , 2014, The Journal of Biological Chemistry.
[20] Guomin Liu,et al. SAINTexpress: improvements and additional features in Significance Analysis of INTeractome software. , 2014, Journal of proteomics.
[21] J. Enríquez,et al. The function of the respiratory supercomplexes: the plasticity model. , 2014, Biochimica et biophysica acta.
[22] M. L. Genova,et al. Mitochondrial respiratory supercomplex association limits production of reactive oxygen species from complex I. , 2013, Antioxidants & redox signaling.
[23] Sara Cipolat,et al. Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency , 2013, Cell.
[24] C. López-Otín,et al. Supercomplex Assembly Determines Electron Flux in the Mitochondrial Electron Transport Chain , 2013, Science.
[25] S. Carr,et al. Proteomic Mapping of Mitochondria in Living Cells via Spatially Restricted Enzymatic Tagging , 2013, Science.
[26] John M. Ashton,et al. BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells. , 2013, Cell stem cell.
[27] J. Eng,et al. Comet: An open‐source MS/MS sequence database search tool , 2013, Proteomics.
[28] T. Langer,et al. Proteolytic control of mitochondrial function and morphogenesis. , 2013, Biochimica et biophysica acta.
[29] H. Shapiro,et al. JC-1: alternative excitation wavelengths facilitate mitochondrial membrane potential cytometry , 2012, Cell Death and Disease.
[30] G. Giaever,et al. Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia. , 2011, Cancer cell.
[31] Hyungwon Choi,et al. SAINT: Probabilistic Scoring of Affinity Purification - Mass Spectrometry Data , 2010, Nature Methods.
[32] H. Chan,et al. Structural and theoretical studies indicate that the cylindrical protease ClpP samples extended and compact conformations. , 2010, Structure.
[33] S. Shurtleff,et al. Clinical utility of microarray-based gene expression profiling in the diagnosis and subclassification of leukemia: report from the International Microarray Innovations in Leukemia Study Group. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[34] D. Clapham,et al. Genome-Wide RNAi Screen Identifies Letm1 as a Mitochondrial Ca2+/H+ Antiporter , 2009, Science.
[35] Toshihiko Oka,et al. Characterization of the mitochondrial protein LETM1, which maintains the mitochondrial tubular shapes and interacts with the AAA-ATPase BCS1L , 2008, Journal of Cell Science.
[36] Robert Burke,et al. ProteoWizard: open source software for rapid proteomics tools development , 2008, Bioinform..
[37] S. Liang,et al. An improved SUMO fusion protein system for effective production of native proteins , 2008, Protein science : a publication of the Protein Society.
[38] L. Scorrano,et al. LETM1, deleted in Wolf-Hirschhorn syndrome is required for normal mitochondrial morphology and cellular viability. , 2007, Human molecular genetics.
[39] J. Dick,et al. Direct evidence for cooperating genetic events in the leukemic transformation of normal human hematopoietic cells , 2005, Leukemia.
[40] M. Maurizi,et al. Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP. , 2004, Journal of structural biology.
[41] M. L. Genova,et al. The Mitochondrial Respiratory Chain Is Partially Organized in a Supercomplex Assembly , 2004, Journal of Biological Chemistry.
[42] M. Bauer,et al. Significance of Respirasomes for the Assembly/Stability of Human Respiratory Chain Complex I* , 2004, Journal of Biological Chemistry.
[43] Robertson Craig,et al. TANDEM: matching proteins with tandem mass spectra. , 2004, Bioinformatics.
[44] C. Bruno,et al. Respiratory complex III is required to maintain complex I in mammalian mitochondria. , 2004, Molecular cell.
[45] C. Eaves,et al. NOD/SCID mice engineered to express human IL-3, GM-CSF and Steel factor constitutively mobilize engrafted human progenitors and compromise human stem cell regeneration , 2004, Leukemia.
[46] F. Gozzo,et al. Novel Natural Peptide Substrates for Endopeptidase 24.15, Neurolysin, and Angiotensin-converting Enzyme* , 2003, The Journal of Biological Chemistry.
[47] K. Pfeiffer,et al. Supercomplexes in the respiratory chains of yeast and mammalian mitochondria , 2000, The EMBO journal.
[48] J. Roberts,et al. Neuropeptide specificity and inhibition of recombinant isoforms of the endopeptidase 3.4.24.16 family: comparison with the related recombinant endopeptidase 3.4.24.15. , 1998, Biochemical and biophysical research communications.
[49] A. Barrett,et al. Characterization of a Mitochondrial Metallopeptidase Reveals Neurolysin as a Homologue of Thimet Oligopeptidase (*) , 1995, The Journal of Biological Chemistry.
[50] F. Checler,et al. [36] Neurolysin: Purification and assays , 1995 .
[51] F. Checler,et al. Neurolysin: purification and assays. , 1995, Methods in enzymology.
[52] F. Checler,et al. Colocalization of neurotensin receptors and of the neurotensin- degrading enzyme endopeptidase 24-16 in primary cultures of neurons , 1990, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[53] C. Hackenbrock,et al. The random collision model and a critical assessment of diffusion and collision in mitochondrial electron transport , 1986, Journal of bioenergetics and biomembranes.
[54] J P Vincent,et al. Purification and characterization of a novel neurotensin-degrading peptidase from rat brain synaptic membranes. , 1986, The Journal of biological chemistry.