Killing tumor-associated bacteria with a liposomal antibiotic generates neoantigens that induce anti-tumor immune responses.
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Y. He | Leaf Huang | M. Foote | Xuefei Zhou | Wantong Song | A. Anselmo | G. Huang | A. Hamy | C. Le Bihan-Benjamin | Yun Liu | Janelle C. Arthur | Yung-Yi Cheng | P. Armistead | J. Ting | Kunyu Qiu | M. Z. Miao | Kuo-Hsiung Lee | Juliane Nguyen | Oliver Artz | Benoît Rousseau | Elise Dumas | Menglin Wang | Philippe Bousquet | Ava M. Vargason | Fabien Reyal | Lin Lin | Yu Zhang | Hang Su | Ines Khati | Yue Sun | Marc Hilmi | Jianfeng Guo
[1] J. Wargo,et al. Targeting the gut and tumor microbiota in cancer , 2022, Nature Medicine.
[2] Y. Taur,et al. Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy , 2022, Nature Medicine.
[3] Mengwei Xiao,et al. Roseburia intestinalis: A Beneficial Gut Organism From the Discoveries in Genus and Species , 2021, Frontiers in Cellular and Infection Microbiology.
[4] R. Geiger,et al. Metabolic modulation of tumours with engineered bacteria for immunotherapy , 2021, Nature.
[5] A. Nerland,et al. Label-free quantitative proteomic analysis of the oral bacteria Fusobacterium nucleatum and Porphyromonas gingivalis to identify protein features relevant in biofilm formation. , 2021, Anaerobe.
[6] Mingxia Li,et al. Heat shock protein 70 attenuates hypoxia-induced apoptosis of pulmonary microvascular endothelial cells isolated from neonatal rats , 2021, Molecular medicine reports.
[7] M. Dąbrowska,et al. Stability of Metronidazole and Its Complexes with Silver(I) Salts under Various Stress Conditions , 2021, Molecules.
[8] Mei U Wong,et al. Vaxign2: the second generation of the first Web-based vaccine design program using reverse vaccinology and machine learning , 2021, Nucleic Acids Res..
[9] J. Hasty,et al. The microbiome and human cancer , 2021, Science.
[10] E. Ruppin,et al. Identification of bacteria-derived HLA-bound peptides in melanoma , 2021, Nature.
[11] Dominik Żyro,et al. Clinical Application and Efficacy of Silver Drug in Ophthalmology: A Literature Review and New Formulation of EYE Drops with Drug Silver (I) Complex of Metronidazole with Improved Dosage Form , 2021, Biomedicines.
[12] Rebecca L. Holden,et al. Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma , 2021, Nature Medicine.
[13] A. Waisman,et al. A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis , 2021, Science.
[14] Z. Szallasi,et al. Cross-reactivity between tumor MHC class I–restricted antigens and an enterococcal bacteriophage , 2020, Science.
[15] Louise J Newnham,et al. Advances in Anti-Cancer Immunotherapy: Car-T Cell, Checkpoint Inhibitors, Dendritic Cell Vaccines, and Oncolytic Viruses, and Emerging Cellular and Molecular Targets , 2020, Cancers.
[16] Noam Shental,et al. The human tumor microbiome is composed of tumor type–specific intracellular bacteria , 2020, Science.
[17] Effect of CYP3A4 genetic polymorphisms on pharmacokinetics of tinidazole , 2020, Journal of Chinese Pharmaceutical Sciences.
[18] Rob Knight,et al. Microbiome analyses of blood and tissues suggest cancer diagnostic approach , 2020, Nature.
[19] Yingli Wang,et al. Remote loading paclitaxel–doxorubicin prodrug into liposomes for cancer combination therapy , 2020, Acta pharmaceutica Sinica. B.
[20] Ze Lu,et al. Fusobacterium nucleatum promotes epithelial‐mesenchymal transiton through regulation of the lncRNA MIR4435‐2HG/miR‐296‐5p/Akt2/SNAI1 signaling pathway , 2020, The FEBS journal.
[21] Jun Sun,et al. Influence of the Gut Microbiome, Diet, and Environment on Risk of Colorectal Cancer. , 2020, Gastroenterology.
[22] Ze Lu,et al. Fusobacterium nucleatum Caused DNA Damage and Promoted Cell Proliferation by the Ku70/p53 Pathway in Oral Cancer Cells , 2019, DNA and cell biology.
[23] Kenji Mizuguchi,et al. Impact of quality trimming on the efficiency of reads joining and diversity analysis of Illumina paired-end reads in the context of QIIME1 and QIIME2 microbiome analysis frameworks , 2019, BMC Bioinformatics.
[24] U. Eriksson,et al. Microbiota-derived peptide mimics drive lethal inflammatory cardiomyopathy , 2019, Science.
[25] C. Brock,et al. Association of Prior Antibiotic Treatment With Survival and Response to Immune Checkpoint Inhibitor Therapy in Patients With Cancer. , 2019, JAMA oncology.
[26] Christine B. Peterson,et al. Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes , 2019, Cell.
[27] Y. Lee,et al. The Role of Gut Microbiota in Intestinal Inflammation with Respect to Diet and Extrinsic Stressors , 2019, Microorganisms.
[28] Si-Xue Cheng,et al. Phage-guided modulation of the gut microbiota of mouse models of colorectal cancer augments their responses to chemotherapy , 2019, Nature Biomedical Engineering.
[29] Ligeng Xu,et al. Relaxin gene delivery mitigates liver metastasis and synergizes with check point therapy , 2019, Nature Communications.
[30] L. Radko,et al. Silver(I) Complexes of the Pharmaceutical Agents Metronidazole and 4-Hydroxymethylpyridine: Comparison of Cytotoxic Profile for Potential Clinical Application , 2019, Molecules.
[31] Paul D. Boudreau,et al. The human gut bacterial genotoxin colibactin alkylates DNA , 2019, Science.
[32] W. Garrett,et al. Fusobacterium nucleatum — symbiont, opportunist and oncobacterium , 2018, Nature Reviews Microbiology.
[33] Leaf Huang,et al. Trapping of Lipopolysaccharide to Promote Immunotherapy against Colorectal Cancer and Attenuate Liver Metastasis , 2018, Advanced materials.
[34] H. Yao,et al. Fusobacterium and Colorectal Cancer , 2018, Front. Oncol..
[35] Kunyu Qiu,et al. Inorganic nanoparticles and the microbiome , 2018, Nano Research.
[36] Leaf Huang,et al. Synergistic and low adverse effect cancer immunotherapy by immunogenic chemotherapy and locally expressed PD-L1 trap , 2018, Nature Communications.
[37] Jungbae Kim,et al. Selective Killing of Pathogenic Bacteria by Antimicrobial Silver Nanoparticle-Cell Wall Binding Domain Conjugates. , 2018, ACS applied materials & interfaces.
[38] N. Hunter,et al. Metronidazole: an update on metabolism, structure-cytotoxicity and resistance mechanisms. , 2018, The Journal of antimicrobial chemotherapy.
[39] Donna Neuberg,et al. Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer , 2017, Science.
[40] A. Nerland,et al. Quantitative proteomic analysis of extracellular matrix extracted from mono- and dual-species biofilms of Fusobacterium nucleatum and Porphyromonas gingivalis. , 2017, Anaerobe.
[41] J. Li,et al. Pharmacokinetics of the Individual Major Components of Polymyxin B and Colistin in Rats. , 2017, Journal of natural products.
[42] Leaf Huang,et al. Local and transient gene expression primes the liver to resist cancer metastasis , 2016, Science Translational Medicine.
[43] Sergey Tarima,et al. Handling Time-dependent Variables: Antibiotics and Antibiotic Resistance. , 2016, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[44] Paul J. McMurdie,et al. DADA2: High resolution sample inference from Illumina amplicon data , 2016, Nature Methods.
[45] Jonathan L. Linehan,et al. Focused Specificity of Intestinal Th17 Cells towards Commensal Bacterial Antigens , 2014, Nature.
[46] J. Goedert,et al. Human gut microbiome and risk for colorectal cancer. , 2013, Journal of the National Cancer Institute.
[47] M. R. Rubinstein,et al. Fusobacterium nucleatum promotes colorectal carcinogenesis by modulating E-cadherin/β-catenin signaling via its FadA adhesin. , 2013, Cell host & microbe.
[48] K. Katoh,et al. MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability , 2013, Molecular biology and evolution.
[49] Pelin Yilmaz,et al. The SILVA ribosomal RNA gene database project: improved data processing and web-based tools , 2012, Nucleic Acids Res..
[50] S. Prabhu,et al. Silver nanoparticles: mechanism of antimicrobial action, synthesis, medical applications, and toxicity effects , 2012, International Nano Letters.
[51] B. Birren,et al. Genomic analysis identifies association of Fusobacterium with colorectal carcinoma. , 2012, Genome research.
[52] Richard A. Moore,et al. Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma. , 2012, Genome research.
[53] L. Eckmann,et al. Pyruvate:ferredoxin oxidoreductase and thioredoxin reductase are involved in 5-nitroimidazole activation while flavin metabolism is linked to 5-nitroimidazole resistance in Giardia lamblia. , 2011, The Journal of antimicrobial chemotherapy.
[54] C. Huttenhower,et al. Metagenomic biomarker discovery and explanation , 2011, Genome Biology.
[55] M. Ehlers,et al. Rapid blue light induction of protein interactions in living cells , 2010, Nature Methods.
[56] J. Gordon,et al. Our unindicted coconspirators: human metabolism from a microbial perspective. , 2010, Cell metabolism.
[57] Yongqun He,et al. Vaxign: The First Web-Based Vaccine Design Program for Reverse Vaccinology and Applications for Vaccine Development , 2010, Journal of biomedicine & biotechnology.
[58] William A. Walters,et al. Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample , 2010, Proceedings of the National Academy of Sciences.
[59] William A. Walters,et al. QIIME allows analysis of high-throughput community sequencing data , 2010, Nature Methods.
[60] Paramvir S. Dehal,et al. FastTree 2 – Approximately Maximum-Likelihood Trees for Large Alignments , 2010, PloS one.
[61] L. Cantley,et al. Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation , 2009, Science.
[62] H. Clevers,et al. Single Lgr5 stem cells build cryptvillus structures in vitro without a mesenchymal niche , 2009, Nature.
[63] T. Thurnheer,et al. Gingival crevice microbiota from Chinese patients with gingivitis or necrotizing ulcerative gingivitis. , 2004, European journal of oral sciences.
[64] C. Tournay,et al. Efficient detection and immunomagnetic sorting of specific T cells using multimers of MHC class I and peptide with reduced CD8 binding , 2000, Nature Medicine.
[65] Y. Matsumura,et al. Clinicopathologic and immunohistochemical study of early colorectal cancer with liver metastases , 1999, Journal of Gastroenterology.