Evaluating a therapeutic window for precision medicine by integrating genomic profiles and p53 network dynamics

[1]  Chae Young Hwang,et al.  Systems analysis identifies endothelin 1 axis blockade for enhancing the anti-tumor effect of multikinase inhibitor , 2021, Cancer Gene Therapy.

[2]  C. Bellera,et al.  Optimal biological dose: a systematic review in cancer phase I clinical trials , 2021, BMC cancer.

[3]  Richard W Peck,et al.  Precision Dosing: An Industry Perspective , 2020, Clinical pharmacology and therapeutics.

[4]  D. Peeper,et al.  Rational Cancer Treatment Combinations: An Urgent Clinical Need. , 2020, Molecular cell.

[5]  Soo-Youl Kim,et al.  The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in KRAS-Driven Lung Cancer , 2020, Cancers.

[6]  Kwang-Hyun Cho,et al.  Feedback analysis identifies a combination target for overcoming adaptive resistance to targeted cancer therapy , 2020, Oncogene.

[7]  W. Lee-Kwon,et al.  The evolving role of TonEBP as an immunometabolic stress protein , 2020, Nature Reviews Nephrology.

[8]  J. Cheong,et al.  Gastric cancer depends on aldehyde dehydrogenase 3A1 for fatty acid oxidation , 2019, Scientific Reports.

[9]  S. Gorski,et al.  Molecular Mechanisms Underlying Autophagy-Mediated Treatment Resistance in Cancer , 2019, Cancers.

[10]  Neil Vasan,et al.  A view on drug resistance in cancer , 2019, Nature.

[11]  Yingbo Ma,et al.  Autophagy: A novel mechanism of chemoresistance in cancers. , 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[12]  Robert M. Vogel,et al.  Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen , 2019, Nature Communications.

[13]  Wen-Tao Ma,et al.  The Role of Monocytes and Macrophages in Autoimmune Diseases: A Comprehensive Review , 2019, Front. Immunol..

[14]  H. Krämer,et al.  Autophagy Keeps the Balance in Tissue Homeostasis. , 2019, Developmental cell.

[15]  Kwang-Hyun Cho,et al.  Systems analysis identifies potential target genes to overcome cetuximab resistance in colorectal cancer cells , 2019, The FEBS journal.

[16]  M. Bulyk,et al.  The multiple mechanisms that regulate p53 activity and cell fate , 2019, Nature Reviews Molecular Cell Biology.

[17]  J. Aramburu,et al.  Regulation of Inflammatory Functions of Macrophages and T Lymphocytes by NFAT5 , 2019, Front. Immunol..

[18]  Wan-Uk Kim,et al.  Role of NFAT5 in the Immune System and Pathogenesis of Autoimmune Diseases , 2019, Front. Immunol..

[19]  N. Kim,et al.  Loss of SLC25A11 causes suppression of NSCLC and melanoma tumor formation , 2019, EBioMedicine.

[20]  Soo‐Youl Kim.  Targeting cancer energy metabolism: a potential systemic cure for cancer , 2019, Archives of Pharmacal Research.

[21]  Soo-Youl Kim,et al.  Targeting Mitochondrial Oxidative Phosphorylation Abrogated Irinotecan Resistance in NSCLC , 2018, Scientific Reports.

[22]  J. Redondo,et al.  Macrophage-specific MHCII expression is regulated by a remote Ciita enhancer controlled by NFAT5 , 2018, The Journal of experimental medicine.

[23]  Anthony J. Payne,et al.  Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps , 2018, Nature Genetics.

[24]  M. Stratton,et al.  The landscape of somatic mutation in normal colorectal epithelial cells , 2018, Nature.

[25]  I. Tannock,et al.  The paradox of precision medicine , 2018, Nature Reviews Clinical Oncology.

[26]  Steven J. M. Jones,et al.  Comprehensive Characterization of Cancer Driver Genes and Mutations , 2018, Cell.

[27]  Soo-Jin Jeong,et al.  Phytochemical allylguaiacol exerts a neuroprotective effect on hippocampal cells and ameliorates scopolamine-induced memory impairment in mice , 2018, Behavioural Brain Research.

[28]  K. Myung,et al.  Tonicity-responsive enhancer-binding protein promotes hepatocellular carcinogenesis, recurrence and metastasis , 2018, Gut.

[29]  I. McInnes,et al.  Driving chronicity in rheumatoid arthritis: perpetuating role of myeloid cells , 2018, Clinical and experimental immunology.

[30]  R. Pádua,et al.  A rapid simultaneous determination of methylxanthines and proanthocyanidins in Brazilian guaraná (Paullinia cupana Kunth.). , 2018, Food chemistry.

[31]  Elsje G. Otten,et al.  mTORC1 as the main gateway to autophagy , 2017, Essays in biochemistry.

[32]  D. Goldstein,et al.  Drug development in the era of precision medicine , 2017, Nature Reviews Drug Discovery.

[33]  Soo-Youl Kim,et al.  Cancer Energy Metabolism: Shutting Power off Cancer Factory , 2017, Biomolecules & therapeutics.

[34]  Kwang-Hyun Cho,et al.  Network dynamics-based cancer panel stratification for systemic prediction of anticancer drug response , 2017, Nature Communications.

[35]  J. Hong,et al.  Antarctic Krill Oil Diet Protects against Lipopolysaccharide-Induced Oxidative Stress, Neuroinflammation and Cognitive Impairment , 2017, International journal of molecular sciences.

[36]  M. P. Dobhal,et al.  In Vitro Antioxidant Activity of Selected Medicinal Plants Reported in Ancient Ayurveda Traditions , 2017 .

[37]  A. Parsa,et al.  Tonicity-Responsive Enhancer-Binding Protein Mediates Hyperglycemia-Induced Inflammation and Vascular and Renal Injury. , 2017, Journal of the American Society of Nephrology : JASN.

[38]  Jun Ki Kim,et al.  Fluorescent cell-selective ablation using an adaptive photodynamic method. , 2017, Chemical communications.

[39]  Jong-Hee Chang,et al.  Regulation of bioenergetics through dual inhibition of aldehyde dehydrogenase and mitochondrial complex I suppresses glioblastoma tumorspheres , 2017, Neuro-oncology.

[40]  Evan O. Paull,et al.  Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling , 2017, Nature Communications.

[41]  Elizabeth H. Williams,et al.  GRcalculator: an online tool for calculating and mining dose–response data , 2017, BMC Cancer.

[42]  Hyeun-kyoo Shin,et al.  Simultaneous Quantification of Eight Marker Compounds in Yongdamsagan-Tang Using a High-Performance Liquid Chromatography Equipped with Photodiode Array Detector. , 2017, Journal of chromatographic science.

[43]  R. Saunders,et al.  A new Infrared Atmospheric Sounding Interferometer channel selection and assessment of its impact on Met Office NWP forecasts , 2017, Advances in Atmospheric Sciences.

[44]  S. Miyano,et al.  A comprehensive characterization of cis-acting splicing-associated variants in human cancer , 2017, bioRxiv.

[45]  Giulia Menichetti,et al.  Network integration of multi-tumour omics data suggests novel targeting strategies , 2017, bioRxiv.

[46]  Jian Ni,et al.  Radix Bupleuri: A Review of Traditional Uses, Botany, Phytochemistry, Pharmacology, and Toxicology , 2017, BioMed research international.

[47]  E. White,et al.  Autophagy and Tumor Metabolism. , 2017, Cell metabolism.

[48]  A. Azadmehr,et al.  The Anti-Parkinsonism Effects of KATP Channel Blockade in the 6-Hydroxydopamine-Induced Animal Model: The Role of Oxidative Stress , 2017, Basic and clinical neuroscience.

[49]  T. Yun,et al.  The Importance of Dendritic Cells in Maintaining Immune Tolerance , 2017, The Journal of Immunology.

[50]  D. Hwang,et al.  Transcription factor NFAT5 promotes macrophage survival in rheumatoid arthritis , 2017, The Journal of clinical investigation.

[51]  D. Hong,et al.  Aldehyde dehydrogenase is used by cancer cells for energy metabolism , 2016, Experimental & Molecular Medicine.

[52]  Soo-Jin Jeong,et al.  Apigetrin from Scutellaria baicalensis Georgi Inhibits Neuroinflammation in BV-2 Microglia and Exerts Neuroprotective Effect in HT22 Hippocampal Cells. , 2016, Journal of medicinal food.

[53]  S. Seok,et al.  GM-CSF Grown Bone Marrow Derived Cells Are Composed of Phenotypically Different Dendritic Cells and Macrophages , 2016, Molecules and cells.

[54]  Jung Hun Lee,et al.  Effects of Ukgansan Pharmacopuncture at GB20 on Cognitive Impariment Induced by Focal Brain Injury in Rats , 2016 .

[55]  N. Iwata,et al.  Yokukansan in the Treatment of Behavioral and Psychological Symptoms of Dementia: An Updated Meta-Analysis of Randomized Controlled Trials. , 2016, Journal of Alzheimer's disease : JAD.

[56]  H. Perlman,et al.  The inflammatory role of phagocyte apoptotic pathways in rheumatic diseases , 2016, Nature Reviews Rheumatology.

[57]  Soo-Jin Jeong,et al.  Quantitative Analysis of Psoralea corylifolia Linne and its Neuroprotective and Anti-Neuroinflammatory Effects in HT22 Hippocampal Cells and BV-2 Microglia , 2016, Molecules.

[58]  Soo-Youl Kim,et al.  Aldehyde dehydrogenase inhibition combined with phenformin treatment reversed NSCLC through ATP depletion , 2016, Oncotarget.

[59]  J. Lee,et al.  TonEBP suppresses IL-10-mediated immunomodulation , 2016, Scientific Reports.

[60]  Y. Seo,et al.  LPS-induced NFκB enhanceosome requires TonEBP/NFAT5 without DNA binding , 2016, Scientific Reports.

[61]  P. Sorger,et al.  Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs , 2016, Nature Methods.

[62]  K. Dong,et al.  Anti-inflammatory, analgesic and antioxidant activities of 3,4-oxo-isopropylidene-shikimic acid , 2016, Pharmaceutical biology.

[63]  Po-Wei Tsai,et al.  Anti-inflammatory and Antinociceptive Constituents of Atractylodes japonica Koidzumi. , 2016, Journal of agricultural and food chemistry.

[64]  W. Wilcox,et al.  Changing paradigm of cancer therapy: precision medicine by next-generation sequencing , 2016, Cancer biology & medicine.

[65]  T. Konishi,et al.  The role of the seven crude drug components in the sleep-promoting effect of Yokukansan. , 2016, Journal of ethnopharmacology.

[66]  R. Gan,et al.  Antioxidant Phytochemicals for the Prevention and Treatment of Chronic Diseases , 2015, Molecules.

[67]  L. Taams,et al.  The Interplay Between Monocytes/Macrophages and CD4+ T Cell Subsets in Rheumatoid Arthritis , 2015, Front. Immunol..

[68]  Hyeun-kyoo Shin,et al.  Quality Assessment of Ojeok-San, a Traditional Herbal Formula, Using High-Performance Liquid Chromatography Combined with Chemometric Analysis , 2015, Journal of analytical methods in chemistry.

[69]  H. Kim,et al.  Quantitative analysis of marker compounds in Angelica gigas, Angelica sinensis, and Angelica acutiloba by HPLC/DAD. , 2015, Chemical & pharmaceutical bulletin.

[70]  P. Chakravarty,et al.  GM-CSF Mouse Bone Marrow Cultures Comprise a Heterogeneous Population of CD11c(+)MHCII(+) Macrophages and Dendritic Cells. , 2015, Immunity.

[71]  Soo-Jin Jeong,et al.  Anti-adipogenic and antioxidant effects of the traditional Korean herbal formula Samchulgeonbi-tang: an in vitro study. , 2015, International journal of clinical and experimental medicine.

[72]  Hanhong Bae,et al.  Significance of Antioxidant Potential of Plants and its Relevance to Therapeutic Applications , 2015, International journal of biological sciences.

[73]  M. Dougados,et al.  Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force , 2015 .

[74]  Seung-Yeon Cho,et al.  Herbal medicine treatment for drug-induced parkinsonism. , 2015, Journal of alternative and complementary medicine.

[75]  K. Humphries,et al.  Selective inhibition of deactivated mitochondrial complex I by biguanides. , 2015, Biochemistry.

[76]  Karen A. Ryall,et al.  Systems biology approaches for advancing the discovery of effective drug combinations , 2015, Journal of Cheminformatics.

[77]  Paul A Clemons,et al.  Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map. , 2015, Cancer discovery.

[78]  W. Neuhofer,et al.  Generation of a conditional knockout allele for the NFAT5 gene in mice , 2015, Front. Physiol..

[79]  Kwang-Hyun Cho,et al.  The switching role of β-adrenergic receptor signalling in cell survival or death decision of cardiomyocytes , 2014, Nature Communications.

[80]  Soo-Jin Jeong,et al.  Antioxidant and Antiadipogenic Activities of Galkeun-Tang, a Traditional Korean Herbal Formula , 2014, Evidence-based complementary and alternative medicine : eCAM.

[81]  Wenyuan Liu,et al.  Chemical profile of the active fraction of Yi-Gan San by HPLC-DAD-Q-TOF-MS and its neuroprotective effect against glutamate-induced cytotoxicity. , 2014, Chinese journal of natural medicines.

[82]  Per Sunnerhagen,et al.  Flemingins G-O, cytotoxic and antioxidant constituents of the leaves of Flemingia grahamiana. , 2014, Journal of natural products.

[83]  R. Bernards,et al.  Drug resistance to targeted therapies: Déjà vu all over again , 2014, Molecular oncology.

[84]  Florent Ginhoux,et al.  Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny , 2014, Nature Reviews Immunology.

[85]  Jiwoo Lee,et al.  Simultaneous determination of 11 major components in Palmul-tang by HPLC-DAD and LC-MS-MS. , 2014, Journal of chromatographic science.

[86]  T. Lawrence,et al.  Dendritic cell maturation: functional specialization through signaling specificity and transcriptional programming , 2014, The EMBO journal.

[87]  J. Verweij,et al.  Determining the optimal dose in the development of anticancer agents , 2014, Nature Reviews Clinical Oncology.

[88]  Chung Pin Liang,et al.  In Vitro Antioxidant Activities, Free Radical Scavenging Capacity, and Tyrosinase Inhibitory of Flavonoid Compounds and Ferulic Acid from Spiranthes sinensis (Pers.) Ames , 2014, Molecules.

[89]  F. Tacchini-Cottier,et al.  Trapping of naive lymphocytes triggers rapid growth and remodeling of the fibroblast network in reactive murine lymph nodes , 2013, Proceedings of the National Academy of Sciences.

[90]  Gail E. Bingham,et al.  Noise performance of the CrIS instrument , 2013 .

[91]  Y. Kase,et al.  Simultaneous quantitative analyses of indole and oxindole alkaloids of Uncaria Hook in rat plasma and brain after oral administration of the traditional Japanese medicine Yokukansan using high-performance liquid chromatography with tandem mass spectrometry. , 2013, Biomedical chromatography : BMC.

[92]  Wenyuan Liu,et al.  Analysis of the traditional medicine YiGan San by the fragmentation patterns of cadambine indole alkaloids using HPLC coupled with high-resolution MS. , 2013, Journal of separation science.

[93]  S. Yamawaki,et al.  Yokukansan treatment of chronic renal failure patients receiving hemodialysis, with behavioral and psychological symptoms of dementia: an open-label study. , 2013, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

[94]  Alexander Hoffmann,et al.  The Dynamics of Signaling as a Pharmacological Target , 2013, Cell.

[95]  Z. Huang,et al.  Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment , 2013, Cell Death and Disease.

[96]  P. Johnston,et al.  Cancer drug resistance: an evolving paradigm , 2013, Nature Reviews Cancer.

[97]  Joshua M. Stuart,et al.  The Cancer Genome Atlas Pan-Cancer analysis project , 2013, Nature Genetics.

[98]  V. Kuchroo,et al.  IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39 , 2013, Nature Immunology.

[99]  G. Azizi,et al.  Th17 Cells in Immunopathogenesis and treatment of rheumatoid arthritis , 2013, International journal of rheumatic diseases.

[100]  Christopher D. Barnet,et al.  Methodology and Information Content of the NOAA NESDIS Operational Channel Selection for the Cross-Track Infrared Sounder (CrIS) , 2013, IEEE Transactions on Geoscience and Remote Sensing.

[101]  N. Yosef,et al.  Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells , 2013, Nature.

[102]  G. Lahav,et al.  Encoding and Decoding Cellular Information through Signaling Dynamics , 2013, Cell.

[103]  K. O'Byrne,et al.  Generation and Characterisation of Cisplatin-Resistant Non-Small Cell Lung Cancer Cell Lines Displaying a Stem-Like Signature , 2013, PloS one.

[104]  A. Gibofsky,et al.  Overview of epidemiology, pathophysiology, and diagnosis of rheumatoid arthritis. , 2012, The American journal of managed care.

[105]  D. Becker.  Basic and clinical pharmacology of autonomic drugs. , 2012, Anesthesia progress.

[106]  Sridhar Ramaswamy,et al.  Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells , 2012, Nucleic Acids Res..

[107]  Kwang-Hyun Cho,et al.  Attractor Landscape Analysis Reveals Feedback Loops in the p53 Network That Control the Cellular Response to DNA Damage , 2012, Science Signaling.

[108]  B. Faltas.  Cornering metastases: therapeutic targeting of circulating tumor cells and stem cells , 2012, Front. Oncol..

[109]  R. Berne,et al.  NFAT5 expression in bone marrow-derived cells enhances atherosclerosis and drives macrophage migration , 2012, Front. Physio..

[110]  Vindhya Koppaka,et al.  Aldehyde Dehydrogenase Inhibitors: a Comprehensive Review of the Pharmacology, Mechanism of Action, Substrate Specificity, and Clinical Application , 2012, Pharmacological Reviews.

[111]  K. Nagata,et al.  Effects of yokukansan on behavioral and psychological symptoms of vascular dementia: an open-label trial. , 2012, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[112]  M. Sasaki,et al.  Effect of yokukansan on psychophysiological insomnia evaluated using cyclic alternating pattern as an objective marker of sleep instability , 2012 .

[113]  V. Polunovsky,et al.  Translational control of cell fate: From integration of environmental signals to breaching anticancer defense , 2012, Cell cycle.

[114]  Adam A. Margolin,et al.  The Cancer Cell Line Encyclopedia enables predictive modeling of anticancer drug sensitivity , 2012, Nature.

[115]  J. Aramburu,et al.  Gene expression induced by Toll-like receptors in macrophages requires the transcription factor NFAT5 , 2012, The Journal of experimental medicine.

[116]  M. Lipp,et al.  Coordinated Regulation of Lymph Node Vascular–Stromal Growth First by CD11c+ Cells and Then by T and B Cells , 2011, The Journal of Immunology.

[117]  D. Kerr,et al.  Predictive biomarkers: a paradigm shift towards personalized cancer medicine , 2011, Nature Reviews Clinical Oncology.

[118]  D. Hwang,et al.  NF-AT5 is a critical regulator of inflammatory arthritis. , 2011, Arthritis and rheumatism.

[119]  D. Krishnaiah,et al.  A review of the antioxidant potential of medicinal plant species , 2011 .

[120]  C. Arteaga,et al.  Resistance to HER2-directed antibodies and tyrosine kinase inhibitors , 2011, Cancer biology & therapy.

[121]  S. Ho,et al.  TonEBP stimulates multiple cellular pathways for adaptation to hypertonic stress: organic osmolyte-dependent and -independent pathways. , 2011, AJP - Renal Physiology.

[122]  A. Wen,et al.  Autophagy is a therapeutic target in anticancer drug resistance. , 2010, Biochimica et biophysica acta.

[123]  K. Isselbacher,et al.  Isolation of circulating tumor cells using a microvortex-generating herringbone-chip , 2010, Proceedings of the National Academy of Sciences.

[124]  Wen-Chin Yang,et al.  Anti-Hyperglycemic Properties of Crude Extract and Triterpenes from Poria cocos , 2010, Evidence-based complementary and alternative medicine : eCAM.

[125]  Klaus Pantel,et al.  Circulating tumour cells in cancer patients: challenges and perspectives. , 2010, Trends in molecular medicine.

[126]  W. Gianni,et al.  Circulating tumor cells in cancer therapy: are we off target? , 2010, Current Cancer Drug Targets.

[127]  Uwe Völker,et al.  New loci associated with kidney function and chronic kidney disease , 2010, Nature Genetics.

[128]  D. Hailey,et al.  Autophagy termination and lysosome reformation regulated by mTOR , 2010, Nature.

[129]  L. Ellis,et al.  Resistance to Targeted Therapies: Refining Anticancer Therapy in the Era of Molecular Oncology , 2009, Clinical Cancer Research.

[130]  J. Isaacs,et al.  Tumour necrosis factor alpha blockade impairs dendritic cell survival and function in rheumatoid arthritis , 2009, Annals of the rheumatic diseases.

[131]  J. Moreau,et al.  Myeloid dendritic cells correlate with clinical response whereas plasmacytoid dendritic cells impact autoantibody development in rheumatoid arthritis patients treated with infliximab , 2009, Arthritis research & therapy.

[132]  Richard Durbin,et al.  Sequence analysis Fast and accurate short read alignment with Burrows – Wheeler transform , 2009 .

[133]  A. Mcnally,et al.  The assimilation of Infrared Atmospheric Sounding Interferometer radiances at ECMWF , 2009 .

[134]  Min Ye,et al.  Chemical analysis of the Chinese herbal medicine Gan-Cao (licorice). , 2009, Journal of chromatography. A.

[135]  H. Yoo,et al.  Simultaneous determination of phenolic acids and phthalide compounds by liquid chromatography for quality assessment of Rhizoma cnidii. , 2009, Journal of AOAC International.

[136]  A. Hopkins.  Network pharmacology: the next paradigm in drug discovery. , 2008, Nature chemical biology.

[137]  P. Tak,et al.  Rheumatoid arthritis synovium contains two subsets of CD83-DC-LAMP- dendritic cells with distinct cytokine profiles. , 2008, The American journal of pathology.

[138]  M. Furuya,et al.  Yi-gan san for the treatment of neuroleptic-induced tardive dyskinesia: An open-label study , 2008, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[139]  S. Digumarthy,et al.  Isolation of rare circulating tumour cells in cancer patients by microchip technology , 2007, Nature.

[140]  Michael H Weisman,et al.  New therapies for treatment of rheumatoid arthritis , 2007, The Lancet.

[141]  N. Mizushima,et al.  Autophagy: process and function. , 2007, Genes & development.

[142]  Andrew Collard,et al.  Selection of IASI channels for use in numerical weather prediction , 2007 .

[143]  A. Barabasi,et al.  Drug—target network , 2007, Nature Biotechnology.

[144]  B. Hinz,et al.  Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells , 2007, Nature Immunology.

[145]  Siyang Zheng,et al.  Membrane microfilter device for selective capture, electrolysis and genomic analysis of human circulating tumor cells. , 2007, Journal of chromatography. A.

[146]  P. Paterlini-Bréchot,et al.  Circulating tumor cells (CTC) detection: clinical impact and future directions. , 2007, Cancer letters.

[147]  Philip S Low,et al.  In vivo quantitation of rare circulating tumor cells by multiphoton intravital flow cytometry , 2007, Proceedings of the National Academy of Sciences.

[148]  A. Koch.  The pathogenesis of rheumatoid arthritis. , 2007, American journal of orthopedics.

[149]  Brigitte Rack,et al.  Detection of Circulating Tumor Cells in Peripheral Blood of Patients with Metastatic Breast Cancer: A Validation Study of the CellSearch System , 2007, Clinical Cancer Research.

[150]  K. Wiman,et al.  Strategies for therapeutic targeting of the p53 pathway in cancer , 2006, Cell Death and Differentiation.

[151]  Kwang-Hyun Cho,et al.  The influence of the signal dynamics of activated form of IKK on NF‐κB and anti‐apoptotic gene expressions: A systems biology approach , 2006, FEBS letters.

[152]  B Combe,et al.  EULAR recommendations for the management of early arthritis: report of a task force of the European Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT) , 2006, Annals of the rheumatic diseases.

[153]  P. Tak,et al.  Enumeration and phenotypical analysis of distinct dendritic cell subsets in psoriatic arthritis and rheumatoid arthritis , 2005, Arthritis research & therapy.

[154]  Randall L. Lindquist,et al.  Visualizing dendritic cell networks in vivo , 2004, Nature Immunology.

[155]  A. Iwasaki,et al.  Toll-like receptor control of the adaptive immune responses , 2004, Nature Immunology.

[156]  S. Ho,et al.  NFAT5/TonEBP mutant mice define osmotic stress as a critical feature of the lymphoid microenvironment. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[157]  Takeshi Norimatsu,et al.  Encoding and Decoding , 2016 .

[158]  Jong-sang Park,et al.  Suppression of collagen-induced arthritis by single administration of poly(lactic-co-glycolic acid) nanoparticles entrapping type II collagen: a novel treatment strategy for induction of oral tolerance. , 2002, Arthritis and rheumatism.

[159]  Florence Rabier,et al.  Channel selection methods for Infrared Atmospheric Sounding Interferometer radiances , 2002 .

[160]  J. Kalden,et al.  The balance of Th1/Th2 cytokines in rheumatoid arthritis. , 2001, Best practice & research. Clinical rheumatology.

[161]  A. Jaeschke,et al.  Mammalian TOR: A Homeostatic ATP Sensor , 2001, Science.

[162]  M. Fussenegger,et al.  A mathematical model of caspase function in apoptosis , 2000, Nature Biotechnology.

[163]  A. Rao,et al.  NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and Jun. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[164]  S. K. Woo,et al.  Tonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicity. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[165]  A. Billiau,et al.  Anti‐IL‐12 antibody prevents the development and progression of collagen‐induced arthritis in IFN‐γ receptor‐deficient mice , 1998, European journal of immunology.

[166]  W. Lieberthal,et al.  Graded ATP depletion can cause necrosis or apoptosis of cultured mouse proximal tubular cells. , 1998, American journal of physiology. Renal physiology.

[167]  R. Thomas,et al.  Functional differentiation of dendritic cells in rheumatoid arthritis: role of CD86 in the synovium. , 1996, Journal of immunology.

[168]  G. Singh,et al.  Accumulation of human promyelocytic leukemic (HL-60) cells at two energetic cell cycle checkpoints. , 1995, Cancer research.

[169]  L. Davis,et al.  Rheumatoid synovium is enriched in mature antigen-presenting dendritic cells. , 1994, Journal of immunology.

[170]  M. Dixon,et al.  TITAN: Thunderstorm Identification, Tracking, Analysis, and Nowcasting—A Radar-based Methodology , 1993 .

[171]  L. Liu,et al.  Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin. , 1988, Cancer research.

[172]  A. Blanco,et al.  In vitro inhibition by gossypol of oxidoreductases from human tissues. , 1986, Biochemical pharmacology.

[173]  Shuang Jiang,et al.  In Vitro Antioxidant activities and anti-diabetic effect of a polysaccharide from Schisandra sphenanthera in rats with type 2 diabetes. , 2017, International journal of biological macromolecules.

[174]  Nitesh Kumar,et al.  Insulin Protects against Brain Oxidative Stress with an Apparent Effect on Episodic Memory in Doxorubicin-Induced Cognitive Dysfunction in Wistar Rats. , 2017, Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer.

[175]  J. Horiguchi.  [Clinical usage of Yi-gan san-schizophrenia, borderline personality disorder, dyskinesia etc-]. , 2012, Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica.

[176]  R. Toes,et al.  Dendritic cells and their potential implication in pathology and treatment of rheumatoid arthritis. , 2009, Handbook of experimental pharmacology.

[177]  Shalin H. Naik,et al.  Steady-state and inflammatory dendritic-cell development , 2007, Nature Reviews Immunology.

[178]  Kwang-Hyun Cho,et al.  Microarray data clustering based on temporal variation: FCV with TSD preclustering. , 2003, Applied bioinformatics.

[179]  K M Ardeshna,et al.  The PI3 kinase, p38 SAP kinase, and NF-kappaB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte-derived dendritic cells. , 2000, Blood.

[180]  A. Sutter,et al.  Immunophenotypical and functional characterization of bone marrow derived dendritic cells. , 1995, Advances in experimental medicine and biology.

[181]  T. Chou,et al.  Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. , 1984, Advances in enzyme regulation.

[182]  C. Werning.  [Rheumatoid arthritis]. , 1983, Medizinische Monatsschrift fur Pharmazeuten.

[183]  P. Ricciardi-Castagnoli,et al.  Brief Definitive Report Dendritic Cell Survival and Maturation Are Regulated by Different Signaling Pathways , 2022 .