Caudate atrophy on MRI is a characteristic feature of FTLD‐FUS

Background and purpose:  Frontotemporal lobar degeneration (FTLD) can be subdivided into those in which the abnormal protein is tau (FTLD‐TAU), the TAR DNA binding protein 43 (FTLD‐TDP) and the fused in sarcoma protein (FTLD‐FUS). We have observed severe caudate atrophy at autopsy in FTLD‐FUS, and hence, we aimed to determine whether caudate atrophy on MRI is a feature that can distinguish FTLD‐FUS from FTLD‐TDP and FTLD‐TAU.

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