Ultrastructural Properties in Cortical Bone Vary Greatly in Two Inbred Strains of Mice as Assessed by Synchrotron Light Based Micro‐ and Nano‐CT

Nondestructive SR‐based μCT and nano‐CT methods have been designed for 3D quantification and morphometric analysis of ultrastructural phenotypes within murine cortical bone, namely the canal network and the osteocyte lacunar system. Results in two different mouse strains, C57BL/6J‐Ghrhrlit/J and C3.B6‐Ghrhrlit/J, showed that the cannular and lacunar morphometry and their bone mechanics were fundamentally different.

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