Membrane potential studies on cholesterol liquid membranes

Abstract The present study concerns formation and characterization of cholesterol liquid membranes. Dowex-50 and cellulose acetate films are used for supporting the liquid membrane. Liquid membrane generation was ascertained by measurement of alterations in the resistivity of the substrate films due to the accumulation of cholesterol moieties in the interfacial region. Membrane potential measurements were carried out to derive ionic transport numbers in the membrane phase for the estimation of permselectivity and fixed charge densities. The variation of these membrane parameters with pH and the concentration of sodium chloride solutions used was also investigated.