Effects of robotic therapy on motor impairment and recovery in chronic stroke.

OBJECTIVE To examine whether robotic therapy can reduce motor impairment and enhance recovery of the hemiparetic arm in persons with chronic stroke. DESIGN Pre-posttest design. SETTING Rehabilitation hospital, outpatient care. PARTICIPANTS Volunteer sample of 20 persons diagnosed with a single, unilateral stroke within the past 1 to 5 years, with persistent hemiparesis. INTERVENTIONS Robotic therapy was provided 3 times weekly for 6 weeks. Subjects able to reach robot targets were randomly assigned to sensorimotor or progressive-resistive robotic therapy groups. Robotic therapy consisted of goal-directed, planar reaching tasks to exercise the hemiparetic shoulder and elbow. MAIN OUTCOME MEASURES The Modified Ashworth Scale, Fugl-Meyer test of upper-extremity function, Motor Status Scale (MSS) score, and Medical Research Council motor power score. RESULTS Evaluations by a single blinded therapist revealed statistically significant gains from admission to discharge (P<.05) on the Fugl-Meyer test, MSS score, and motor power score. Secondary analyses revealed group differences: the progressive-resistive therapy group experienced nonspecific improvements on wrist and hand MSS scores that were not observed in the sensorimotor group. CONCLUSIONS Robotic therapy may complement other treatment approaches by reducing motor impairment in persons with moderate to severe chronic impairments.

[1]  Jacob Cohen Statistical Power Analysis for the Behavioral Sciences , 1969, The SAGE Encyclopedia of Research Design.

[2]  A. Fugl-Meyer,et al.  The post-stroke hemiplegic patient. 1. a method for evaluation of physical performance. , 1975, Scandinavian journal of rehabilitation medicine.

[3]  C. Hofsten,et al.  Observations on the development of reaching for moving objects. , 1979, Journal of experimental child psychology.

[4]  Timothy D. Lee,et al.  Motor Control and Learning: A Behavioral Emphasis , 1982 .

[5]  A. Georgopoulos On reaching. , 1986, Annual review of neuroscience.

[6]  Richard W. Bohannon,et al.  Interrater reliability of a modified Ashworth scale of muscle spasticity. , 1987, Physical therapy.

[7]  P. Lachenbruch Statistical Power Analysis for the Behavioral Sciences (2nd ed.) , 1989 .

[8]  P. Duncan,et al.  Measurement of Motor Recovery After Stroke: Outcome Assessment and Sample Size Requirements , 1992, Stroke.

[9]  N. Miller,et al.  Technique to improve chronic motor deficit after stroke. , 1993, Archives of physical medicine and rehabilitation.

[10]  K. Mauritz,et al.  Repetitive training of isolated movements improves the outcome of motor rehabilitation of the centrally paretic hand , 1995, Journal of the Neurological Sciences.

[11]  A. Karni The acquisition of perceptual and motor skills: a memory system in the adult human cortex. , 1996, Brain research. Cognitive brain research.

[12]  B. Brouwer,et al.  Isokinetic strength training of the hemiparetic knee: effects on function and spasticity. , 1997, Archives of physical medicine and rehabilitation.

[13]  N. Hogan,et al.  The effect of robot-assisted therapy and rehabilitative training on motor recovery following stroke. , 1997, Archives of neurology.

[14]  B. Volpe,et al.  Patients with Stroke Confined to Basal Ganglia Have Diminished Response to Rehabilitation Efforts , 1997, Neurology.

[15]  N. Hogan,et al.  Robot-aided neurorehabilitation. , 1998, IEEE transactions on rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society.

[16]  Leslie G. Ungerleider,et al.  The acquisition of skilled motor performance: fast and slow experience-driven changes in primary motor cortex. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[17]  J. Liepert,et al.  Motor cortex plasticity during constraint-induced movement therapy in stroke patients , 1998, Neuroscience Letters.

[18]  J. H. van der Lee,et al.  Forced use of the upper extremity in chronic stroke patients: results from a single-blind randomized clinical trial. , 1999, Stroke.

[19]  E. Taub,et al.  Effects of constraint-induced movement therapy on patients with chronic motor deficits after stroke: a replication. , 1999, Stroke.

[20]  R. Nudo Recovery after damage to motor cortical areas , 1999, Current Opinion in Neurobiology.

[21]  N. Hogan,et al.  Robot training enhanced motor outcome in patients with stroke maintained over 3 years , 1999, Neurology.

[22]  R. Nudo,et al.  Cortical plasticity after stroke: implications for rehabilitation. , 1999, Revue neurologique.

[23]  N. Hogan,et al.  A novel approach to stroke rehabilitation , 2000, Neurology.

[24]  N. Hogan,et al.  Increasing productivity and quality of care: robot-aided neuro-rehabilitation. , 2000, Journal of rehabilitation research and development.

[25]  H. F. Machiel van der Loos,et al.  Development of robots for rehabilitation therapy: the Palo Alto VA/Stanford experience. , 2000, Journal of rehabilitation research and development.

[26]  J. Bean,et al.  High intensity strength training improves strength and functional performance after stroke. , 2000, American journal of physical medicine & rehabilitation.

[27]  K.,et al.  Reliability of measurements of muscle tone and muscle power in stroke patients. , 2000, Age and ageing.

[28]  W. Rymer,et al.  Understanding and treating arm movement impairment after chronic brain injury: progress with the ARM guide. , 2014, Journal of rehabilitation research and development.

[29]  N. Hogan,et al.  Is robot-aided sensorimotor training in stroke rehabilitation a realistic option? , 2001, Current opinion in neurology.

[30]  S. Black,et al.  Bilateral movement enhances ipsilesional cortical activity in acute stroke: A pilot functional MRI study , 2001, Neurology.

[31]  N. Hogan,et al.  Robot-Aided Neurorehabilitation: From Evidence-Based to Science-Based Rehabilitation , 2002, Topics in stroke rehabilitation.

[32]  N. Hogan,et al.  Assessing the Motor Status Score: A Scale for the Evaluation of Upper Limb Motor Outcomes in Patients after Stroke , 2002, Neurorehabilitation and neural repair.

[33]  J. Carr,et al.  Neurological Rehabilitation: Optimizing Motor Performance , 2003 .

[34]  P. Duncan,et al.  Post-Stroke Rehabilitation , 2004 .