Inflammatory lymphangiogenesis: cellular mediators and functional implications

[1]  L. Ng,et al.  Neutrophils contribute to inflammatory lymphangiogenesis by increasing VEGF-A bioavailability and secreting VEGF-D. , 2013, Blood.

[2]  S. Rose-John,et al.  An analysis of the function and expression of D6 on lymphatic endothelial cells. , 2013, Blood.

[3]  S. Bromley,et al.  Recirculating Memory T Cells Are a Unique Subset of CD4+ T Cells with a Distinct Phenotype and Migratory Pattern , 2013, The Journal of Immunology.

[4]  Michael Sixt,et al.  Interstitial Dendritic Cell Guidance by Haptotactic Chemokine Gradients , 2013, Science.

[5]  V. Engelhard,et al.  Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells. , 2012, Blood.

[6]  V. Shi,et al.  Inflammation‐Driven Dermal Lymphangiogenesis in Atopic Dermatitis is Associated with CD11b+ Macrophage Recruitment and VEGF‐C Up‐regulation in the IL‐4‐Transgenic Mouse Model , 2012, Microcirculation.

[7]  V. Kuchroo,et al.  Podoplanin-Rich Stromal Networks Induce Dendritic Cell Motility via Activation of the C-type Lectin Receptor CLEC-2 , 2012, Immunity.

[8]  G. Koh,et al.  Regulation and implications of inflammatory lymphangiogenesis. , 2012, Trends in immunology.

[9]  J. Abastado,et al.  Expansion of Cortical and Medullary Sinuses Restrains Lymph Node Hypertrophy during Prolonged Inflammation , 2012, The Journal of Immunology.

[10]  A. Blauvelt,et al.  Lymphatic dysfunction impairs antigen-specific immunization, but augments tissue swelling following contact with allergens. , 2012, The Journal of investigative dermatology.

[11]  R. Ransohoff,et al.  D6 facilitates cellular migration and fluid flow to lymph nodes by suppressing lymphatic congestion. , 2011, Blood.

[12]  Limin Liu,et al.  Regulation of T Cell Priming by Lymphoid Stroma , 2011, PloS one.

[13]  P. Nelson,et al.  Fibroblastic Reticular Cells From Lymph Nodes Attenuate T Cell Expansion by Producing Nitric Oxide , 2011, PloS one.

[14]  K. Alitalo,et al.  The lymphatic vasculature in disease , 2011, Nature Medicine.

[15]  Kutlu G. Elpek,et al.  Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodes , 2011, Nature Immunology.

[16]  Lai Guan Ng,et al.  DC mobilization from the skin requires docking to immobilized CCL21 on lymphatic endothelium and intralymphatic crawling , 2011, The Journal of experimental medicine.

[17]  S. Halle,et al.  Afferent lymph–derived T cells and DCs use different chemokine receptor CCR7–dependent routes for entry into the lymph node and intranodal migration , 2011, Nature Immunology.

[18]  S. Lira,et al.  A Critical Role for Dendritic Cells in the Formation of Lymphatic Vessels within Tertiary Lymphoid Structures , 2011, The Journal of Immunology.

[19]  C. Halin,et al.  Tissue inflammation modulates gene expression of lymphatic endothelial cells and dendritic cell migration in a stimulus-dependent manner. , 2011, Blood.

[20]  R. Dana,et al.  Thrombospondin 1 inhibits inflammatory lymphangiogenesis by CD36 ligation on monocytes , 2011, The Journal of experimental medicine.

[21]  S. Werner,et al.  An important role of lymphatic vessel activation in limiting acute inflammation. , 2011, Blood.

[22]  G. Koh,et al.  T lymphocytes negatively regulate lymph node lymphatic vessel formation. , 2011, Immunity.

[23]  Jason G. Cyster,et al.  Lymph node cortical sinus organization and relationship to lymphocyte egress dynamics and antigen exposure , 2010, Proceedings of the National Academy of Sciences.

[24]  D. Jackson,et al.  Inflammation-induced secretion of CCL21 in lymphatic endothelium is a key regulator of integrin-mediated dendritic cell transmigration. , 2010, International immunology.

[25]  K. Alitalo,et al.  Stimulation of lymphangiogenesis via VEGFR-3 inhibits chronic skin inflammation , 2010, The Journal of experimental medicine.

[26]  Takashi Ito,et al.  B Cell-Derived Vascular Endothelial Growth Factor A Promotes Lymphangiogenesis and High Endothelial Venule Expansion in Lymph Nodes , 2010, The Journal of Immunology.

[27]  S. Turley,et al.  Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions , 2010, The Journal of experimental medicine.

[28]  A. Ruddell,et al.  Lymph node–resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation , 2010, The Journal of experimental medicine.

[29]  D. McDonald,et al.  Vascular Biology , Atherosclerosis and Endothelium Biology Steroid-Resistant Lymphatic Remodeling in Chronically Inflamed Mouse Airways , 2010 .

[30]  J. Cyster,et al.  Activated regulatory T cells are the major T cell type emigrating from the skin during a cutaneous immune response in mice. , 2010, The Journal of clinical investigation.

[31]  K. Alitalo,et al.  Lymphangiogenesis: Molecular Mechanisms and Future Promise , 2010, Cell.

[32]  Ying Xu,et al.  Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning , 2009, The Journal of experimental medicine.

[33]  D. Carr,et al.  VEGF-A expression by HSV-1–infected cells drives corneal lymphangiogenesis , 2009, The Journal of experimental medicine.

[34]  S. Wiegand,et al.  Cutting Edge: Lymphatic Vessels, Not Blood Vessels, Primarily Mediate Immune Rejections After Transplantation , 2009, The Journal of Immunology.

[35]  R. Schwendener,et al.  Role of CD11b+ macrophages in intraperitoneal lipopolysaccharide-induced aberrant lymphangiogenesis and lymphatic function in the diaphragm. , 2009, The American journal of pathology.

[36]  E. Schwarz,et al.  Inhibition of lymphangiogenesis and lymphatic drainage via vascular endothelial growth factor receptor 3 blockade increases the severity of inflammation in a mouse model of chronic inflammatory arthritis. , 2009, Arthritis and rheumatism.

[37]  M. Skobe,et al.  Inflamed Lymphatic Endothelium Suppresses Dendritic Cell Maturation and Function via Mac-1/ICAM-1-Dependent Mechanism1 , 2009, The Journal of Immunology.

[38]  K. Alitalo,et al.  Critical role of CD11b+ macrophages and VEGF in inflammatory lymphangiogenesis, antigen clearance, and inflammation resolution. , 2009, Blood.

[39]  M. Shibuya,et al.  M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis , 2009, The Journal of experimental medicine.

[40]  M. Detmar,et al.  Activation of the VEGFR-3 pathway by VEGF-C attenuates UVB-induced edema formation and skin inflammation by promoting lymphangiogenesis. , 2009, The Journal of investigative dermatology.

[41]  G. Koh,et al.  Toll-like receptor 4 in lymphatic endothelial cells contributes to LPS-induced lymphangiogenesis by chemotactic recruitment of macrophages. , 2009, Blood.

[42]  M. Sixt,et al.  Preformed portals facilitate dendritic cell entry into afferent lymphatic vessels , 2009, The Journal of experimental medicine.

[43]  R. Dana,et al.  Transient postoperative vascular endothelial growth factor (VEGF)-neutralisation improves graft survival in corneas with partly regressed inflammatory neovascularisation , 2009, British Journal of Ophthalmology.

[44]  T. Phan,et al.  Cortical sinus probing, S1P1-dependent entry and flow-based capture of egressing T cells , 2008, Nature Immunology.

[45]  E. Ekland,et al.  Fibroblast-Type Reticular Stromal Cells Regulate the Lymph Node Vasculature1 , 2008, The Journal of Immunology.

[46]  Howard Y. Chang,et al.  Deletional Tolerance Mediated by Extrathymic Aire-Expressing Cells , 2008, Science.

[47]  M. Sixt,et al.  Rapid leukocyte migration by integrin-independent flowing and squeezing , 2008, Nature.

[48]  J. Cyster,et al.  S1P1 receptor signaling overrides retention mediated by G alpha i-coupled receptors to promote T cell egress. , 2008, Immunity.

[49]  P. Tak,et al.  Tumour necrosis factor blockade increases lymphangiogenesis in murine and human arthritic joints , 2008, Annals of the rheumatic diseases.

[50]  J. Cyster,et al.  Finding a way out: lymphocyte egress from lymphoid organs , 2007, Nature Immunology.

[51]  E. Schwarz,et al.  Increased lymphangiogenesis in joints of mice with inflammatory arthritis , 2007, Arthritis research & therapy.

[52]  C. Beck,et al.  MRI and Quantification of Draining Lymph Node Function in Inflammatory Arthritis , 2007, Annals of the New York Academy of Sciences.

[53]  M. Detmar,et al.  VEGF-A produced by chronically inflamed tissue induces lymphangiogenesis in draining lymph nodes. , 2007, Blood.

[54]  J. Chung,et al.  Reduction of lymphatic vessels in photodamaged human skin. , 2007, Journal of dermatological science.

[55]  Clare L. Bennett,et al.  Deletional Self-Tolerance to a Melanocyte/Melanoma Antigen Derived from Tyrosinase Is Mediated by a Radio-Resistant Cell in Peripheral and Mesenteric Lymph Nodes1 , 2007, The Journal of Immunology.

[56]  F. Kruse,et al.  Inhibition of Inflammatory Lymphangiogenesis by Integrin α5 Blockade , 2007 .

[57]  M. Skobe,et al.  Lymphotoxin β receptor signaling is required for inflammatory lymphangiogenesis in the thyroid , 2007, Proceedings of the National Academy of Sciences.

[58]  S. Turley,et al.  Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self , 2007, Nature Immunology.

[59]  D. Jackson,et al.  An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium , 2006, The Journal of experimental medicine.

[60]  S. Hirakawa,et al.  Vascular endothelial growth factor-A mediates ultraviolet B-induced impairment of lymphatic vessel function. , 2006, The American journal of pathology.

[61]  S. Liao,et al.  Synchrony of High Endothelial Venules and Lymphatic Vessels Revealed by Immunization1 , 2006, The Journal of Immunology.

[62]  S. Liao,et al.  Lymphoid organ development: from ontogeny to neogenesis , 2006, Nature Immunology.

[63]  F. Aloisi,et al.  Lymphoid neogenesis in chronic inflammatory diseases , 2006, Nature Reviews Immunology.

[64]  Y. Miyachi,et al.  Lymphangiogenesis promotes lens destruction and subsequent lens regeneration in the newt eyeball, and both processes can be accelerated by transplantation of dendritic cells. , 2006, Developmental biology.

[65]  F. Ginhoux,et al.  B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization. , 2006, Immunity.

[66]  D. Kerjaschki,et al.  Lymphatic endothelial progenitor cells contribute to de novo lymphangiogenesis in human renal transplants , 2006, Nature Medicine.

[67]  K. Maruyama,et al.  Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages. , 2005, The Journal of clinical investigation.

[68]  S. Bromley,et al.  Chemokine receptor CCR7 guides T cell exit from peripheral tissues and entry into afferent lymphatics , 2005, Nature Immunology.

[69]  E. Butcher,et al.  Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues , 2005, Nature Immunology.

[70]  Seppo Ylä-Herttuala,et al.  Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation. , 2005, The Journal of clinical investigation.

[71]  Kaisa Koskinen,et al.  CLEVER-1 mediates lymphocyte transmigration through vascular and lymphatic endothelium. , 2004, Blood.

[72]  D. Hicklin,et al.  Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia. , 2004, Blood.

[73]  K. Maruyama,et al.  Inhibition of hemangiogenesis and lymphangiogenesis after normal-risk corneal transplantation by neutralizing VEGF promotes graft survival. , 2004, Investigative ophthalmology & visual science.

[74]  M. Dana,et al.  Vascular endothelial growth factor receptor-3 mediates induction of corneal alloimmunity , 2004, Nature Medicine.

[75]  Jingtai Cao,et al.  VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment. , 2004, The Journal of clinical investigation.

[76]  P. Laakkonen,et al.  Lymphatic neoangiogenesis in human kidney transplants is associated with immunologically active lymphocytic infiltrates. , 2004, Journal of the American Society of Nephrology : JASN.

[77]  R. Gausas,et al.  Proliferation of D2-40-expressing intestinal lymphatic vessels in the lamina propria in inflammatory bowel disease. , 2004, International journal of molecular medicine.

[78]  D. Jackson,et al.  Distribution of lymphatic vessels in normal and arthritic human synovial tissues , 2003, Annals of the rheumatic diseases.

[79]  E. Kaiserling,et al.  Lymphatic vessels in the colonic mucosa in ulcerative colitis. , 2003, Lymphology.

[80]  M. Dana,et al.  Novel expression of vascular endothelial growth factor receptor (VEGFR)-3 and VEGF-C on corneal dendritic cells. , 2003, The American journal of pathology.

[81]  S. Schoppmann,et al.  Increase in podoplanin-expressing intestinal lymphatic vessels in inflammatory bowel disease , 2003, Virchows Archiv.

[82]  A. Logan,et al.  Angiogenesis , 1993, The Lancet.

[83]  K. Maruyama,et al.  Promotion of graft survival by vascular endothelial growth factor a neutralization after high-risk corneal transplantation. , 2008, Archives of ophthalmology.

[84]  F. Kruse,et al.  Inhibition of inflammatory lymphangiogenesis by integrin alpha5 blockade. , 2007, The American journal of pathology.

[85]  C. Ligorio,et al.  Lymphangiogenesis in Crohn’s disease: an immunohistochemical study using monoclonal antibody D2-40 , 2007, Virchows Archiv.

[86]  L. Wilkinson,et al.  Demonstration of lymphatics in human synovial tissue , 2004, Rheumatology International.