An IL-10/DEL-1 axis supports granulopoiesis and survival from sepsis in early life

[1]  G. Hajishengallis,et al.  Inflammatory Modulation of Hematopoiesis: Linking Trained Immunity and Clonal Hematopoiesis with Chronic Disorders. , 2021, Annual review of physiology.

[2]  Meng Li,et al.  Regulatory role of local tissue signal Del-1 in cancer and inflammation: a review , 2021, Cellular & molecular biology letters.

[3]  M. Sperandio,et al.  DHEA Inhibits Leukocyte Recruitment through Regulation of the Integrin Antagonist DEL-1 , 2020, The Journal of Immunology.

[4]  Sang-Bum Hong,et al.  Serum developmental endothelial locus-1 is associated with severity of sepsis in animals and humans , 2019, Scientific Reports.

[5]  G. Hajishengallis,et al.  Hematopoietic progenitor cells as integrative hubs for adaptation to and fine-tuning of inflammation , 2019, Nature Immunology.

[6]  G. Hajishengallis,et al.  DEL-1-Regulated Immune Plasticity and Inflammatory Disorders. , 2019, Trends in molecular medicine.

[7]  Ga-young Lee,et al.  Age-related differences in the bone marrow stem cell niche generate specialized microenvironments for the distinct regulation of normal hematopoietic and leukemia stem cells , 2019, Scientific Reports.

[8]  Nelly Amenyogbe,et al.  A Controlled Mouse Model for Neonatal Polymicrobial Sepsis. , 2019, Journal of visualized experiments : JoVE.

[9]  Eleni Vergadi,et al.  Changes in the incidence and epidemiology of neonatal group B Streptococcal disease over the last two decades in Crete, Greece , 2018, Infectious disease reports.

[10]  L. Joosten,et al.  DEL-1 promotes macrophage efferocytosis and clearance of inflammation , 2018, Nature Immunology.

[11]  L. Joosten,et al.  Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity , 2018, Cell.

[12]  V. Nizet,et al.  Age-Appropriate Functions and Dysfunctions of the Neonatal Neutrophil , 2017, Front. Pediatr..

[13]  G. Hajishengallis,et al.  DEL-1 restrains osteoclastogenesis and inhibits inflammatory bone loss in nonhuman primates , 2015, Science Translational Medicine.

[14]  G. Hajishengallis,et al.  Antagonistic effects of IL-17 and D-resolvins on endothelial Del-1 expression through a GSK-3β-C/EBPβ pathway , 2015, Nature Communications.

[15]  J. Torres,et al.  Interleukin‐10 plays a key role in the modulation of neutrophils recruitment and lung inflammation during infection by Streptococcus pneumoniae , 2015, Immunology.

[16]  Berthold Göttgens,et al.  Functionally Distinct Subsets of Lineage-Biased Multipotent Progenitors Control Blood Production in Normal and Regenerative Conditions. , 2015, Cell stem cell.

[17]  L. Moldawer,et al.  Delayed emergency myelopoiesis following polymicrobial sepsis in neonates , 2015, Innate immunity.

[18]  H. Saito,et al.  A New Cecal Slurry Preparation Protocol with Improved Long-Term Reproducibility for Animal Models of Sepsis , 2014, PloS one.

[19]  D. Frommhold,et al.  RAGE controls leukocyte adhesion in preterm and term infants , 2014, BMC Immunology.

[20]  E. Chavakis,et al.  Developmental endothelial locus-1 (Del-1) is a homeostatic factor in the central nervous system limiting neuroinflammation and demyelination , 2014, Molecular Psychiatry.

[21]  E. Choi,et al.  Deficiency of developmental endothelial locus-1 (Del-1) aggravates bleomycin-induced pulmonary fibrosis in mice. , 2014, Biochemical and biophysical research communications.

[22]  R. Chambers,et al.  The mercurial nature of neutrophils: still an enigma in ARDS? , 2014, American journal of physiology. Lung cellular and molecular physiology.

[23]  C. Tsatsanis,et al.  Akt2 Deficiency Protects from Acute Lung Injury via Alternative Macrophage Activation and miR-146a Induction in Mice , 2014, The Journal of Immunology.

[24]  R. Jotwani,et al.  Expression and Function of the Homeostatic Molecule Del-1 in Endothelial Cells and the Periodontal Tissue , 2013, Clinical & developmental immunology.

[25]  P. Trieu-Cuot,et al.  TLR2-Induced IL-10 Production Impairs Neutrophil Recruitment to Infected Tissues during Neonatal Bacterial Sepsis , 2013, The Journal of Immunology.

[26]  B. Stoll,et al.  Neonatal infectious diseases: evaluation of neonatal sepsis. , 2013, Pediatric clinics of North America.

[27]  D. Frommhold,et al.  Neutrophil and endothelial adhesive function during human fetal ontogeny , 2013, Journal of leukocyte biology.

[28]  S. Bornstein,et al.  Role of the endothelial-derived endogenous anti-inflammatory factor Del-1 in inflammation-mediated adrenal gland dysfunction. , 2013, Endocrinology.

[29]  J. Lévesque,et al.  Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistance , 2012, Nature Medicine.

[30]  S. Mitra,et al.  Granulocyte Colony-stimulating Factor for Preterms with Sepsis and Neutropenia: A Randomized Controlled Trial , 2012, Journal of clinical neonatology.

[31]  Jia-huai Wang,et al.  The RGD finger of Del‐1 is a unique structural feature critical for integrin binding , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[32]  T. Suda,et al.  Extracellular matrix protein tenascin-C is required in the bone marrow microenvironment primed for hematopoietic regeneration. , 2012, Blood.

[33]  Xinli Huang,et al.  Neutrophils in acute lung injury. , 2012, Frontiers in bioscience.

[34]  R. Jotwani,et al.  The leukocyte integrin antagonist Del-1 inhibits IL-17-mediated inflammatory bone loss , 2012, Nature Immunology.

[35]  P. Kubes,et al.  The neutrophil in vascular inflammation , 2011, Nature Medicine.

[36]  N. Hogg,et al.  G-CSF-mediated thrombopoietin release triggers neutrophil motility and mobilization from bone marrow via induction of Cxcr2 ligands. , 2011, Blood.

[37]  O. Soehnlein,et al.  Contribution of Neutrophils to Acute Lung Injury , 2011, Molecular medicine.

[38]  D. Remick,et al.  The pathogenesis of sepsis. , 2011, Annual review of pathology.

[39]  H. Abele,et al.  Phagocytosis and postphagocytic reaction of cord blood and adult blood monocyte after infection with green fluorescent protein‐labeled Escherichia coli and group B Streptococci , 2009, Cytometry. Part B, Clinical cytometry.

[40]  E. Chavakis,et al.  Del-1, an Endogenous Leukocyte-Endothelial Adhesion Inhibitor, Limits Inflammatory Cell Recruitment , 2008, Science.

[41]  L. Moldawer,et al.  Defective innate immunity predisposes murine neonates to poor sepsis outcome but is reversed by TLR agonists. , 2008, Blood.

[42]  L. Moldawer,et al.  INCREASED MORTALITY AND ALTERED IMMUNITY IN NEONATAL SEPSIS PRODUCED BY GENERALIZED PERITONITIS , 2007, Shock.

[43]  Ofer Levy,et al.  Innate immunity of the newborn: basic mechanisms and clinical correlates , 2007, Nature Reviews Immunology.

[44]  L. Kalish,et al.  Innate Immunity of the Human Newborn Is Polarized Toward a High Ratio of IL-6/TNF-α Production In Vitro and In Vivo , 2006, Pediatric Research.

[45]  C. Probst,et al.  LEUKOCYTE-ENDOTHELIAL INTERACTIONS VIA ICAM-1 ARE DETRIMENTAL IN POLYMICROBIAL SEPSIS , 2006, Shock.

[46]  P. Frenette,et al.  Enforced fucosylation of neonatal CD34+ cells generates selectin ligands that enhance the initial interactions with microvessels but not homing to bone marrow. , 2005, Blood.

[47]  K. Malcolm,et al.  Role of the CXCR4/SDF-1 chemokine axis in circulating neutrophil homeostasis. , 2004, Blood.

[48]  O. Levy Impaired Innate Immunity at Birth: Deficiency of Bactericidal/Permeability-Increasing Protein (BPI) in the Neutrophils of Newborns , 2002, Pediatric Research.

[49]  M. Pfaffl,et al.  A new mathematical model for relative quantification in real-time RT-PCR. , 2001, Nucleic acids research.

[50]  R. Carr Neutrophil Production and Function in Newborn Infants , 2000, British journal of haematology.

[51]  Emmanuel Cruz,et al.  The role of anti-tumor necrosis factor-alpha and interleukin-10 in protecting murine neonates from Escherichia coli sepsis. , 2000, Journal of pediatric surgery.

[52]  M. Cairo,et al.  Potential use of granulocyte colony‐stimulating factor and granulocyte‐macrophage colony‐stimulating factor in neonates , 1998, Current opinion in hematology.

[53]  G. Mancuso,et al.  Interleukin-10 protects neonatal mice from lethal group B streptococcal infection , 1996, Infection and immunity.

[54]  A. Finn,et al.  Neutrophil adhesion molecules in term and premature infants: normal or enhanced leucocyte integrins but defective L‐selectin expression and shedding , 1995, Clinical and experimental immunology.

[55]  I. Boll,et al.  A kinetic model of granulocytopoiesis. , 1970, Experimental cell research.

[56]  OUP accepted manuscript , 2022, Stem Cells.

[57]  G. Hajishengallis,et al.  Endogenous modulators of inflammatory cell recruitment. , 2013, Trends in immunology.

[58]  D. Speert,et al.  Human neonatal monocyte-derived macrophages and neutrophils exhibit normal nonopsonic and opsonic receptor-mediated phagocytosis and superoxide anion production. , 1991, Biology of the neonate.

[59]  PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS Ontogenetic regulation of leukocyte recruitment in mouse yolk sac vessels , 2022 .