Antihepatotoxic activity of kulthi (Dolichos biflorus) seed in rats

Hepatotoxicity was developed in rats by administering paracetamol (500 mg/kg, p.o.) for 28 days; either normal diet or diet enriched with Kulthi (D. biflorus) seeds (10 g/kg, p.o.) were administered for further 28 days. The recovery of paracetamol-intoxicated rats, as shown by decrease in serum aminotransferase activities, bilirubin and blood urea levels, was significantly improved in Kulthi group, providing indication of an antihepatotoxic effect of the plant seed.