Distinctive transcriptome alterations of prefrontal pyramidal neurons in schizophrenia and schizoaffective disorder
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Aiqing He | John P. Corradi | George Tseng | Shaowu Tang | David A. Lewis | G. Tseng | J. Corradi | A. Cacace | Shaowu Tang | C. Albright | D. Datta | Aiqing He | Dominique Arion | D. Arion | Robert Zaczek | Dibyadeep Datta | Franklyn Boothe | Angela M. Cacace | Charles F. Albright | R. Zaczek | D. Lewis | Franklyn Boothe
[1] P. Falkai,et al. Articulatory rehearsal in verbal working memory: A possible neurocognitive endophenotype that differentiates between schizophrenia and schizoaffective disorder , 2005, Neuroscience Letters.
[2] David A Lewis,et al. Lamina-specific reductions in dendritic spine density in the prefrontal cortex of subjects with schizophrenia. , 2005, The American journal of psychiatry.
[3] Victor Vostrikov,et al. Pathology of layer V pyramidal neurons in the prefrontal cortex of patients with schizophrenia. , 2004, The American journal of psychiatry.
[4] P. Goldman-Rakic,et al. Neuronal and glial somal size in the prefrontal cortex: a postmortem morphometric study of schizophrenia and Huntington disease. , 1998, Archives of general psychiatry.
[5] Huda Akil,et al. Effect of agonal and postmortem factors on gene expression profile: quality control in microarray analyses of postmortem human brain , 2004, Biological Psychiatry.
[6] E. Banks,et al. De novo mutations in schizophrenia implicate synaptic networks , 2014, Nature.
[7] On altered patterns of brain activation in at-risk adolescents and young adults. , 2013, The American journal of psychiatry.
[8] Daniel R Weinberger,et al. Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study , 2002, Schizophrenia Research.
[9] Stephen J Glatt,et al. Preliminary evidence of ubiquitin proteasome system dysregulation in schizophrenia and bipolar disorder: Convergent pathway analysis findings from two independent samples , 2010, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.
[10] David A. Lewis,et al. Altered Cortical CDC42 Signaling Pathways in Schizophrenia: Implications for Dendritic Spine Deficits , 2010, Biological Psychiatry.
[11] M. Uittenbogaard,et al. The neurogenic basic helix–loop–helix transcription factor NeuroD6 confers tolerance to oxidative stress by triggering an antioxidant response and sustaining the mitochondrial biomass , 2010, ASN neuro.
[12] A. Arnsten,et al. Neuromodulation of Thought: Flexibilities and Vulnerabilities in Prefrontal Cortical Network Synapses , 2012, Neuron.
[13] Yan Lin,et al. Detecting disease-associated genes with confounding variable adjustment and the impact on genomic meta-analysis: With application to major depressive disorder , 2012, BMC Bioinformatics.
[14] J. Pierri,et al. Gene Expression Profiling Reveals Alterations of Specific Metabolic Pathways in Schizophrenia , 2002, The Journal of Neuroscience.
[15] Jia Li,et al. An adaptively weighted statistic for detecting differential gene expression when combining multiple transcriptomic studies , 2011, 1108.3180.
[16] Y. Benjamini,et al. Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .
[17] K. Mirnics,et al. Schizophrenia as a Disorder of Molecular Pathways , 2015, Biological Psychiatry.
[18] D. Arion,et al. Altered expression of regulators of the cortical chloride transporters NKCC1 and KCC2 in schizophrenia. , 2011, Archives of general psychiatry.
[19] Thomas W. Mühleisen,et al. Large recurrent microdeletions associated with schizophrenia , 2008, Nature.
[20] Christopher H Woelk,et al. A combined analysis of microarray gene expression studies of the human prefrontal cortex identifies genes implicated in schizophrenia. , 2012, Journal of psychiatric research.
[21] S. Hirsch,et al. Reduced dendritic spine density on cerebral cortical pyramidal neurons in schizophrenia , 1998, Journal of neurology, neurosurgery, and psychiatry.
[22] T. Hashimoto,et al. Molecular mechanisms contributing to dendritic spine alterations in the prefrontal cortex of subjects with schizophrenia , 2006, Molecular Psychiatry.
[23] D. Datta,et al. Developmental Expression Patterns of GABAA Receptor Subunits in Layer 3 and 5 Pyramidal Cells of Monkey Prefrontal Cortex. , 2015, Cerebral cortex.
[24] R. Myers,et al. Mitochondrial-related gene expression changes are sensitive to agonal-pH state: implications for brain disorders , 2006, Molecular Psychiatry.
[25] Jesse Gillis,et al. Genome-wide expression profiling of schizophrenia using a large combined cohort , 2011, Molecular Psychiatry.
[26] H. M. Morris,et al. NPY mRNA expression in the prefrontal cortex: Selective reduction in the superficial white matter of subjects with schizoaffective disorder , 2009, Schizophrenia Research.
[27] D. Lewis,et al. Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia. , 2000, Archives of general psychiatry.
[28] Jon W. Johnson,et al. Altered markers of tonic inhibition in the dorsolateral prefrontal cortex of subjects with schizophrenia. , 2009, The American journal of psychiatry.
[29] R. Shprintzen,et al. Schizophrenia susceptibility associated with interstitial deletions of chromosome 22q11. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[30] Stephan Heckers,et al. Molecular evidence for mitochondrial dysfunction in bipolar disorder. , 2004, Archives of general psychiatry.
[31] H. M. Morris,et al. Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophrenia , 2008, Molecular Psychiatry.
[32] D. Volk,et al. Alterations in metabotropic glutamate receptor 1α and regulator of G protein signaling 4 in the prefrontal cortex in schizophrenia. , 2010, The American journal of psychiatry.
[33] Jörg Rahnenführer,et al. Robert Gentleman, Vincent Carey, Wolfgang Huber, Rafael Irizarry, Sandrine Dudoit (2005): Bioinformatics and Computational Biology Solutions Using R and Bioconductor , 2009 .
[34] Martine Uittenbogaard,et al. NeuroD6 genomic signature bridging neuronal differentiation to survival via the molecular chaperone network , 2010, Journal of neuroscience research.
[35] Zhuoxin Sun,et al. The Influence of Chronic Exposure to Antipsychotic Medications on Brain Size before and after Tissue Fixation: A Comparison of Haloperidol and Olanzapine in Macaque Monkeys , 2005, Neuropsychopharmacology.
[36] H. Möller,et al. Evidence for a mitochondrial oxidative phosphorylation defect in brains from patients with schizophrenia , 2001, Schizophrenia Research.
[37] A. Sampson,et al. Decreased glutamic acid decarboxylase67 messenger RNA expression in a subset of prefrontal cortical gamma-aminobutyric acid neurons in subjects with schizophrenia. , 2000, Archives of general psychiatry.
[38] K. Mirnics,et al. Infragranular gene expression disturbances in the prefrontal cortex in schizophrenia: Signature of altered neural development? , 2010, Neurobiology of Disease.
[39] D. Lewis,et al. Dendritic spine pathology in schizophrenia , 2013, Neuroscience.
[40] R. Yolken,et al. Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress , 2004, Molecular Psychiatry.
[41] Andrew L. Lemire,et al. Deficient Hippocampal Neuron Expression of Proteasome, Ubiquitin, and Mitochondrial Genes in Multiple Schizophrenia Cohorts , 2005, Biological Psychiatry.
[42] Huda Akil,et al. Systematic changes in gene expression in postmortem human brains associated with tissue pH and terminal medical conditions. , 2004, Human molecular genetics.
[43] R. Myers,et al. Mitochondrial related gene expression changes are sensitive to agonal-pH state , 2006, Molecular Psychiatry.
[44] Paul Pavlidis,et al. Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model , 2008, Nature Genetics.
[45] K. Mirnics,et al. Molecular markers distinguishing supragranular and infragranular layers in the human prefrontal cortex , 2007, The European journal of neuroscience.
[46] C. Correll. Understanding schizoaffective disorder: from psychobiology to psychosocial functioning. , 2010, The Journal of clinical psychiatry.
[47] J. Glausier,et al. Lower Glutamic Acid Decarboxylase 65-kDa Isoform Messenger RNA and Protein Levels in the Prefrontal Cortex in Schizoaffective Disorder but Not Schizophrenia , 2015, Biological Psychiatry.
[48] B. Moghaddam,et al. NMDA Receptor Hypofunction Produces Opposite Effects on Prefrontal Cortex Interneurons and Pyramidal Neurons , 2007, The Journal of Neuroscience.
[49] P. Goldman-Rakic. Cellular basis of working memory , 1995, Neuron.
[50] M. Cairns,et al. Increased inflammatory markers identified in the dorsolateral prefrontal cortex of individuals with schizophrenia , 2013, Molecular Psychiatry.
[51] R. Kahn,et al. Schizophrenia is a cognitive illness: time for a change in focus. , 2013, JAMA psychiatry.
[52] David A. Lewis,et al. Cortical parvalbumin interneurons and cognitive dysfunction in schizophrenia , 2012, Trends in Neurosciences.
[53] Kazuya Iwamoto,et al. Altered expression of mitochondria-related genes in postmortem brains of patients with bipolar disorder or schizophrenia, as revealed by large-scale DNA microarray analysis. , 2005, Human molecular genetics.
[54] Qian Cai,et al. Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration , 2012, Nature Reviews Neuroscience.
[55] P. Penzes,et al. Long‐term perturbation of spine plasticity results in distinct impairments of cognitive function , 2012, Journal of neurochemistry.
[56] M. Uittenbogaard,et al. The neurogenic basic helix-loop-helix transcription factor NeuroD6 enhances mitochondrial biogenesis and bioenergetics to confer tolerance of neuronal PC12-NeuroD6 cells to the mitochondrial stressor rotenone. , 2012, Experimental cell research.
[57] Danko D. Georgiev,et al. Deficits in transcriptional regulators of cortical parvalbumin neurons in schizophrenia. , 2012, The American journal of psychiatry.
[58] M C O'Donovan,et al. Copy number variation in schizophrenia in Sweden , 2014, Molecular Psychiatry.
[59] A. Sampson,et al. Decreased somal size of deep layer 3 pyramidal neurons in the prefrontal cortex of subjects with schizophrenia. , 2001, Archives of general psychiatry.
[60] Rafael A Irizarry,et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. , 2003, Biostatistics.