Structural modifications of N-arylamide oxadiazoles: Identification of N-arylpiperidine oxadiazoles as potent and selective agonists of CB2.
暂无分享,去创建一个
Xiao Mei Zheng | S. Hitchcock | A. Cheng | R. Fremeau | Liyue Huang | E. Dimauro | R. Emkey | Xingwen Li | V. Patel | J. L. Buchanan | Josie H. Lee | Matthew W. Martin | Susan A. Tomlinson | Ryan D. White | Mingyao Huang | Brett Janosky | Ming Y. Huang | J. Lee
[1] F. Ito,et al. The SAR studies of novel CB2 selective agonists, benzimidazolone derivatives. , 2008, Bioorganic & medicinal chemistry letters.
[2] Michael Koblish,et al. Sulfamoyl benzamides as novel CB2 cannabinoid receptor ligands. , 2008, Bioorganic & medicinal chemistry letters.
[3] Bie M. P. Verbist,et al. 5-Sulfonyl-benzimidazoles as selective CB2 agonists. , 2008, Bioorganic & medicinal chemistry letters.
[4] B. Dymock,et al. Arylsulfonamide CB2 receptor agonists: SAR and optimization of CB2 selectivity. , 2008, Bioorganic & medicinal chemistry letters.
[5] E. Högenauer,et al. Latest advances in the cannabinoids , 2007 .
[6] M. Cascio,et al. New 1,8-naphthyridine and quinoline derivatives as CB2 selective agonists. , 2007, Bioorganic & medicinal chemistry letters.
[7] Y. Toda,et al. N-Alkylidenearylcarboxamides as new potent and selective CB(2) cannabinoid receptor agonists with good oral bioavailability. , 2007, Bioorganic & medicinal chemistry letters.
[8] D. Pagé,et al. New 1,2,3,4-tetrahydropyrrolo[3,4-b]indole derivatives as selective CB2 receptor agonists. , 2007, Bioorganic & medicinal chemistry letters.
[9] G. Muccioli. Blocking the Cannabinoid Receptors: Drug Candidates and Therapeutic Promises , 2007, Chemistry & biodiversity.
[10] S. Hitchcock,et al. Targeting cannabinoid agonists for inflammatory and neuropathic pain , 2007, Expert opinion on investigational drugs.
[11] I. Chessell,et al. Discovery of 2-[(2,4-dichlorophenyl)amino]-N-[(tetrahydro- 2H-pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide, a selective CB2 receptor agonist for the treatment of inflammatory pain. , 2007, Journal of medicinal chemistry.
[12] K. Valenzano,et al. The role of the cannabinoid CB2 receptor in pain transmission and therapeutic potential of small molecule CB2 receptor agonists. , 2007, Current medicinal chemistry.
[13] P. Lazzari,et al. Tricyclic pyrazoles. 4. Synthesis and biological evaluation of analogues of the robust and selective CB2 cannabinoid ligand 1-(2',4'-dichlorophenyl)-6-methyl-N-piperidin-1-yl-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide. , 2006, Journal of medicinal chemistry.
[14] A. Vannacci,et al. Design, synthesis, and biological evaluation of new 1,8-naphthyridin-4(1H)-on-3-carboxamide and quinolin-4(1H)-on-3-carboxamide derivatives as CB2 selective agonists. , 2006, Journal of medicinal chemistry.
[15] A. Poso,et al. Synthesis and SAR studies of 2-oxoquinoline derivatives as CB2 receptor inverse agonists. , 2006, Journal of medicinal chemistry.
[16] Philippe Chavatte,et al. Novel 4-oxo-1,4-dihydroquinoline-3-carboxamide derivatives as new CB2 cannabinoid receptors agonists: synthesis, pharmacological properties and molecular modeling. , 2006, Journal of medicinal chemistry.
[17] Ken Mackie,et al. Cannabinoid receptors as therapeutic targets. , 2006, Annual review of pharmacology and toxicology.
[18] J. Cheetham,et al. An Automated Screening Assay for Determination of Aqueous Equilibrium Solubility Enabling SPR Study During Drug Lead Optimization , 2005 .
[19] C. Fowler,et al. The endocannabinoid system: drug targets, lead compounds, and potential therapeutic applications. , 2005, Journal of medicinal chemistry.
[20] T. Nevalainen,et al. Targeting the cannabinoid CB2 receptor: mutations, modeling and development of CB2 selective ligands. , 2005, Current medicinal chemistry.
[21] S. Narula,et al. Triaryl bis-sulfones as a new class of cannabinoid CB2 receptor inhibitors: identification of a lead and initial SAR studies. , 2005, Bioorganic & medicinal chemistry letters.
[22] Paul A Keller,et al. Control of hepatitis C: a medicinal chemistry perspective. , 2005, Journal of medicinal chemistry.
[23] R. Hampson,et al. Cannabinoid physiology and pharmacology: 30 years of progress , 2004, Neuropharmacology.
[24] T. Vanderah,et al. CB2 cannabinoid receptor-mediated peripheral antinociception , 2001, Pain.
[25] M. Tramèr,et al. Are cannabinoids an effective and safe treatment option in the management of pain? A qualitative systematic review , 2001, BMJ : British Medical Journal.
[26] N. Kaminski,et al. Inhibition of the cAMP signaling cascade via cannabinoid receptors: a putative mechanism of immune modulation by cannabinoid compounds. , 1998, Toxicology letters.
[27] N. Kaminski,et al. Inhibition of the cyclic AMP signaling cascade and nuclear factor binding to CRE and kappaB elements by cannabinol, a minimally CNS-active cannabinoid. , 1998, Biochemical pharmacology.
[28] M. Johnson,et al. Selective and Potent Analgetics Derived from Cannabinoids , 1981, Journal of clinical pharmacology.
[29] Stephen L. Buchwald,et al. New insights into Xantphos/Pd-Catalyzed C-N bond forming reactions : A structural and kinetic study , 2006 .
[30] A. Molleman,et al. Cannabinoid signalling (review) , 2006 .
[31] B. Martin,et al. Neurobiology of marijuana abuse. , 1992, Trends in pharmacological sciences.