An improved synthesis and biological evaluation of a new cage-like bifunctional chelator, 4-((8-amino-3,6,10,13,16,19-hexaazabicyclo[6.6.6]icosane-1-ylamino)methyl)benzoic acid, for 64Cu radiopharmaceuticals.

[1]  P. Conti,et al.  Synthesis of a novel bifunctional chelator AmBaSar based on sarcophagine for peptide conjugation and (64)Cu radiolabelling. , 2009, Dalton transactions.

[2]  T. Nayak,et al.  Radioimmunoimaging with longer-lived positron-emitting radionuclides: potentials and challenges. , 2009, Bioconjugate chemistry.

[3]  S. Achilefu,et al.  (64)Cu-labeled CB-TE2A and diamsar-conjugated RGD peptide analogs for targeting angiogenesis: comparison of their biological activity. , 2009, Nuclear medicine and biology.

[4]  Samantha V. Sublett,et al.  In vitro and in vivo analysis of [(64)Cu-NO2A-8-Aoc-BBN(7-14)NH(2)]: a site-directed radiopharmaceutical for positron-emission tomography imaging of T-47D human breast cancer tumors. , 2009, Nuclear medicine and biology.

[5]  J. Steinbach,et al.  Hexadentate bispidine derivatives as versatile bifunctional chelate agents for copper(II) radioisotopes. , 2009, Bioconjugate chemistry.

[6]  Anna M. Wu,et al.  Antibodies and Antimatter: The Resurgence of Immuno-PET , 2008, Journal of Nuclear Medicine.

[7]  M. Gleave,et al.  Evaluation of novel bifunctional chelates for the development of Cu-64-based radiopharmaceuticals. , 2008, Nuclear medicine and biology.

[8]  Shuang Liu.  Bifunctional coupling agents for radiolabeling of biomolecules and target-specific delivery of metallic radionuclides. , 2008, Advanced drug delivery reviews.

[9]  Katsunori Tanaka,et al.  PET (positron emission tomography) imaging of biomolecules using metal-DOTA complexes: a new collaborative challenge by chemists, biologists, and physicians for future diagnostics and exploration of in vivo dynamics. , 2008, Organic & biomolecular chemistry.

[10]  L. Spiccia,et al.  Synthesis, Copper(II) Complexation, (64)Cu-Labeling, and Bioconjugation of a New Bis(2-pyridylmethyl) Derivative of 1,4,7-Triazacyclononane. , 2008, Bioconjugate chemistry.

[11]  Smith Sv.  Sarar technology for the application of Copper-64 in biology and materials science. , 2008 .

[12]  S. Treves,et al.  Positron emission tomography (PET) imaging of neuroblastoma and melanoma with 64Cu-SarAr immunoconjugates , 2007, Proceedings of the National Academy of Sciences.

[13]  C. Anderson,et al.  Copper chelation chemistry and its role in copper radiopharmaceuticals. , 2007, Current pharmaceutical design.

[14]  N. Di Bartolo,et al.  New 64Cu PET imaging agents for personalised medicine and drug development using the hexa-aza cage, SarAr. , 2006, Organic & biomolecular chemistry.

[15]  Suzanne V. Smith.  Molecular imaging with copper-64. , 2004, Journal of inorganic biochemistry.

[16]  Peter S. Conti,et al.  Pegylated Arg-Gly-Asp Peptide: 64Cu Labeling and PET Imaging of Brain Tumor αvβ3-Integrin Expression , 2004 .

[17]  Ryan Park,et al.  MicroPET and autoradiographic imaging of breast cancer alpha v-integrin expression using 18F- and 64Cu-labeled RGD peptide. , 2004, Bioconjugate chemistry.

[18]  A. Sargeson,et al.  Synthesis of a new cage ligand, SarAr, and its complexation with selected transition metal ions for potential use in radioimaging , 2001 .

[19]  J. Lewis,et al.  Copper radionuclides and radiopharmaceuticals in nuclear medicine. , 1996, Nuclear medicine and biology.

[20]  A. Beatty,et al.  Synthesis and Characterization of Cobalt-Cage Complexes with Pendant Phenol Groups. , 1996, Inorganic chemistry.