Insight into Genotype-Phenotype Associations through eQTL Mapping in Multiple Cell Types in Health and Immune-Mediated Disease
暂无分享,去创建一个
Kenneth G. C. Smith | Mary D. Fortune | S. Richardson | James C. Lee | Arianne C. Richard | P. Lyons | J. Peters | P. Newcombe
[1] Roby Joehanes,et al. Identification of common genetic variants controlling transcript isoform variation in human whole blood , 2015, Nature Genetics.
[2] Y. Okada,et al. Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy , 2015, Nature Genetics.
[3] M. S. Ramakrishnan,et al. Efficacy and safety of itolizumab, a novel anti-CD6 monoclonal antibody, in patients with moderate to severe chronic plaque psoriasis: results of a double-blind, randomized, placebo-controlled, phase-III study. , 2014, Journal of the American Academy of Dermatology.
[4] Chun Jimmie Ye,et al. Intersection of population variation and autoimmunity genetics in human T cell activation , 2014, Science.
[5] S. Jameson,et al. The self-obsession of T cells: how TCR signaling thresholds affect fate 'decisions' and effector function , 2014, Nature Immunology.
[6] Daphne Koller,et al. Polarization of the Effects of Autoimmune and Neurodegenerative Risk Alleles in Leukocytes , 2014, Science.
[7] R. Andrews,et al. Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression , 2014, Science.
[8] Chun Jimmie Ye,et al. Common Genetic Variants Modulate Pathogen-Sensing Responses in Human Dendritic Cells , 2014, Science.
[9] Tariq Ahmad,et al. Human SNP Links Differential Outcomes in Inflammatory and Infectious Disease to a FOXO3-Regulated Pathway , 2013, Cell.
[10] Julien Gagneur,et al. Genotype-Environment Interactions Reveal Causal Pathways That Mediate Genetic Effects on Phenotype , 2013, PLoS genetics.
[11] L. Harrison,et al. T cell regulation mediated by interaction of soluble CD52 with the inhibitory receptor Siglec-10 , 2013, Nature Immunology.
[12] C. Wallace,et al. Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics , 2013, PLoS genetics.
[13] M. Stephens,et al. A Statistical Framework for Joint eQTL Analysis in Multiple Tissues , 2012, PLoS genetics.
[14] Q. Lu,et al. Heritability versus the role of the environment in autoimmunity. , 2012, Journal of autoimmunity.
[15] Shane J. Neph,et al. Systematic Localization of Common Disease-Associated Variation in Regulatory DNA , 2012, Science.
[16] Panos Deloukas,et al. Genetically distinct subsets within ANCA-associated vasculitis. , 2012, The New England journal of medicine.
[17] Joseph E. Powell,et al. The Brisbane Systems Genetics Study: Genetical Genomics Meets Complex Trait Genetics , 2012, PloS one.
[18] John A. Todd,et al. Statistical colocalization of monocyte gene expression and genetic risk variants for type 1 diabetes , 2012, Human molecular genetics.
[19] R. Durbin,et al. Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses , 2012, Nature Protocols.
[20] F. Vannberg,et al. GENETICS OF GENE EXPRESSION IN PRIMARY IMMUNE CELLS IDENTIFIES CELL-SPECIFIC MASTER REGULATORS AND ROLES OF HLA ALLELES , 2012, Nature Genetics.
[21] Miles Parkes,et al. Gene expression profiling of CD8+ T cells predicts prognosis in patients with Crohn disease and ulcerative colitis. , 2011, The Journal of clinical investigation.
[22] Simon C. Potter,et al. The Architecture of Gene Regulatory Variation across Multiple Human Tissues: The MuTHER Study , 2011, PLoS genetics.
[23] Tariq Ahmad,et al. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci , 2010, Nature Genetics.
[24] Rafael A. Irizarry,et al. A framework for oligonucleotide microarray preprocessing , 2010, Bioinform..
[25] R. Gentleman,et al. Independent filtering increases detection power for high-throughput experiments , 2010, Proceedings of the National Academy of Sciences.
[26] Jing Cui,et al. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci , 2010, Nature Genetics.
[27] Leopold Parts,et al. A Bayesian Framework to Account for Complex Non-Genetic Factors in Gene Expression Levels Greatly Increases Power in eQTL Studies , 2010, PLoS Comput. Biol..
[28] A. Brazma,et al. A CD8 T cell transcription signature predicts prognosis in autoimmune disease , 2010, Nature Medicine.
[29] David M. Tobin,et al. The lta4h Locus Modulates Susceptibility to Mycobacterial Infection in Zebrafish and Humans , 2010, Cell.
[30] Ying Wang,et al. Genomewide association study of leprosy. , 2009, The New England journal of medicine.
[31] Johan Van Limbergen,et al. Common variants at five new loci associated with early-onset inflammatory bowel disease , 2009, Nature Genetics.
[32] P. Deloukas,et al. Common Regulatory Variation Impacts Gene Expression in a Cell Type–Dependent Manner , 2009, Science.
[33] Manabu T. Nakamura,et al. Disruption of FADS2 gene in mice impairs male reproduction and causes dermal and intestinal ulceration , 2009, Journal of Lipid Research.
[34] F. Collins,et al. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits , 2009, Proceedings of the National Academy of Sciences.
[35] Robert Gentleman,et al. Data structures and algorithms for analysis of genetics of gene expression with Bioconductor: GGtools 3.x , 2009, Bioinform..
[36] A. Hess,et al. Filtering for increased power for microarray data analysis , 2009, BMC Bioinformatics.
[37] M. Stephens,et al. High-Resolution Mapping of Expression-QTLs Yields Insight into Human Gene Regulation , 2008, PLoS genetics.
[38] M. LeBlanc,et al. Increasing the power of identifying gene × gene interactions in genome‐wide association studies , 2008, Genetic epidemiology.
[39] L. Kruglyak,et al. Gene–Environment Interaction in Yeast Gene Expression , 2008, PLoS biology.
[40] D. Koller,et al. Population genomics of human gene expression , 2007, Nature Genetics.
[41] Anbupalam Thalamuthu,et al. TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study. , 2007, The New England journal of medicine.
[42] Manuel A. R. Ferreira,et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. , 2007, American journal of human genetics.
[43] Kenneth G. C. Smith,et al. Microarray analysis of human leucocyte subsets: the advantages of positive selection and rapid purification , 2007, BMC Genomics.
[44] Rafael A Irizarry,et al. Exploration, normalization, and genotype calls of high-density oligonucleotide SNP array data. , 2006, Biostatistics.
[45] Judy H. Cho,et al. Materials for : Host-microbe interactions shape genetic risk for inflammatory bowel disease , 2012 .
[46] Cheng Li,et al. Adjusting batch effects in microarray expression data using empirical Bayes methods. , 2007, Biostatistics.
[47] Trevor Hastie,et al. The Elements of Statistical Learning , 2001 .