Bisphenol A in the Aquatic Environment and Its Endocrine-Disruptive Effects on Aquatic Organisms

Bisphenol A [BPA; 2,2-bis(4-hydroxyphenyl)propane], which is mainly used in the production of epoxy resins and polycarbonate plastics, is a known endocrine disruptor and is acutely toxic to aquatic organisms. Due to intensified usage of these products, exposure of organisms to BPA via several routes, such as the environment and food, has increased. The aquatic environment is an important area for the study of BPA. This report reviews the literature concerning contamination routes and degradation of BPA in the aquatic environment and its endocrine-disruptive effects on aquatic organisms.

[1]  P. Ricci,et al.  Endocrine disruptors , 1996 .

[2]  Feng Wu,et al.  Photodegradation of bisphenol A in simulated lake water containing algae, humic acid and ferric ions. , 2006, Environmental pollution.

[3]  Mayuko F Kato,et al.  Effects of bisphenol A on thyroid hormone-dependent up-regulation of thyroid hormone receptor α and β and down-regulation of retinoid X receptor γ in Xenopus tail culture , 2006 .

[4]  F. Kondo,et al.  Distribution and Biodegradation of Bisphenol A in Water Hyacinth , 2006, Bulletin of environmental contamination and toxicology.

[5]  Yoshiki Katayama,et al.  Human exposure to bisphenol A. , 2006, Toxicology.

[6]  H. Köhler,et al.  An invertebrate embryo test with the apple snail Marisa cornuarietis to assess effects of potential developmental and endocrine disruptors. , 2006, Chemosphere.

[7]  G. Janer,et al.  Endocrine disruptors in marine organisms: approaches and perspectives. , 2006, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

[8]  R. Opitz,et al.  Effects of tetrabromobisphenol A on larval development and thyroid hormone-regulated biomarkers of the amphibian Xenopus laevis. , 2006, Environmental research.

[9]  J. Seo,et al.  Endocrine disrupting chemicals (bisphenol A, 4-nonylphenol, 4-tert-octylphenol) modulate expression of two distinct cytochrome P450 aromatase genes differently in gender types of the hermaphroditic fish Rivulus marmoratus. , 2006, Biochemical and biophysical research communications.

[10]  D. Barceló,et al.  Chemical monitoring and occurrence of alkylphenols, alkylphenol ethoxylates, alcohol ethoxylates, phthalates and benzothiazoles in sewage treatment plants and receiving waters along the Ter River basin (Catalonia, N. E. Spain) , 2006, Analytical and bioanalytical chemistry.

[11]  C. Bolognesi,et al.  Assessment of micronuclei induction in peripheral erythrocytes of fish exposed to xenobiotics under controlled conditions. , 2006, Aquatic toxicology.

[12]  A. Fogarty,et al.  Multi-generational effects of four selected environmental oestrogens on Daphnia magna. , 2006, Chemosphere.

[13]  B. Mai,et al.  Simultaneous determination of endocrine-disrupting phenols and steroid estrogens in sediment by gas chromatography-mass spectrometry. , 2006, Journal of chromatography. A.

[14]  A. Brenner,et al.  Biodegradability of tetrabromobisphenol A and tribromophenol by activated sludge , 2006, Ecotoxicology.

[15]  B. Mattiasson,et al.  Sequential removal of heavy metals ions and organic pollutants using an algal-bacterial consortium. , 2006, Chemosphere.

[16]  H. Kawasaki,et al.  Developmental and triiodothyronine-induced expression of genes encoding preprotemporins in the skin of Tago's brown frog Rana tagoi. , 2006, General and comparative endocrinology.

[17]  Xi Yang,et al.  Photosensitized degradation of bisphenol A involving reactive oxygen species in the presence of humic substances. , 2006, Chemosphere.

[18]  M. Ortiz-Zarragoitia,et al.  Biomarkers of Exposure and Reproduction-Related Effects in Mussels Exposed to Endocrine Disruptors , 2006, Archives of environmental contamination and toxicology.

[19]  Zijian Wang,et al.  Acute and early life stage toxicity of industrial effluent on Japanese medaka (Oryzias latipes). , 2006, Science of the Total Environment.

[20]  H. Budzinski,et al.  Alteration of Steroid Hormone Balance in Juvenile Turbot (Psetta maxima) Exposed to Nonylphenol, Bisphenol A, Tetrabromodiphenyl Ether 47, Diallylphthalate, Oil, and Oil Spiked with Alkylphenols , 2006, Archives of environmental contamination and toxicology.

[21]  Y. Katayama,et al.  Biodegradation or metabolism of bisphenol A: from microorganisms to mammals. , 2006, Toxicology.

[22]  Julie E Goodman,et al.  An Updated Weight of the Evidence Evaluation of Reproductive and Developmental Effects of Low Doses of Bisphenol A , 2006, Critical reviews in toxicology.

[23]  Anders Goksøyr.  Endocrine Disruptors in the Marine Environment: Mechanisms of Toxicity and their Influence on Reproductive Processes in Fish , 2006, Journal of toxicology and environmental health. Part A.

[24]  Y. Xu,et al.  Endocrine-Disrupting Effects of Nonylphenol, Bisphenol A, and p,p′-DDE on Rana nigromaculata Tadpoles , 2005, Bulletin of environmental contamination and toxicology.

[25]  F. Lahnsteiner,et al.  Effect of bisphenol A on maturation and quality of semen and eggs in the brown trout, Salmo trutta f. fario. , 2005, Aquatic toxicology.

[26]  T. Ternes,et al.  Bisphenol A Induces Superfeminization in the Ramshorn Snail (Gastropoda: Prosobranchia) at Environmentally Relevant Concentrations , 2005, Environmental health perspectives.

[27]  A. Olmstead,et al.  The screening of chemicals for juvenoid-related endocrine activity using the water flea Daphnia magna. , 2005, Aquatic toxicology.

[28]  Jeong-Hun Kang,et al.  Bisphenol A degradation in seawater is different from that in river water. , 2005, Chemosphere.

[29]  K. Miyamoto,et al.  Biodegradation of bisphenol a and disappearance of its estrogenic activity by the green alga Chlorella fusca var. vacuolata , 2005, Environmental toxicology and chemistry.

[30]  M. Gye,et al.  Bisphenol A Induces Hepatic Vitellogenin mRNA in Male Bombina orientalis , 2005, Bulletin of environmental contamination and toxicology.

[31]  D. Pampanin,et al.  Stress biomarkers and alkali-labile phosphate level in mussels (Mytilus galloprovincialis) collected in the urban area of Venice (Venice Lagoon, Italy). , 2005, Environmental pollution.

[32]  M. Canonaco,et al.  Effects of the xenoestrogen bisphenol A in diencephalic regions of the teleost fish Coris julis occur preferentially via distinct somatostatin receptor subtypes , 2005, Brain Research Bulletin.

[33]  A. D. Vethaak,et al.  An integrated assessment of estrogenic contamination and biological effects in the aquatic environment of The Netherlands. , 2005, Chemosphere.

[34]  H. Kimura,et al.  Toxic Effects of Bisphenol A on Sexual and Asexual Reproduction in Hydra oligactis , 2005, Archives of environmental contamination and toxicology.

[35]  C. A. Harris,et al.  Accurate Prediction of the Response of Freshwater Fish to a Mixture of Estrogenic Chemicals , 2005, Environmental health perspectives.

[36]  M. Iida,et al.  Anti-thyroid hormonal activity of tetrabromobisphenol A, a flame retardant, and related compounds: Affinity to the mammalian thyroid hormone receptor, and effect on tadpole metamorphosis. , 2005, Life sciences.

[37]  B. Zhu,et al.  In vitro and in vivo estrogenic activity of chlorinated derivatives of bisphenol A. , 2005, Toxicology.

[38]  Steffen Uhlig,et al.  The Elbe Flood in August 2002—Organic Contaminants in Sediment Samples Taken After the Flood Event , 2005, Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering.

[39]  M. van den Berg,et al.  Effects of environmental and natural estrogens on vitellogenin production in hepatocytes of the brown frog (Rana temporaria). , 2005, Aquatic toxicology.

[40]  J. Giesy,et al.  Horizontal and Vertical Distribution of Estrogenic Activities in Sediments and Waters from Tokyo Bay, Japan , 2005, Archives of environmental contamination and toxicology.

[41]  Danna Zhou,et al.  Photooxidation of bisphenol A (BPA) in water in the presence of ferric and carboxylate salts. , 2004, Water research.

[42]  Linda K. Weavers,et al.  Photosensitized degradation of bisphenol A by dissolved organic matter. , 2004, Environmental science & technology.

[43]  N. Ueno,et al.  Effects of 17β-estradiol, nonylphenol, and bisphenol-A on developing Xenopus laevis embryos , 2004 .

[44]  M. van den Berg,et al.  Effects of natural and synthetic estrogens and various environmental contaminants on vitellogenesis in fish primary hepatocytes: comparison of bream (Abramis brama) and carp (Cyprinus carpio). , 2004, Toxicological sciences : an official journal of the Society of Toxicology.

[45]  Y. Magara,et al.  The effect of bisphenol A and chlorinated derivatives of bisphenol A on the level of serum vitellogenin in Japanese medaka (Oryzias latipes). , 2004, Water science and technology : a journal of the International Association on Water Pollution Research.

[46]  F. Kondo,et al.  Streptomyces sp. strain isolated from river water has high bisphenol A degradability , 2004, Letters in applied microbiology.

[47]  J. Croué,et al.  Chlorination of bisphenol A: kinetics and by-products formation. , 2004, Chemosphere.

[48]  C. Basheer,et al.  Endocrine disrupting alkylphenols and bisphenol-A in coastal waters and supermarket seafood from Singapore. , 2004, Marine pollution bulletin.

[49]  Atsushi Suzuki,et al.  Endocrine disrupter nonylphenol and bisphenol A contamination in Okinawa and Ishigaki Islands, Japan--within coral reefs and adjacent river mouths. , 2004, Chemosphere.

[50]  M. Storelli,et al.  Interspecific variation in total arsenic body concentrations in elasmobranch fish from the Mediterranean Sea. , 2004, Marine pollution bulletin.

[51]  M. Marin,et al.  Vitellogenin induction as a biomarker of exposure to estrogenic compounds in aquatic environments. , 2004, Marine pollution bulletin.

[52]  I. Holopainen,et al.  Bisphenol A induces yolk-sac oedema and other adverse effects in landlocked salmon (Salmo salar m. sebago) yolk-sac fry. , 2004, Chemosphere.

[53]  H. Shiraishi,et al.  Numerical simulation of organic chemicals in a marine environment using a coupled 3D hydrodynamic and ecotoxicological model. , 2004, Marine pollution bulletin.

[54]  T. Nishimura,et al.  Bisphenol A induces apoptosis in central neural cells during early development of Xenopus laevis. , 2003, Biochemical and biophysical research communications.

[55]  Z. Ronen,et al.  Enrichment of a Microbial Culture Capable of Reductive Debromination of the Flame Retardant Tetrabromobisphenol-A, and Identification of the Intermediate Metabolites Produced in the Process , 2003, Biodegradation.

[56]  C. Tyler,et al.  Comparative responses of molluscs and fish to environmental estrogens and an estrogenic effluent. , 2003, Aquatic toxicology.

[57]  R. Verheyen,et al.  Comparison of vitellogenin responses in zebrafish and rainbow trout following exposure to environmental estrogens. , 2003, Ecotoxicology and environmental safety.

[58]  E. H. Luque,et al.  Sex reversal effects on Caiman latirostris exposed to environmentally relevant doses of the xenoestrogen bisphenol A. , 2003, General and comparative endocrinology.

[59]  D. Pickford,et al.  Assessing chronic toxicity of bisphenol A to larvae of the African clawed frog (Xenopus laevis) in a flow-through exposure system. , 2003, Chemosphere.

[60]  A. Hattori,et al.  Bisphenol A suppresses osteoclastic and osteoblastic activities in the cultured scales of goldfish. , 2003, Life sciences.

[61]  J. Oehlmann,et al.  Stimulated embryo production as a parameter of estrogenic exposure via sediments in the freshwater mudsnail Potamopyrgus antipodarum. , 2003, Aquatic toxicology.

[62]  Mayuko F Kato,et al.  Teratogenic and anti-metamorphic effects of bisphenol A on embryonic and larval Xenopus laevis. , 2003, General and comparative endocrinology.

[63]  R. Letcher,et al.  Metabolism in the toxicokinetics and fate of brominated flame retardants--a review. , 2003, Environment international.

[64]  K. Ishihara,et al.  Improvement of marine environmental pollution using eco-system: decomposition and recovery of endocrine disrupting chemicals by marine phyto- and zooplanktons , 2003 .

[65]  P. Darnerud.  Toxic effects of brominated flame retardants in man and in wildlife. , 2003, Environment international.

[66]  Y. Kamata,et al.  Effects of 17beta-estradiol, bisphenol A and tributyltin chloride on germ cells of Caenorhabditis elegans. , 2003, The Journal of veterinary medical science.

[67]  H. Reincke,et al.  Xenoestrogens in the River Elbe and its tributaries. , 2003, Environmental pollution.

[68]  A. Hattori,et al.  Bisphenol A Influences the Plasma Calcium Level and Inhibits Calcitonin Secretion in Goldfish , 2003, Zoological science.

[69]  P. Bjerregaard,et al.  Metabolism of bisphenol A in zebrafish (Danio rerio) and rainbow trout (Oncorhynchus mykiss) in relation to estrogenic response. , 2003, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

[70]  H. Tanaka,et al.  Evaluating bioaccumulation of suspected endocrine disruptors into periphytons and benthos in the Tama River. , 2003, Water science and technology : a journal of the International Association on Water Pollution Research.

[71]  M Fuerhacker,et al.  Bisphenol A emission factors from industrial sources and elimination rates in a sewage treatment plant. , 2003, Water science and technology : a journal of the International Association on Water Pollution Research.

[72]  Miquel Riera-Codina,et al.  Analysis of highly phosphorylated inositols in avian and crocodilian erythrocytes. , 2003, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

[73]  T. Urase,et al.  Factors affecting the concentration of bisphenol A in leachates from solid waste disposal sites and its fate in treatment processes , 2003 .

[74]  J. Yonekubo,et al.  Leaching of bisphenol A (BPA) to seawater from polycarbonate plastic and its degradation by reactive oxygen species. , 2003, Chemosphere.

[75]  K. Yamauchi,et al.  Competitive interactions of chlorinated phenol compounds with 3,3',5-triiodothyronine binding to transthyretin: detection of possible thyroid-disrupting chemicals in environmental waste water. , 2003, Toxicology and applied pharmacology.

[76]  Rai S. Kookana,et al.  Degradation of Five Selected Endocrine-Disrupting Chemicals in Seawater and Marine Sediment , 2003 .

[77]  E. Caramão,et al.  Identification of some plasticizers compounds in landfill leachate. , 2003, Chemosphere.

[78]  K. Carroll,et al.  Exposure to 17 alpha-ethinylestradiol and bisphenol A--effects on larval moulting and mouthpart structure of Chironomus riparius. , 2003, Ecotoxicology and environmental safety.

[79]  S. Holm,et al.  Selected resin acids in effluent and receiving waters derived from a bleached and unbleached kraft pulp and paper mill , 2003, Environmental toxicology and chemistry.

[80]  Chulwoo Lee,et al.  Choriogenin mRNA induction in male medaka, Oryzias latipes as a biomarker of endocrine disruption. , 2002, Aquatic toxicology.

[81]  Jeong-Hun Kang,et al.  Effects of bacterial counts and temperature on the biodegradation of bisphenol A in river water. , 2002, Chemosphere.

[82]  K. Nakao,et al.  Thyroid hormone action is disrupted by bisphenol A as an antagonist. , 2002, The Journal of clinical endocrinology and metabolism.

[83]  I. Kang,et al.  Effects of bisphenol a on the reproduction of Japanese medaka (Oryzias latipes) , 2002, Environmental toxicology and chemistry.

[84]  D. Vethaak,et al.  Occurrence of bisphenol A in surface water and uptake in fish: evaluation of field measurements. , 2002, Chemosphere.

[85]  F. Kondo,et al.  Bisphenol A Degradation by Bacteria Isolated from River Water , 2002, Archives of environmental contamination and toxicology.

[86]  R. Nozawa,et al.  Identification of estrogenic activity of chlorinated bisphenol A using a GFP expression system. , 2002, Environmental toxicology and pharmacology.

[87]  D. Barceló,et al.  Determination of toxic compounds in paper-recycling process waters by gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry. , 2002, Journal of chromatography. A.

[88]  J. Kukkonen,et al.  EFFECTS OF BISPHENOL A AND ARTIFICIAL UVB RADIATION ON THE EARLY DEVELOPMENT OF Rana Temporaria , 2002, Journal of toxicology and environmental health. Part A.

[89]  H. Yokota,et al.  High glucuronidation activity of environmental estrogens in the carp (Cyprinus carpino) intestine. , 2002, Life sciences.

[90]  K. Carroll,et al.  Toxicity of 17α-Ethinylestradiol and Bisphenol A to the Freshwater Cnidarian Hydra vulgaris , 2002, Archives of environmental contamination and toxicology.

[91]  I. Holopainen,et al.  Bisphenol A Accumulation in the Freshwater Clam Pisidium amnicum at Low Temperatures , 2002, Archives of environmental contamination and toxicology.

[92]  H. Shiraishi,et al.  Formation of chlorinated derivatives of bisphenol A in waste paper recycling plants and their estrogenic activities , 2002 .

[93]  S. Kitamura,et al.  Thyroid hormonal activity of the flame retardants tetrabromobisphenol A and tetrachlorobisphenol A. , 2002, Biochemical and biophysical research communications.

[94]  Jianying Hu,et al.  Products of aqueous chlorination of bisphenol A and their estrogenic activity. , 2002, Environmental science & technology.

[95]  S. Kashiwada,et al.  Fish test for endocrine-disruption and estimation of water quality of Japanese rivers. , 2002, Water research.

[96]  April Hill,et al.  Toxic effects of endocrine disrupters on freshwater sponges: common developmental abnormalities. , 2002, Environmental pollution.

[97]  A. Yasuhara,et al.  Chlorination of bisphenol A in aqueous media: formation of chlorinated bisphenol A congeners and degradation to chlorinated phenolic compounds. , 2002, Chemosphere.

[98]  Thomas Otto,et al.  Occurrence of phthalates and bisphenol A and F in the environment. , 2002, Water research.

[99]  H. Yokota,et al.  Developmental increases in rat hepatic microsomal UDP-glucuronosyltransferase activities toward xenoestrogens and decreases during pregnancy. , 2002, Environmental health perspectives.

[100]  D. Fennell,et al.  Anaerobic biotransformation of tetrabromobisphenol A, tetrachlorobisphenol A, and bisphenol A in estuarine sediments. , 2002, Environmental science & technology.

[101]  G. Klečka,et al.  Biodegradation of bisphenol a in aquatic environments: River die‐away , 2001, Environmental toxicology and chemistry.

[102]  U. Bolz,et al.  Phenolic xenoestrogens in surface water, sediments, and sewage sludge from Baden-Württemberg, south-west Germany. , 2001, Environmental pollution.

[103]  P. Bjerregaard,et al.  Uptake, metabolism and excretion of bisphenol A in the rainbow trout (Oncorhynchus mykiss). , 2001, Aquatic toxicology.

[104]  J. Giesy,et al.  Morphological effects of Bisphenol-A on the early life stages of medaka (Oryzias latipes). , 2001, Chemosphere.

[105]  K. Carroll,et al.  Chronic exposure to 17α-ethinylestradiol and bisphenol A-effects on development and reproduction in the freshwater invertebrate Chironomus riparius (Diptera: Chironomidae) , 2001 .

[106]  H. Reincke,et al.  The occurrence of xenoestrogens in the Elbe river and the North Sea. , 2001, Chemosphere.

[107]  H. Matsushita,et al.  Identification and quantification of chlorinated bisphenol A in wastewater from wastepaper recycling plants. , 2001, Chemosphere.

[108]  R. J. West,et al.  Assessment of the Ready Biodegradability of Bisphenol A , 2001, Bulletin of environmental contamination and toxicology.

[109]  K. Ballschmiter,et al.  Determination of endocrine-disrupting phenolic compounds and estrogens in surface and drinking water by HRGC-(NCI)-MS in the picogram per liter range. , 2001, Environmental science & technology.

[110]  J. Sumpter,et al.  Reproductive effects of long-term exposure to Bisphenol A in the fathead minnow (Pimephales promelas). , 2001, Environmental science & technology.

[111]  G. Callard,et al.  Estrogen and xenoestrogens upregulate the brain aromatase isoform (P450aromB) and perturb markers of early development in zebrafish (Danio rerio). , 2001, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

[112]  S Sakai,et al.  Estrogenic and dioxin-like potency in each step of a controlled landfill leachate treatment plant in Japan. , 2001, Chemosphere.

[113]  I. Meerts,et al.  In vitro estrogenicity of polybrominated diphenyl ethers, hydroxylated PDBEs, and polybrominated bisphenol A compounds. , 2001, Environmental health perspectives.

[114]  K. Kang,et al.  Effects of nonylphenol, bisphenol a, and their mixture on the viviparous swordtail fish (Xiphophorus helleri) , 2001, Environmental toxicology and chemistry.

[115]  O Nakasugi,et al.  Bisphenol A in hazardous waste landfill leachates. , 2001, Chemosphere.

[116]  T. Croley,et al.  Estrogenic potency of chemicals detected in sewage treatment plant effluents as determined by in vivo assays with Japanese medaka (Oryzias latipes) , 2001, Environmental toxicology and chemistry.

[117]  R. Shingai,et al.  Effects of Bisphenol A and its Derivatives on the Response of GABAA Receptors Expressed in Xenopus Oocytes , 2001, Bioscience, biotechnology, and biochemistry.

[118]  Bernd Markert,et al.  Effects of Endocrine Disruptors on Prosobranch Snails (Mollusca: Gastropoda) in the Laboratory. Part I: Bisphenol A and Octylphenol as Xeno-Estrogens , 2000, Ecotoxicology.

[119]  M. Gage,et al.  Reduced sperm counts in guppies (Poecilia reticulata) following exposure to low levels of tributyltin and bisphenol A , 2000, Proceedings of the Royal Society of London. Series B: Biological Sciences.

[120]  H. Bolt,et al.  Toxicokinetics of bisphenol A in female DA/Han rats after a single i.v. and oral administration , 2000, Archives of Toxicology.

[121]  F. Gagné,et al.  Evaluation of environmental estrogens with a fish cell line , 2000, Bulletin of environmental contamination and toxicology.

[122]  M. Ike,et al.  Biodegradation of bisphenol A in the aquatic environment , 2000 .

[123]  S. Scharf,et al.  Bisphenol A: emissions from point sources. , 2000, Chemosphere.

[124]  Y. Oshima,et al.  Effect of bisphenol a on the early life stage in Japanese medaka (Oryzias latipes) , 2000 .

[125]  Aharon Abeliovich,et al.  Anaerobic-Aerobic Process for Microbial Degradation of Tetrabromobisphenol A , 2000, Applied and Environmental Microbiology.

[126]  Arukwe,et al.  Effects of xenoestrogen treatment on zona radiata protein and vitellogenin expression in Atlantic salmon (Salmo salar). , 2000, Aquatic toxicology.

[127]  Hing-Biu Lee,et al.  Bisphenol A Contamination in Canadian Municipal and Industrial Wastewater and Sludge Samples , 2000 .

[128]  Pedersen,et al.  Estrogenic response of bisphenol A in rainbow trout (Oncorhynchus mykiss). , 2000, Aquatic Toxicology.

[129]  L. R. Harris,et al.  Bisphenol A concentrations in receiving waters near US manufacturing and processing facilities. , 2000, Chemosphere.

[130]  H. B. Lee,et al.  Determination of bisphenol A in sewage effluent and sludge by solid-phase and supercritical fluid extraction and gas chromatography/mass spectrometry. , 2000, Journal of AOAC International.

[131]  T. Shioda,et al.  Effect of certain chemicals on the reproduction of medaka (Oryzias latipes). , 2000, Chemosphere.

[132]  H. Andersen,et al.  A parameter for detecting estrogenic exposure in the copepod Acartia tonsa. , 1999, Ecotoxicology and environmental safety.

[133]  M. van den Berg,et al.  Estrogenic potencies of several environmental pollutants, as determined by vitellogenin induction in a carp hepatocyte assay. , 1999, Toxicological sciences : an official journal of the Society of Toxicology.

[134]  S. Ikushiro,et al.  Glucuronidation of the environmental oestrogen bisphenol A by an isoform of UDP-glucuronosyltransferase, UGT2B1, in the rat liver. , 1999, The Biochemical journal.

[135]  F. Gagné,et al.  Estrogenic Effects of Organic Environmental Extracts with the Trout Hepatocyte Vitellogenin Assay , 1999, Bulletin of environmental contamination and toxicology.

[136]  A. Yasuhara,et al.  Quantities of bisphenol a leached from plastic waste samples. , 1999, Chemosphere.

[137]  M. Pettersson,et al.  ETHINYLOESTRADIOL - AN UNDESIRED FISH CONTRACEPTIVE , 1999 .

[138]  R. Einspanier,et al.  Amphibians as a model to study endocrine disruptors: II. Estrogenic activity of environmental chemicals in vitro and in vivo. , 1999, The Science of the total environment.

[139]  I. Lutz,et al.  Amphibians as a model to study endocrine disruptors: I. Environmental pollution and estrogen receptor binding. , 1999, The Science of the total environment.

[140]  W D Pennie,et al.  Differential activation by xenoestrogens of ER alpha and ER beta when linked to different response elements. , 1998, The Journal of endocrinology.

[141]  L. R. Harris,et al.  A review of the environmental fate, effects, and exposures of bisphenol A. , 1998, Chemosphere.

[142]  T. Visser,et al.  Interactions of Persistent Environmental Organohalogens With the Thyroid Hormone System: Mechanisms and Possible Consequences for Animal and Human Health , 1998, Toxicology and industrial health.

[143]  Edward A. Boyle,et al.  What controls dissolved iron concentrations in the world ocean? — a comment , 1997 .

[144]  A. Arukwe,et al.  Fish zona radiata (eggshell) protein: a sensitive biomarker for environmental estrogens. , 1997, Environmental health perspectives.

[145]  M. Green,et al.  Comparison of stably expressed rat UGT1.1 and UGT2B1 in the glucuronidation of opioid compounds. , 1997, Drug metabolism and disposition: the biological fate of chemicals.

[146]  J. Tata,et al.  Differential responses to ligands of overexpressed thyroid hormone and retinoid X receptors in a Xenopus cell line and in vivo , 1997, Molecular and Cellular Endocrinology.

[147]  道彦 池,et al.  河川水マイクロコズムによるビスフェノールA（BPA）の分解 , 1996 .

[148]  C. Davis,et al.  Ultrastructure of the gonad and gametogenesis in the eastern oyster,Crassostrea virginica. I. Ovary and oogenesis , 1996 .

[149]  J. Sumpter,et al.  Vitellogenesis as a biomarker for estrogenic contamination of the aquatic environment. , 1995, Environmental health perspectives.

[150]  C. Haux,et al.  Formation of the vitelline envelope precedes the active uptake of vitellogenin during oocyte development in the rainbow trout,Oncorhynchus mykiss , 1994, Molecular reproduction and development.

[151]  D. Feldman,et al.  Bisphenol-A: an estrogenic substance is released from polycarbonate flasks during autoclaving. , 1993, Endocrinology.

[152]  J. Tata,et al.  Developmental and regional expression of thyroid hormone receptor genes during Xenopus metamorphosis. , 1991, Development.

[153]  Y. Yaoita,et al.  A correlation of thyroid hormone receptor gene expression with amphibian metamorphosis. , 1990, Genes & development.

[154]  Y. Yaoita.  Xenopus laevis α and β thyroid hormone receptors , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[155]  A Wolfenden,et al.  Handbook of Environmental Fate and Exposure Data for Organic Chemicals , 1990 .

[156]  Y. Yaoita,et al.  Xenopus laevis alpha and beta thyroid hormone receptors. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[157]  B. Burchell,et al.  UDP-glucuronosyltransferases: a family of detoxifying enzymes. , 1990, Trends in pharmacological sciences.

[158]  R. Pipe.  Oogenesis in the marine mussel Mytilus edulis: an ultrastructural study , 1987 .

[159]  M. Imbriani,et al.  [Bisphenol A]. , 2008, Giornale italiano di medicina del lavoro ed ergonomia.

[160]  F. Kondo,et al.  Bisphenol A in the Surface Water and Freshwater Snail Collected from Rivers Around a Secure Landfill , 2006, Bulletin of environmental contamination and toxicology.

[161]  M. Kawano,et al.  Hydroxylated polychlorinated biphenyls (OH-PCBs): recent advances in wildlife contamination study. , 2005, Environmental sciences : an international journal of environmental physiology and toxicology.

[162]  I. Lutz,et al.  Bisphenol A induces feminization in Xenopus laevis tadpoles. , 2004, Environmental research.

[163]  Guo-lan Huang,et al.  Simultaneous determination of 4-tert-octylphenol, 4-nonylphenol and bisphenol A in Guanting Reservoir using gas chromatography-mass spectrometry with selected ion monitoring. , 2004, Journal of environmental sciences.

[164]  T. Matsuto,et al.  Behavior of endocrine-disrupting chemicals in leachate from MSW landfill sites in Japan. , 2004, Waste management.

[165]  Kazuhisa Miyamoto,et al.  Removal of hazardous phenols by microalgae under photoautotrophic conditions. , 2003, Journal of bioscience and bioengineering.

[166]  T. Kayano,et al.  Molecular Characterization of a cDNA Encoding Putative Vitellogenin from the Pacific Oyster Crassostrea gigas , 2003, Zoological science.

[167]  W. Kloas.  Amphibians as a model for the study of endocrine disruptors. , 2002, International review of cytology.

[168]  S. Kadota,et al.  Sulfation of environmental estrogens by cytosolic human sulfotransferases. , 2002, Drug metabolism and pharmacokinetics.

[169]  J. Yonekubo,et al.  Degradation of bisphenol-A (BPA) in the presence of reactive oxygen species and its acceleration by lipids and sodium chloride. , 2002, Chemosphere.

[170]  A. Yasuhara,et al.  Analytical Chemistry for Environmental and Human Health. Determination of bisphenol A migrated from polyvinyl chloride hoses by GC/MS. , 2000 .

[171]  T. Matsuo,et al.  Constituents of Organic Pollutants in Leachates from Different Types of Landfill Sites and Their Fate in the Treatment Processes. , 1999 .

[172]  A. Brooks,et al.  Differential activation by xenoestrogens of ERα and ERβ when linked to different response elements , 1998 .

[173]  K. Miyamoto,et al.  Selective cadmium removal from hard water using NaOH-treated cells of the cyanobacterium Tolypothrix tenuis , 1997 .

[174]  M. Ike,et al.  Biodegradation of bisphenol A (BPA) by river water microcosms , 1996 .

[175]  Ladd W. Smith,et al.  Bisphenol A: acute aquatic toxicity , 1988 .

[176]  P. Dorn,et al.  DEGRADATION OF BISPHENOL A IN NATURAL WATERS , 1987 .

[177]  G. Matsumoto.  Comparative study on organic constituents in polluted and unpolluted inland aquatic environments—III: Phenols and aromatic acids in polluted and unpolluted waters , 1982 .

[178]  R. Ishiwatari,et al.  Gas chromatographic-mass spectrometric identification of phenols and aromatic acids in river waters , 1977 .

[179]  M R Franklin,et al.  Toxic effects. , 1977, Science.

[180]  Endocrine disruptors in the marine environment , 2022 .

[181]  K. Grandien,et al.  Printed in U.S.A. Copyright © 1997 by The Endocrine Society Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors � and � , 2022 .