Reference pricing systems in Europe: characteristics and consequences

Submitted: 16 May 2012; Revised: 8 August 2012; Accepted: 15 August 2012; Published online first: 17 August 2012 Introduction A reference pricing system is a system that establishes a reimbursement level or reference price for a group of interchangeable medicines. If a medicine is priced above the reference price, the patient pays the difference between the price of the medicine and the reference price, in addition to any other co-payments, e.g. prescription fee, percentage co-payment [1].

[1]  S. Simoens,et al.  The impact of reference-pricing systems in Europe: a literature review and case studies , 2011, Expert review of pharmacoeconomics & outcomes research.

[2]  S. Vogler,et al.  Comparing pharmaceutical pricing and reimbursement policies in Croatia to the European Union Member States , 2011, Croatian medical journal.

[3]  R. Busse,et al.  [Pharmaceutical reference pricing in Germany: definition of therapeutic groups, price setting through regression procedure and effects]. , 2005, Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)).

[4]  F. Fernandez‐Llimos,et al.  Antidepressant utilization in primary care in a Spanish region , 2007, Social Psychiatry and Psychiatric Epidemiology.

[5]  L. Garattini,et al.  Off-patent drugs in Italy. A short-sighted view? , 2006, The European journal of health economics : HEPAC : health economics in prevention and care.

[6]  C. Portela Reference pricing system and competition: case study from Portugal. , 2009, Croatian medical journal.

[7]  Marten Postma,et al.  Switch patterns before and after patent expiry of omeprazole: a case study in The Netherlands , 2006, Alimentary pharmacology & therapeutics.

[8]  Nina Pavcnik Do pharmaceutical prices respond to potential patient out-of-pocket expenses? , 2002 .

[9]  J. Puig-Junoy Impact of European Pharmaceutical Price Regulation on Generic Price Competition , 2012, PharmacoEconomics.

[10]  R. Busse,et al.  Arzneimittelfestbeträge: Gruppenbildung, Preisberechnung mittels Regressionsverfahren und Wirkungen , 2005 .

[11]  M. Petzold,et al.  Do policy changes in the pharmaceutical reimbursement schedule affect drug expenditures? Interrupted time series analysis of cost, volume and cost per volume trends in Sweden 1986-2002. , 2006, Health policy.

[12]  M. Miraldo,et al.  Effects of Reference Pricing in Pharmaceutical Markets , 2012, PharmacoEconomics.

[13]  S. Simoens,et al.  Pharmaceutical policy regarding generic drugs in Belgium , 2012, PharmacoEconomics.

[14]  P. Danzon,et al.  Reference Pricing of Pharmaceuticals for Medicare: Evidence from Germany, the Netherlands, and New Zealand , 2003, Frontiers in health policy research.

[15]  T. Stargardt The impact of reference pricing on switching behaviour and healthcare utilisation: the case of statins in Germany , 2010, The European Journal of Health Economics.

[16]  J. Puig-Junoy The impact of generic reference pricing interventions in the statin market. , 2007, Health policy.

[17]  Helle Håkonsen,et al.  Price control as a strategy for pharmaceutical cost containment - what has been achieved in Norway in the period 1994-2004? , 2009, Health policy.

[18]  Joan Costa-Font,et al.  Competition in Off-Patent Drug Markets: Issues, Regulation and Evidence , 2008 .

[19]  J. Puig-Junoy Do Higher-Priced Generic Medicines Enjoy a Competitive Advantage Under Reference Pricing? , 2012, Applied Health Economics and Health Policy.

[20]  L. Garattini,et al.  Off-patent drugs in Italy , 2006, The European Journal of Health Economics.

[21]  N. Muszbek,et al.  Does therapeutic reference pricing always result in cost-containment? The Hungarian evidence. , 2007, Health policy.

[22]  S. Simoens,et al.  Sustaining Generic Medicines Markets in Europe , 2006 .

[23]  Kurt R. Brekke,et al.  Regulation and Pricing of Pharmaceuticals: Reference Pricing or Price Cap Regulation? , 2007, SSRN Electronic Journal.

[24]  S. Vogler The impact of pharmaceutical pricing and reimbursement policies on generics uptake: implementation of policy options on generics in 29 European countries-an overview , 2012 .

[25]  A. Haycox,et al.  European countries with small populations can obtain low prices for drugs: Lithuania as a case history , 2011, Expert review of pharmacoeconomics & outcomes research.