Pre-pulseless Takayasu's arteritis evaluated with 18F-FDG positron emission tomography and gadolinium-enhanced magnetic resonance angiography.

Takayasu's arteritis is a primary vasculitis that affects large vessels and is characterized by chronic granulomatous inflammation. Diagnosis has been primarily clinical, with verification by angiography as the gold standard. More recently, however, it has become apparent that positron emission tomography enables better evaluation of vascular inflammation. This study presents 2 cases of Takayasu's arteritis. Magnetic resonance angiography was used to evaluate aortic anatomy by analyzing vascular wall thickness and also to quantify disease activity by measuring gadolinium enhancement. Positron emission tomography was used to evaluate active vascular inflammation by quantifying fluorodeoxyglucose F18 uptake. We conclude that both techniques support clinical diagnosis and aid in the evaluation of disease activity during and after treatment.

[1]  G. Hunder,et al.  The American College of Rheumatology 1990 criteria for the classification of Takayasu arteritis. , 2010, Arthritis and rheumatism.

[2]  K. Ishii,et al.  Aortic wall inflammation due to Takayasu arteritis imaged with 18F-FDG PET coregistered with enhanced CT. , 2005, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[3]  A. Al-nahhas,et al.  The role of 18F-FDG PET in characterising disease activity in Takayasu arteritis , 2004, European Journal of Nuclear Medicine and Molecular Imaging.

[4]  P. Merkel,et al.  Diagnostic imaging in Takayasu arteritis , 2004, Current opinion in rheumatology.

[5]  F. Strutz,et al.  Early diagnosis and follow-up of aortitis with [18F]FDG PET and MRI , 2003, European Journal of Nuclear Medicine and Molecular Imaging.

[6]  A. Al-nahhas,et al.  Takayasu’s arteritis: management of left main stem stenosis , 2003, Heart.

[7]  E. Grabbe,et al.  Value of F-18 FDG hybrid camera PET and MRI in early takayasu aortitis , 2003, European Radiology.

[8]  M. Gompels,et al.  Takayasu arteritis: a review. , 2002, Journal of clinical pathology.

[9]  J. Pickard,et al.  Imaging Atherosclerotic Plaque Inflammation With [18F]-Fluorodeoxyglucose Positron Emission Tomography , 2002, Circulation.

[10]  U. Müller-Ladner,et al.  Clinical image: occult large vessel vasculitis diagnosed by PET imaging , 2001, Rheumatology International.

[11]  M. Béhé,et al.  Fever of unknown origin: prospective comparison of [18F]FDG imaging with a double-head coincidence camera and gallium-67 citrate SPET , 2000, European Journal of Nuclear Medicine.

[12]  J. Bogaert,et al.  Positron emission tomography scan in the diagnosis and follow-up of aortitis of the thoracic aorta. , 2000, Acta cardiologica.

[13]  A. Maes,et al.  Positron emission tomography in giant cell arteritis and polymyalgia rheumatica: evidence for inflammation of the aortic arch. , 2000, The American journal of medicine.

[14]  F. Numano,et al.  Angiographic findings of Takayasu arteritis: new classification. , 1996, International journal of cardiology.

[15]  P. Reyes,et al.  Takayasu arteritis in Mexico: a 38-year clinical perspective through literature review. , 1996, International journal of cardiology.

[16]  R. Wahl,et al.  Intratumoral distribution of tritiated fluorodeoxyglucose in breast carcinoma: I. Are inflammatory cells important? , 1995, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[17]  P. Reyes,et al.  Takayasu's arteritis in Mexico: a clinical review of 44 consecutive cases. , 1994, Clinical and experimental rheumatology.

[18]  Sidor Misović,et al.  [Takayasu arteritis]. , 2005, Medicinski pregled.

[19]  W. Oyen,et al.  Fluorine 18 fluorodeoxyglucose positron emission tomography in the diagnosis and follow-up of three patients with vasculitis. , 2004, The American journal of medicine.

[20]  P. Goodman,et al.  FDG-PET finding in early-phase Takayasu arteritis. , 1999, Journal of computer assisted tomography.

[21]  E. Lupi-Herrera,et al.  Takayasu's arteritis. Clinical study of 107 cases. , 1977, American heart journal.