Vertebral Deformities and Functional Impairment in Men and Women

The objective of this study was to assess the prevalence and health effects of vertebral deformities in men and women. The study was carried out as part of the cross‐sectional baseline phase of The Rotterdam Study, a prospective population‐based cohort study of residents aged 55 years or over of a district of Rotterdam, The Netherlands. The prevalence of vertebral deformities according to a modification of the Eastell method and concomitant functional impairment were assessed in a random sample of 750 men and 750 women. The prevalence of moderate (grade I) vertebral deformities was 8 and 7% in men and women, respectively. For severe deformities (grade II), these percentages were 4 and 8%. In men, the prevalence of both moderate and severe deformities increased with age. In women, however, the prevalence of moderate vertebral deformities remained constant, opposite to a marked increase in severe deformities. Moderate vertebral deformity was significantly associated with impaired rising in men only. Severe vertebral deformity was associated with a significantly increased risk of general disability and the use of a walking aid in both men and women, impaired bending in men, and impaired rising in women. It is concluded that (1) vertebral deformities are only slightly less common in men than in women from the general population and (2) severe progression with age occurs in women only and (3) severe vertebral deformity is, particularly in men, related to functional impairment.

[1]  E. Orwoll,et al.  Vertebral deformity in men , 1992, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[2]  R. Eastell,et al.  Classification of vertebral fractures , 1991, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[3]  S. Soraci,et al.  Assessment of patient satisfaction in activities of daily living using a modified Stanford Health Assessment Questionnaire. , 1983, Arthritis and rheumatism.

[4]  D. Gold,et al.  Association of osteoporotic vertebral compression fractures with impaired functional status. , 1993, The American journal of medicine.

[5]  P. Geusens,et al.  Aging of the thoracic spine: distinction between wedging in osteoarthritis and fracture in osteoporosis--a cross-sectional and longitudinal study. , 1994, Bone.

[6]  D. Symmons,et al.  A longitudinal study of back pain and radiological changes in the lumbar spines of middle aged women. II. Radiographic findings. , 1991, Annals of the rheumatic diseases.

[7]  H K Genant,et al.  Contribution of vertebral deformities to chronic back pain and disability , 1992, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[8]  T. Spector,et al.  Prevalence of vertebral fracture in women and the relationship with bone density and symptoms: The chingford study , 1993, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[9]  J. R. Landis,et al.  The measurement of observer agreement for categorical data. , 1977, Biometrics.

[10]  D. Symmons Continuing medical education for the rheumatologist. , 1991, Annals of the rheumatic diseases.

[11]  J. Eisman,et al.  Lifestyle factors and bone density in the elderly: Implications for osteoporosis prevention , 1994, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[12]  A. Hofman,et al.  Age‐associated changes in ultrasound measurements of the calcaneus in men and women: The rotterdam study , 1994, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[13]  D. Symmons,et al.  A longitudinal study of back pain and radiological changes in the lumbar spines of middle aged women. I. Clinical findings. , 1991, Annals of the rheumatic diseases.

[14]  A. Hofman,et al.  The association between age and bone mineral density in men and women aged 55 years and over: the Rotterdam Study. , 1994, Bone and mineral.

[15]  E. Seeman Osteoporosis in men: epidemiology, pathophysiology, and treatment possibilities. , 1993, The American journal of medicine.

[16]  Robert Epstein,et al.  Comparison of methods for defining prevalent vertebral deformities: The study of osteoporotic fractures , 1995, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[17]  A. Silman,et al.  The prevalence of vertebral deformity in European men and women: The european vertebral osteoporosis study , 1996, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.