Responses of ventral cochlear nucleus units in the chinchilla to amplitude modulation by low-frequency, two-tone complexes.

For a tone that is amplitude modulated by two tones (fmod1 and fmod2), neither the stimulus waveform nor the half-wave rectified waveform has spectral energy at the envelope beat frequency (fmod2-fmod1). The response of ventral cochlear nucleus units in the chinchilla were recorded for best frequency tones that were amplitude modulated by low-frequency, two-tone complexes. Fourier analysis of poststimulus time histograms shows spectral peaks at fmod2-fmod1 in addition to the peaks at fmod1 and fmod2. The peaks in the neural spectra arise from compressive nonlinearities in the auditory system. The magnitudes of these spectral peaks are measures of synchrony at each frequency component. For all units, synchrony at fmod1 and fmod2 is greater than the synchrony at fmod2-fmod1. For a given unit, synchrony at fmod1 and fmod2 remains relatively constant as a function of overall level, whereas synchrony at fmod2-fmod1 decreases as the level increases. Synchrony was quantified in terms of the Rayleigh statistic (z), which is a measure of the statistical significance of the phase locking. In terms of z, phase locking at fmod1 and fmod2 is largest in chopper units, whereas onset-chopper units and primarylike units having sloping saturation in their rate-level functions show the smallest amount of phase locking. Phase locking at fmod2-fmod1 is also largest in chopper units, and smallest in onset-chopper units and primarylike units with sloping saturation.

[1]  R. C. Mathes,et al.  Phase Effects in Monaural Perception , 1947 .

[2]  J. E. Rose,et al.  A metal-filled microelectrode. , 1953, Science.

[3]  R. R. Pfeiffer Anteroventral Cochlear Nucleus:Wave Forms of Extracellularly Recorded Spike Potentials , 1966, Science.

[4]  I. A. Vartanian,et al.  TIME DEPENDENT FEATURES OF ADEQUATE SOUND STIMULI AND THE FUNCTIONAL ORGANIZATION OF CENTRAL AUDITORY NEURONS , 1973 .

[5]  D. K. Morest,et al.  Relations between auditory nerve endings and cell types in the cat's anteroventral cochlear nucleus seen with the Golgi method and nomarski optics , 1975, The Journal of comparative neurology.

[6]  Terrance Raymond Bourk,et al.  Electrical responses of neural units in the anteroventral cochlear nucleus of the cat , 1976 .

[7]  W. S. Rhode,et al.  Responses of fibers in the cat's auditory nerve to the cubic difference tone. , 1978, The Journal of the Acoustical Society of America.

[8]  Nell B. Cant,et al.  The bushy cells in the anteroventral cochlear nucleus of the cat. A study with the electron microscope , 1979, Neuroscience.

[9]  N. Viemeister Temporal modulation transfer functions based upon modulation thresholds. , 1979, The Journal of the Acoustical Society of America.

[10]  E. Batschelet Circular statistics in biology , 1981 .

[11]  N. Cant,et al.  The fine structure of two types of stellate cells in the anterior division of the anteroventral cochlear nucleus of the cat , 1981, Neuroscience.

[12]  R. Frisina,et al.  Anatomy and physiology of the gerbil cochlear nucleus: An improved surgical approach for microelectrode studies , 1982, Hearing Research.

[13]  D. Ryugo,et al.  Morphology of primary axosomatic endings in the anteroventral cochlear nucleus of the cat: A study of the endbulbs of Held , 1982, The Journal of comparative neurology.

[14]  D Henderson,et al.  Detection of sinusoidally amplitude modulated noise by the chinchilla. , 1979, The Journal of the Acoustical Society of America.

[15]  M. Ruggero,et al.  Chinchilla auditory-nerve responses to low-frequency tones. , 1983, The Journal of the Acoustical Society of America.

[16]  W. S. Rhode,et al.  Physiological response properties of cells labeled intracellularly with horseradish peroxidase in cat ventral cochlear nucleus , 1983, The Journal of comparative neurology.

[17]  W. S. Rhode,et al.  Physiological response properties of cells labeled intracellularly with horseradish peroxidase in cat dorsal cochlear nucleus , 1983, The Journal of comparative neurology.

[18]  R. Plomp The Role of Modulation in Hearing , 1983 .

[19]  E. Rouiller,et al.  Intracellular marking of physiologically characterized cells in the ventral cochlear nucleus of the cat , 1984, The Journal of comparative neurology.

[20]  Joseph W. Hall,et al.  Detection in noise by spectro-temporal pattern analysis. , 1984, The Journal of the Acoustical Society of America.

[21]  W. S. Rhode,et al.  Characterization of HRP‐labeled globular bushy cells in the cat anteroventral cochlear nucleus , 1987, The Journal of comparative neurology.

[22]  W. Shofner,et al.  Regularity and latency of units in ventral cochlear nucleus: implications for unit classification and generation of response properties. , 1988, Journal of neurophysiology.

[23]  C. Schreiner,et al.  Representation of amplitude modulation in the auditory cortex of the cat. II. Comparison between cortical fields , 1988, Hearing Research.

[24]  W. S. Rhode,et al.  Structural and functional properties distinguish two types of multipolar cells in the ventral cochlear nucleus , 1989, The Journal of comparative neurology.

[25]  S. Khanna,et al.  Spectral characteristics of the responses of primary auditory-nerve fibers to frequency-modulated signals , 1989, Hearing Research.

[26]  W A Yost,et al.  Modulation interference in detection and discrimination of amplitude modulation. , 1989, The Journal of the Acoustical Society of America.

[27]  S. Khanna,et al.  Spectral characteristics of the responses of primary auditory-nerve fibers to amplitude-modulated signals , 1989, Hearing Research.

[28]  A. Rees,et al.  Neuronal responses to amplitude-modulated and pure-tone stimuli in the guinea pig inferior colliculus, and their modification by broadband noise. , 1989, The Journal of the Acoustical Society of America.

[29]  I. Winter,et al.  Responses of single units in the anteroventral cochlear nucleus of the guinea pig , 1990, Hearing Research.

[30]  D. O. Kim,et al.  Responses of DCN-PVCN neurons and auditory nerve fibers in unanesthetized decerebrate cats to AM and pure tones: Analysis with autocorrelation/power-spectrum , 1990, Hearing Research.

[31]  A R Palmer,et al.  Temporal responses of primarylike anteroventral cochlear nucleus units to the steady-state vowel /i/. , 1990, The Journal of the Acoustical Society of America.

[32]  Robert D Frisina,et al.  Encoding of amplitude modulation in the gerbil cochlear nucleus: I. A hierarchy of enhancement , 1990, Hearing Research.

[33]  M. Sachs,et al.  The representations of the steady-state vowel sound /e/ in the discharge patterns of cat anteroventral cochlear nucleus neurons. , 1990, Journal of neurophysiology.

[34]  Ian M. Winter,et al.  Diversity of characteristic frequency rate-intensity functions in guinea pig auditory nerve fibres , 1990, Hearing Research.

[35]  W. Shofner,et al.  Temporal representation of rippled noise in the anteroventral cochlear nucleus of the chinchilla. , 1991, The Journal of the Acoustical Society of America.

[36]  Steven Greenberg,et al.  Physiology of the Cochlear Nuclei , 1992 .

[37]  T. Yin,et al.  Responses to amplitude-modulated tones in the auditory nerve of the cat. , 1992, The Journal of the Acoustical Society of America.

[38]  N. Cant,et al.  The Cochlear Nucleus: Neuronal Types and Their Synaptic Organization , 1992 .

[39]  M B Sachs,et al.  Neural encoding of single-formant stimuli in the cat. I. Responses of auditory nerve fibers. , 1993, Journal of neurophysiology.

[40]  J. Rothman,et al.  Convergence of auditory nerve fibers onto bushy cells in the ventral cochlear nucleus: implications of a computational model. , 1993, Journal of neurophysiology.

[41]  Malvin C. Teich,et al.  Spectral characteristics and synchrony in primary auditory-nerve fibers in response to pure-tone acoustic stimuli , 1993 .

[42]  E. Ostapoff,et al.  A physiological and structural study of neuron types in the cochlear nucleus. II. Neuron types and their structural correlation with response properties , 1994, The Journal of comparative neurology.

[43]  M. Sachs,et al.  Neural encoding of single-formant stimuli in the cat. II. Responses of anteroventral cochlear nucleus units. , 1994, Journal of neurophysiology.

[44]  W. S. Rhode,et al.  Encoding of amplitude modulation in the cochlear nucleus of the cat. , 1994, Journal of neurophysiology.

[45]  E. Young,et al.  The electrotonic structure of regular-spiking neurons in the ventral cochlear nucleus may determine their response properties. , 1994, Journal of neurophysiology.

[46]  L H Carney,et al.  Enhancement of neural synchronization in the anteroventral cochlear nucleus. I. Responses to tones at the characteristic frequency. , 1994, Journal of neurophysiology.

[47]  Hong-Bo Zhao,et al.  Processing of modulation frequency in the dorsal cochlear nucleus of the guinea pig: Amplitude modulated tones , 1995, Hearing Research.

[48]  A R Palmer,et al.  Level dependence of cochlear nucleus onset unit responses and facilitation by second tones or broadband noise. , 1995, Journal of neurophysiology.