TLR4 enhances TGF-β signaling and hepatic fibrosis
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Yosuke Osawa | R. Schwabe | D. Brenner | Y. Osawa | E. Seki | Robert F Schwabe | David A Brenner | Ekihiro Seki | Samuele De Minicis | Christoph H Österreicher | Johannes Kluwe | J. Kluwe | S. Minicis | C. Österreicher
[1] N. Van Rooijen,et al. Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications. , 1994, Journal of immunological methods.
[2] Ryan M. O’Connell,et al. Cutting Edge: TLR4 Activation Mediates Liver Ischemia/Reperfusion Inflammatory Response via IFN Regulatory Factor 3-Dependent MyD88-Independent Pathway1 , 2004, The Journal of Immunology.
[3] Jean S. Campbell,et al. Proinflammatory Cytokine Production in Liver Regeneration Is Myd88-Dependent, but Independent of Cd14, Tlr2, and Tlr41 , 2006, The Journal of Immunology.
[4] D. Brenner,et al. NFkappaB prevents apoptosis and liver dysfunction during liver regeneration. , 1998, The Journal of clinical investigation.
[5] K. Moore,et al. Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways , 2004, Nature Medicine.
[6] R. Schwabe,et al. IKKbeta phosphorylates p65 at S468 in transactivaton domain 2. , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[7] T. Akiyama,et al. Transcriptional regulation of the TGF-β pseudoreceptor BAMBI by TGF-β signaling , 2004 .
[8] S. Dooley,et al. Smad7 prevents activation of hepatic stellate cells and liver fibrosis in rats. , 2003, Gastroenterology.
[9] S. Akira,et al. Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. , 1998, Immunity.
[10] S. Akira,et al. Contribution of Toll‐like receptor/myeloid differentiation factor 88 signaling to murine liver regeneration , 2005, Hepatology.
[11] Jiahuai Han,et al. Identification of Lps2 as a key transducer of MyD88-independent TIR signalling , 2003, Nature.
[12] K. Tracey,et al. The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion , 2005, The Journal of experimental medicine.
[13] D. Brenner,et al. Erratum: Liver fibrosis (Journal of Clinical Investigation (2005) 115 (209-218) DOI:10.1172/JCI200524282) , 2005 .
[14] Olivia T. Abar,et al. A 7 gene signature identifies the risk of developing cirrhosis in patients with chronic hepatitis C , 2007, Hepatology.
[15] Kevin J. Tracey,et al. High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal , 2005, Nature Reviews Immunology.
[16] E. Burchardt,et al. Attenuation of CCl(4)-induced hepatic fibrosis by GdCl(3) treatment or dietary glycine. , 2001, American journal of physiology. Gastrointestinal and liver physiology.
[17] C. J. Marek,et al. Inhibition of inhibitor of kappaB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis. , 2005, Gastroenterology.
[18] Christian Jobin,et al. Toll‐Like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells , 2003, Hepatology.
[19] R. Bataller,et al. Amendment history : Corrigendum ( April 2005 ) Liver fibrosis Ramón Bataller , 2018 .
[20] R. Schwabe,et al. NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis. , 2003, The Journal of clinical investigation.
[21] S. Akira,et al. Lipopolysaccharide-Induced IL-18 Secretion from Murine Kupffer Cells Independently of Myeloid Differentiation Factor 88 That Is Critically Involved in Induction of Production of IL-12 and IL-1β1 , 2001, The Journal of Immunology.
[22] J. Abkowitz,et al. Kinetics of central nervous system microglial and macrophage engraftment: analysis using a transgenic bone marrow transplantation model. , 1997, Blood.
[23] T. Ahrens,et al. Oligosaccharides of Hyaluronan Activate Dendritic Cells via Toll-like Receptor 4 , 2002, The Journal of experimental medicine.
[24] C. Niehrs,et al. Silencing of TGF-β signalling by the pseudoreceptor BAMBI , 1999, Nature.
[25] M. Lotze,et al. Hepatic Ischemia/Reperfusion Injury Involves Functional TLR4 Signaling in Nonparenchymal Cells1 , 2005, The Journal of Immunology.
[26] A. Roberts,et al. Zebrafish nma is involved in TGFβ family signaling , 2000, Genesis.
[27] S. Forbes,et al. Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair. , 2005, The Journal of clinical investigation.
[28] Michael Karin,et al. IKKβ Couples Hepatocyte Death to Cytokine-Driven Compensatory Proliferation that Promotes Chemical Hepatocarcinogenesis , 2005, Cell.
[29] S. Kuhara,et al. Identification of BMP and Activin Membrane-bound Inhibitor (BAMBI), an Inhibitor of Transforming Growth Factor-β Signaling, as a Target of the β-Catenin Pathway in Colorectal Tumor Cells* , 2004, Journal of Biological Chemistry.
[30] K. Tracey,et al. Cutting Edge: High-Mobility Group Box 1 Preconditioning Protects against Liver Ischemia-Reperfusion Injury1 , 2006, The Journal of Immunology.
[31] Shizuo Akira,et al. Toll-like receptor signalling , 2004, Nature Reviews Immunology.
[32] S. Friedman,et al. Activation of cultured rat hepatic lipocytes by Kupffer cell conditioned medium. Direct enhancement of matrix synthesis and stimulation of cell proliferation via induction of platelet-derived growth factor receptors. , 1989, The Journal of clinical investigation.
[33] Y. Ben-Neriah,et al. NF-κB functions as a tumour promoter in inflammation-associated cancer , 2004, Nature.
[34] C. Hellerbrand,et al. LPS-mediated NFκB activation varies between activated human hepatic stellate cells from different donors , 2004 .
[35] Ruslan Medzhitov,et al. Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis , 2004, Cell.
[36] J. Rothstein,et al. Spontaneous production of tumor necrosis factor alpha by Kupffer cells of MRL/lpr mice , 1988, The Journal of experimental medicine.
[37] F. Chisari,et al. Toll-Like Receptor Signaling Inhibits Hepatitis B Virus Replication In Vivo , 2005, Journal of Virology.
[38] D. Brenner,et al. The role of gut‐derived bacterial toxins and free radicals in alcohol‐induced liver injury , 1998, Journal of gastroenterology and hepatology.
[39] G. Arteel,et al. Toll‐like receptor 4 is involved in the mechanism of early alcohol‐induced liver injury in mice , 2001, Hepatology.
[40] R. Schwabe,et al. Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis. , 2006, Journal of hepatology.
[41] R. Schwabe,et al. Toll-like receptor signaling in the liver. , 2006, Gastroenterology.
[42] R. Schwabe,et al. Gene expression profiles during hepatic stellate cell activation in culture and in vivo. , 2007, Gastroenterology.
[43] A. Diehl,et al. Cytokines and the pathogenesis of non-alcoholic steatohepatitis , 2005, Gut.
[44] S. Friedman. Molecular Regulation of Hepatic Fibrosis, an Integrated Cellular Response to Tissue Injury* , 2000, The Journal of Biological Chemistry.
[45] R. Schwabe,et al. Anandamide induces necrosis in primary hepatic stellate cells , 2005, Hepatology.
[46] T. Sasahira,et al. Effect of Nma on growth inhibition by TGF-betaa in human gastric carcinoma cell lines. , 2004, Oncology reports.
[47] G. Prestwich,et al. Regulation of lung injury and repair by Toll-like receptors and hyaluronan , 2005, Nature Medicine.
[48] Christopher J. Parsons,et al. LPS signaling enhances hepatic fibrogenesis caused by experimental cholestasis in mice. , 2006, American journal of physiology. Gastrointestinal and liver physiology.
[49] P. Brun,et al. Exposure to bacterial cell wall products triggers an inflammatory phenotype in hepatic stellate cells. , 2005, American journal of physiology. Gastrointestinal and liver physiology.
[50] D. Brenner,et al. DNase I–hypersensitive sites enhance α1(I) collagen gene expression in hepatic stellate cells , 2003 .