Kidney paired donation and its potential impact on transplantation.

This article updates the unique opportunities available to kidney transplant candidates through kidney paired donation (KPD). KPD enables kidney transplant candidates with willing but incompatible living donors to enroll in a registry of other incompatible pairs to find a compatible transplant. Because of the ongoing shortage of deceased donor organs, KPD represents the most promising opportunity to increase the number of kidneys available for transplantation.

[1]  G. Hil,et al.  National Kidney Registry: 213 transplants in three years. , 2010, Clinical transplants.

[2]  M. Utku Ünver,et al.  A nonsimultaneous, extended, altruistic-donor chain. , 2009, The New England journal of medicine.

[3]  A J Matas,et al.  Nondirected donation of kidneys from living donors. , 2000, The New England journal of medicine.

[4]  Jonathan Himmelfarb,et al.  Donor Kidney Exchanges , 2004, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[5]  A. Israni,et al.  Transporting Live Donor Kidneys for Kidney Paired Donation: Initial National Results , 2011, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[6]  J. Petrozzino,et al.  Efficacy, Outcomes, and Cost-Effectiveness of Desensitization Using IVIG and Rituximab , 2013, Transplantation.

[7]  M. Schnitzler,et al.  Call to Develop a Standard Acquisition Charge Model for Kidney Paired Donation , 2012, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[8]  J. Cecka,et al.  Calculated PRA: Initial Results Show Benefits for Sensitized Patients and a Reduction in Positive Crossmatches , 2011, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[9]  D. J. Kim,et al.  Clinical Outcomes of Multicenter Domino Kidney Paired Donation , 2009, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[10]  Darshana Dadhania,et al.  Living donor kidney paired donation transplantation: experience as a founding member center of the National Kidney Registry , 2012, Clinical transplantation.

[11]  A. Roth,et al.  Nonsimultaneous Chains and Dominos in Kidney‐ Paired Donation—Revisited , 2011, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[12]  M. Melcher,et al.  Chain Transplantation: Initial Experience of a Large Multicenter Program , 2012, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[13]  Frans H J Claas,et al.  Hurdles, Barriers, and Successes of a National Living Donor Kidney Exchange Program , 2008, Transplantation.

[14]  A. Bingaman,et al.  Single‐Center Kidney Paired Donation: The Methodist San Antonio Experience , 2012, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[15]  R. Montgomery,et al.  Using donor exchange paradigms with desensitization to enhance transplant rates among highly sensitized patients , 2011, Current opinion in organ transplantation.

[16]  P. Nickerson,et al.  Dynamic Challenges Inhibiting Optimal Adoption of Kidney Paired Donation: Findings of a Consensus Conference , 2013, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[17]  L. Kavoussi,et al.  Clinical results from transplanting incompatible live kidney donor/recipient pairs using kidney paired donation. , 2005, JAMA.

[18]  Robert A Montgomery,et al.  Utilization and Outcomes of Kidney Paired Donation in the United States , 2008, Transplantation.

[19]  S. Kim,et al.  Exchange-donor program in kidney transplantation. , 1999, Transplantation proceedings.

[20]  S. Crawford,et al.  Kidney Paired Donation: A Payer Perspective , 2012, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[21]  D. Segev,et al.  The Roles of Dominos and Nonsimultaneous Chains in Kidney Paired Donation , 2009, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[22]  P. Archdeacon,et al.  Summary of FDA Antibody‐Mediated Rejection Workshop , 2011, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[23]  D. Segev,et al.  Domino paired kidney donation: a strategy to make best use of live non-directed donation , 2006, The Lancet.

[24]  P. Chadha,et al.  Expanding the live kidney donor pool: ethical considerations regarding altruistic donors, paired and pooled programs. , 2011, Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation.

[25]  Yan Zhou,et al.  Graph-Based Optimization Algorithm and Software on Kidney Exchanges , 2012, IEEE Transactions on Biomedical Engineering.

[26]  Greg Bennett,et al.  High Transplant Rates of Highly Sensitized Recipients With Virtual Crossmatching in Kidney Paired Donation , 2012, Transplantation.

[27]  M. Fortin Is it ethical to invite compatible pairs to participate in exchange programmes? , 2013, Journal of Medical Ethics.

[28]  M. Utku Ünver,et al.  Utilizing List Exchange and Nondirected Donation through ‘Chain’ Paired Kidney Donations , 2006, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[29]  L. Ross,et al.  Ethics of a paired-kidney-exchange program. , 1997, The New England journal of medicine.

[30]  Lloyd E Ratner,et al.  The Altruistic Unbalanced Paired Kidney Exchange: Proof of Concept and Survey of Potential Donor and Recipient Attitudes , 2010, Transplantation.

[31]  Michael A Rees,et al.  Altruistic donation through the Alliance for Paired Donation. , 2009, Clinical transplants.

[32]  Rapaport Ft,et al.  The case for a living emotionally related international kidney donor exchange registry. , 1986 .

[33]  Lainie Friedman Ross,et al.  The Ethical Limits in Expanding Living Donor Transplantation , 2006, Kennedy Institute of Ethics journal.

[34]  M. Melcher,et al.  Kidney transplant chains amplify benefit of nondirected donors. , 2013, JAMA surgery.

[35]  Nathan T. James,et al.  Outcomes of ABO-Incompatible Kidney Transplantation in the United States , 2012, Transplantation.

[36]  E. Elster,et al.  Transplantation of A2 Kidneys into B and O Recipients Leads to Reduction in Waiting Time: USRDS Experience , 2010, Transplantation.

[37]  A. Kirk,et al.  Antibody‐Mediated Rejection—An Ounce of Prevention Is Worth a Pound of Cure , 2011, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.