Peroxiredoxins: guardians against oxidative stress and modulators of peroxide signaling.
暂无分享,去创建一个
P. Karplus | A. Perkins | L. Poole | K. Nelson | D. Parsonage | Kimberly J. Nelson | Leslie B. Poole | P. Andrew Karplus | Arden Perkins | Derek Parsonage
[1] C. Winterbourn,et al. The High Reactivity of Peroxiredoxin 2 with H2O2 Is Not Reflected in Its Reaction with Other Oxidants and Thiol Reagents* , 2007, Journal of Biological Chemistry.
[2] L. Poole,et al. Overview of peroxiredoxins in oxidant defense and redox regulation. , 2011, Current protocols in toxicology.
[3] P. Karplus,et al. Peroxiredoxin Evolution and the Regulation of Hydrogen Peroxide Signaling , 2003, Science.
[4] Patrick Griffin,et al. Peroxynitrite reductase activity of bacterial peroxiredoxins , 2000, Nature.
[5] Amir Karton,et al. Model for the Exceptional Reactivity of Peroxiredoxins 2 and 3 with Hydrogen Peroxide , 2011, The Journal of Biological Chemistry.
[6] Jacquelyn S Fetrow,et al. Structure-based active site profiles for genome analysis and functional family subclassification. , 2003, Journal of molecular biology.
[7] L. Netto,et al. Reactions of yeast thioredoxin peroxidases I and II with hydrogen peroxide and peroxynitrite: rate constants by competitive kinetics. , 2007, Free radical biology & medicine.
[8] M. Ushio-Fukai. Compartmentalization of redox signaling through NADPH oxidase-derived ROS. , 2009, Antioxidants & redox signaling.
[9] P Andrew Karplus,et al. Mapping the active site helix-to-strand conversion of CxxxxC peroxiredoxin Q enzymes. , 2012, Biochemistry.
[10] In Sup Kil,et al. Peroxiredoxin Functions as a Peroxidase and a Regulator and Sensor of Local Peroxides* , 2011, The Journal of Biological Chemistry.
[11] L. Netto,et al. Disulfide biochemistry in 2-cys peroxiredoxin: requirement of Glu50 and Arg146 for the reduction of yeast Tsa1 by thioredoxin. , 2012, Journal of molecular biology.
[12] P. Karplus,et al. The sensitive balance between the fully folded and locally unfolded conformations of a model peroxiredoxin. , 2013, Biochemistry.
[13] L. Flohé. Changing paradigms in thiology from antioxidant defense toward redox regulation. , 2010, Methods in enzymology.
[14] J. Winther,et al. Quantification of thiols and disulfides. , 2014, Biochimica et biophysica acta.
[15] V. Gladyshev,et al. Hydrogen Peroxide Probes Directed to Different Cellular Compartments , 2011, PloS one.
[16] S. Orkin,et al. Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression , 2003, Nature.
[17] P. Karplus,et al. Analysis of the link between enzymatic activity and oligomeric state in AhpC, a bacterial peroxiredoxin. , 2005, Biochemistry.
[18] Sue Goo Rhee,et al. Inactivation of Human Peroxiredoxin I during Catalysis as the Result of the Oxidation of the Catalytic Site Cysteine to Cysteine-sulfinic Acid* , 2002, The Journal of Biological Chemistry.
[19] M. Trujillo,et al. Kinetic studies of peroxiredoxin 6 from Arenicola marina: rapid oxidation by hydrogen peroxide and peroxynitrite but lack of reduction by hydrogen sulfide. , 2011, Archives of biochemistry and biophysics.
[20] P. Karplus,et al. Dimers to doughnuts: redox-sensitive oligomerization of 2-cysteine peroxiredoxins. , 2002, Biochemistry.
[21] A. Miele,et al. Moonlighting by different stressors: crystal structure of the chaperone species of a 2-Cys peroxiredoxin. , 2012, Structure.
[22] J. Kyte,et al. Structure in Protein Chemistry , 1995 .
[23] H. Forman,et al. Signaling functions of reactive oxygen species. , 2010, Biochemistry.
[24] G. Hou,et al. Peroxiredoxin 1 promotes tumorigenesis through regulating the activity of mTOR/p70S6K pathway in esophageal squamous cell carcinoma , 2015, Medical Oncology.
[25] T. Finkel,et al. Signal transduction by reactive oxygen species , 2011, The Journal of cell biology.
[26] M. Gil,et al. Nitration Transforms a Sensitive Peroxiredoxin 2 into a More Active and Robust Peroxidase* , 2014, The Journal of Biological Chemistry.
[27] M. Trujillo,et al. Oxidizing substrate specificity of Mycobacterium tuberculosis alkyl hydroperoxide reductase E: kinetics and mechanisms of oxidation and overoxidation. , 2011, Free radical biology & medicine.
[28] Laura Soito,et al. proteins STRUCTURE O FUNCTION O BIOINFORMATICS Analysis of the peroxiredoxin family: Using , 2022 .
[29] Sang Yeol Lee,et al. Two Enzymes in One Two Yeast Peroxiredoxins Display Oxidative Stress-Dependent Switching from a Peroxidase to a Molecular Chaperone Function , 2004, Cell.
[30] G. Whitesides,et al. RATES OF THIOL-DISULFIDE INTERCHANGE REACTIONS BETWEEN MONO- AND DITHIOLS AND ELLMAN′S REAGENT , 1977 .
[31] U. Jakob,et al. Mitochondrial peroxiredoxin functions as crucial chaperone reservoir in Leishmania infantum , 2015, Proceedings of the National Academy of Sciences.
[32] M. Toledano,et al. ATP-dependent reduction of cysteine–sulphinic acid by S. cerevisiae sulphiredoxin , 2003, Nature.
[33] W. Lowther,et al. Molecular Basis for the Resistance of Human Mitochondrial 2-Cys Peroxiredoxin 3 to Hyperoxidation* , 2013, The Journal of Biological Chemistry.
[34] P Andrew Karplus,et al. Evolutionary origin of a secondary structure: π-helices as cryptic but widespread insertional variations of α-helices that enhance protein functionality. , 2010, Journal of molecular biology.
[35] J. Engelhardt,et al. Signaling components of redox active endosomes: the redoxosomes. , 2009, Antioxidants & redox signaling.
[36] Cong-Zhao Zhou,et al. Structural Snapshots of Yeast Alkyl Hydroperoxide Reductase Ahp1 Peroxiredoxin Reveal a Novel Two-cysteine Mechanism of Electron Transfer to Eliminate Reactive Oxygen Species* , 2012, The Journal of Biological Chemistry.
[37] L. Netto,et al. Structural and biochemical characterization of peroxiredoxin Qbeta from Xylella fastidiosa: catalytic mechanism and high reactivity. , 2010, The Journal of biological chemistry.
[38] D. Barford,et al. Conformation-Sensing Antibodies Stabilize the Oxidized Form of PTP1B and Inhibit Its Phosphatase Activity , 2011, Cell.
[39] S. Rhee,et al. Multiple functions of peroxiredoxins: peroxidases, sensors and regulators of the intracellular messenger H₂O₂, and protein chaperones. , 2011, Antioxidants & redox signaling.
[40] J. Lambeth,et al. Nox4: A Hydrogen Peroxide-Generating Oxygen Sensor , 2014, Biochemistry.
[41] A B Reddy,et al. Molecular mechanisms of the circadian clockwork in mammals , 2014, FEBS letters.
[42] G. Church,et al. Cloning and sequencing of thiol-specific antioxidant from mammalian brain: alkyl hydroperoxide reductase and thiol-specific antioxidant define a large family of antioxidant enzymes. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[43] L. Poole. The basics of thiols and cysteines in redox biology and chemistry. , 2015, Free radical biology & medicine.
[44] Dae-Yeul Yu,et al. Inactivation of Peroxiredoxin I by Phosphorylation Allows Localized H2O2 Accumulation for Cell Signaling , 2010, Cell.
[45] L. Flohé,et al. Verification of the Interaction of a Tryparedoxin Peroxidase with Tryparedoxin by ESI-MS/MS , 2003, Biological chemistry.
[46] L. Poole,et al. Kinetic and thermodynamic features reveal that Escherichia coli BCP is an unusually versatile peroxiredoxin. , 2011, Biochemistry.
[47] N. Heintz,et al. Oxidation state governs structural transitions in peroxiredoxin II that correlate with cell cycle arrest and recovery , 2006, The Journal of cell biology.
[48] Jacquelyn S. Fetrow,et al. PREX: PeroxiRedoxin classification indEX, a database of subfamily assignments across the diverse peroxiredoxin family , 2010, Nucleic Acids Res..
[49] T. Nyström,et al. Peroxiredoxins, gerontogenes linking aging to genome instability and cancer. , 2012, Genes & development.
[50] P. Baiocco,et al. The Crystal Structures of the Tryparedoxin-Tryparedoxin Peroxidase Couple Unveil the Structural Determinants of Leishmania Detoxification Pathway , 2012, PLoS neglected tropical diseases.
[51] Kate S Carroll,et al. Peroxide-dependent sulfenylation of the EGFR catalytic site enhances kinase activity. , 2011, Nature chemical biology.
[52] Rafael Radi,et al. Factors affecting protein thiol reactivity and specificity in peroxide reduction. , 2011, Chemical research in toxicology.
[53] K. Ishikawa,et al. Crystal structure of peroxiredoxin from Aeropyrum pernix K1 complexed with its substrate, hydrogen peroxide. , 2010, Journal of biochemistry.
[54] Patricia C Babbitt,et al. Divergence of function in the thioredoxin fold suprafamily: evidence for evolution of peroxiredoxins from a thioredoxin-like ancestor. , 2004, Biochemistry.
[55] Yen-Ling Chen,et al. Reactive Oxygen Species Generation Is Involved in Epidermal Growth Factor Receptor Transactivation through the Transient Oxidization of Src Homology 2-Containing Tyrosine Phosphatase in Endothelin-1 Signaling Pathway in Rat Cardiac Fibroblasts , 2006, Molecular Pharmacology.
[56] P. Karplus,et al. Cysteine pK(a) values for the bacterial peroxiredoxin AhpC. , 2008, Biochemistry.
[57] L. Daniel,et al. Endosomal H2O2 production leads to localized cysteine sulfenic acid formation on proteins during lysophosphatidic acid-mediated cell signaling. , 2013, Free radical biology & medicine.
[58] F. Rodríguez-Pascual,et al. Hydrogen peroxide signaling in laminar shear stress , 2012 .
[59] H. Masutani,et al. Physiological Relevance of Antioxid/Redox Genes; Learning from Genetically Modified Animals , 2012 .
[60] P. Karplus,et al. Dissecting peroxiredoxin catalysis: separating binding, peroxidation, and resolution for a bacterial AhpC. , 2015, Biochemistry.
[61] P. Karplus,et al. Peroxiredoxins as molecular triage agents, sacrificing themselves to enhance cell survival during a peroxide attack. , 2012, Molecular cell.
[62] M. W. van der Kamp,et al. Combined quantum mechanics/molecular mechanics (QM/MM) methods in computational enzymology. , 2013, Biochemistry.
[63] P Andrew Karplus,et al. Structure-based Insights into the Catalytic Power and Conformational Dexterity of Peroxiredoxins , 2022 .
[64] S. Rhee. Intracellular Messenger Function of Hydrogen Peroxide and its Regulation by Peroxiredoxins , 2006 .
[65] M. Trujillo,et al. Thiol and sulfenic acid oxidation of AhpE, the one-cysteine peroxiredoxin from Mycobacterium tuberculosis: kinetics, acidity constants, and conformational dynamics. , 2009, Biochemistry.
[66] V. Gladyshev,et al. Thiol peroxidases mediate specific genome-wide regulation of gene expression in response to hydrogen peroxide , 2011, Proceedings of the National Academy of Sciences.
[67] Dean P. Jones,et al. A model of redox kinetics implicates the thiol proteome in cellular hydrogen peroxide responses. , 2010, Antioxidants & redox signaling.
[68] Z. A. Wood,et al. Structure, mechanism and regulation of peroxiredoxins. , 2003, Trends in biochemical sciences.
[69] D. Estrin,et al. The extraordinary catalytic ability of peroxiredoxins: a combined experimental and QM/MM study on the fast thiol oxidation step. , 2014, Chemical communications.
[70] P Andrew Karplus,et al. Structural evidence that peroxiredoxin catalytic power is based on transition-state stabilization. , 2010, Journal of molecular biology.
[71] J. Ayté,et al. Dissection of a redox relay: H2O2-dependent activation of the transcription factor Pap1 through the peroxidatic Tpx1-thioredoxin cycle. , 2013, Cell reports.
[72] V. Gladyshev,et al. Cysteine function governs its conservation and degeneration and restricts its utilization on protein surfaces. , 2010, Journal of molecular biology.
[73] R. Morita,et al. Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain , 2012, Nature Medicine.
[74] R. Cogdell,et al. Crystal Structure of Reduced and of Oxidized Peroxiredoxin IV Enzyme Reveals a Stable Oxidized Decamer and a Non-disulfide-bonded Intermediate in the Catalytic Cycle* , 2011, The Journal of Biological Chemistry.
[75] S. Choi,et al. Distinct Characteristics of Two 2-Cys Peroxiredoxins of Vibrio vulnificus Suggesting Differential Roles in Detoxifying Oxidative Stress* , 2012, The Journal of Biological Chemistry.
[76] C. Winterbourn,et al. Redox potential and peroxide reactivity of human peroxiredoxin 3. , 2009, Biochemistry.
[77] L. Flohé,et al. Kinetics of peroxiredoxins and their role in the decomposition of peroxynitrite. , 2007, Sub-cellular biochemistry.
[78] K. Feeney,et al. Circadian redox and metabolic oscillations in mammalian systems. , 2014, Antioxidants & redox signaling.
[79] P. Karplus,et al. Typical 2‐Cys peroxiredoxins – structures, mechanisms and functions , 2009, The FEBS journal.
[80] P. Karplus,et al. Peroxiredoxins in parasites. , 2012, Antioxidants & redox signaling.
[81] P. B. Chock,et al. Protein glutathionylation in the regulation of peroxiredoxins: a family of thiol-specific peroxidases that function as antioxidants, molecular chaperones, and signal modulators. , 2012, Antioxidants & redox signaling.
[82] M. Trujillo,et al. Pre-steady state kinetic characterization of human peroxiredoxin 5: taking advantage of Trp84 fluorescence increase upon oxidation. , 2007, Archives of biochemistry and biophysics.
[83] P. Karplus,et al. Evaluating peroxiredoxin sensitivity toward inactivation by peroxide substrates. , 2013, Methods in enzymology.
[84] P. Karplus,et al. A primer on peroxiredoxin biochemistry. , 2015, Free radical biology & medicine.
[85] L. Poole,et al. Cysteine reactivity and thiol-disulfide interchange pathways in AhpF and AhpC of the bacterial alkyl hydroperoxide reductase system. , 2007, Biochemistry.
[86] C. Winterbourn,et al. Hyperoxidation of Peroxiredoxins 2 and 3 , 2013, The Journal of Biological Chemistry.
[87] M. Trujillo,et al. The peroxidase and peroxynitrite reductase activity of human erythrocyte peroxiredoxin 2. , 2009, Archives of biochemistry and biophysics.
[88] S. Rhee,et al. Circadian rhythm of hyperoxidized peroxiredoxin II is determined by hemoglobin autoxidation and the 20S proteasome in red blood cells , 2014, Proceedings of the National Academy of Sciences.
[89] Carsten Schultz,et al. Does cellular hydrogen peroxide diffuse or act locally? , 2011, Antioxidants & redox signaling.
[90] B. Morgan,et al. Inactivation of a peroxiredoxin by hydrogen peroxide is critical for thioredoxin-mediated repair of oxidized proteins and cell survival. , 2012, Molecular cell.
[91] I. S. Kil,et al. Feedback control of adrenal steroidogenesis via H2O2-dependent, reversible inactivation of peroxiredoxin III in mitochondria. , 2012, Molecular cell.
[92] Alexander F. Christiansen,et al. Extraordinary μs-ms backbone dynamics in Arabidopsis thaliana peroxiredoxin Q. , 2011, Biochimica et biophysica acta.
[93] C. Winterbourn,et al. Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide. , 1999, Free radical biology & medicine.
[94] K. Dietz. Peroxiredoxins in plants and cyanobacteria. , 2011, Antioxidants & redox signaling.
[95] W. Markesbery,et al. Proteomic identification of nitrated brain proteins in early Alzheimer’s disease inferior parietal lobule , 2009, Journal of cellular and molecular medicine.
[96] B. Knoops,et al. Deconstructing the catalytic efficiency of peroxiredoxin-5 peroxidatic cysteine. , 2014, Biochemistry.
[97] C. Winterbourn,et al. Redox biology: signaling via a peroxiredoxin sensor. , 2015, Nature chemical biology.
[98] W. Lowther,et al. Reduction of cysteine sulfinic acid in eukaryotic, typical 2-Cys peroxiredoxins by sulfiredoxin. , 2011, Antioxidants & redox signaling.
[99] P. Karplus,et al. Tuning of Peroxiredoxin Catalysis for Various Physiological Roles , 2014, Biochemistry.
[100] G. Ferrer-Sueta,et al. Peroxiredoxins as preferential targets in H2O2-induced signaling. , 2013, Methods in enzymology.
[101] C. Winterbourn,et al. Reconciling the chemistry and biology of reactive oxygen species. , 2008, Nature chemical biology.
[102] L. Flohé,et al. A Unique Cascade of Oxidoreductases Catalyses Trypanothione-Mediated Peroxide Metabolism in Crithidia fasciculata , 1997, Biological chemistry.
[103] Kap-Seok Yang,et al. Reversing the Inactivation of Peroxiredoxins Caused by Cysteine Sulfinic Acid Formation , 2003, Science.
[104] V. Ferrans,et al. Requirement for Generation of H2O2 for Platelet-Derived Growth Factor Signal Transduction , 1995, Science.
[105] Michael J. Oehler,et al. Peroxiredoxin-2 and STAT3 form a redox relay for H2O2 signaling. , 2015, Nature chemical biology.