Cranial magnetic resonance imaging findings of leptomeningeal contrast enhancement after pediatric posterior fossa tumor resection and its significance.

In this report, the authors illustrate the potential shortfalls of early postoperative MR imaging following resection of a posterior fossa tumor. The authors present the cases of a 10-month-old boy and a 14-year-old boy with posterior fossa tumors that were surgically resected and monitored immediately postoperatively with MR imaging. The MR imaging study obtained immediately postresection while the children were still anesthetized revealed enhancing elements in both patients, which were suggestive of leptomeningeal metastases. When this signal was followed on subsequent MR images, it was no longer visible. The patients are both recurrence free at the time of this publication. These cases demonstrate that early postoperative MR imaging findings for leptomeningeal metastases may be unreliable after excision of posterior fossa tumors and may have potential implications for intraoperative MR imaging techniques currently under development.

[1]  D. Kurda,et al.  Ependymoma , 2010, Radiopaedia.org.

[2]  W. Banks,et al.  The blood–brain barrier and immune function and dysfunction , 2010, Neurobiology of Disease.

[3]  Nicolas Foroglou,et al.  Intra-operative MRI (iop-MR) for brain tumour surgery , 2009, British journal of neurosurgery.

[4]  J. Rutka,et al.  Initial Management of Childhood Brain Tumors: Neurosurgical Considerations , 2008, Journal of child neurology.

[5]  T. Witkamp,et al.  Postoperative hemicerebellar inflammation mimicking recurrent tumor after resection of a medulloblastoma. Case report. , 2008, Journal of neurosurgery. Pediatrics.

[6]  L. Solymosi,et al.  Subdural enhancement on postoperative spinal MRI after resection of posterior cranial fossa tumours , 2004, Neuroradiology.

[7]  P. Jabbour,et al.  Hemicerebellitis mimicking a tumour on MRI , 2003, Child's Nervous System.

[8]  R. Zimmerman,et al.  Postoperative evaluation for disseminated medulloblastoma involving the spine: contrast-enhanced MR findings, CSF cytologic analysis, timing of disease occurrence, and patient outcomes. , 2000, AJNR. American journal of neuroradiology.

[9]  M. Berger,et al.  Spinal subdural enhancement after suboccipital craniectomy. , 1996, AJNR. American journal of neuroradiology.

[10]  T. Park,et al.  Spinal magnetic resonance imaging immediately after craniotomy for detection of metastatic disease. , 1995, Pediatric Neurosurgery.

[11]  S. Meyers,et al.  Postoperative evaluation for intracranial recurrence of medulloblastoma: MR findings with gadopentetate dimeglumine. , 1994, AJNR. American journal of neuroradiology.

[12]  W. J. Oakes,et al.  False-positive MRI detection of recurrent or metastatic pediatric infratentorial tumors. , 1993, Medical and pediatric oncology.

[13]  W. J. Oakes,et al.  False-positive spinal MR findings for subarachnoid spread of primary CNS tumor in postoperative pediatric patients. , 1990, AJNR. American journal of neuroradiology.

[14]  D. Schellinger,et al.  Meningeal Gd‐DTPA Enhancement in Patients with Malignancies , 1990, Journal of computer assisted tomography.

[15]  A. Elster,et al.  Cranial postoperative site: assessment with contrast-enhanced MR imaging. , 1990, Radiology.