Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics
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[1] Madelaine Daianu,et al. Pericyte degeneration causes white matter dysfunction in the mouse central nervous system , 2018, Nature Medicine.
[2] S. Love,et al. Differing associations between Aβ accumulation, hypoperfusion, blood–brain barrier dysfunction and loss of PDGFRB pericyte marker in the precuneus and parietal white matter in Alzheimer's disease , 2017, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[3] P. McGuire,et al. The blood-brain barrier in psychosis. , 2018, The lancet. Psychiatry.
[4] K. Nave,et al. A bloody brake on myelin repair , 2017, Nature.
[5] Mark Ellisman,et al. Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage , 2017, Neuron.
[6] S. Strickland,et al. Fibrinogen in the Nervous System: Glia Beware , 2017, Neuron.
[7] B. Zlokovic,et al. Alzheimer’s disease: A matter of blood–brain barrier dysfunction? , 2017, The Journal of experimental medicine.
[8] C. Iadecola. The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease , 2017, Neuron.
[9] G. DeLuca,et al. Vascular pathology in multiple sclerosis: reframing pathogenesis around the blood-brain barrier , 2017, Journal of Neurology, Neurosurgery, and Psychiatry.
[10] R. Perera,et al. Fibrin(ogen) and neurodegeneration in the progressive multiple sclerosis cortex , 2017, Annals of neurology.
[11] M. Lynch,et al. FTY720 Attenuates Infection-Induced Enhancement of Aβ Accumulation in APP/PS1 Mice by Modulating Astrocytic Activation , 2017, Journal of Neuroimmune Pharmacology.
[12] D. Lodygin,et al. Laquinimod enhances central nervous system barrier functions , 2017, Neurobiology of Disease.
[13] K. Akassoglou,et al. Alzheimer disease makes new blood contacts. , 2017, Blood.
[14] S. Strickland,et al. Depletion of coagulation factor XII ameliorates brain pathology and cognitive impairment in Alzheimer disease mice. , 2017, Blood.
[15] M. Jorge Cardoso,et al. White matter hyperintensities are seen only in GRN mutation carriers in the GENFI cohort , 2017, NeuroImage: Clinical.
[16] B. Zlokovic,et al. Regional early and progressive loss of brain pericytes but not vascular smooth muscle cells in adult mice with disrupted platelet-derived growth factor receptor-β signaling , 2017, PloS one.
[17] H. Wiendl,et al. Prothrombin and factor X are elevated in multiple sclerosis patients , 2016, Annals of neurology.
[18] Dongmei Wang,et al. Elevated fibrinogen levels in neuromyelitis optica is associated with severity of disease , 2016, Neurological Sciences.
[19] S. Strickland,et al. The Alzheimer's disease peptide β‐amyloid promotes thrombin generation through activation of coagulation factor XII: reply , 2016, Journal of thrombosis and haemostasis : JTH.
[20] David A. Bennett,et al. Relation of Cerebral Vessel Disease to Alzheimer’s Disease Dementia and Cognitive Function in Older Persons: A Cross-sectional Study , 2016, The Lancet Neurology.
[21] C. Ruppert,et al. Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells , 2016, Nature Communications.
[22] S. Strickland,et al. A role for thrombin in the brain and circulation in Alzheimer's disease , 2016 .
[23] S. Strickland,et al. A possible new role for Aβ in vascular and inflammatory dysfunction in Alzheimer's disease. , 2016, Thrombosis research.
[24] Vicki Rosen,et al. BMP signalling in skeletal development, disease and repair , 2016, Nature Reviews Endocrinology.
[25] D. Lawrence,et al. A CCR2 macrophage endocytic pathway mediates extravascular fibrin clearance in vivo. , 2016, Blood.
[26] T. Renné,et al. The Alzheimer's disease peptide β‐amyloid promotes thrombin generation through activation of coagulation factor XII , 2016, Journal of thrombosis and haemostasis : JTH.
[27] Douglas H. Smith,et al. Blood-Brain Barrier Disruption Is an Early Event That May Persist for Many Years After Traumatic Brain Injury in Humans , 2015, Journal of Neuropathology and Experimental Neurology.
[28] Zhen Zhao,et al. Establishment and Dysfunction of the Blood-Brain Barrier , 2015, Cell.
[29] M. Brug,et al. Lack of Widespread BBB Disruption in Alzheimer’s Disease Models: Focus on Therapeutic Antibodies , 2015, Neuron.
[30] D. Izquierdo-Garcia,et al. Multisite Thrombus Imaging and Fibrin Content Estimation With a Single Whole-Body PET Scan in Rats , 2015, Arteriosclerosis, thrombosis, and vascular biology.
[31] W. Funkhouser,et al. APOE Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction , 2015, PLoS biology.
[32] Victoria A. Rafalski,et al. Breaking boundaries—coagulation and fibrinolysis at the neurovascular interface , 2015, Front. Cell. Neurosci..
[33] Sara G. Murray,et al. Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation , 2015, Nature Communications.
[34] Susan T Francis,et al. Cerebrovascular and blood–brain barrier impairments in Huntington's disease: Potential implications for its pathophysiology , 2015, Annals of neurology.
[35] Jiwon Kim,et al. Direct Imaging of Cerebral Thromboemboli Using Computed Tomography and Fibrin-targeted Gold Nanoparticles , 2015, Theranostics.
[36] M. Ota,et al. Increased cerebrospinal fluid fibrinogen in major depressive disorder , 2015, Scientific Reports.
[37] Britta Engelhardt,et al. Brain barriers: Crosstalk between complex tight junctions and adherens junctions , 2015, The Journal of cell biology.
[38] B. Frey,et al. Disruption in the Blood-Brain Barrier: The Missing Link between Brain and Body Inflammation in Bipolar Disorder? , 2015, Neural plasticity.
[39] T. Korff,et al. Dimethyl fumarate attenuates cerebral edema formation by protecting the blood–brain barrier integrity , 2015, Experimental Neurology.
[40] Jesse D. Sengillo,et al. GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration , 2015, Nature Neuroscience.
[41] T. Renné,et al. Activation of the factor XII-driven contact system in Alzheimer’s disease patient and mouse model plasma , 2015, Proceedings of the National Academy of Sciences.
[42] T. Kanda,et al. Fingolimod Prevents Blood-Brain Barrier Disruption Induced by the Sera from Patients with Multiple Sclerosis , 2015, PloS one.
[43] J. Woulfe,et al. Striatal Blood–Brain Barrier Permeability in Parkinson'S Disease , 2015, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[44] Lennart Thurfjell,et al. Blood protein predictors of brain amyloid for enrichment in clinical trials? , 2015, Alzheimer's & dementia.
[45] Sidney Strickland,et al. Fibrin deposited in the Alzheimer's disease brain promotes neuronal degeneration , 2015, Neurobiology of Aging.
[46] C. Jack,et al. Vascular and amyloid pathologies are independent predictors of cognitive decline in normal elderly , 2015, Brain : a journal of neurology.
[47] I. Ferrer,et al. Fibrinogen-Derived γ377-395 Peptide Improves Cognitive Performance and Reduces Amyloid-β Deposition, without Altering Inflammation, in AβPP/PS1 Mice. , 2015, Journal of Alzheimer's disease : JAD.
[48] Thomas Arzberger,et al. Frontotemporal lobar degeneration FTLD-tau: preclinical lesions, vascular, and Alzheimer-related co-pathologies , 2015, Journal of Neural Transmission.
[49] R. Aisina,et al. Structure and function of plasminogen/plasmin system , 2014, Russian Journal of Bioorganic Chemistry.
[50] D. Reich,et al. The formation of inflammatory demyelinated lesions in cerebral white matter , 2014, Annals of neurology.
[51] V. Gallo,et al. Glial Development: The Crossroads of Regeneration and Repair in the CNS , 2014, Neuron.
[52] Richard Nicholas,et al. Effect of high-dose simvastatin on brain atrophy and disability in secondary progressive multiple sclerosis (MS-STAT): a randomised, placebo-controlled, phase 2 trial , 2014, The Lancet.
[53] S. Strickland,et al. A novel Aβ-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer’s disease mice , 2014, The Journal of experimental medicine.
[54] A. Nimmerjahn,et al. Stepwise Recruitment of Transcellular and Paracellular Pathways Underlies Blood-Brain Barrier Breakdown in Stroke , 2014, Neuron.
[55] Jesse D. Sengillo,et al. Blood–spinal cord barrier disruption contributes to early motor-neuron degeneration in ALS-model mice , 2014, Proceedings of the National Academy of Sciences.
[56] P. Carmeliet,et al. Tissue plasminogen activator arrests Alzheimer's disease pathogenesis , 2014, Neurobiology of Aging.
[57] Liping Tang,et al. Optical imaging of fibrin deposition to elucidate participation of mast cells in foreign body responses. , 2014, Biomaterials.
[58] R. Tsien,et al. Early detection of thrombin activity in neuroinflammatory disease , 2014, Annals of neurology.
[59] P. Taylor,et al. Integrin CD11b positively regulates TLR4-induced signalling pathways in dendritic cells but not in macrophages , 2014, Nature Communications.
[60] Hilkka Soininen,et al. Prognostic polypeptide blood plasma biomarkers of Alzheimer's disease progression. , 2014, Journal of Alzheimer's disease : JAD.
[61] C. Iadecola,et al. The Pathobiology of Vascular Dementia , 2013, Neuron.
[62] C. Creighton,et al. Cleavage of Fibrinogen by Proteinases Elicits Allergic Responses Through Toll-Like Receptor 4 , 2013, Science.
[63] Protective effects of Batroxobin on spinal cord injury in rats , 2013, Neuroscience Bulletin.
[64] D. Reich,et al. Initial investigation of the blood-brain barrier in MS lesions at 7 tesla , 2013, Multiple sclerosis.
[65] S. Strickland,et al. The APOE ε4/ε4 Genotype Potentiates Vascular Fibrin(Ogen) Deposition in Amyloid-Laden Vessels in the Brains of Alzheimer's Disease Patients , 2013, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[66] Mahlon D. Johnson,et al. Deficiency in Mural Vascular Cells Coincides with Blood–Brain Barrier Disruption in Alzheimer's Disease , 2013, Brain pathology.
[67] L. Tran,et al. Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease , 2013, Cell.
[68] P. Grammas,et al. Thrombin, a mediator of cerebrovascular inflammation in AD and hypoxia , 2013, Front. Aging Neurosci..
[69] M. Turner,et al. Inflammation and neurovascular changes in amyotrophic lateral sclerosis , 2013, Molecular and Cellular Neuroscience.
[70] A. Singleton,et al. TREM2 variants in Alzheimer's disease. , 2013, The New England journal of medicine.
[71] A. Hofman,et al. Variant of TREM2 associated with the risk of Alzheimer's disease. , 2013, The New England journal of medicine.
[72] R. Tsien,et al. Ratiometric Activatable Cell-Penetrating Peptides Provide Rapid In Vivo Readout of Thrombin Activation** , 2012, Angewandte Chemie.
[73] R. Doolittle,et al. Correlating structure and function during the evolution of fibrinogen‐related domains , 2012, Protein science : a publication of the Protein Society.
[74] T. Deerinck,et al. Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation , 2012, Nature Communications.
[75] Jesse D. Sengillo,et al. Blood–spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis , 2012, Acta Neuropathologica.
[76] A. Pisani,et al. Increased blood-cerebrospinal fluid transfer of albumin in advanced Parkinson’s disease , 2012, Journal of Neuroinflammation.
[77] R. Tsien,et al. In vivo fluorescence imaging of atherosclerotic plaques with activatable cell-penetrating peptides targeting thrombin activity. , 2012, Integrative biology : quantitative biosciences from nano to macro.
[78] R. Tsien,et al. Thrombin Activity Associated with Neuronal Damage during Acute Focal Ischemia , 2012, The Journal of Neuroscience.
[79] Berislav V. Zlokovic,et al. Apolipoprotein E controls cerebrovascular integrity via cyclophilin A , 2012, Nature.
[80] S. Strickland,et al. Aβ delays fibrin clot lysis by altering fibrin structure and attenuating plasminogen binding to fibrin. , 2012, Blood.
[81] L. Mucke,et al. Alzheimer Mechanisms and Therapeutic Strategies , 2012, Cell.
[82] I. Mikhailenko,et al. Identification of VLDLR as a novel endothelial cell receptor for fibrin that modulates fibrin-dependent transendothelial migration of leukocytes. , 2012, Blood.
[83] P. Scheltens,et al. Dementia in 2011: Microbleeds in dementia—singing a different ARIA , 2012, Nature Reviews Neurology.
[84] Christophe Lemetre,et al. Identification of SPARC-like 1 protein as part of a biomarker panel for Alzheimer's disease in cerebrospinal fluid. , 2012, Journal of Alzheimer's disease : JAD.
[85] Yi Zhang,et al. Plasma Biomarkers of Brain Atrophy in Alzheimer's Disease , 2011, PloS one.
[86] B. Zlokovic. Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders , 2011, Nature Reviews Neuroscience.
[87] J. Szmydynger-Chodobska,et al. Blood–Brain Barrier Pathophysiology in Traumatic Brain Injury , 2011, Translational Stroke Research.
[88] K. M. Baeten,et al. Extracellular matrix and matrix receptors in blood–brain barrier formation and stroke , 2011, Developmental neurobiology.
[89] S. Liebner,et al. Current concepts of blood-brain barrier development. , 2011, The International journal of developmental biology.
[90] Daniel S Reich,et al. Evolution of the blood–brain barrier in newly forming multiple sclerosis lesions , 2011, Annals of neurology.
[91] D. Rowitch,et al. Myelin regeneration: a recapitulation of development? , 2011, Annual review of neuroscience.
[92] R. Tucker,et al. Tenascins and the importance of adhesion modulation. , 2011, Cold Spring Harbor perspectives in biology.
[93] Chengjie Xiong,et al. Multiplexed Immunoassay Panel Identifies Novel CSF Biomarkers for Alzheimer's Disease Diagnosis and Prognosis , 2011, PloS one.
[94] S. Lord,et al. Molecular Mechanisms Affecting Fibrin Structure and Stability , 2011, Arteriosclerosis, thrombosis, and vascular biology.
[95] D. Davalos,et al. Fibrinogen as a key regulator of inflammation in disease , 2011, Seminars in Immunopathology.
[96] Yang Yang,et al. Fibrinogen Depleting Agent Batroxobin has a Beneficial Effect on Experimental Autoimmune Encephalomyelitis , 2011, Cellular and Molecular Neurobiology.
[97] Bengt R. Johansson,et al. Pericytes regulate the blood–brain barrier , 2010, Nature.
[98] S. Strickland,et al. Alzheimer's disease peptide β-amyloid interacts with fibrinogen and induces its oligomerization , 2010, Proceedings of the National Academy of Sciences.
[99] Si-Ming Zhang,et al. The Primary Role of Fibrinogen-Related Proteins in Invertebrates Is Defense, Not Coagulation , 2010, Journal of Innate Immunity.
[100] Berislav V. Zlokovic,et al. Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging , 2010, Neuron.
[101] M. Verbeek,et al. Enoxaparin treatment administered at both early and late stages of amyloid β deposition improves cognition of APPswe/PS1dE9 mice with differential effects on brain Aβ levels , 2010, Neurobiology of Disease.
[102] Nan Li,et al. Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b , 2010, Nature Immunology.
[103] Alon Friedman,et al. Blood–brain barrier breakdown as a therapeutic target in traumatic brain injury , 2010, Nature Reviews Neurology.
[104] S. Strickland,et al. Fibrinogen and β-Amyloid Association Alters Thrombosis and Fibrinolysis: A Possible Contributing Factor to Alzheimer's Disease , 2010, Neuron.
[105] P. Tam,et al. Extrinsic regulation of pluripotent stem cells , 2010, Nature.
[106] C. Schachtrup,et al. Fibrinogen Triggers Astrocyte Scar Formation by Promoting the Availability of Active TGF-β after Vascular Damage , 2010, The Journal of Neuroscience.
[107] Carson K. Lam,et al. Embolus extravasation is an alternative mechanism for cerebral microvascular recanalization , 2010, Nature.
[108] P. Knaus,et al. BMPs: From Bone to Body Morphogenetic Proteins , 2010, Science Signaling.
[109] J. Ryu,et al. A leaky blood–brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer’s disease brain , 2008, Journal of cellular and molecular medicine.
[110] E. Haacke,et al. Serial susceptibility weighted MRI measures brain iron and microbleeds in dementia. , 2009, Journal of Alzheimer's disease : JAD.
[111] Robin J. M. Franklin,et al. Remyelination in the CNS: from biology to therapy , 2008, Nature Reviews Neuroscience.
[112] J. Ryu,et al. Relevance of Aβ 1-42 Intrahippocampal Injection as An Animal Model of Inflamed Alzheimers Disease Brain , 2008 .
[113] G. Comi,et al. The extracellular matrix affects axonal regeneration in peripheral neuropathies , 2008, Neurology.
[114] Peter Caravan,et al. EP-2104R: a fibrin-specific gadolinium-Based MRI contrast agent for detection of thrombus. , 2008, Journal of the American Chemical Society.
[115] D. Bennett,et al. LONG-TERM FETAL CELL TRANSPLANT IN HUNTINGTON DISEASE: STAYIN’ ALIVE , 2007, Neurology.
[116] Sergio E. Baranzini,et al. Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets , 2008, Nature.
[117] B. Zlokovic. The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders , 2008, Neuron.
[118] G. Xu,et al. Plasma fibrinogen is associated with cognitive decline and risk for dementia in patients with mild cognitive impairment , 2007, International journal of clinical practice.
[119] I. Shelef,et al. Blood–brain barrier disruption in post-traumatic epilepsy , 2007, Journal of Neurology, Neurosurgery, and Psychiatry.
[120] H. Lassmann,et al. Lesion genesis in a subset of patients with multiple sclerosis: a role for innate immunity? , 2007, Brain : a journal of neurology.
[121] I. Tsigelny,et al. Fibrinogen signal transduction as a mediator and therapeutic target in inflammation: lessons from multiple sclerosis. , 2007, Current medicinal chemistry.
[122] J. Melchor,et al. Fibrin deposition accelerates neurovascular damage and neuroinflammation in mouse models of Alzheimer's disease. , 2007 .
[123] Benjamin D. Sachs,et al. Fibrinogen inhibits neurite outgrowth via β3 integrin-mediated phosphorylation of the EGF receptor , 2007, Proceedings of the National Academy of Sciences.
[124] Benjamin D. Sachs,et al. p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway , 2007, The Journal of cell biology.
[125] S. Ha,et al. Fibrinogen gamma-A chain precursor in CSF: a candidate biomarker for Alzheimer's disease , 2007, BMC neurology.
[126] J. Kaye,et al. Blood–brain barrier impairment in Alzheimer disease , 2007, Neurology.
[127] H. Lassmann,et al. The fibrin-derived γ377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease , 2007, The Journal of experimental medicine.
[128] M. Pepys,et al. Human plasma fibrinogen is synthesized in the liver. , 2007, Blood.
[129] S. McQuaid,et al. Persistent endothelial abnormalities and blood–brain barrier leak in primary and secondary progressive multiple sclerosis , 2007, Neuropathology and applied neurobiology.
[130] Jonathan Stone,et al. Microvascular pathology in the aging human brain: Evidence that senile plaques are sites of microhaemorrhages , 2006, Neurobiology of Aging.
[131] B. Lipiński,et al. New insight into Alzheimer disease: demonstration of fibrin(ogen)-serum albumin insoluble deposits in brain tissue. , 2006, Alzheimer disease and associated disorders.
[132] B. Engelhardt,et al. Dysferlin Is a New Marker for Leaky Brain Blood Vessels in Multiple Sclerosis , 2006, Journal of neuropathology and experimental neurology.
[133] P. Oschmann,et al. The impact of interferon-β treatment on the blood-brain barrier , 2006 .
[134] P. Duquette,et al. Statins reduce human blood–brain barrier permeability and restrict leukocyte migration: Relevance to multiple sclerosis , 2006, Annals of neurology.
[135] P. Koolwijk,et al. Fibrin structure and wound healing , 2006, Journal of thrombosis and haemostasis : JTH.
[136] S. Strickland,et al. Exogenous Tissue Plasminogen Activator Enhances Peripheral Nerve Regeneration and Functional Recovery After Injury In Mice , 2006, Journal of neuropathology and experimental neurology.
[137] E. Hansson,et al. Astrocyte–endothelial interactions at the blood–brain barrier , 2006, Nature Reviews Neuroscience.
[138] F. Barkhof,et al. Blood–brain barrier alterations in both focal and diffuse abnormalities on postmortem MRI in multiple sclerosis , 2005, Neurobiology of Disease.
[139] Albert Hofman,et al. Fibrinogen Is Associated With an Increased Risk of Alzheimer Disease and Vascular Dementia , 2005, Stroke.
[140] M. Mosesson. Fibrinogen and fibrin structure and functions , 2005, Journal of thrombosis and haemostasis : JTH.
[141] Hans Lassmann,et al. Multiple Sclerosis Pathology: Evolution of Pathogenetic Concepts , 2005, Brain pathology.
[142] J. Bart,et al. Blood–brain barrier dysfunction in parkinsonian midbrain in vivo , 2005, Annals of neurology.
[143] R. Pascual-Marqui,et al. Focal Cortical Dysfunction and Blood–Brain Barrier Disruption in Patients With Postconcussion Syndrome , 2005, Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.
[144] Dr. Eduard Rindfleisch,et al. Histologisches Detail zu der grauen Degeneration von Gehirn und Rückenmark. (Zugleich ein Beitrag zu der Lehre von der Entstehung und Verwandlung der Zelle.) , 1863, Archiv für pathologische Anatomie und Physiologie und für klinische Medicin.
[145] J. Degen,et al. Fibrin(ogen)-αMβ2 Interactions Regulate Leukocyte Function and Innate Immunity In Vivo , 2004 .
[146] M. Alessio,et al. Proteome study of human cerebrospinal fluid following traumatic brain injury indicates fibrin(ogen) degradation products as trauma-associated markers. , 2004, Journal of neurotrauma.
[147] J. Golden,et al. Oligodendrocyte maturation is inhibited by bone morphogenetic protein , 2004, Molecular and Cellular Neuroscience.
[148] N. Reiner,et al. Dual Receptors and Distinct Pathways Mediate Interleukin-1 Receptor-associated Kinase Degradation in Response to Lipopolysaccharide , 2004, Journal of Biological Chemistry.
[149] Benjamin D. Sachs,et al. Fibrin mechanisms and functions in nervous system pathology. , 2004, Molecular interventions.
[150] D. Witte,et al. Leukocyte engagement of fibrin(ogen) via the integrin receptor αMβ2/Mac-1 is critical for host inflammatory response in vivo , 2004 .
[151] C. Vergani,et al. Peripheral Treatment with Enoxaparin, a Low Molecular Weight Heparin, Reduces Plaques and β-Amyloid Accumulation in a Mouse Model of Alzheimer's Disease , 2004, The Journal of Neuroscience.
[152] H. Lassmann,et al. Fibrin depletion decreases inflammation and delays the onset of demyelination in a tumor necrosis factor transgenic mouse model for multiple sclerosis. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[153] M. Barnett,et al. Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion , 2004, Annals of neurology.
[154] C. Brosnan,et al. Evidence of persistent blood-brain barrier abnormalities in chronic-progressive multiple sclerosis , 2004, Acta Neuropathologica.
[155] D. Carey,et al. αVβ8 integrin is a Schwann cell receptor for fibrin , 2003 .
[156] D. Dickstein,et al. Blood—Brain Barrier Permeability Precedes Senile Plaque Formation in an Alzheimer Disease Model , 2003 .
[157] S. McQuaid,et al. Tight junctional abnormality in multiple sclerosis white matter affects all calibres of vessel and is associated with blood–brain barrier leakage and active demyelination , 2003, The Journal of pathology.
[158] S. Lord,et al. Sequence γ377−395(P2), but Not γ190−202(P1), Is the Binding Site for the αMI-Domain of Integrin αMβ2 in the γC-Domain of Fibrinogen† , 2003 .
[159] M. Cuzner,et al. Impaired fibrinolysis in multiple sclerosis: a role for tissue plasminogen activator inhibitors. , 2003, Brain : a journal of neurology.
[160] K. Akassoglou,et al. Fibrin is a regulator of Schwann cell migration after sciatic nerve injury in mice , 2003, Neuroscience Letters.
[161] W. Gomes,et al. Transgenic overexpression of BMP4 increases astroglial and decreases oligodendroglial lineage commitment. , 2003, Developmental biology.
[162] F. Jolesz,et al. MRI contrast uptake in new lesions in relapsing-remitting MS followed at weekly intervals , 2003, Neurology.
[163] S. Tsirka,et al. Involvement of Tissue Plasminogen Activator in Onset and Effector Phases of Experimental Allergic Encephalomyelitis , 2002, The Journal of Neuroscience.
[164] T. Ugarova,et al. Regulated Unmasking of the Cryptic Binding Site for Integrin αMβ2 in the γC-Domain of Fibrinogen† , 2002 .
[165] B. Furie,et al. Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse , 2002, Nature Medicine.
[166] M. Graves,et al. Cyclooxygenase‐2‐positive macrophages infiltrate the Alzheimer’s disease brain and damage the blood–brain barrier , 2002, European journal of clinical investigation.
[167] Pamela L. Follett,et al. The Toll-Like Receptor TLR4 Is Necessary for Lipopolysaccharide-Induced Oligodendrocyte Injury in the CNS , 2002, The Journal of Neuroscience.
[168] L. Medved,et al. Interaction of fibrin(ogen) with the endothelial cell receptor VE-cadherin: mapping of the receptor-binding site in the NH2-terminal portions of the fibrin beta chains. , 2002, Biochemistry.
[169] K. Akassoglou,et al. Fibrin Inhibits Peripheral Nerve Remyelination by Regulating Schwann Cell Differentiation , 2002, Neuron.
[170] K. Akassoglou,et al. Nervous System Pathology: The Fibrin Perspective , 2002, Biological chemistry.
[171] F. Castellino,et al. Accelerated skin wound healing in plasminogen activator inhibitor-1-deficient mice. , 2001, The American journal of pathology.
[172] J. Newcombe,et al. Plasminogen activators in multiple sclerosis lesions: implications for the inflammatory response and axonal damage. , 2001, Brain : a journal of neurology.
[173] W. Hancock,et al. Fibrinogen Stimulates Macrophage Chemokine Secretion Through Toll-Like Receptor 41 , 2001, The Journal of Immunology.
[174] G. Tsurupa,et al. Conformational Changes upon Conversion of Fibrinogen into Fibrin , 2001, Annals of the New York Academy of Sciences.
[175] C. Lucchinetti,et al. Heterogeneity of multiple sclerosis pathogenesis: implications for diagnosis and therapy. , 2001, Trends in molecular medicine.
[176] Ross L. Cagan,et al. Scabrous complexes with Notch to mediate boundary formation , 2001, Nature.
[177] S. Akira,et al. CD11b/CD18 Acts in Concert with CD14 and Toll-Like Receptor (TLR) 4 to Elicit Full Lipopolysaccharide and Taxol-Inducible Gene Expression1 2 3 , 2001, The Journal of Immunology.
[178] I. Mochalkin,et al. A model of fibrin formation based on crystal structures of fibrinogen and fibrin fragments complexed with synthetic peptides. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[179] J. Mizuguchi,et al. Fibrinogen Binds to Integrin α5β1via the Carboxyl-Terminal RGD Site of the Aα-Chain , 2000 .
[180] K. Akassoglou,et al. Tissue Plasminogen Activator–Mediated Fibrinolysis Protects against Axonal Degeneration and Demyelination after Sciatic Nerve Injury , 2000, The Journal of cell biology.
[181] White,et al. Evidence of blood–brain barrier dysfunction in human cerebral malaria , 1999, Neuropathology and applied neurobiology.
[182] Joseph J. Volpe,et al. Maturation-Dependent Vulnerability of Oligodendrocytes to Oxidative Stress-Induced Death Caused by Glutathione Depletion , 1998, The Journal of Neuroscience.
[183] C. Rüegg,et al. Characterization of human fibroleukin, a fibrinogen-like protein secreted by T lymphocytes. , 1998, Journal of immunology.
[184] L. Parnetti,et al. Activation of the Contact System in Cerebrospinal Fluid of Patients with Alzheimer Disease , 1998, Alzheimer disease and associated disorders.
[185] P. Sonderegger,et al. The Axonally Secreted Serine Proteinase Inhibitor, Neuroserpin, Inhibits Plasminogen Activators and Plasmin but Not Thrombin* , 1998, The Journal of Biological Chemistry.
[186] C. Lucchinetti,et al. Multiple sclerosis: lessons from neuropathology. , 1998, Seminars in neurology.
[187] Hans Lassmann,et al. Inflammatory central nervous system demyelination: Correlation of magnetic resonance imaging findings with lesion pathology , 1997, Annals of neurology.
[188] N. Yanagisawa,et al. Fibrin deposition in the central nervous system correlates with the degree of Theiler's murine encephalomyelitis virus-induced demyelinating disease , 1997, Journal of Neuroimmunology.
[189] M. Esiri,et al. The application of multifactorial cluster analysis in the staging of plaques in early multiple sclerosis. Identification and characterization of the primary demyelinating lesion. , 1997, Brain : a journal of neurology.
[190] N. Yanagisawa,et al. Suppression of cell-transferred experimental autoimmune encephalomyelitis in defibrinated Lewis rats , 1996, Journal of Neuroimmunology.
[191] T. Bugge,et al. Loss of Fibrinogen Rescues Mice from the Pleiotropic Effects of Plasminogen Deficiency , 1996, Cell.
[192] M. J. Danton,et al. Impaired platelet aggregation and sustained bleeding in mice lacking the fibrinogen motif bound by integrin alpha IIb beta 3. , 1996, The EMBO journal.
[193] R. Ádány,et al. Fibrin deposition in primary and metastatic human brain tumours. , 1996, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.
[194] S. Lord,et al. Dissecting Clot Retraction and Platelet Aggregation , 1996, The Journal of Biological Chemistry.
[195] L. Lund,et al. Impaired wound healing in mice with a disrupted plasminogen gene , 1996, Nature Medicine.
[196] T. Fujita,et al. A Novel Human Serum Lectin with Collagen- and Fibrinogen-like Domains That Functions as an Opsonin (*) , 1996, The Journal of Biological Chemistry.
[197] Theodore T. Suh,et al. Impaired platelet aggregation andsustained bleeding inmicelacking thefibrinogen motifbound byintegrin alIb13 , 1996 .
[198] L. Languino,et al. Structural Recognition of a Novel Fibrinogen Chain Sequence (117133) by Intercellular Adhesion Molecule-1 Mediates Leukocyte-Endothelium Interaction (*) , 1995, The Journal of Biological Chemistry.
[199] J. Prineas,et al. Blood‐Brain Barrier Abnormalities in Longstanding Multiple Sclerosis Lesions. An Immunohistochemical Study , 1994, Journal of neuropathology and experimental neurology.
[200] A. Wakefield,et al. Immunohistochemical study of vascular injury in acute multiple sclerosis. , 1994, Journal of clinical pathology.
[201] J. Taubenberger,et al. Correlation between magnetic resonance imaging findings and lesion development in chronic, active multiple sclerosis , 1993, Annals of neurology.
[202] W. S. Thomas,et al. Tissue Factor Contributes to Microvascular Defects After Focal Cerebral Ischemia , 1993, Stroke.
[203] J. Volpe,et al. Vulnerability of oligodendroglia to glutamate: pharmacology, mechanisms, and prevention , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[204] R F Doolittle,et al. A detailed consideration of a principal domain of vertebrate fibrinogen and its relatives , 1992, Protein science : a publication of the Protein Society.
[205] M. Esiri,et al. Blood-brain barrier damage in acute multiple sclerosis plaques. An immunocytological study. , 1991, Brain : a journal of neurology.
[206] B E Kendall,et al. Breakdown of the blood-brain barrier precedes symptoms and other MRI signs of new lesions in multiple sclerosis. Pathogenetic and clinical implications. , 1990, Brain : a journal of neurology.
[207] D. Cheresh,et al. Interaction of integrins alpha v beta 3 and glycoprotein IIb-IIIa with fibrinogen. Differential peptide recognition accounts for distinct binding sites. , 1990, The Journal of biological chemistry.
[208] H I Goldberg,et al. Multiple sclerosis: serial study of gadolinium-enhanced MR imaging. , 1988, Radiology.
[209] B E Kendall,et al. Serial gadolinium enhanced magnetic resonance imaging in multiple sclerosis. , 1988, Brain : a journal of neurology.
[210] R. Doolittle. Fibrinogen and fibrin. , 1981, Scientific American.
[211] E. Engvall,et al. Affinity of fibronectin to collagens of different genetic types and to fibrinogen , 1978, The Journal of experimental medicine.
[212] Paterson Py. Experimental allergic encephalomyelitis: role of fibrin deposition in immunopathogenesis of inflammation in rats. , 1976, Federation proceedings.
[213] P. Y. Paterson. Experimental allergic encephalomyelitis: role of fibrin deposition in immunopathogenesis of inflammation in rats. , 1976, Federation proceedings.
[214] Fanny Marhuenda,et al. CONTACTS , 1967 .
[215] W. L. Benedict,et al. Multiple Sclerosis , 2007, Journal - Michigan State Medical Society.
[216] R. Adams,et al. The morbid anatomy of the demyelinative diseases , 1952 .
[217] R. D. Adams,et al. The morbid anatomy of the demyelinative disease. , 1952, American Journal of Medicine.