Computed tomography-osteoabsorptiometry for assessing the density distribution of subchondral bone as a measure of long-term mechanical adaptation in individual joints

To estimate subchondral mineralisation patterns which represent the long-term loading history of individual joints, a method has been developed employing computed tomography (CT) which permits repeated examination of living joints. The method was tested on 5 knee, 3 sacroiliac, 3 ankle and 5 shoulder joints and then investigated with X-ray densitometry. A CT absorptiometric presentation and maps of the area distribution of the subchondral bone density areas were derived using an image analyser. Comparison of the results from both X-ray densitometry and CT-absorptiometry revealed almost identical pictures of distribution of the subchondral bone density. The method may be used to examine subchondral mineralisation as a measure of the mechanical adaptability of joints in the living subject.

[1]  Benno Kummer,et al.  Die Beanspruchung des menschlichen Hftgelenks@@@The stress of the human hip joint: I. Allgemeine Problematik@@@I. General problems , 1968 .

[2]  Nicholas M. Spyrou,et al.  Imaging with ionizing radiations , 1982 .

[3]  P G Maquet,et al.  Femorotibial weight-bearing areas. Experimental determination. , 1975, The Journal of bone and joint surgery. American volume.

[4]  H. Genant,et al.  Quantitative bone mineral analysis using dual energy computed tomography. , 1977, Investigative radiology.

[5]  G U Rao,et al.  Systematic errors in bone-mineral measurements by quantitative computed tomography. , 1987, Medical physics.

[6]  A. Schleicher,et al.  Quantitative analysis of x-ray images with a television image analyser. , 1980, Microscopica acta.

[7]  K. Alexander,et al.  Studies of tibial subchondral bone density and its significance. , 1985, The Journal of bone and joint surgery. American volume.

[8]  Dr. med. h. c. Dr. Ing. E. h. Professor Friedrich Pauwels Dr. med. Biomechanics of the Locomotor Apparatus , 1980, Springer Berlin Heidelberg.

[9]  J. Knief Materialverteilung und Beanspruchungsverteilung im coxalen Femurende , 1967, Zeitschrift für Anatomie und Entwicklungsgeschichte.

[10]  W. Kalender,et al.  Evaluation of a prototype dual-energy computed tomographic apparatus. I. Phantom studies. , 1986, Medical physics.

[11]  P S Walker,et al.  Adaptive changes in the femur after implantation of an Austin Moore prosthesis. , 1984, The Journal of bone and joint surgery. American volume.

[12]  J. Adams,et al.  Measurement of Trabecular Bone Mineral by Dual Energy Computed Tomography , 1982, Journal of computer assisted tomography.

[13]  H. Konermann Quantitative Bestimmung der Materialverteilung nach Röntgenbildern des Knochens mit einer neuen fotografischen Methode , 2004, Zeitschrift für Anatomie und Entwicklungsgeschichte.

[14]  I. Hvid,et al.  Density changes at the proximal tibia after medial meniscectomy , 1989, Journal of Orthopaedic Research.

[15]  H. E. Meema,et al.  A METHOD FOR DETERMINATION OF BONE-SALT CONTENT OF CORTICAL BONE. , 1964, Radiology.

[16]  Hartmut Molzberger Die Beanspruchung des menschlichen Hüftgelenks , 1973, Zeitschrift für Anatomie und Entwicklungsgeschichte.