Renal fibrosis is not reduced by blocking transforming growth factor-β signaling in matrix-producing interstitial cells
暂无分享,去创建一个
R. Harris | C. Hao | A. Fogo | R. Zent | Haichun Yang | Leslie S. Gewin | Surekha Neelisetty | Catherine E. Alford | Karen Reynolds | Luke G. Woodbury | Stellor Nlandu-khodo | Stellor Nlandu-Khodo | L. Gewin | Raymond C. Harris | Luke Woodbury
[1] C. Hao,et al. Generation of a Tenascin-C-CreER2 Knockin Mouse Line for Conditional DNA Recombination in Renal Medullary Interstitial Cells , 2013, PloS one.
[2] Liqun He,et al. Adiponectin promotes monocyte-to-fibroblast transition in renal fibrosis. , 2013, Journal of the American Society of Nephrology : JASN.
[3] A. McMahon,et al. Wnt4/β-catenin signaling in medullary kidney myofibroblasts. , 2013, Journal of the American Society of Nephrology : JASN.
[4] R. Kalluri,et al. Origin and function of myofibroblasts in kidney fibrosis , 2013, Nature Medicine.
[5] Eric P. Skaar,et al. Cdc42 Promotes Host Defenses against Fatal Infection , 2013, Infection and Immunity.
[6] B. Thornhill,et al. Transforming growth factor-β1 receptor inhibition preserves glomerulotubular integrity during ureteral obstruction in adults but worsens injury in neonatal mice. , 2013, American journal of physiology. Renal physiology.
[7] Linghong Huang,et al. Development of a Chronic Kidney Disease Model in C57BL/6 Mice with Relevance to Human Pathology , 2013, Nephron Extra.
[8] P. Boor,et al. The renal (myo-)fibroblast: a heterogeneous group of cells. , 2012, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
[9] Yi-Pu Chen,et al. JNK-dependent AP-1 activation is required for aristolochic acid-induced TGF-β1 synthesis in human renal proximal epithelial cells. , 2012, American journal of physiology. Renal physiology.
[10] J. Duffield,et al. Platelet-derived growth factor receptor signaling activates pericyte-myofibroblast transition in obstructive and post-ischemic kidney fibrosis. , 2011, Kidney international.
[11] R. Mason,et al. Interstitial fibrosis is associated with increased COL1A2 transcription in AA-injured renal tubular epithelial cells in vivo. , 2011, Matrix biology : journal of the International Society for Matrix Biology.
[12] P. Boor,et al. Renal fibrosis: novel insights into mechanisms and therapeutic targets , 2010, Nature Reviews Nephrology.
[13] A. Pozzi,et al. TGF-beta receptor deletion in the renal collecting system exacerbates fibrosis. , 2010, Journal of the American Society of Nephrology : JASN.
[14] H. Yasumo,et al. A sensitive short-term evaluation of antifibrotic effects using newly established type I collagen reporter transgenic rats. , 2010, American journal of physiology. Renal physiology.
[15] L. Casteilla,et al. Human Fibroblasts Share Immunosuppressive Properties with Bone Marrow Mesenchymal Stem Cells , 2010, Journal of Clinical Immunology.
[16] K. Lai,et al. Mechanism of chronic aristolochic acid nephropathy: role of Smad3. , 2010, American journal of physiology. Renal physiology.
[17] B. Hinz. The myofibroblast: paradigm for a mechanically active cell. , 2010, Journal of biomechanics.
[18] M. Le Hir,et al. The renal cortical interstitium: morphological and functional aspects , 2008, Histochemistry and Cell Biology.
[19] Jing-zi Li,et al. Connective tissue growth factor stimulates renal cortical myofibroblast‐like cell proliferation and matrix protein production , 2008, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.
[20] L. Luo,et al. A global double‐fluorescent Cre reporter mouse , 2007, Genesis.
[21] R. Poulsom,et al. Bone marrow-derived cells do not contribute significantly to collagen I synthesis in a murine model of renal fibrosis. , 2006, Journal of the American Society of Nephrology : JASN.
[22] D. Häussinger,et al. Differential and Synergistic Effects of Platelet-derived Growth Factor-BB and Transforming Growth Factor-β1 on Activated Pancreatic Stellate Cells , 2005, Pancreas.
[23] M. Le Hir,et al. Antibodies against macrophages that overlap in specificity with fibroblasts. , 2005, Kidney international.
[24] D. Brenner,et al. A dual reporter gene transgenic mouse demonstrates heterogeneity in hepatic fibrogenic cell populations , 2004, Hepatology.
[25] David Botstein,et al. Diversity, topographic differentiation, and positional memory in human fibroblasts , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[26] M. Rastaldi,et al. Epithelial-mesenchymal transition of tubular epithelial cells in human renal biopsies. , 2002, Kidney international.
[27] C. Denton,et al. Ligand-dependent genetic recombination in fibroblasts : a potentially powerful technique for investigating gene function in fibrosis. , 2002, The American journal of pathology.
[28] B. Hinz,et al. Myofibroblasts and mechano-regulation of connective tissue remodelling , 2002, Nature Reviews Molecular Cell Biology.
[29] Andrew P McMahon,et al. Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse. , 2002, Developmental biology.
[30] H. Moses,et al. Conditional inactivation of the TGF‐β type II receptor using Cre:Lox , 2002, Genesis.
[31] G. Müller,et al. A novel model to study renal myofibroblast formation in vitro. , 2001, Kidney international.
[32] D. Poppas,et al. Antibody to transforming growth factor-beta ameliorates tubular apoptosis in unilateral ureteral obstruction. , 2000, Kidney international.
[33] S. Nagao,et al. Progressive renal fibrosis in murine polycystic kidney disease: an immunohistochemical observation. , 2000, Kidney international.
[34] K. Sharma,et al. Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[35] K. Niederreither,et al. A potent far-upstream enhancer in the mouse pro alpha 2(I) collagen gene regulates expression of reporter genes in transgenic mice , 1996, The Journal of cell biology.
[36] J. Loffing,et al. Morphology of interstitial cells in the healthy kidney , 1996, Anatomy and Embryology.
[37] K. Miyazono,et al. Formation of hetero-oligomeric complexes of type I and type II receptors for transforming growth factor-beta. , 1994, The Journal of biological chemistry.
[38] A. Geinoz,et al. Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts , 1993, The Journal of cell biology.
[39] M. Le Hir,et al. Distribution and regulation of renal ecto-5'-nucleotidase: implications for physiological functions of adenosine. , 1993, The American journal of physiology.
[40] Jeffrey L. Wrana,et al. TGFβ signals through a heteromeric protein kinase receptor complex , 1992, Cell.
[41] M. Enger,et al. TGFβ elicits opposite responses in clonal subpopulations of NRK-49F cells , 1991 .
[42] P. Ekblom,et al. Stimulation of tenascin expression in mesenchyme by epithelial-mesenchymal interactions. , 1989, The International journal of developmental biology.
[43] J. Massagué,et al. Regulation of fibronectin and type I collagen mRNA levels by transforming growth factor-beta. , 1987, The Journal of biological chemistry.
[44] M. Sporn,et al. Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[45] J. Duffield,et al. Transforming Growth Factor b-1 Stimulates Pro fi brotic Epithelial Signaling to Activate Pericyte-Myo fi broblast Transition in Obstructive Kidney Fibrosis , 2012 .
[46] R. Gebhardt,et al. Cardiovascular , Pulmonary and Renal Pathology Tubular Overexpression of Transforming Growth Factor-1 Induces Autophagy and Fibrosis but Not Mesenchymal Transition of Renal Epithelial Cells , 2010 .
[47] D. Brenner,et al. Epithelial and Mesenchymal Cell Biology Pericytes and Perivascular Fibroblasts Are the Primary Source of Collagen-Producing Cells in Obstructive Fibrosis of the Kidney , 2010 .
[48] Ying E Zhang,et al. Non-Smad pathways in TGF-β signaling , 2009, Cell Research.
[49] A. Pozzi,et al. Divergent effects of low versus high dose anti-TGF-beta antibody in puromycin aminonucleoside nephropathy in rats. , 2004, Kidney international.
[50] L. Truong,et al. Tenascin is an ubiquitous extracellular matrix protein of human renal interstitium in normal and pathologic conditions. , 1996, Nephron.
[51] T. Haverty,et al. Biosynthetic and proliferative characteristics of tubulointerstitial fibroblasts probed with paracrine cytokines. , 1992, Kidney international.
[52] L. Truong,et al. J Am Soc Nephrol 14: 2544–2555, 2003 Obstructive Uropathy in Mice and Humans: Potential Role for PDGF-D in the Progression of Tubulointerstitial Injury , 2022 .