General solution for quantitative dark-field contrast imaging with grating interferometers

Grating interferometer based imaging with X-rays and neutrons has proven to hold huge potential for applications in key research fields conveying biology and medicine as well as engineering and magnetism, respectively. The thereby amenable dark-field imaging modality implied the promise to access structural information beyond reach of direct spatial resolution. However, only here a yet missing approach is reported that finally allows exploiting this outstanding potential for non-destructive materials characterizations. It enables to obtain quantitative structural small angle scattering information combined with up to 3-dimensional spatial image resolution even at lab based x-ray or at neutron sources. The implied two orders of magnitude efficiency gain as compared to currently available techniques in this regime paves the way for unprecedented structural investigations of complex sample systems of interest for material science in a vast range of fields.

[1]  U. Bonse,et al.  TAILLESS X‐RAY SINGLE‐CRYSTAL REFLECTION CURVES OBTAINED BY MULTIPLE REFLECTION , 1965 .

[2]  P ? ? ? ? ? ? ? % ? ? ? ? , 1991 .

[3]  C. David,et al.  Three-dimensional imaging of magnetic domains. , 2010, Nature communications.

[4]  Ashley F. Stein,et al.  Interpretation of dark-field contrast and particle-size selectivity in grating interferometers. , 2011, Applied optics.

[5]  Han Wen,et al.  Fourier X-ray scattering radiography yields bone structural information. , 2009, Radiology.

[6]  Wim G. Bouwman,et al.  Analysis of spin-echo small-angle neutron scattering measurements , 2008 .

[7]  Gang Li,et al.  Attempt at Visualizing Breast Cancer with X-ray Dark Field Imaging , 2005 .

[8]  S. Komura,et al.  [Neutron spin echo]. , 1985, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme.

[9]  R Bellotti,et al.  Imaging the ultrasmall-angle x-ray scattering distribution with grating interferometry. , 2012, Physical review letters.

[10]  良二 上田.  J. Appl. Cryst.の発刊に際して , 1970 .

[11]  M. Theo Rekveldt,et al.  Novel SANS instrument using Neutron Spin Echo , 1996 .

[12]  O. Bunk,et al.  Hard-X-ray dark-field imaging using a grating interferometer. , 2008, Nature materials.

[13]  Franz Pfeiffer,et al.  Inverse geometry for grating-based x-ray phase-contrast imaging , 2009 .

[14]  D. I. Svergun,et al.  Structure Analysis by Small-Angle X-Ray and Neutron Scattering , 1987 .

[15]  C. David,et al.  The First Analysis and Clinical Evaluation of Native Breast Tissue Using Differential Phase-Contrast Mammography , 2011, Investigative radiology.

[16]  Franz Pfeiffer,et al.  Visualizing the propagation of volume magnetization in bulk ferromagnetic materials by neutron grating interferometry (invited) , 2010 .

[17]  Marco Stampanoni,et al.  Toward clinical differential phase contrast mammography: preliminary evaluations and image processing schemes , 2013 .

[18]  Franz Pfeiffer,et al.  Emphysema diagnosis using X-ray dark-field imaging at a laser-driven compact synchrotron light source , 2012, Proceedings of the National Academy of Sciences.

[19]  Franz Pfeiffer,et al.  Brain tumor imaging using small-angle x-ray scattering tomography , 2011, Physics in medicine and biology.

[20]  Atsushi Momose,et al.  Distribution of unresolvable anisotropic microstructures revealed in visibility-contrast images using x-ray Talbot interferometry , 2011 .

[21]  André Hilger,et al.  Small angle scattering signals for (neutron) computerized tomography , 2004 .

[22]  O. Bunk,et al.  Neutron phase imaging and tomography. , 2006, Physical review letters.

[23]  Andrew G. Glen,et al.  APPL , 2001 .

[24]  John B. Shoven,et al.  I , Edinburgh Medical and Surgical Journal.

[25]  Franz Pfeiffer,et al.  Quantitative x-ray dark-field computed tomography , 2010, Physics in medicine and biology.

[26]  Franz Pfeiffer,et al.  Directional x-ray dark-field imaging , 2010, Physics in medicine and biology.

[27]  Sabrina S Wilson.  Radiology , 1938, Glasgow Medical Journal.

[28]  A. Momose,et al.  On the origin of visibility contrast in x-ray Talbot interferometry. , 2010, Optics express.

[29]  Boris Khaykovich,et al.  Demonstration of a novel focusing small-angle neutron scattering instrument equipped with axisymmetric mirrors , 2013, Nature Communications.

[30]  Franz Pfeiffer,et al.  Directional x-ray dark-field imaging of strongly ordered systems , 2010 .

[31]  Nikolay Kardjilov,et al.  TOF-SEMSANS—Time-of-flight spin-echo modulated small-angle neutron scattering , 2012 .

[32]  Nikolay Kardjilov,et al.  Observation of Magnetic Domains in Insulation-Coated Electrical Steels by Neutron Dark-Field Imaging , 2010 .

[33]  Michele Maggiore,et al.  Theory and experiments , 2008 .

[34]  Franz Pfeiffer,et al.  Bulk magnetic domain structures visualized by neutron dark-field imaging , 2008 .

[35]  Franz Pfeiffer,et al.  Quantification of the neutron dark-field imaging signal in grating interferometry , 2013 .

[36]  John Banhart,et al.  Revealing microstructural inhomogeneities with dark-field neutron imaging , 2010 .

[37]  F. Pfeiffer,et al.  Neutron dark-field tomography. , 2008, Physical review letters.

[38]  Wim G. Bouwman,et al.  Real-space interpretation of spin-echo small-angle neutron scattering , 2003 .

[39]  Franz Pfeiffer,et al.  Quantitative wave-optical numerical analysis of the dark-field signal in grating-based X-ray interferometry , 2012 .

[40]  O. Uca,et al.  Line integral corrections in spin-echo small angle neutron scattering instrument , 2001 .

[41]  Timm Weitkamp,et al.  X-ray vector radiography for bone micro-architecture diagnostics , 2012, Physics in medicine and biology.

[42]  O. Bunk,et al.  Phase retrieval and differential phase-contrast imaging with low-brilliance X-ray sources , 2006 .

[43]  Kejun Kang,et al.  Quantitative grating-based x-ray dark-field computed tomography , 2009 .

[44]  R. Lathe.  Phd by thesis , 1988, Nature.

[45]  J. Banhart.  Advanced tomographic methods in materials research and engineering , 2008 .