Furin Targeted Drug Delivery for Treatment of Rhabdomyosarcoma in a Mouse Model
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Michele Bernasconi | B. Schäfer | F. Niggli | M. Bernasconi | Katarina Hajdin | Valentina D'Alessandro | Felix K. Niggli | Beat W. Schäfer | Katarina Hajdin | V. D’alessandro | V. D'alessandro | Michele Bernasconi
[1] E. Ruoslahti,et al. Vascular zip codes in angiogenesis and metastasis. , 2004, Biochemical Society transactions.
[2] N. Seidah,et al. Evidence that furin is an authentic transforming growth factor-beta1-converting enzyme. , 2001, The American journal of pathology.
[3] A. Strongin,et al. Selective and potent furin inhibitors protect cells from anthrax without significant toxicity. , 2010, The international journal of biochemistry & cell biology.
[4] Fabien Calvo,et al. Opposing function of the proprotein convertases furin and PACE4 on breast cancer cells' malignant phenotypes: role of tissue inhibitors of metalloproteinase-1. , 2007, Cancer research.
[5] C. Dubois,et al. Furin gene (fur) regulation in differentiating human megakaryoblastic Dami cells: involvement of the proximal GATA recognition motif in the P1 promoter and impact on the maturation of furin substrates. , 2002, Blood.
[6] R. Herrmann,et al. Overview of monoclonal antibodies in cancer therapy: present and promise. , 2005, Critical reviews in oncology/hematology.
[7] R. Leduc,et al. Subtilase-like pro-protein convertases: from molecular specificity to therapeutic applications. , 2000, Journal of molecular endocrinology.
[8] K. Alitalo,et al. Proprotein convertases promote processing of VEGF‐D, a critical step for binding the angiogenic receptor VEGFR‐2 , 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[9] C Di Bello,et al. Identification of the Paired Basic Convertases Implicated in HIV gp160 Processing Based on in Vitro Assays and Expression in CD4+ Cell Lines* , 1996, The Journal of Biological Chemistry.
[10] W. Arap,et al. Combinatorial Targeting of the Macropinocytotic Pathway in Leukemia and Lymphoma Cells* , 2008, Journal of Biological Chemistry.
[11] S. Takahashi,et al. A Second Mutant Allele of Furin in the Processing-incompetent Cell Line, LoVo , 1995, The Journal of Biological Chemistry.
[12] P. Lollini,et al. Molecular and cellular biology of rhabdomyosarcoma. , 2009, Future oncology.
[13] W. Meyer,et al. Rhabdomyosarcoma: new windows of opportunity. , 2005, The oncologist.
[14] G. Thomas,et al. alpha1-Antitrypsin Portland, a bioengineered serpin highly selective for furin: application as an antipathogenic agent. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[15] A. Basak,et al. A Novel Enediynyl Peptide Inhibitor of Furin That Blocks Processing of proPDGF-A, B and proVEGF-C , 2009, PloS one.
[16] B. Schäfer,et al. Molecular features of a human rhabdomyosarcoma cell line with spontaneous metastatic progression , 2000, British Journal of Cancer.
[17] N. Katunuma,et al. Processing protease for gp160 human immunodeficiency virus type I envelope glycoprotein precursor in human T4+ lymphocytes. Purification and characterization. , 1993, The Journal of biological chemistry.
[18] Erkki Ruoslahti,et al. Mitochondrial/cell-surface protein p32/gC1qR as a molecular target in tumor cells and tumor stroma. , 2008, Cancer research.
[19] S. Futaki. Oligoarginine vectors for intracellular delivery: design and cellular-uptake mechanisms. , 2006, Biopolymers.
[20] E. Fleck,et al. Proprotein convertases regulate insulin-like growth factor 1-induced membrane-type 1 matrix metalloproteinase in VSMCs via endoproteolytic activation of the insulin-like growth factor-1 receptor. , 2004, Biochemical and biophysical research communications.
[21] Erkki Ruoslahti,et al. Tissue-penetrating delivery of compounds and nanoparticles into tumors. , 2009, Cancer cell.
[22] D. Bassi,et al. Proprotein convertases: “Master switches” in the regulation of tumor growth and progression , 2005, Molecular carcinogenesis.
[23] N. Seidah,et al. The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis. , 2003, The Journal of clinical investigation.
[24] Kit S Lam,et al. From combinatorial chemistry to cancer-targeting peptides. , 2007, Molecular pharmaceutics.
[25] M. Weller,et al. BCL‐2‐induced glioma cell invasiveness depends on furin‐like proteases , 2004, Journal of neurochemistry.
[26] N. Seidah,et al. Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells. , 2008, The Journal of clinical investigation.
[27] B. Schäfer,et al. Identification of a rhabdomyosarcoma targeting peptide by phage display with sequence similarities to the tumour lymphatic‐homing peptide LyP‐1 , 2009, International journal of cancer.
[28] A. Klein-Szanto,et al. Elevated furin expression in aggressive human head and neck tumors and tumor cell lines , 2001, Molecular carcinogenesis.
[29] Annik Prat,et al. The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: in vivo mouse model , 2009, Molecular Cancer.
[30] R. Day,et al. Cutting back on pro-protein convertases: the latest approaches to pharmacological inhibition , 2005, Trends in Pharmacological Sciences.
[31] N. Seidah,et al. Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy. , 2002, The American journal of pathology.
[32] G. Neufeld,et al. Semaphorin-3B is an angiogenesis inhibitor that is inactivated by furin-like pro-protein convertases. , 2008, Cancer research.
[33] E. Ruoslahti,et al. C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration , 2009, Proceedings of the National Academy of Sciences.
[34] T. Clackson,et al. Phage display : a practical approach , 2004 .
[35] G. Thomas,et al. Furin at the cutting edge: From protein traffic to embryogenesis and disease , 2002, Nature Reviews Molecular Cell Biology.
[36] Erkki Ruoslahti,et al. Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels , 2003, The Journal of cell biology.
[37] Erkki Ruoslahti,et al. A tumor-homing peptide with a targeting specificity related to lymphatic vessels , 2002, Nature Medicine.
[38] N. Seidah,et al. Comparative analysis of expression of the proprotein convertases furin, PACE4, PC1 and PC2 in human lung tumours. , 1997, British Journal of Cancer.
[39] M. Komada,et al. Proteolytic processing of the hepatocyte growth factor/scatter factor receptor by furin , 1993, FEBS letters.
[40] J. Christian,et al. Site-specific Cleavage of BMP4 by Furin, PC6, and PC7* , 2009, The Journal of Biological Chemistry.
[41] C. Tsai,et al. Purification and Characterization , 2006 .
[42] A. Prat,et al. Inhibition of Proprotein Convertases Is Associated with Loss of Growth and Tumorigenicity of HT-29 Human Colon Carcinoma Cells , 2001, The Journal of Biological Chemistry.
[43] N. Seidah,et al. Proprotein convertases as therapeutic targets. , 2008, Expert opinion on therapeutic targets.
[44] W. Arap,et al. Mapping tumor vascular diversity by screening phage display libraries. , 2003, Journal of controlled release : official journal of the Controlled Release Society.
[45] Yan Li,et al. Subtractive proteomic mapping of the endothelial surface in lung and solid tumours for tissue-specific therapy , 2004, Nature.
[46] N. Seidah,et al. Processing of alpha4 integrin by the proprotein convertases: histidine at position P6 regulates cleavage. , 2003, The Biochemical journal.
[47] A. Klein-Szanto,et al. Furin inhibition results in absent or decreased invasiveness and tumorigenicity of human cancer cells , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[48] J. Enbäck,et al. Tumour-homing peptides: tools for targeting, imaging and destruction. , 2007, Biochemical Society Transactions.
[49] D. Hanahan,et al. Stage-specific vascular markers revealed by phage display in a mouse model of pancreatic islet tumorigenesis. , 2003, Cancer cell.
[50] Kit S Lam,et al. Therapeutic cancer targeting peptides. , 2002, Biopolymers.
[51] I. Fournier,et al. TACE/ADAM‐17 maturation and activation of sheddase activity require proprotein convertase activity , 2003, FEBS letters.
[52] P. Bühlmann,et al. Gene Expression Signatures Identify Rhabdomyosarcoma Subtypes and Detect a Novel t(2;2)(q35;p23) Translocation Fusing PAX3 to NCOA1 , 2004, Cancer Research.
[53] Serge Muyldermans,et al. Efficient cancer therapy with a nanobody-based conjugate. , 2004, Cancer research.
[54] K Nakayama,et al. Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins. , 1997, The Biochemical journal.
[55] N. Seidah,et al. Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides 1 Published on the World Wide Web on 17 August 1999. 1 , 1999, Brain Research.
[56] D. Scheinberg,et al. Monoclonal antibody therapy of cancer. , 1990, Cancer chemotherapy and biological response modifiers.
[57] D. Bassi,et al. Increased furin activity enhances the malignant phenotype of human head and neck cancer cells. , 2003, The American journal of pathology.