Effects of compliance mismatch on blood flow in an artery with endovascular prosthesis.

The objective of this paper is to study the mechanical effects caused by the local stiffening of an artery (due to the vascular prosthesis, for instance). At the junction of the host artery and the more rigid implantant, the abrupt change in compliance creates an abnormal stress concentration that initiates an adaptive response in the vascular tissue. The roles of both fluid and solid mechanical phenomena must be considered in the prosthesis design optimization. In this context, even the simple models could provide helpful tools for designing process. We present here a model of blood flow in compliant vessel. The artery is supposed to be an orthotropical thin elastic shell. We obtain the solution by matched asymptotic expansions. The results prove the high flexure concentration close to the compliance jump. It is shown that the use of orthotropical graft may reduce the peak value of these shear forces to a remarkable extent. Waves reflected from the suture and pressure increase in the prosthesis are discussed. Compliance mismatch is shown to reduce the peak value of maximal wall shear stress.

[1]  M. Daemen,et al.  Intimal hyperplasia in vascular grafts. , 2000, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[2]  A. Y. Cheer,et al.  Fluid Dynamics in Biology , 1993 .

[3]  H. Bauer,et al.  Dynamic Behavior of Distensible Fluid Lines Carrying a Pulsating Incompressible Liquid , 1980 .

[4]  D Liepsch,et al.  Note on wave propagation in a thin elastic tube containing a viscous fluid. , 1985, Journal of biomechanics.

[5]  C. Gans,et al.  Biomechanics: Motion, Flow, Stress, and Growth , 1990 .

[6]  V. G. Hart,et al.  Initially deformed dissimilar elastic tubes containing fluid flow , 1996 .

[7]  V. G. Hart,et al.  Joined dissimilar thin elastic tubes containing steady perfect flow , 1992 .

[8]  QuarteroniAlfio,et al.  Computational vascular fluid dynamics , 2000 .

[9]  Joel L Berry,et al.  Hemodynamics and wall mechanics of a compliance matching stent: in vitro and in vivo analysis. , 2002, Journal of vascular and interventional radiology : JVIR.

[10]  S. Timoshenko,et al.  THEORY OF PLATES AND SHELLS , 1959 .

[11]  Timothy J. Pedley,et al.  The fluid mechanics of large blood vessels , 1980 .

[12]  Erwan Donal,et al.  Experimental study of laminar blood flow through an artery treated by a stent implantation: characterisation of intra-stent wall shear stress. , 2003, Journal of biomechanics.

[13]  C Dumoulin,et al.  Mechanical behaviour modelling of balloon-expandable stents. , 2000, Journal of biomechanics.

[14]  Gianni Pedrizzetti,et al.  Flow-tissue interaction with compliance mismatch in a model stented artery. , 2004, Journal of biomechanics.

[15]  S. Greenwald,et al.  Improving vascular grafts: the importance of mechanical and haemodynamic properties , 2000, The Journal of pathology.

[16]  D. Liepsch An introduction to biofluid mechanics--basic models and applications. , 2002, Journal of biomechanics.

[17]  Alfio Quarteroni,et al.  A One Dimensional Model for Blood Flow: Application to Vascular Prosthesis , 2002 .

[18]  H. Schima,et al.  Numerical study of wall mechanics and fluid dynamics in end-to-side anastomoses and correlation to intimal hyperplasia. , 1996, Journal of biomechanics.

[19]  V. G. Hart,et al.  Joined dissimilar orthotropic elastic cylindrical membranes under internal pressure and longitudinal tension , 1993, The Journal of the Australian Mathematical Society. Series B. Applied Mathematics.

[20]  A. Leuprecht,et al.  Numerical study of hemodynamics and wall mechanics in distal end-to-side anastomoses of bypass grafts. , 2002, Journal of biomechanics.

[21]  Ivo Babuška,et al.  Mathematical Modeling and Numerical Simulation in Continuum Mechanics , 2001 .

[22]  J. Womersley Oscillatory flow in arteries: the constrained elastic tube as a model of arterial flow and pulse transmission. , 1957, Physics in medicine and biology.

[23]  M. Zamir,et al.  Effects of stent stiffness on local haemodynamics with particular reference to wave reflections. , 2004, Journal of biomechanics.

[24]  C. Hirsch,et al.  Numerical Computation of Internal and External Flows. By C. HIRSCH. Wiley. Vol. 1, Fundamentals of Numerical Discretization. 1988. 515 pp. £60. Vol. 2, Computational Methods for Inviscid and Viscous Flows. 1990, 691 pp. £65. , 1991, Journal of Fluid Mechanics.

[25]  Alfio Quarteroni,et al.  Computational vascular fluid dynamics: problems, models and methods , 2000 .