3-amino-4-sulfonylpyridinone acetamide and related pyridothiadiazine thrombin inhibitors.
暂无分享,去创建一个
Youwei Yan | S. D. Lewis | E. A. Lyle | B. J. Lucas | A. Naylor-Olsen | J. A. Krueger | F. C. Clayton | Denise J. Bickel | P. Sanderson | K. L. Savage | A. Wallace | K. J. Cutrona | D. Bohn | Denice C Welsh | S. Lewis | E. Lyle
[1] Youwei Yan,et al. Small, low nanomolar, noncovalent thrombin inhibitors lacking a group to fill the 'distal binding pocket'. , 2003, Bioorganic & medicinal chemistry letters.
[2] C. Coburn. Small-molecule direct thrombin inhibitors: 1997 - 2000 , 2001 .
[3] C. Coburn,et al. Bicyclic pyridones as potent, efficacious and orally bioavailable thrombin inhibitors. , 2000, Bioorganic & medicinal chemistry letters.
[4] R. Nutt,et al. Investigation of the S3 site of thrombin: design, synthesis and biological activity of 4-substituted 3-amino-2-pyridones incorporating P1-argininals. , 1999, Bioorganic & medicinal chemistry letters.
[5] J. Vacca,et al. Efficacious, orally bioavailable thrombin inhibitors based on 3-aminopyridinone or 3-aminopyrazinone acetamide peptidomimetic templates. , 1998, Journal of medicinal chemistry.
[6] W. M. Sanders,et al. Synthesis, evaluation, and crystallographic analysis of L-371,912: A potent and selective active-site thrombin inhibitor. , 1997 .
[7] E. Vedejs,et al. Heteroarene-2-sulfonyl Chlorides (BtsCl; ThsCl): Reagents for Nitrogen Protection and >99% Racemization-Free Phenylglycine Activation with SOCl2 , 1996 .
[8] D. Veber,et al. Inhibition of Thrombin by Peptides Containing Lysyl-α-Keto Carbonyl Derivatives , 1995, Thrombosis and Haemostasis.
[9] Y Li,et al. Crystal structure of human alpha-thrombin complexed with hirugen and p-amidinophenylpyruvate at 1.6 A resolution. , 1995, Archives of biochemistry and biophysics.
[10] J. Shafer,et al. Inhibition of thrombin and other trypsin-like serine proteinases by cyclotheonamide A. , 1993, Thrombosis research.
[11] G. Sandusky,et al. Rat model of arterial thrombosis induced by ferric chloride. , 1990, Thrombosis research.
[12] R L Smith,et al. Topically active carbonic anhydrase inhibitors. 3. Benzofuran- and indole-2-sulfonamides. , 1990, Journal of medicinal chemistry.
[13] Y. Ueno,et al. A convenient and general synthesis of alkane sulfinic acids , 1984 .
[14] J. Sprague,et al. The Syntheses of 7-Sulphamylpyrido[2,3-e]-1,2,4-Thiadiazine-1,1-Dioxide, 5,Sulphamylpyrido[4,3-e]-1,2,4-Thiadiazine-1,1-Dioxide and Certain of Their Derivatives , 1961 .