The phenotypic expansion and its boundaries

The development of sport performances in the future is a subject of myth and disagreement among experts. In particular, an article in 2004 [1] gave rise to a lively debate in the academic field. It stated that linear models can be used to predict human performance in sprint races in a far future. As arguments favoring and opposing such methodology were discussed, other publications empirically showed that the past development of performances followed a non linear trend [2, 3]. Other works, while deeply exploring the conditions leading to world records, highlighted that performance is tied to the economical and geopolitical context [4]. Here we investigated the following human boundaries : development of performances withtime in Olympic and non-Olympic events, development of sport performances with aging among humans and others species (greyhounds, thoroughbreds, mice). Development of performances from a broader point of view (demography & lifespan) in a specific sub-system centered on primary energy were also investigated. We show that all these developments are limited with time [5, 6, 7] and that previously introduced linear models are poor predictors of biological and physiological phenomena. Three major and direct determinants of sport performance are age [8, 9], technology [10, 11] and climatic conditions (temperature) [12]. However, all observed developments are related to the international context including the efficient use of primary energies. This last parameter is a major indirect propeller of performance development. We show that when physiological and societal performance indicators such as lifespan and population density depend on primary energies, the energy source, competition and mobility are key parameters for achieving longterm sustainable trajectories. Otherwise, the vast majority (98.7%) of the studied trajectories reaches 0 before 15 generations, due to the consumption of fossil energy and a low mobility rate. This led us to consider that in the present turbulent economical context and given the upcoming energy crisis, societal and physical performances are not expected to grow continuously.

[1]  J. Randers,et al.  Tracking the ecological overshoot of the human economy , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[2]  Per Bak,et al.  How Nature Works , 1996 .

[3]  G. Schwarz Estimating the Dimension of a Model , 1978 .

[4]  D. Sornette,et al.  Finite-time singularity in the dynamics of the world population, economic and financial indices , 2000, cond-mat/0002075.

[5]  E. Kasimati Economic aspects and the Summer Olympics: a review of related research. , 2003 .

[6]  Paul G Shekelle,et al.  Consequences of health trends and medical innovation for the future elderly. , 2005, Health affairs.

[7]  R. Hackert,et al.  Proximate determinants of bite force capacity in the mouse lemur , 2013 .

[8]  B. Gilland World population and food supply: can food production keep pace with population growth in the next half-century? , 2002 .

[9]  R. Cowling,et al.  The road to sustainability must bridge three great divides , 2010, Annals of the New York Academy of Sciences.

[10]  Hala Nassif,et al.  Success and decline: top 10 tennis players follow a biphasic course. , 2011, Medicine and science in sports and exercise.

[11]  A. Bejan,et al.  THE EVOLUTION OF SPEED IN ATHLETICS: WHY THE FASTEST RUNNERS ARE BLACK AND SWIMMERS WHITE , 2010 .

[12]  M. Hood Running against the wind [sports prosthetics] , 2005, IEEE Spectrum.

[13]  K. S. Seiler,et al.  Training and performance characteristics among Norwegian International Rowers 1970–2001 , 2004, Scandinavian journal of medicine & science in sports.

[14]  J. Delong,et al.  Industrial energy use and the human life history , 2011, Scientific reports.

[15]  G. Turner A comparison of The Limits to Growth with 30 years of reality , 2008 .

[16]  M. Bonsignore,et al.  Environmental conditions, air pollutants, and airway cells in runners: A longitudinal field study , 2009, Journal of sports sciences.

[17]  Leon Bennun,et al.  Horizon scan of global conservation issues for 2011. , 2011, Trends in ecology & evolution.

[18]  H. Larsen Kenyan dominance in distance running. , 2003, Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.

[19]  W. Roberts Determining a "do not start" temperature for a marathon on the basis of adverse outcomes. , 2010, Medicine and science in sports and exercise.

[20]  D. Macdonald,et al.  Scale‐free dynamics in the movement patterns of jackals , 2002 .

[21]  A. Moffat History of doping in sport , 2006 .

[22]  G. Donaldson Cold exposure and winter mortality from ischaemic heart disease, cerebrovascular disease, respiratory disease, and all causes in warm and cold regions of Europe , 1997, The Lancet.

[23]  C. Spengler,et al.  Endogenous circadian rhythm of pulmonary function in healthy humans. , 2000, American journal of respiratory and critical care medicine.

[24]  E. Ising Beitrag zur Theorie des Ferromagnetismus , 1925 .

[25]  I. Alexander,et al.  Potential use of gene transfer in athletic performance enhancement. , 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

[26]  E. Nieschlag,et al.  Reproductive functions of the ageing male. , 2004, Human reproduction update.

[27]  M. Ely,et al.  Marathon Performance in Thermally Stressing Conditions , 2007, Sports medicine.

[28]  Modelling sustainable development as a problem in earth science , 1998 .

[29]  H. D. Cooper,et al.  Scenarios for Global Biodiversity in the 21st Century , 2010, Science.

[30]  N. Orr,et al.  A Genome Scan for Positive Selection in Thoroughbred Horses , 2009, PloS one.

[31]  Deborah M. Gordon,et al.  Dynamics of task switching in harvester ants , 1989, Animal Behaviour.

[32]  J. Mackenbach Convergence and divergence of life expectancy in Europe: a centennial view , 2013, European Journal of Epidemiology.

[33]  A. D. Grey Escape Velocity: Why the Prospect of Extreme Human Life Extension Matters Now , 2004 .

[34]  Alan M. Wilson,et al.  Modern Riding Style Improves Horse Racing Times , 2009, Science.

[35]  Mark Z. Jacobson,et al.  Providing all global energy with wind, water, and solar power, Part I: Technologies, energy resources, quantities and areas of infrastructure, and materials , 2011 .

[36]  D. Falconer,et al.  Introduction to Quantitative Genetics. , 1962 .

[37]  J. Lovelock The Revenge of Gaia: Why the Earth Is Fighting Back - and How We Can Still Save Humanity , 2006 .

[38]  Jan R. Magnus,et al.  Records in Athletics Through Extreme-Value Theory , 2006 .

[39]  DAVID J. Smith A Framework for Understanding the Training Process Leading to Elite Performance , 2003, Sports medicine.

[40]  M. Kalinski State-Sponsored Research on Creatine Supplements and Blood Doping in Elite Soviet Sport , 2003, Perspectives in biology and medicine.

[41]  H. Bozdogan Model selection and Akaike's Information Criterion (AIC): The general theory and its analytical extensions , 1987 .

[42]  Michael F. Zupan,et al.  Applied Physiology of Cross-Country Skiing , 1989, Sports medicine.

[43]  M. Nimmo Exercise in the cold , 2004, Journal of sports sciences.

[44]  F. J. Richards A Flexible Growth Function for Empirical Use , 1959 .

[45]  D. Couvet,et al.  Expected impact of agriculture expansion on the world avifauna. , 2007, Comptes rendus biologies.

[46]  V. Kannisto Mode and Dispersion of the Length of Life , 2001 .

[47]  J. Vaupel,et al.  It's Never Too Late , 2003, Science.

[48]  W. Sanderson,et al.  The end of world population growth , 2001, Nature.

[49]  J G Buckley Biomechanical adaptations of transtibial amputee sprinting in athletes using dedicated prostheses. , 2000, Clinical biomechanics.

[50]  L. Hayflick Biological Aging Is No Longer an Unsolved Problem , 2007, Annals of the New York Academy of Sciences.

[51]  Matthew R. Ely,et al.  Impact of weather on marathon-running performance. , 2007, Medicine and science in sports and exercise.

[52]  Richard Kirkham,et al.  Modelling total energy costs of sport centres , 1999 .

[53]  J. M. Harris,et al.  Consumer Demand for Convenience Foods: Demographics and Expenditures , 2007 .

[54]  M. Borowitzka Limits to Growth , 1998 .

[55]  S. Wolfram Statistical mechanics of cellular automata , 1983 .

[56]  P. A. Mason,et al.  Exercise in the heat is limited by a critical internal temperature. , 2000, Journal of applied physiology.

[57]  J. Vaupel,et al.  Broken Limits to Life Expectancy , 2002, Science.

[58]  Robert W. Fogel,et al.  The Escape from Hunger and Premature Death, 1700-2100: Europe, America, and the Third World , 1989 .

[59]  S. Díaz,et al.  Biodiversity Loss Threatens Human Well-Being , 2006, PLoS biology.

[60]  J. Vaupel Biodemography of human ageing , 2010, Nature.

[61]  J. Gouyet Physics and Fractal Structures , 1996 .

[62]  Ingo Kowarik,et al.  Novel urban ecosystems, biodiversity, and conservation. , 2011, Environmental pollution.

[63]  R. Schulz,et al.  Peak performance and age among superathletes: track and field, swimming, baseball, tennis, and golf. , 1988, Journal of gerontology.

[64]  Olivier Hermine,et al.  Athlete Atypicity on the Edge of Human Achievement: Performances Stagnate after the Last Peak, in 1988 , 2010, PloS one.

[65]  Olivier Hermine,et al.  Tour de France, Giro, Vuelta, and classic European races show a unique progression of road cycling speed in the last 20 years , 2010, Journal of sports sciences.

[66]  Takemi Sugiyama,et al.  Validity and reliability of measures of television viewing time and other non‐occupational sedentary behaviour of adults: a review , 2009, Obesity reviews : an official journal of the International Association for the Study of Obesity.

[67]  T. Reilly,et al.  Circadian Variation in Sports Performance , 1996, Sports medicine.

[68]  Robert Haslinger,et al.  Quantifying self-organization with optimal predictors. , 2004, Physical review letters.

[69]  P. Whincup,et al.  Prospective study of seasonal patterns in hemostatic factors in older men and their relation to excess winter coronary heart disease deaths , 2012, Journal of thrombosis and haemostasis : JTH.

[70]  Keith Davids,et al.  Genes, Environment and Sport Performance , 2007, Sports medicine.

[71]  Jose Alvarez-Ramirez,et al.  Time-correlations in marathon arrival sequences , 2007 .

[72]  D. Gordon The organization of work in social insect colonies , 1996, Nature.

[73]  Injong Rhee,et al.  On the levy-walk nature of human mobility , 2011, TNET.

[74]  P. Medawar UNSOLVED problem of biology. , 1953, The Medical journal of Australia.

[75]  Craig Packer,et al.  Predatory senescence in ageing wolves. , 2009, Ecology letters.

[76]  W. Weaver Science and complexity. , 1948, American scientist.

[77]  Kenneth W. Wachter,et al.  Between Zeus and the Salmon , 1997 .

[78]  S. Escolano,et al.  Women and Men in Sport Performance: The Gender Gap has not Evolved since 1983. , 2010, Journal of sports science & medicine.

[79]  Mateu Sbert,et al.  Viewpoint Selection using Viewpoint Entropy , 2001, VMV.

[80]  R. Scott,et al.  Mitochondrial haplogroups associated with elite Kenyan athlete status. , 2009, Medicine and science in sports and exercise.

[81]  Albert-László Barabási,et al.  Understanding individual human mobility patterns , 2008, Nature.

[82]  D. Hazlerigg,et al.  Photorefractoriness in mammals: dissociating a seasonal timer from the circadian-based photoperiod response. , 2005, Endocrinology.

[83]  Matthew R. Ely,et al.  Neither cloud cover nor low solar loads are associated with fast marathon performance. , 2007, Medicine and science in sports and exercise.

[84]  F. Broekmans,et al.  Relationship of serum antimüllerian hormone concentration to age at menopause. , 2008, The Journal of clinical endocrinology and metabolism.

[85]  W. Schänzer,et al.  Iron status in elite young athletes: gender-dependent influences of diet and exercise , 2011, European Journal of Applied Physiology.

[86]  Andrew Balmford,et al.  Farming and the Fate of Wild Nature , 2005, Science.

[87]  N. Charness,et al.  A multilevel model analysis of expertise in chess across the life span. , 2007, Psychology and aging.

[88]  N Maffulli,et al.  Air pollution and sports performance in Beijing. , 2008, International journal of sports medicine.

[89]  S. Wolfram,et al.  Two-dimensional cellular automata , 1985 .

[90]  D. Grigg Ester Boserup's theory of agrarian change , 1979, Progress in human geography.

[91]  D. MacArthur,et al.  Loss of ACTN3 gene function alters mouse muscle metabolism and shows evidence of positive selection in humans , 2007, Nature Genetics.

[92]  Olivier Hermine,et al.  The Citius End: World Records Progression Announces the Completion of a Brief Ultra-Physiological Quest , 2008, PloS one.

[93]  R. Fogel Technophysio evolution and the measurement of economic growth , 2004 .

[94]  Donald O. Walter,et al.  Self-Organizing Systems , 1987, Life Science Monographs.

[95]  D. Marquardt An Algorithm for Least-Squares Estimation of Nonlinear Parameters , 1963 .

[96]  Leonard Hayflick,et al.  Entropy Explains Aging, Genetic Determinism Explains Longevity, and Undefined Terminology Explains Misunderstanding Both , 2007, PLoS genetics.

[97]  G. West,et al.  The importance of quantitative systemic thinking in medicine , 2012, The Lancet.

[98]  Benoit B. Mandelbrot,et al.  Fractal Geometry of Nature , 1984 .

[99]  Cooper Jd,et al.  Record performances at the Boston Marathon: biometeorological factors. , 1989 .

[100]  Till Roenneberg,et al.  Human Responses to the Geophysical Daily, Annual and Lunar Cycles , 2008, Current Biology.

[101]  T Olds,et al.  Morphological Evolution of Athletes Over the 20th Century , 2001, Sports medicine.

[102]  E. Ostrom Collective action and the evolution of social norms , 2000, Journal of Economic Perspectives.

[103]  David Cebon,et al.  Materials Selection in Mechanical Design , 1992 .

[104]  David A. Ratkowsky,et al.  Handbook of nonlinear regression models , 1990 .

[105]  C. Aegerter,et al.  Nonlinear Dynamics and Fractal Avalanches in a Pile of Rice , 2006 .

[106]  T. Geisel,et al.  The scaling laws of human travel , 2006, Nature.

[107]  K. Gaston Global patterns in biodiversity , 2000, Nature.

[108]  F. Chapin,et al.  A safe operating space for humanity , 2009, Nature.

[109]  P. Bak,et al.  Self-organized criticality in the 'Game of Life" , 1989, Nature.

[110]  Mark W Denny,et al.  Limits to running speed in dogs, horses and humans , 2008, Journal of Experimental Biology.

[111]  D. Meadows,et al.  The Limits to Growth , 1972 .

[112]  D. Pimentel,et al.  Food Production and the Energy Crisis , 1973, Science.

[113]  A F Bennett,et al.  Temperature and muscle. , 1985, The Journal of experimental biology.

[114]  W. Zipperer,et al.  Urban ecological systems: linking terrestrial ecological, physical, and socioeconomic components of metropolitan areas , 2001 .

[115]  A. D. Grey The Natural Biogerontology Portfolio , 2007 .

[116]  J. Husak,et al.  FIELD USE OF MAXIMAL SPRINT SPEED BY COLLARED LIZARDS (CROTAPHYTUS COLLARIS): COMPENSATION AND SEXUAL SELECTION , 2006, Evolution; international journal of organic evolution.

[117]  M. Bobbert,et al.  Physiological responses that account for the increased power output in speed skating using klapskates , 2000, European Journal of Applied Physiology.

[118]  H. Haberl,et al.  Quantifying and mapping the human appropriation of net primary production in earth's terrestrial ecosystems , 2007, Proceedings of the National Academy of Sciences.

[119]  V. Wright,et al.  Age-Related Rates of Decline in Performance among Elite Senior Athletes , 2008, The American journal of sports medicine.

[120]  George C. Williams,et al.  PLEIOTROPY, NATURAL SELECTION, AND THE EVOLUTION OF SENESCENCE , 1957, Science of Aging Knowledge Environment.

[121]  J. Farley,et al.  Ecological Economics : Principles and Applications , 2016 .

[122]  M. Schreckenberg Modeling Complex Systems , 2004 .

[123]  Deborah M. Gordon,et al.  Ants at Work - How an Insect Society Is Organized , 1999 .

[124]  S. Olshansky,et al.  Biological evidence for limits to the duration of life , 2004, Biogerontology.

[125]  P. Verhulst Recherches mathématiques sur la loi d’accroissement de la population , 2022, Nouveaux mémoires de l'Académie royale des sciences et belles-lettres de Bruxelles.

[126]  C. Holling Simplifying the complex: The paradigms of ecological function and structure , 1987 .

[127]  Dc Blest Lower bounds for athletic performance , 1996 .

[128]  D. Pauly,et al.  Length-based methods in fisheries research , 1987 .

[129]  T. Sharot The optimism bias , 2011, Current Biology.

[130]  D. Meadows,et al.  Beyond the Limits , 1992 .

[131]  Neo D. Martinez,et al.  Approaching a state shift in Earth’s biosphere , 2012, Nature.

[132]  K. Laaidi,et al.  Temperature-related mortality in France, a comparison between regions with different climates from the perspective of global warming , 2006, International journal of biometeorology.

[133]  N. Orr,et al.  A Sequence Polymorphism in MSTN Predicts Sprinting Ability and Racing Stamina in Thoroughbred Horses , 2010, PloS one.

[134]  Michael J Joyner,et al.  Endurance exercise performance: the physiology of champions , 2008, The Journal of physiology.

[135]  P. Ehrlich The Population Bomb. , 1962, Canadian Medical Association journal.

[136]  Melanie E. Moses,et al.  Allometry of human fertility and energy use , 2003 .

[137]  R. Hilborn,et al.  Predation by Bears Drives Senescence in Natural Populations of Salmon , 2007, PloS one.

[138]  A. Deslauriers,et al.  Application of the Gompertz equation for the study of xylem cell development , 2003 .

[139]  Sarah L. Hamilton,et al.  UK adults exhibit higher step counts in summer compared to winter months , 2008, Annals of human biology.

[140]  Mark Hargreaves,et al.  Physiological limits to exercise performance in the heat. , 2008, Journal of science and medicine in sport.

[141]  S. Jay Olshansky,et al.  Prospects for Human Longevity , 2001, Science.

[142]  Bharat Bhushan,et al.  Biomimetics: lessons from nature–an overview , 2009, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences.

[143]  M. Hoffmann,et al.  The changing fates of the world's mammals , 2011, Philosophical Transactions of the Royal Society B: Biological Sciences.

[144]  Mark Harvey,et al.  The new competition for land: Food, energy, and climate change , 2011 .

[145]  A. Crétual,et al.  Inverse relationship between percentage body weight change and finishing time in 643 forty-two-kilometre marathon runners , 2010, British Journal of Sports Medicine.

[146]  R. Scott,et al.  Demographic characteristics of elite Kenyan endurance runners , 2006, Journal of sports sciences.

[147]  J. Losos,et al.  Do Lizards Avoid Habitats in Which Performance Is Submaximal? The Relationship between Sprinting Capabilities and Structural Habitat Use in Caribbean Anoles , 1999, The American Naturalist.

[148]  J. Capmany,et al.  A new model of bandwidth growth estimation based on the gompertz curve: application to optical access networks , 2004, Journal of Lightwave Technology.

[149]  Alejandro Lucia,et al.  Physiology of Professional Road Cycling , 2001, Sports medicine.

[150]  Pat Monaghan,et al.  Telomere length in early life predicts lifespan , 2012, Proceedings of the National Academy of Sciences.

[151]  S Folkard,et al.  Complex interaction of the sleep-wake cycle and circadian phase modulates mood in healthy subjects. , 1997, Archives of general psychiatry.

[152]  W. Hamilton The moulding of senescence by natural selection. , 1966, Journal of theoretical biology.

[153]  James Gleick Chaos: Making a New Science , 1987 .

[154]  D. Leyk,et al.  Performance, training and lifestyle parameters of marathon runners aged 20-80 years: results of the PACE-study. , 2009, International journal of sports medicine.

[155]  H. Rusko Development of aerobic power in relation to age and training in cross-country skiers. , 1992, Medicine and science in sports and exercise.

[156]  Guy Theraulaz,et al.  Self-Organization in Biological Systems , 2001, Princeton studies in complexity.

[157]  Teng Huang Teaching unawareness: the curriculum of desire and love in the risk society , 2010 .

[158]  R. Eccles,et al.  An Explanation for the Seasonality of Acute Upper Respiratory Tract Viral Infections , 2002, Acta oto-laryngologica.

[159]  Hala Nassif,et al.  Success in Developing Regions: World Records Evolution through a Geopolitical Prism , 2009, PloS one.

[160]  K. Balakrishnan,et al.  Energy and human health. , 2013, Annual review of public health.

[161]  R. Maughan,et al.  Effects of ambient temperature on the capacity to perform prolonged cycle exercise in man. , 1997, Medicine and science in sports and exercise.

[162]  Dora Marinova,et al.  Modelling sustainability , 2011, Math. Comput. Simul..

[163]  P. Kirk Visscher,et al.  Lifetime learning by foraging honey bees , 1994, Animal Behaviour.

[164]  F. Kessler Projections , 2020, International Encyclopedia of Human Geography.

[165]  Matthew Kam,et al.  The Case for Technology in Developing Regions , 2005, Computer.

[166]  G. Weisbuch Sustainable Development and Spatial Inhomogeneities , 2012, Journal of Statistical Physics.

[167]  J. Wilmoth Demography of longevity: past, present, and future trends , 2000, Experimental Gerontology.

[168]  P. Delamarche,et al.  Athletic performance and weight changes during the "Marathon of Sands" in athletes well-trained in endurance. , 2009, International journal of sports medicine.

[169]  Yannis P Pitsiladis,et al.  Drinking Behaviors of Elite Male Runners During Marathon Competition , 2012, Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine.

[170]  G. Williams Chaos theory tamed , 1997 .

[171]  D. Helbing,et al.  Energy laws in human travel behaviour , 2003, cond-mat/0301386.

[172]  R. Howard Objective evidence of rising population ability: a detailed examination of longitudinal chess data , 2005 .

[173]  Jeremy Woods,et al.  Energy and the food system , 2010, Philosophical Transactions of the Royal Society B: Biological Sciences.

[174]  H. Dolles,et al.  Addressing ecology and sustainability in mega-sporting events: The 2006 football World Cup in Germany , 2010, Journal of Management & Organization.

[175]  W. Franke,et al.  Hormonal doping and androgenization of athletes: a secret program of the German Democratic Republic government. , 1997, Clinical chemistry.

[176]  Philippe Hellard,et al.  Exponential growth combined with exponential decline explains lifetime performance evolution in individual and human species , 2011, AGE.

[177]  E. Krenning,et al.  Peak bone mineral density, lean body mass and fractures. , 2010, Bone.

[178]  J. Folland,et al.  Similarity of polygenic profiles limits the potential for elite human physical performance , 2008, The Journal of physiology.

[179]  Jose Alvarez-Ramirez,et al.  Scaling properties of marathon races , 2006 .

[180]  B. Kayser,et al.  Current anti-doping policy: a critical appraisal , 2007, BMC medical ethics.

[181]  D. Phillips,et al.  Exposure to New York City as a risk factor for heart attack mortality. , 1999, Psychosomatic medicine.

[182]  R. M. Alexander Models and the scaling of energy costs for locomotion , 2005, Journal of Experimental Biology.

[183]  P. Werner,et al.  Urban Patterns and Biological Diversity: A Review , 2010 .

[184]  Geoffroy Berthelot,et al.  Impact of Environmental Parameters on Marathon Running Performance , 2012, PloS one.

[185]  B. Mandelbrot How Long Is the Coast of Britain? Statistical Self-Similarity and Fractional Dimension , 1967, Science.

[186]  Turid Rustad,et al.  Superchilling of food: A review , 2011 .

[187]  G. Atkinson,et al.  Seasonal rhythms and exercise. , 2005, Clinics in sports medicine.

[188]  Health And Longevity , 1934 .

[189]  M. Antrop Landscape change and the urbanization process in Europe , 2004 .

[190]  Des Spence,et al.  A sporting chance , 2006, BMJ : British Medical Journal.

[191]  José González-Alonso,et al.  Hyperthermia Impairs Brain, Heart and Muscle Function in Exercising Humans , 2007, Sports medicine.

[192]  Roger Bartlett,et al.  Introduction to sports biomechanics , 2007 .

[193]  J. Baron,et al.  Mechanisms limiting body growth in mammals. , 2011, Endocrine reviews.

[194]  J. Delong,et al.  Current Demographics Suggest Future Energy Supplies Will Be Inadequate to Slow Human Population Growth , 2010, PloS one.

[195]  D. Wells,et al.  Gene doping: the hype and the reality , 2008, British journal of pharmacology.

[196]  D. Irschick,et al.  How does selection operate on whole-organism functional performance capacities? A review and synthesis , 2008 .

[197]  Spiro N. Pollalis,et al.  Estimation model and benchmarks for heating energy consumption of schools and sport facilities in Germany , 2012 .

[198]  Christopher Freeman,et al.  Models of doom : a critique of The limits to growth , 1976 .

[199]  Donald A. Berry,et al.  The science of doping , 2008, Nature.

[200]  Hirofumi Tanaka,et al.  Declines in physiological functional capacity with age: a longitudinal study in peak swimming performance. , 2003, Journal of applied physiology.

[201]  James W. Vaupel,et al.  Reductions in mortality at advanced ages: several decades of evidence from 27 countries. , 1994 .

[202]  Andy P. Field,et al.  Discovering Statistics Using SPSS , 2000 .

[203]  Andrew J. Hansen,et al.  EFFECTS OF EXURBAN DEVELOPMENT ON BIODIVERSITY: PATTERNS, MECHANISMS, AND RESEARCH NEEDS , 2005 .

[204]  Rhodri Thomas,et al.  Modelling the economic impact of sports events: the case of the Beijing Olympics , 2013 .

[205]  I. Macdonald,et al.  Physiological responses to a cold, wet, and windy environment during prolonged intermittent walking. , 1997, The American journal of physiology.

[206]  M. Sambridge,et al.  Monte Carlo analysis of inverse problems , 2002 .

[207]  Frank E. Marino,et al.  Advantages of smaller body mass during distance running in warm, humid environments , 2000, Pflügers Archiv.

[208]  J. Healy,et al.  Excess winter mortality in Europe: a cross country analysis identifying key risk factors , 2003, Journal of epidemiology and community health.

[209]  Richard Heinberg,et al.  The End of Growth: Adapting to Our New Economic Reality , 2011 .

[210]  Miller,et al.  Concept of radius of gyration in general relativity. , 1993, Physical review. D, Particles and fields.

[211]  Giovanni Coco,et al.  Forecasting the limits of resilience: integrating empirical research with theory , 2009, Proceedings of the Royal Society B: Biological Sciences.

[212]  O. L. Gilbert,et al.  The Ecology of Urban Habitats , 1989, Springer Netherlands.

[213]  T. Garland,et al.  THE EVOLUTION OF AGING AND AGE‐RELATED PHYSICAL DECLINE IN MIC SELECTIVELY BRED FOR HIGH VOLUNTARY EXERCISE , 2006, Evolution; international journal of organic evolution.

[214]  Robin Thompson,et al.  ASREML user guide release 1.0 , 2002 .

[215]  E. Coyle Physiological Regulation of Marathon Performance , 2007, Sports medicine.

[216]  J. Diamond Collapse : how societies choose to fail or survive , 2005 .

[217]  Leonard Hayflick,et al.  The future of ageing , 2000, Nature.

[218]  A. H. Boussabaine A comparative approach for modelling the cost of energy in sport facilities , 2001 .

[219]  Michelle Rucker,et al.  Encyclopedia of Life , 2014 .

[220]  C. Bellamy The State of the World's Children 2003 , 2003 .

[221]  D. Miles The race goes to the swift: fitness consequences of variation in sprint performance in juvenile lizards , 2004 .

[222]  J. Husak Does survival depend on how fast you can run or how fast you do run , 2006 .

[223]  Roger White,et al.  An Activity-Based Cellular Automaton Model to Simulate Land-Use Dynamics , 2012 .

[224]  S. Escolano,et al.  Technology & swimming: 3 steps beyond physiology , 2010 .

[225]  G. Boeuf,et al.  The Timing of the Shrew: Continuous Melatonin Treatment Maintains Youthful Rhythmic Activity in Aging Crocidura russula , 2009, PloS one.

[226]  Mark Z. Jacobson,et al.  Providing all global energy with wind, water, and solar power, Part II: Reliability, system and transmission costs, and policies , 2011 .

[227]  David R. Pendergast,et al.  Application of theoretical principles to swimsuit drag reduction , 2006 .