Significance of Statistical Analysis to the Acceptance of a Clinical Research Report - Actual Submitted Treatises and Responses from Reviewers

We reported the effect of prophylactic pentazocine administration on opioid-induced pruritus after cesarean section under spinal anesthesia using opioids（Anesth Analg 124； 1930-1934：2017）. There were additional requests from the reviewer（Statistical Editor）when the paper was submitted initially. In particular, the reviewer required statistical methods based on the characteristics of data and com mented on the method of their notation. We present the kind of statistical analysis that was pointed out in the process from first submission to publication of our paper using the actual submitted paper.