Mechanisms of medial arterial calcification in diabetes.
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A. Orekhov | D. Chistiakov | Y. Bobryshev | I. Sobenin | Dimitry A Chistiakov | Igor A Sobenin | Alexander N Orekhov | Yuri V Bobryshev
[1] M. Emoto,et al. Effects of Pravastatin on Serum Osteoprotegerin Levels in Patients With Hypercholesterolemia and Type 2 Diabetes , 2010, Angiology.
[2] David M Maahs,et al. Low Plasma Adiponectin Levels Predict Progression of Coronary Artery Calcification , 2005, Circulation.
[3] Lei Zhao,et al. Angiotensin-(1-7) inhibits vascular calcification in rats , 2013, Peptides.
[4] K. Matthews,et al. Coronary and aortic calcification among women 8 years after menopause and their premenopausal risk factors : the healthy women study. , 1999, Arteriosclerosis, thrombosis, and vascular biology.
[5] P. Price,et al. Bisphosphonates Alendronate and Ibandronate Inhibit Artery Calcification at Doses Comparable to Those That Inhibit Bone Resorption , 2001, Arteriosclerosis, thrombosis, and vascular biology.
[6] H. Ryoo,et al. Tumor necrosis factor-alpha increases alkaline phosphatase expression in vascular smooth muscle cells via MSX2 induction. , 2010, Biochemical and biophysical research communications.
[7] J. Atkinson,et al. Pioglitazone Improves Aortic Wall Elasticity in a Rat Model of Elastocalcinotic Arteriosclerosis , 2005, Hypertension.
[8] Mark Butlin,et al. Persistent effect of early, brief angiotensin-converting enzyme inhibition on segmental pressure dependency of aortic stiffness in spontaneously hypertensive rats , 2012, Journal of hypertension.
[9] Z. Ungvari,et al. Regulation of Bone Morphogenetic Protein-2 Expression in Endothelial Cells , 2005 .
[10] B. Baxter,et al. Elastin Degradation and Calcification in an Abdominal Aorta Injury Model: Role of Matrix Metalloproteinases , 2004, Circulation.
[11] Su‐Li Cheng,et al. TNFR1-activated reactive oxidative species signals up-regulate osteogenic Msx2 programs in aortic myofibroblasts. , 2012, Endocrinology.
[12] T. Shoji,et al. Different risk factors for peripheral vascular calcification between diabetic and non-diabetic haemodialysis patients – importance of glycaemic control , 2002, Diabetologia.
[13] Y. Yokogawa,et al. Growth of calcium hydroxyapatite (Ca-HAp) on cholesterol and cholestanol crystals from a simulated body fluid: A possible insight into the pathological calcifications associated with atherosclerosis. , 2006, Journal of colloid and interface science.
[14] Paul Schoenhagen,et al. Coronary artery calcification and changes in atheroma burden in response to established medical therapies. , 2007, Journal of the American College of Cardiology.
[15] G. Werstuck,et al. Leptin promotes osteoblast differentiation and mineralization of primary cultures of vascular smooth muscle cells by inhibiting glycogen synthase kinase (GSK)-3β. , 2012, Biochemical and biophysical research communications.
[16] J. Després,et al. Angiotensin receptor blockers are associated with a lower remodelling score of stenotic aortic valves , 2011, European journal of clinical investigation.
[17] Xianwu Li,et al. BMP-2 promotes phosphate uptake, phenotypic modulation, and calcification of human vascular smooth muscle cells. , 2008, Atherosclerosis.
[18] F. Parhami,et al. Tumor Necrosis Factor-&agr; Promotes In Vitro Calcification of Vascular Cells via the cAMP Pathway , 2000, Circulation.
[19] E. Rimm,et al. Fetuin-A , Type 2 Diabetes , and Risk of Cardiovascular Disease in Older Adults The Cardiovascular Health Study , 2012 .
[20] T. Douchi,et al. The leptin receptor in human osteoblasts and the direct effect of leptin on bone metabolism , 2004, Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.
[21] S. Yamagishi,et al. Prevention of diabetic vascular calcification by nifedipine, a dihydropyridine-based calcium channel blocker. , 2007, Medical hypotheses.
[22] E. Henriksen,et al. Role of glycogen synthase kinase-3 in insulin resistance and type 2 diabetes. , 2006, Current drug targets.
[23] J. Skepper,et al. Multifunctional roles for serum protein fetuin-a in inhibition of human vascular smooth muscle cell calcification. , 2005, Journal of the American Society of Nephrology : JASN.
[24] M. Mäyränpää,et al. Induction of local angiotensin II-producing systems in stenotic aortic valves. , 2004, Journal of the American College of Cardiology.
[25] P. Sarkar,et al. Relationship of serum osteocalcin levels with blood glucose, insulin resistance and lipid profile in central Indian men with type 2 diabetes , 2012, Archives of physiology and biochemistry.
[26] Jack L. Martin,et al. Diabetes-Induced Oxidative Stress and Low-Grade Inflammation in Porcine Coronary Arteries , 2003, Circulation.
[27] R. Terkeltaub,et al. Concerted regulation of inorganic pyrophosphate and osteopontin by akp2, enpp1, and ank: an integrated model of the pathogenesis of mineralization disorders. , 2004, The American journal of pathology.
[28] M. Reilly,et al. Adipokines, insulin resistance, and coronary artery calcification. , 2008, Journal of the American College of Cardiology.
[29] S. Vukicevic,et al. Ten-year experience with sevelamer and calcium salts as phosphate binders. , 2010, Clinical journal of the American Society of Nephrology : CJASN.
[30] D. Dichek,et al. Smooth Muscle Cells Give Rise to Osteochondrogenic Precursors and Chondrocytes in Calcifying Arteries , 2009, Circulation research.
[31] W. Richtering,et al. Hierarchical Role of Fetuin-A and Acidic Serum Proteins in the Formation and Stabilization of Calcium Phosphate Particles* , 2008, Journal of Biological Chemistry.
[32] Hui Chen,et al. The effects of diabetes mellitus and diabetic nephropathy on bone and mineral metabolism in T2DM patients. , 2013, Diabetes research and clinical practice.
[33] Veena V. Naik,et al. Diabetes mellitus accelerates cartilaginous metaplasia and calcification in atherosclerotic vessels of LDLr mutant mice. , 2013, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.
[34] Simon R. Goodyear,et al. PHOSPHO1 is essential for mechanically competent mineralization and the avoidance of spontaneous fractures. , 2010, Bone.
[35] Dean P. Jones. Redefining oxidative stress. , 2006, Antioxidants & redox signaling.
[36] P. Low,et al. Imaging of Atherosclerosis in Apoliprotein E Knockout Mice: Targeting of a Folate-Conjugated Radiopharmaceutical to Activated Macrophages , 2010, Journal of Nuclear Medicine.
[37] J. Kappes,et al. Oxidative Stress Induces Vascular Calcification through Modulation of the Osteogenic Transcription Factor Runx2 by AKT Signaling* , 2008, Journal of Biological Chemistry.
[38] Yong Sun,et al. Smooth Muscle Cell–Specific Runx2 Deficiency Inhibits Vascular Calcification , 2012, Circulation research.
[39] J. Millán,et al. Novel Inhibitors of Alkaline Phosphatase Suppress Vascular Smooth Muscle Cell Calcification , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[40] C. Kramer,et al. The association of lesion eccentricity with plaque morphology and components in the superficial femoral artery: a high-spatial-resolution, multi-contrast weighted CMR study , 2010, Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance.
[41] N. Bruining,et al. Coronary calcium significantly affects quantitative analysis of coronary ultrasound: importance for atherosclerosis progression/regression studies , 2009, Coronary artery disease.
[42] G. Nicholson,et al. Leptin Inhibits Osteoclast Generation , 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[43] P. Vuong,et al. Arterial calcifications: morphological aspects and their pathological implications , 2001, Zeitschrift für Kardiologie.
[44] Z. Massy,et al. The pathophysiology of vascular calcification: are osteoclast-like cells the missing link? , 2008, Diabetes & metabolism.
[45] A. Angelini,et al. Widespread Increase in Myeloid Calcifying Cells Contributes to Ectopic Vascular Calcification in Type 2 Diabetes , 2011, Circulation research.
[46] K. Corsi,et al. Differential Effect of BMP4 on NIH/3T3 and C2C12 Cells: Implications for Endochondral Bone Formation , 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[47] L. Gormsen,et al. Simvastatin Reduces Plasma Osteoprotegerin in Type 2 Diabetic Patients With Microalbuminuria , 2007 .
[48] K. Watson,et al. Multilineage Potential of Cells From the Artery Wall , 2003, Circulation.
[49] S. Hazen,et al. A CD36‐dependent signaling cascade is necessary for macrophage foam cell formation , 2006, Cell metabolism.
[50] E. Mannarino,et al. Association between circulating osteoprogenitor cell numbers and bone mineral density in postmenopausal osteoporosis , 2010, Osteoporosis International.
[51] A. Goustin,et al. The "thrifty" gene encoding Ahsg/Fetuin-A meets the insulin receptor: Insights into the mechanism of insulin resistance. , 2011, Cellular signalling.
[52] N. Liu,et al. A rat model of diabetic artery calcification , 2012, Journal of Endocrinological Investigation.
[53] M Suhonen,et al. Medial artery calcification. A neglected harbinger of cardiovascular complications in non-insulin-dependent diabetes mellitus. , 1996, Arteriosclerosis, thrombosis, and vascular biology.
[54] R. Adler,et al. Diabetes Mellitus and Osteoporosis , 2013, Current Diabetes Reports.
[55] Su‐Li Cheng,et al. Msx2 Promotes Osteogenesis and Suppresses Adipogenic Differentiation of Multipotent Mesenchymal Progenitors* , 2003, Journal of Biological Chemistry.
[56] M. Reilly,et al. Lipoprotein(a) is strongly associated with coronary artery calcification in type-2 diabetic women. , 2011, International journal of cardiology.
[57] J. Ix,et al. The association of fetuin-A with cardiovascular disease mortality in older community-dwelling adults: the Rancho Bernardo study. , 2012, Journal of the American College of Cardiology.
[58] M. Jensen,et al. Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes. , 1999, Endocrinology.
[59] M. Nielsen,et al. Abdominal aortic calcification quantified by the Morphological Atherosclerotic Calcification Distribution (MACD) index is associated with features of the metabolic syndrome , 2011, BMC cardiovascular disorders.
[60] C. Behre. Adiponectin, obesity and atherosclerosis , 2007, Scandinavian journal of clinical and laboratory investigation.
[61] A. Avogaro,et al. Procalcific Phenotypic Drift of Circulating Progenitor Cells in Type 2 Diabetes with Coronary Artery Disease , 2012, Experimental diabetes research.
[62] B. Stec,et al. Pharmacological inhibition of PHOSPHO1 suppresses vascular smooth muscle cell calcification , 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[63] J. J. Rivera,et al. The relationship of insulin resistance and extracoronary calcification in the multi-ethnic study of atherosclerosis. , 2011, Atherosclerosis.
[64] D. Agrawal,et al. Role of matrix Gla protein in angiotensin II-induced exacerbation of vascular calcification. , 2012, American journal of physiology. Heart and circulatory physiology.
[65] M. Yokoyama,et al. Transforming Growth Factor-β Signaling Enhances Transdifferentiation of Macrophages into Smooth Muscle–Like Cells , 2006, Hypertension Research.
[66] S. Yano,et al. Serum Osteocalcin/Bone-Specific Alkaline Phosphatase Ratio Is a Predictor for the Presence of Vertebral Fractures in Men with Type 2 Diabetes , 2009, Calcified Tissue International.
[67] M. Inaba,et al. Aortic calcification in haemodialysis patients with diabetes mellitus. , 2005, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
[68] M. Hayden,et al. Calcific uremic arteriolopathy , 2010, Oxidative medicine and cellular longevity.
[69] M. Criqui,et al. Blood Pressure and Vascular Calcification , 2010, Hypertension.
[70] J. Blacher,et al. Influence of biochemical alterations on arterial stiffness in patients with end-stage renal disease. , 1998, Arteriosclerosis, thrombosis, and vascular biology.
[71] F. Parhami,et al. Oxidative stress modulates osteoblastic differentiation of vascular and bone cells. , 2001, Free radical biology & medicine.
[72] Hiroki Matsui,et al. Notch Signaling Pathway Enhances Bone Morphogenetic Protein 2 (BMP2) Responsiveness of Msx2 Gene to Induce Osteogenic Differentiation and Mineralization of Vascular Smooth Muscle Cells* , 2011, The Journal of Biological Chemistry.
[73] M. Budoff,et al. Visualizing coronary calcium is associated with improvements in adherence to statin therapy. , 2006, Atherosclerosis.
[74] Kim Km. Calcification of matrix vesicles in human aortic valve and aortic media. , 1976 .
[75] P. Chambon,et al. The nuclear hormone receptor PPARγ counteracts vascular calcification by inhibiting Wnt5a signalling in vascular smooth muscle cells , 2012, Nature Communications.
[76] M. Budoff,et al. Coronary artery calcification and mortality in diabetic patients with proteinuria. , 2010, Kidney international.
[77] R. Elashoff,et al. Coronary-artery calcification in young adults with end-stage renal disease who are undergoing dialysis. , 2000, The New England journal of medicine.
[78] H. Kuhn,et al. Upregulation of lectin-like oxidized low density lipoprotein receptor 1 (LOX-1) expression in human endothelial cells by modified high density lipoproteins. , 2012, Biochemical and biophysical research communications.
[79] L. Schurgers,et al. Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: a potential mechanism for accelerated vascular calcification in ESRD. , 2004, Journal of the American Society of Nephrology : JASN.
[80] H. Vestergaard,et al. Increased levels of the calcification marker Matrix Gla Protein and the inflammatory markers YKL-40 and CRP in patients with type 2 diabetes and ischemic heart disease , 2010, Cardiovascular diabetology.
[81] W. Jacob,et al. Apoptosis and related proteins in different stages of human atherosclerotic plaques. , 1998, Circulation.
[82] T. Latifi,et al. Diet-induced Diabetes Activates an Osteogenic Gene Regulatory Program in the Aortas of Low Density Lipoprotein Receptor-deficient Mice* , 1998, The Journal of Biological Chemistry.
[83] G. Schernthaner,et al. Fetuin-A Levels Are Increased in Patients With Type 2 Diabetes and Peripheral Arterial Disease , 2010, Diabetes Care.
[84] G. King,et al. Mechanisms of cardiovascular complications in diabetes and potential new pharmacological therapies , 2003 .
[85] S. Yamagishi,et al. Nifedipine inhibits gene expression of receptor for advanced glycation end products (RAGE) in endothelial cells by suppressing reactive oxygen species generation. , 2004, Drugs under experimental and clinical research.
[86] D. Rader,et al. Lipases as modulators of atherosclerosis in murine models. , 2007, Current drug targets.
[87] W. R. Taylor,et al. Bone Morphogenic Protein 4 Produced in Endothelial Cells by Oscillatory Shear Stress Stimulates an Inflammatory Response* , 2003, Journal of Biological Chemistry.
[88] Y. Ouchi,et al. Statins Protect Human Aortic Smooth Muscle Cells From Inorganic Phosphate-Induced Calcification by Restoring Gas6-Axl Survival Pathway , 2006, Circulation research.
[89] T. Rabelink,et al. Differentiation of Bone Marrow-Derived Endothelial Progenitor Cells Is Shifted into a Proinflammatory Phenotype by Hyperglycemia , 2009, Molecular medicine.
[90] J. Westendorf. Transcriptional co‐repressors of Runx2 , 2006, Journal of cellular biochemistry.
[91] M. McKee,et al. Phosphate regulation of vascular smooth muscle cell calcification. , 2000, Circulation research.
[92] R. Pignolo,et al. Circulating osteogenic cells: Implications for injury, repair, and regeneration , 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[93] Mingxia Xiong,et al. Role of TGF-β1 in Bone Matrix Production in Vascular Smooth Muscle Cells Induced by a High-Phosphate Environment , 2010, Nephron Experimental Nephrology.
[94] B. A. Byers,et al. Exogenous Runx2 expression enhances in vitro osteoblastic differentiation and mineralization in primary bone marrow stromal cells. , 2004, Tissue engineering.
[95] A. Caudrillier,et al. Cell-specific effects of TNF-α and IL-1β on alkaline phosphatase: implication for syndesmophyte formation and vascular calcification , 2011, Laboratory Investigation.
[96] M. Emoto,et al. Fetuin-A and the cardiovascular system. , 2012, Advances in clinical chemistry.
[97] Paul J Thornalley,et al. Increased Glycation and Oxidative Damage to Apolipoprotein B100 of LDL Cholesterol in Patients With Type 2 Diabetes and Effect of Metformin , 2010, Diabetes.
[98] C. Reutelingsperger,et al. Fetuin-A protects against atherosclerotic calcification in CKD. , 2009, Journal of the American Society of Nephrology : JASN.
[99] M. Kurabayashi,et al. Activation of receptor for advanced glycation end products induces osteogenic differentiation of vascular smooth muscle cells. , 2011, Journal of atherosclerosis and thrombosis.
[100] M. Budoff,et al. Diabetes and progression of coronary calcium under the influence of statin therapy. , 2005, American heart journal.
[101] M. Boffa,et al. Lipoprotein(a): a unique risk factor for cardiovascular disease. , 2006, Clinics in laboratory medicine.
[102] Zhejun Cai,et al. Pioglitazone attenuates progression of aortic valve calcification via down-regulating receptor for advanced glycation end products , 2012, Basic Research in Cardiology.
[103] S. Ylä-Herttuala,et al. Effects of clodronate (dichloromethylene bisphosphonate) on the development of experimental atherosclerosis in rabbits. , 1994, The Journal of laboratory and clinical medicine.
[104] Naifeng Liu,et al. Advanced glycation end-product Nε-carboxymethyl-Lysine accelerates progression of atherosclerotic calcification in diabetes. , 2012, Atherosclerosis.
[105] E. Golub. Biomineralization and matrix vesicles in biology and pathology , 2011, Seminars in Immunopathology.
[106] P. Reaven,et al. Coronary artery and abdominal aortic calcification are associated with cardiovascular disease in type 2 diabetes , 2005, Diabetologia.
[107] R. Touyz,et al. Angiotensin II and the vascular phenotype in hypertension , 2011, Expert Reviews in Molecular Medicine.
[108] M. Kurabayashi,et al. Azelnidipine inhibits Msx2-dependent osteogenic differentiation and matrix mineralization of vascular smooth muscle cells. , 2012, International heart journal.
[109] H. Izutani,et al. Recipient macrophage depletion reduces the severity of graft coronary arteriosclerosis in the rat retransplantation model. , 1997, Transplantation proceedings.
[110] Y. Ouchi,et al. Age‐related Loss of Bone Mass and Aortic/Aortic Valve Calcification–Reevaluation of Recommended Dietary Allowance of Calcium in the Elderly a , 1993, Annals of the New York Academy of Sciences.
[111] Michael D. Schneider,et al. The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice. , 2010, The Journal of clinical investigation.
[112] J. Skepper,et al. Apoptosis Regulates Human Vascular Calcification In Vitro: Evidence for Initiation of Vascular Calcification by Apoptotic Bodies , 2000, Circulation research.
[113] S. Khosla,et al. Osteocalcin expression by circulating endothelial progenitor cells in patients with coronary atherosclerosis. , 2008, Journal of the American College of Cardiology.
[114] H. Schelbert,et al. Improvement in coronary endothelial function is independently associated with a slowed progression of coronary artery calcification in type 2 diabetes mellitus. , 2009, European heart journal.
[115] G. Lamas,et al. Medical Therapy for Calcific Aortic Stenosis , 2012, Journal of cardiovascular pharmacology and therapeutics.
[116] R. Aebersold,et al. Smooth Muscle Cell Phenotypic Transition Associated With Calcification: Upregulation of Cbfa1 and Downregulation of Smooth Muscle Lineage Markers , 2001, Circulation research.
[117] R. Mecham,et al. Accelerated calcification represses the expression of elastic fiber components and lysyl oxidase in cultured bovine aortic smooth muscle cells. , 2002, Journal of atherosclerosis and thrombosis.
[118] Naifeng Liu,et al. Advanced glycation end products accelerate rat vascular calcification through RAGE/oxidative stress , 2013, BMC Cardiovascular Disorders.
[119] M. Mayr,et al. Calcium Regulates Key Components of Vascular Smooth Muscle Cell–Derived Matrix Vesicles to Enhance Mineralization , 2011, Circulation research.
[120] F. Parhami,et al. Lipid oxidation products have opposite effects on calcifying vascular cell and bone cell differentiation. A possible explanation for the paradox of arterial calcification in osteoporotic patients. , 1997, Arteriosclerosis, thrombosis, and vascular biology.
[121] Takayuki Asahara,et al. Isolation of Putative Progenitor Endothelial Cells for Angiogenesis , 1997, Science.
[122] R. Foley,et al. Serum phosphorus levels associate with coronary atherosclerosis in young adults. , 2009, Journal of the American Society of Nephrology : JASN.
[123] Z. Al-Aly,et al. Aortic Msx2-Wnt Calcification Cascade Is Regulated by TNF-&agr;–Dependent Signals in Diabetic Ldlr−/− Mice , 2007, Arteriosclerosis, thrombosis, and vascular biology.
[124] N. Chen,et al. Verapamil inhibits calcification and matrix vesicle activity of bovine vascular smooth muscle cells. , 2010, Kidney international.
[125] C. Lang,et al. Impact of renin-angiotensin system blockade therapy on outcome in aortic stenosis. , 2011, Journal of the American College of Cardiology.
[126] S. Stock,et al. Atorvastatin Inhibits Hypercholesterolemia-Induced Calcification in the Aortic Valves via the Lrp5 Receptor Pathway , 2005, Circulation.
[127] M. Reilly,et al. Usefulness of insulin resistance estimation and the metabolic syndrome in predicting coronary atherosclerosis in type 2 diabetes mellitus. , 2011, The American journal of cardiology.
[128] H. Dietz,et al. Targetting of the gene encoding fibrillin–1 recapitulates the vascular aspect of Marfan syndrome , 1997, Nature Genetics.
[129] K. Miyazono,et al. Endogenous TGF‐β signaling suppresses maturation of osteoblastic mesenchymal cells , 2004, The EMBO journal.
[130] M. Reilly,et al. Apolipoprotein B but not LDL Cholesterol Is Associated With Coronary Artery Calcification in Type 2 Diabetic Whites , 2009, Diabetes.
[131] S. Tyagi,et al. Vasa vasorum in plaque angiogenesis, metabolic syndrome, type 2 diabetes mellitus, and atheroscleropathy: a malignant transformation , 2004, Cardiovascular Diabetology.
[132] A. Orekhov,et al. Vascular Extracellular Matrix in Atherosclerosis , 2013, Cardiology in review.
[133] A. Mukherjee,et al. Tumor Necrosis Factor-α (TNF) Stimulates RANKL-induced Osteoclastogenesis via Coupling of TNF Type 1 Receptor and RANK Signaling Pathways* , 2001, The Journal of Biological Chemistry.
[134] S. Mudaliar,et al. Potential role of glycogen synthase kinase-3 in skeletal muscle insulin resistance of type 2 diabetes. , 2000, Diabetes.
[135] S. Klein,et al. Relationship Between Insulin Sensitivity and Plasma Leptin Concentration in Lean and Obese Men , 1996, Diabetes.
[136] Yoshiya Tanaka,et al. Advanced Glycation End Products Induce Calcification of Vascular Smooth Muscle Cells through RAGE/p38 MAPK , 2009, Journal of Vascular Research.
[137] M. Budoff,et al. Fetuin-A is inversely associated with coronary artery calcification in community-living persons: the Multi-Ethnic Study of Atherosclerosis. , 2012, Clinical chemistry.
[138] Z. Massy,et al. High extracellular inorganic phosphate concentration inhibits RANK–RANKL signaling in osteoclast‐like cells , 2008, Journal of cellular physiology.
[139] P. Traldi,et al. Glyco-oxidation in diabetes and related diseases. , 2005, Clinica chimica acta; international journal of clinical chemistry.
[140] Sho-ichi Yamagishi,et al. Role of advanced glycation end products (AGEs) and receptor for AGEs (RAGE) in vascular damage in diabetes , 2011, Experimental Gerontology.
[141] P. Weissberg,et al. Osteo/Chondrocytic Transcription Factors and Their Target Genes Exhibit Distinct Patterns of Expression in Human Arterial Calcification , 2003, Arteriosclerosis, thrombosis, and vascular biology.
[142] J. Cauley,et al. Bone Mineral Density and Aortic Calcification: The Study of Osteoporotic Fractures , 1997, Journal of the American Geriatrics Society.
[143] A. Canfield,et al. Chondrogenic and Adipogenic Potential of Microvascular Pericytes , 2004, Circulation.
[144] E. Parati,et al. The postnatal rat aorta contains pericyte progenitor cells that form spheroidal colonies in suspension culture. , 2005, American journal of physiology. Cell physiology.
[145] C. Miao,et al. Adipokines in inflammation, insulin resistance and cardiovascular disease , 2011, Clinical and experimental pharmacology & physiology.
[146] H. Okayama,et al. Prevention of vascular injury by combination of an AT1 receptor blocker, olmesartan, with various calcium antagonists. , 2009, American journal of hypertension.
[147] J. Millán,et al. Upregulation of alkaline phosphatase and pyrophosphate hydrolysis: potential mechanism for uremic vascular calcification. , 2008, Kidney international.
[148] D. Towler. Vascular calcification: it's all the RAGE! , 2011, Arteriosclerosis, thrombosis, and vascular biology.
[149] E. Jimi,et al. Receptor Activator of NF-κB Ligand Stimulates Recruitment of SHP-1 to the Complex Containing TNFR-Associated Factor 6 That Regulates Osteoclastogenesis1 , 2003, The Journal of Immunology.
[150] S. Haffner,et al. Insulin-resistant prediabetic subjects have more atherogenic risk factors than insulin-sensitive prediabetic subjects: implications for preventing coronary heart disease during the prediabetic state. , 2000, Circulation.
[151] J. Golledge,et al. Osteoprotegerin, vascular calcification and atherosclerosis. , 2009, Atherosclerosis.
[152] Lisa Kolb,et al. Vascular ossification-calcification in metabolic syndrome, type 2 diabetes mellitus, chronic kidney disease, and calciphylaxis-calcific uremic arteriolopathy: the emerging role of sodium thiosulfate. , 2005, Cardiovascular diabetology.
[153] J. Millán,et al. Inactivation of two mouse alkaline phosphatase genes and establishment of a model of infantile hypophosphatasia , 1997, Developmental dynamics : an official publication of the American Association of Anatomists.
[154] Xianwu Li,et al. Role of the Sodium-Dependent Phosphate Cotransporter, Pit-1, in Vascular Smooth Muscle Cell Calcification , 2006, Circulation research.
[155] Andrea Rossi,et al. Aortic and Mitral Annular Calcifications Are Predictive of All-Cause and Cardiovascular Mortality in Patients With Type 2 Diabetes , 2012, Diabetes Care.
[156] C. Farquharson,et al. Comparative modelling of human PHOSPHO1 reveals a new group of phosphatases within the haloacid dehalogenase superfamily. , 2003, Protein engineering.
[157] E. Mohler,et al. Paradoxical Effects of Statins on Aortic Valve Myofibroblasts and Osteoblasts: Implications for End-Stage Valvular Heart Disease , 2005, Arteriosclerosis, thrombosis, and vascular biology.
[158] Roland Baron,et al. BMP‐2 Controls Alkaline Phosphatase Expression and Osteoblast Mineralization by a Wnt Autocrine Loop , 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[159] Yan Cai,et al. Endogenous aldosterone is involved in vascular calcification in rat , 2012, Experimental biology and medicine.
[160] A. Localio,et al. Plasma leptin levels are associated with coronary atherosclerosis in type 2 diabetes. , 2004, The Journal of clinical endocrinology and metabolism.
[161] C. Giachelli,et al. Elevated extracellular calcium levels induce smooth muscle cell matrix mineralization in vitro. , 2004, Kidney international.
[162] Y. Tintut,et al. Vascular calcification: mechanisms and clinical ramifications. , 2004, Arteriosclerosis, thrombosis, and vascular biology.
[163] M. Emoto,et al. Diabetes mellitus, aortic stiffness, and cardiovascular mortality in end-stage renal disease. , 2001, Journal of the American Society of Nephrology : JASN.
[164] M. Urina-Triana,et al. Use of Calcium Channel Blockers in Cardiovascular Risk Reduction , 2010, American journal of cardiovascular drugs : drugs, devices, and other interventions.
[165] M. McKee,et al. Endocrine Regulation of Energy Metabolism by the Skeleton , 2007, Cell.
[166] W. Haynes. Role of leptin in obesity‐related hypertension , 2005, Experimental physiology.
[167] J. Wozney,et al. Runx2 Is a Common Target of Transforming Growth Factor β1 and Bone Morphogenetic Protein 2, and Cooperation between Runx2 and Smad5 Induces Osteoblast-Specific Gene Expression in the Pluripotent Mesenchymal Precursor Cell Line C2C12 , 2000, Molecular and Cellular Biology.
[168] E. Slatopolsky,et al. Differential effects of vitamin D receptor activators on vascular calcification in uremic rats. , 2007, Kidney international.
[169] L. Lerman,et al. Patients with an HbA1c in the prediabetic and diabetic range have higher numbers of circulating cells with osteogenic and endothelial progenitor cell markers. , 2012, Journal of Clinical Endocrinology and Metabolism.
[170] E. Wright,et al. Oxidative stress in type 2 diabetes: the role of fasting and postprandial glycaemia , 2006, International journal of clinical practice.
[171] P. Kostenuik,et al. Inhibition of receptor activator of NF-kappaB ligand by denosumab attenuates vascular calcium deposition in mice. , 2009, The American journal of pathology.
[172] M. J. Ortuno,et al. BMP-2 Induces Osterix Expression through Up-regulation of Dlx5 and Its Phosphorylation by p38* , 2008, Journal of Biological Chemistry.
[173] J. Floege,et al. Fetuin-A (AHSG) prevents extraosseous calcification induced by uraemia and phosphate challenge in mice. , 2007, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
[174] I. Shapiro,et al. Induction of Apoptosis in Skeletal Tissues: Phosphate-Mediated Chick Chondrocyte Apoptosis is Calcium Dependent , 2003, Calcified Tissue International.
[175] A. Saremi,et al. Progression of Vascular Calcification Is Increased With Statin Use in the Veterans Affairs Diabetes Trial (VADT) , 2012, Diabetes Care.
[176] K. Sakhaee,et al. Lovastatin raises serum osteoprotegerin level in people with type 2 diabetic nephropathy. , 2010, Clinical biochemistry.
[177] H. Fleisch. Bisphosphonates: Mechanisms of Action , 1998 .
[178] H. Dietz,et al. Phenotypic Alteration of Vascular Smooth Muscle Cells Precedes Elastolysis in a Mouse Model of Marfan Syndrome , 2001, Circulation research.
[179] Melec G Zeadin,et al. Oxidized low‐density lipoprotein promotes osteoblast differentiation in primary cultures of vascular smooth muscle cells by up‐regulating Osterix expression in an Msx2‐dependent manner , 2011, Journal of cellular biochemistry.
[180] D. Towler,et al. Vascular calcification: the killer of patients with chronic kidney disease. , 2009, Journal of the American Society of Nephrology : JASN.
[181] F. Parhami,et al. High-Density Lipoprotein Regulates Calcification of Vascular Cells , 2002, Circulation research.
[182] D. Strunk,et al. Blood Monocytes Mimic Endothelial Progenitor Cells , 2006, Stem cells.
[183] Xianwu Li,et al. Regulation of Vascular Calcification Roles of Phosphate and Osteopontin , 2005 .
[184] Lei Chang,et al. Synthesis and evaluation of thiophenyl derivatives as inhibitors of alkaline phosphatase. , 2011, Bioorganic & medicinal chemistry letters.
[185] Y. Tintut,et al. Insulin-Like Growth Factor-I Regulates Proliferation and Osteoblastic Differentiation of Calcifying Vascular Cells via Extracellular Signal-Regulated Protein Kinase And Phosphatidylinositol 3-Kinase Pathways , 2005, Circulation research.
[186] James T. Willerson,et al. Transdifferentiation of Human Peripheral Blood CD34+-Enriched Cell Population Into Cardiomyocytes, Endothelial Cells, and Smooth Muscle Cells In Vivo , 2003, Circulation.
[187] Qingbo Xu,et al. Abundant progenitor cells in the adventitia contribute to atherosclerosis of vein grafts in ApoE-deficient mice. , 2004, The Journal of clinical investigation.
[188] J. Ruiz,et al. Non-enzymatic glycation of lipoprotein(a) in vitro and in vivo. , 1995, Atherosclerosis.
[189] E. Aikawa,et al. Cardiovascular calcification: an inflammatory disease. , 2011, Circulation journal : official journal of the Japanese Circulation Society.
[190] G. Schernthaner. Pleiotropic effects of thiazolidinediones on traditional and non‐traditional atherosclerotic risk factors , 2009, International journal of clinical practice.
[191] J. Ehrhardt,et al. Regulation of blood flow to the aortic media in dogs. , 1978, The Journal of clinical investigation.
[192] James O. Mudd,et al. Beyond low-density lipoprotein cholesterol: defining the role of low-density lipoprotein heterogeneity in coronary artery disease. , 2007, Journal of the American College of Cardiology.
[193] J. Skepper,et al. Acetylated Low-Density Lipoprotein Stimulates Human Vascular Smooth Muscle Cell Calcification by Promoting Osteoblastic Differentiation and Inhibiting Phagocytosis , 2002, Circulation.
[194] A. Goustin,et al. Ahsg-fetuin blocks the metabolic arm of insulin action through its interaction with the 95-kD β-subunit of the insulin receptor. , 2013, Cellular signalling.
[195] D. Towler,et al. The regulation of valvular and vascular sclerosis by osteogenic morphogens. , 2011, Circulation research.
[196] W. Friedrichs,et al. Human alpha 2-HS-glycoprotein/bovine fetuin homologue in mice: identification and developmental regulation of the gene. , 1992, Biochimica et biophysica acta.
[197] Z. Al-Aly,et al. Arterial calcification: a tumor necrosis factor-alpha mediated vascular Wnt-opathy. , 2008, Translational research : the journal of laboratory and clinical medicine.
[198] Su‐Li Cheng,et al. Msx2 promotes cardiovascular calcification by activating paracrine Wnt signals. , 2005, The Journal of clinical investigation.
[199] W D Wagner,et al. A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. , 1995, Arteriosclerosis, thrombosis, and vascular biology.
[200] Fotis Sotiropoulos,et al. Direction and magnitude of blood flow shear stresses on the leaflets of aortic valves: is there a link with valve calcification? , 2010, Journal of biomechanical engineering.
[201] B. Larijani,et al. Reduced serum osteocalcin concentrations are associated with type 2 diabetes mellitus and the metabolic syndrome components in postmenopausal women: the crosstalk between bone and energy metabolism , 2012, Journal of Bone and Mineral Metabolism.
[202] B. Kestenbaum,et al. Serum phosphorus concentrations and arterial stiffness among individuals with normal kidney function to moderate kidney disease in MESA. , 2009, Clinical journal of the American Society of Nephrology : CJASN.
[203] Yan Cai,et al. Insulin resistance induces medial artery calcification in fructose-fed rats , 2012, Experimental biology and medicine.
[204] A. Sniderman,et al. Hypertriglyceridemic HyperapoB: The Unappreciated Atherogenic Dyslipoproteinemia in Type 2 Diabetes Mellitus , 2001, Annals of Internal Medicine.
[205] C. Raymond,et al. Sodium thiosulfate, bisphosphonates, and cinacalcet for treatment of calciphylaxis. , 2008, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.
[206] H. Anderson,et al. Calcification in atherosclerosis. II. Animal studies. , 1986, Journal of experimental pathology.
[207] S. Kihara,et al. Adiponectin, an Adipocyte-Derived Plasma Protein, Inhibits Endothelial NF-&kgr;B Signaling Through a cAMP-Dependent Pathway , 2000, Circulation.
[208] A. Papavassiliou,et al. Adiponectin and cardiovascular disease: mechanisms and new therapeutic approaches. , 2012, Current Medicinal Chemistry.
[209] Yong Sun,et al. Runx2-Upregulated Receptor Activator of Nuclear Factor &kgr;B Ligand in Calcifying Smooth Muscle Cells Promotes Migration and Osteoclastic Differentiation of Macrophages , 2011, Arteriosclerosis, thrombosis, and vascular biology.
[210] P. Price,et al. The Amino Bisphosphonate Ibandronate Prevents Calciphylaxis in the Rat at Doses that Inhibit Bone Resorption , 2002, Calcified Tissue International.
[211] S. Mundlos,et al. Cbfa1, a Candidate Gene for Cleidocranial Dysplasia Syndrome, Is Essential for Osteoblast Differentiation and Bone Development , 1997, Cell.
[212] Gene Kim,et al. S100A12 in Vascular Smooth Muscle Accelerates Vascular Calcification in Apolipoprotein E–Null Mice by Activating an Osteogenic Gene Regulatory Program , 2011, Arteriosclerosis, thrombosis, and vascular biology.
[213] T. Adragão,et al. Non-Calcium-Containing Phosphate Binders: Comparing Efficacy, Safety, and Other Clinical Effects , 2012, Nephron Clinical Practice.
[214] R. Krauss. Heterogeneity of plasma low‐density lipoproteins and atherosclerosis risk , 1994, Current opinion in lipidology.
[215] P. Raggi,et al. Accelerated vascular calcification and relative hypoparathyroidism in incident haemodialysis diabetic patients receiving calcium binders. , 2006, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.