Implementation of Clinical Decision Support on Emergency Department Delivery of Human Rabies Immune Globulin

Key Points Question Is implementation of a rabies postexposure prophylaxis bundle, consisting of electronic health record enhancements, staff education, and patient education, associated with improved human rabies immune globulin (HRIG) patient selection and delivery in the emergency department? Findings In this quality improvement study that included 324 patients, the primary outcome of full adherence to 6 HRIG quality indicators increased from 37% preimplementation to 61% postimplementation. Meaning These results suggest that a rabies postexposure prophylaxis bundle was associated with a statistically significant improvement in HRIG patient selection and delivery in emergency departments across a health system.

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