Design and development of polymeric micelles with cleavable links for intracellular drug delivery
暂无分享,去创建一个
[1] Vladimir Torchilin,et al. Multifunctional and stimuli-sensitive pharmaceutical nanocarriers. , 2009, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
[2] Alexander V Kabanov,et al. Pluronic block copolymers: evolution of drug delivery concept from inert nanocarriers to biological response modifiers. , 2008, Journal of controlled release : official journal of the Controlled Release Society.
[3] A. R. Kulkarni,et al. Biodegradable polymeric nanoparticles as drug delivery devices. , 2001, Journal of controlled release : official journal of the Controlled Release Society.
[4] G. Pauletti,et al. Rapidly disassembling nanomicelles with disulfide-linked PEG shells for glutathione-mediated intracellular drug delivery. , 2011, Chemical communications.
[5] N. Rapoport. Physical stimuli-responsive polymeric micelles for anti-cancer drug delivery , 2007 .
[6] W. Degraff,et al. Selective modulation of glutathione levels in human normal versus tumor cells and subsequent differential response to chemotherapy drugs. , 1986, Cancer research.
[7] Yongfeng Zhou,et al. Bioreducible micelles self-assembled from amphiphilic hyperbranched multiarm copolymer for glutathione-mediated intracellular drug delivery. , 2011, Biomacromolecules.
[8] Hua Wei,et al. Thermo-sensitive polymeric micelles based on poly(N-isopropylacrylamide) as drug carriers , 2009 .
[9] K. Ulbrich,et al. Properties of HPMA copolymer-doxorubicin conjugates with pH-controlled activation: effect of polymer chain modification. , 2006, Journal of controlled release : official journal of the Controlled Release Society.
[10] Dong Wang,et al. Cellular processing of platinum anticancer drugs , 2005, Nature Reviews Drug Discovery.
[11] V. Bulmus,et al. Acid-labile core cross-linked micelles for pH-triggered release of antitumor drugs. , 2008, Biomacromolecules.
[12] Yuichi Yamasaki,et al. PEGylated Calcium Phosphate Nanocomposites as Smart Environment‐Sensitive Carriers for siRNA Delivery , 2009 .
[13] J. Kong,et al. pH and reduction dual-sensitive copolymeric micelles for intracellular doxorubicin delivery. , 2011, Biomacromolecules.
[14] F. Bressolle,et al. Cisplatin-induced renal toxicity and toxicity-modulating strategies: a review , 2004, Cancer Chemotherapy and Pharmacology.
[15] D. Schmaljohann. Thermo- and pH-responsive polymers in drug delivery. , 2006, Advanced drug delivery reviews.
[16] K. Nagayama,et al. Envelope-type lipid nanoparticles incorporating a short PEG-lipid conjugate for improved control of intracellular trafficking and transgene transcription. , 2009, Biomaterials.
[17] Wenguang Liu,et al. Degradable disulfide core-cross-linked micelles as a drug delivery system prepared from vinyl functionalized nucleosides via the RAFT process. , 2008, Biomacromolecules.
[18] B. Lai,et al. The fate of platinum(II) and platinum(IV) anti-cancer agents in cancer cells and tumours. , 2006, Journal of structural biology.
[19] Jin Huang,et al. Fabrication of reduction-degradable micelle based on disulfide-linked graft copolymer-camptothecin conjugate for enhancing solubility and stability of camptothecin , 2010 .
[20] Yuting Li,et al. RAFT Synthesis of a Thermally Responsive ABC Triblock Copolymer Incorporating N-Acryloxysuccinimide for Facile in Situ Formation of Shell Cross-Linked Micelles in Aqueous Media† , 2006 .
[21] H Akita,et al. Development of a novel systemic gene delivery system for cancer therapy with a tumor-specific cleavable PEG-lipid , 2007, Gene Therapy.
[22] C. Giandomenico,et al. Current status of platinum-based antitumor drugs. , 1999, Chemical reviews.
[23] Stephen J Lippard,et al. Direct cellular responses to platinum-induced DNA damage. , 2007, Chemical reviews.
[24] R. Zhuo,et al. Preparation of novel ferrocene-based shell cross-linked thermoresponsive hybrid micelles with antitumor efficacy. , 2010, The journal of physical chemistry. B.
[25] Freya Q. Schafer,et al. Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple. , 2001, Free radical biology & medicine.
[26] Kazunori Kataoka,et al. PEGylated Nanoparticles for Biological and Pharmaceutical Applications , 2003 .
[27] Wenbin Lin,et al. Polysilsesquioxane nanoparticles for targeted platin-based cancer chemotherapy by triggered release. , 2011, Angewandte Chemie.
[28] Xiabin Jing,et al. Synthesis and characterization of the paclitaxel/MPEG-PLA block copolymer conjugate. , 2005, Biomaterials.
[29] Chun Xing Li,et al. Polymer-drug conjugates: recent development in clinical oncology. , 2008, Advanced drug delivery reviews.
[30] C. Supuran,et al. Hypoxia activates the capacity of tumor‐associated carbonic anhydrase IX to acidify extracellular pH , 2004, FEBS letters.
[31] You Han Bae,et al. Super pH-sensitive multifunctional polymeric micelle. , 2005, Nano letters.
[32] I Mellman,et al. Acidification of the endocytic and exocytic pathways. , 1986, Annual review of biochemistry.
[33] E. Schacht,et al. Use of Block Copolymers of Poly(Ortho Esters) and Poly (Ethylene Glycol) Micellar Carriers as Potential Tumour Targeting Systems , 2003, Journal of drug targeting.
[34] Angel Ortega,et al. Glutathione in Cancer Biology and Therapy , 2006, Critical reviews in clinical laboratory sciences.
[35] S. Standley,et al. Fully acid-degradable biocompatible polyacetal microparticles for drug delivery. , 2008, Bioconjugate chemistry.
[36] J. Cidlowski,et al. Apoptosis and glutathione: beyond an antioxidant , 2009, Cell Death and Differentiation.
[37] T. Hambley,et al. Studies of the binding of a series of platinum(IV) complexes to plasma proteins. , 2002, Journal of inorganic biochemistry.
[38] F. Muggia. Doxil in breast cancer. , 1998, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[39] M. Jakupec,et al. Recent developments in the field of tumor-inhibiting metal complexes. , 2003, Current pharmaceutical design.
[40] Roey J. Amir,et al. Enzymatically triggered self-assembly of block copolymers. , 2009, Journal of the American Chemical Society.
[41] R. Murphy,et al. Regulation of endocytic pH by the Na+,K+-ATPase in living cells. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[42] Yang Li,et al. Shell-detachable micelles based on disulfide-linked block copolymer as potential carrier for intracellular drug delivery. , 2009, Bioconjugate chemistry.
[43] R. Zhuo,et al. Preparation of Shell Cross-Linked Thermoresponsive Micelles as well as Hollow Spheres Based on P(NIPAAm-co-HMAAm-co-MPMA)-b-PCL , 2008 .
[44] J. Fréchet,et al. pH-Responsive copolymer assemblies for controlled release of doxorubicin. , 2005, Bioconjugate chemistry.
[45] S. Brocchini,et al. Pendent Chain Functionalized Polyacetals That Display pH-Dependent Degradation: A Platform for the Development of Novel Polymer Therapeutics , 2002 .
[46] Haiqing Dong,et al. Engineering of a novel pluronic F127/graphene nanohybrid for pH responsive drug delivery. , 2012, Journal of biomedical materials research. Part A.
[47] T. Shi,et al. Reduction of trans-dichloro- and trans-dibromo-tetracyanoplatinate(IV) by L-methionine , 1997 .
[48] U. Schubert,et al. Poly(ethylene glycol) in drug delivery: pros and cons as well as potential alternatives. , 2010, Angewandte Chemie.
[49] Atsushi Harada,et al. Design of environment-sensitive supramolecular assemblies for intracellular drug delivery: polymeric micelles that are responsive to intracellular pH change. , 2003, Angewandte Chemie.
[50] Gert Storm,et al. Sheddable Coatings for Long-Circulating Nanoparticles , 2007, Pharmaceutical Research.
[51] Xuesi Chen,et al. A novel polymer-paclitaxel conjugate based on amphiphilic triblock copolymer. , 2007, Journal of controlled release : official journal of the Controlled Release Society.
[52] R. Narain,et al. Degradable thermoresponsive core cross-linked micelles: fabrication, surface functionalization, and biorecognition. , 2009, Langmuir : the ACS journal of surfaces and colloids.
[53] Yujiang Fan,et al. Disassemblable micelles based on reduction-degradable amphiphilic graft copolymers for intracellular delivery of doxorubicin. , 2010, Biomaterials.
[54] Jean Campbell,et al. Bioinspired pH-responsive polymers for the intracellular delivery of biomolecular drugs. , 2003, Bioconjugate chemistry.
[55] Jayant Khandare,et al. Polymer-drug conjugates: Progress in polymeric prodrugs , 2006 .
[56] R. Zhuo,et al. Synthesis and characterization of thermoresponsive polymers containing reduction-sensitive disulfide linkage , 2009 .
[57] Mauro Ferrari,et al. Nanomedicine--challenge and perspectives. , 2009, Angewandte Chemie.
[58] K. Ulbrich,et al. Doxorubicin bound to a HPMA copolymer carrier through hydrazone bond is effective also in a cancer cell line with a limited content of lysosomes. , 2001, Journal of controlled release : official journal of the Controlled Release Society.
[59] Vladimir P Torchilin,et al. Recent approaches to intracellular delivery of drugs and DNA and organelle targeting. , 2006, Annual review of biomedical engineering.
[60] Gregory S Karczmar,et al. MRI of the tumor microenvironment , 2002, Journal of magnetic resonance imaging : JMRI.
[61] L. Kèlland,et al. The resurgence of platinum-based cancer chemotherapy , 2007, Nature Reviews Cancer.
[62] Q. Zhang,et al. Biodegradable block copolymer micelles with thiol-responsive sheddable coronas. , 2011, Biomacromolecules.
[63] R. Duncan. The dawning era of polymer therapeutics , 2003, Nature Reviews Drug Discovery.
[64] H. T. Duong,et al. Micelles with surface conjugated RGDpeptide and crosslinked polyurea core viaRAFT polymerization , 2010 .
[65] X. Qu,et al. Preparation of multifunctional drug carrier for tumor-specific uptake and enhanced intracellular delivery through the conjugation of weak acid labile linker. , 2009, Bioconjugate chemistry.
[66] J. Fréchet,et al. A new approach towards acid sensitive copolymer micelles for drug delivery. , 2003, Chemical communications.
[67] M. Hall,et al. Platinum(IV) antitumour compounds: their bioinorganic chemistry , 2002 .
[68] Yi-Yan Yang,et al. Core-shell-corona micelle stabilized by reversible cross-linkage for intracellular drug delivery. , 2010, Macromolecular rapid communications.
[69] Alexander V Kabanov,et al. Polymer genomics: an insight into pharmacology and toxicology of nanomedicines. , 2006, Advanced drug delivery reviews.
[70] T. A. Hatton,et al. Complexation and release of doxorubicin from its complexes with pluronic P85-b-poly(acrylic acid) block copolymers. , 2007, Journal of controlled release : official journal of the Controlled Release Society.
[71] C. Marquis,et al. Acid Degradable and Biocompatible Polymeric Nanoparticles for the Potential Codelivery of Therapeutic Agents , 2011 .
[72] T. Park,et al. Doxorubicin-conjugated biodegradable polymeric micelles having acid-cleavable linkages. , 2002, Journal of controlled release : official journal of the Controlled Release Society.
[73] Liangfang Zhang,et al. Polymer--cisplatin conjugate nanoparticles for acid-responsive drug delivery. , 2010, ACS nano.
[74] Yan Xu,et al. Reduction-sensitive reversibly crosslinked biodegradable micelles for triggered release of doxorubicin. , 2009, Macromolecular bioscience.
[75] Michele Peyrone. Ueber die Einwirkung des Ammoniaks auf Platinchlorür , 1844 .
[76] Kazunori Kataoka,et al. Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property: tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy. , 2005, Bioconjugate chemistry.
[77] Zhiyuan Zhong,et al. Glutathione-responsive nano-vehicles as a promising platform for targeted intracellular drug and gene delivery. , 2011, Journal of controlled release : official journal of the Controlled Release Society.
[78] J. Fréchet,et al. Stimuli-responsive supramolecular assemblies of linear-dendritic copolymers. , 2004, Journal of the American Chemical Society.
[79] Chun Wang,et al. Block copolymer micelles with acid-labile ortho ester side-chains: Synthesis, characterization, and enhanced drug delivery to human glioma cells. , 2011, Journal of controlled release : official journal of the Controlled Release Society.
[80] T. Ren,et al. Shell-sheddable micelles based on star-shaped poly(ε-caprolactone)-SS-poly(ethyl glycol) copolymer for intracellular drug release , 2011 .
[81] P. de Souza,et al. Core-cross-linked micelles synthesized by clicking bifunctional Pt(IV) anticancer drugs to isocyanates. , 2010, Biomacromolecules.
[82] Wei Huang,et al. Redox-responsive polyphosphate nanosized assemblies: a smart drug delivery platform for cancer therapy. , 2011, Biomacromolecules.
[83] N. Murthy,et al. Disulfide-Crosslinked Polyion Micelles for Delivery of Protein Therapeutics , 2009, Annals of Biomedical Engineering.
[84] Xinyuan Zhu,et al. Oxime linkage: a robust tool for the design of pH-sensitive polymeric drug carriers. , 2011, Biomacromolecules.
[85] Kai Licha,et al. Development of efficient acid cleavable multifunctional prodrugs derived from dendritic polyglycerol with a poly(ethylene glycol) shell. , 2011, Journal of controlled release : official journal of the Controlled Release Society.
[86] Jean Campbell,et al. Design and synthesis of pH-responsive polymeric carriers that target uptake and enhance the intracellular delivery of oligonucleotides. , 2003, Journal of controlled release : official journal of the Controlled Release Society.
[87] Daniel W. Pack,et al. Design and development of polymers for gene delivery , 2005, Nature Reviews Drug Discovery.
[88] C. Won,et al. PEG-modified biopharmaceuticals , 2009 .
[89] Jiehua Li,et al. The degradation and biocompatibility of pH-sensitive biodegradable polyurethanes for intracellular multifunctional antitumor drug delivery. , 2012, Biomaterials.
[90] G. Sahay,et al. Polymeric micelles with ionic cores containing biodegradable cross-links for delivery of chemotherapeutic agents. , 2010, Biomacromolecules.
[91] J. Kopeček,et al. Intracellular targeting of polymer-bound drugs for cancer chemotherapy. , 2005, Advanced drug delivery reviews.
[92] Robert Gurny,et al. Poly(ortho esters): synthesis, characterization, properties and uses. , 2002, Advanced drug delivery reviews.
[93] S. Thayumanavan,et al. Redox-sensitive disassembly of amphiphilic copolymer based micelles. , 2010, Langmuir : the ACS journal of surfaces and colloids.
[94] Vladimir P Torchilin,et al. Micelles from lipid derivatives of water-soluble polymers as delivery systems for poorly soluble drugs. , 2004, Advanced drug delivery reviews.
[95] W. Guo,et al. Endosomal pH-activatable poly(ethylene oxide)-graft-doxorubicin prodrugs: synthesis, drug release, and biodistribution in tumor-bearing mice. , 2011, Biomacromolecules.
[96] K. Ulbrich,et al. New HPMA copolymer-based drug carriers with covalently bound hydrophobic substituents for solid tumour targeting. , 2008, Journal of controlled release : official journal of the Controlled Release Society.
[97] R. Langer,et al. Drug delivery and targeting. , 1998, Nature.
[98] S. Armes,et al. Synthesis of Reversible Shell Cross-Linked Micelles For Controlled Release of Bioactive Agents , 2006 .
[99] K. Kataoka,et al. Block copolymer micelles for drug delivery: design, characterization and biological significance. , 2001, Advanced drug delivery reviews.
[100] Craig J Hawker,et al. Cross-linked block copolymer micelles: functional nanostructures of great potential and versatility. , 2006, Chemical Society reviews.
[101] Xian‐Zheng Zhang,et al. Core-shell nanosized assemblies mediated by the alpha-beta cyclodextrin dimer with a tumor-triggered targeting property. , 2010, ACS nano.
[102] Donglu Shi,et al. Self-assembling nanomicelles of a novel camptothecin prodrug engineered with a redox-responsive release mechanism. , 2011, Chemical communications.
[103] Wentao Lu,et al. Acid-activatable prodrug nanogels for efficient intracellular doxorubicin release. , 2011, Biomacromolecules.
[104] Zhongfan Jia,et al. One-pot conversion of RAFT-generated multifunctional block copolymers of HPMA to doxorubicin conjugated acid- and reductant-sensitive crosslinked micelles. , 2008, Biomacromolecules.
[105] R. Franco,et al. The central role of glutathione in the pathophysiology of human diseases , 2007, Archives of physiology and biochemistry.
[106] F. Meng,et al. Biodegradable micelles with sheddable poly(ethylene glycol) shells for triggered intracellular release of doxorubicin. , 2009, Biomaterials.
[107] Xianglong Hu,et al. Multifunctional pH-disintegrable micellar nanoparticles of asymmetrically functionalized β-cyclodextrin-based star copolymer covalently conjugated with doxorubicin and DOTA-Gd moieties. , 2012, Biomaterials.
[108] S Thayumanavan,et al. Multi-stimuli sensitive amphiphilic block copolymer assemblies. , 2009, Journal of the American Chemical Society.
[109] K. Ulbrich,et al. Polymeric micellar pH-sensitive drug delivery system for doxorubicin. , 2005, Journal of controlled release : official journal of the Controlled Release Society.
[110] R. Zhuo,et al. PEG-detachable and acid-labile cross-linked micelles based on orthoester linked graft copolymer for paclitaxel release , 2011, Nanotechnology.
[111] Xiabin Jing,et al. Biodegradable block copolymer-doxorubicin conjugates via different linkages: preparation, characterization, and in vitro evaluation. , 2010, Biomacromolecules.
[112] Sylvia Notenboom,et al. Glutathione dysregulation and the etiology and progression of human diseases , 2009, Biological chemistry.
[113] Jean M. J. Fréchet,et al. Synthesis and Degradation of pH-Sensitive Linear Poly(amidoamine)s , 2007 .
[114] H. Maeda,et al. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. , 2000, Journal of controlled release : official journal of the Controlled Release Society.
[115] T. Ren,et al. Sheddable micelles based on disulfide-linked hybrid PEG-polypeptide copolymer for intracellular drug delivery , 2011 .
[116] Zhiyuan Zhong,et al. Stimuli-responsive polymersomes for programmed drug delivery. , 2009, Biomacromolecules.
[117] Gaojian Chen,et al. Thiol-yne and thiol-ene "click" chemistry as a tool for a variety of platinum drug delivery carriers, from statistical copolymers to crosslinked micelles. , 2011, Biomacromolecules.
[118] C. van Nostrum,et al. Triggered destabilisation of polymeric micelles and vesicles by changing polymers polarity: an attractive tool for drug delivery. , 2007, Journal of controlled release : official journal of the Controlled Release Society.
[119] Zhiyuan Zhong,et al. pH-responsive biodegradable micelles based on acid-labile polycarbonate hydrophobe: synthesis and triggered drug release. , 2009, Biomacromolecules.
[120] Maohong Fan,et al. Prodrugs forming high drug loading multifunctional nanocapsules for intracellular cancer drug delivery. , 2010, Journal of the American Chemical Society.
[121] Xiaojun Cai,et al. Effective gene delivery using stimulus-responsive catiomer designed with redox-sensitive disulfide and acid-labile imine linkers. , 2012, Biomacromolecules.
[122] Shuming Nie,et al. Understanding and overcoming major barriers in cancer nanomedicine. , 2010, Nanomedicine.
[123] Ruth Duncan,et al. Polymer conjugates as anticancer nanomedicines , 2006, Nature Reviews Cancer.
[124] N. Murthy,et al. Polyketal nanoparticles: a new pH-sensitive biodegradable drug delivery vehicle. , 2005, Bioconjugate chemistry.
[125] F. Zunino,et al. New Cisplatin Analogues—On the Way to Better Antitumor Agents , 1987 .
[126] Joel A Swanson,et al. Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities. , 2003, Advanced drug delivery reviews.
[127] R. Shunmugam,et al. Norbornene derived doxorubicin copolymers as drug carriers with pH responsive hydrazone linker. , 2012, Biomacromolecules.
[128] X. Jiang,et al. Facile Fabrication of Reversible Core Cross-Linked Micelles Possessing Thermosensitive Swellability , 2007 .
[129] F. Szoka,et al. Soluble polymer carriers for the treatment of cancer: the importance of molecular architecture. , 2009, Accounts of chemical research.
[130] Sung Eun Kim,et al. Disulfide-cross-linked PEG-poly(amino acid)s copolymer micelles for glutathione-mediated intracellular drug delivery. , 2008, Chemical communications.
[131] G. Pasut,et al. Polymer-drug conjugation, recent achievements and general strategies , 2007 .
[132] Ru Cheng,et al. Shell-sheddable micelles based on dextran-SS-poly(epsilon-caprolactone) diblock copolymer for efficient intracellular release of doxorubicin. , 2010, Biomacromolecules.
[133] Maria Kavallaris,et al. Acid-cleavable polymeric core-shell particles for delivery of hydrophobic drugs. , 2006, Journal of controlled release : official journal of the Controlled Release Society.
[134] V. Bulmus,et al. Block Co-polymer Nanoparticles with Degradable Cross-Linked Core and Low-Molecular-Weight PEG Corona for Anti-tumour Drug Delivery , 2011, Journal of biomaterials science. Polymer edition.