Three‐dimensional (3D‐) reconstruction of M cells in rabbit peyer's patches: Definition of the intraepithelial compartment of the follicle‐associated epithelium

One of the major cell components of the rabbit follicle‐associated epithelium is represented by the M cells. M cells are able to harbour variable amounts of immunocompetent cells inside peculiar invaginations of their basolateral cytoplasmic membrane, currently referred to as “pockets.” This study provides a description of the exact spatial relationships between the M cells and the cells harboured in these so‐called “pockets.”

[1]  E. Bertelli,et al.  Uptake of a gram-positive bacterium (Streptococcus pneumoniae R36a) by the M cells of rabbit Peyer's patches. , 1995, Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft.

[2]  E. Bertelli,et al.  A morphological study of the lymphocyte traffic in Peyer's patches after an in vivo antigenic stimulation , 1994, The Anatomical record.

[3]  Y. Fujimura,et al.  Immunohistochemical localisation of intercellular adhesion molecule-1 in follicle associated epithelium of Peyer's patches. , 1994, Gut.

[4]  J. Kraehenbuhl,et al.  The role of transepithelial transport by M cells in microbial invasion and host defense , 1993, Journal of Cell Science.

[5]  A. Gebert,et al.  Differential binding of lectins to M cells and enterocytes in the rabbit cecum. , 1993, Gastroenterology.

[6]  D. Mendrick,et al.  Rat intestinal M cells contain acidic endosomal-lysosomal compartments and express class II major histocompatibility complex determinants. , 1993, Gastroenterology.

[7]  J. Pappo,et al.  Follicle epithelial M cells are a source of interleukin-1 in Peyer's patches. , 1993, Immunology.

[8]  J. Kraehenbuhl,et al.  Molecular and cellular basis of immune protection of mucosal surfaces. , 1992, Physiological reviews.

[9]  S. Targan.  The Lamina Propria: a Dynamic, Complex Mucosal Compartment An Overview , 1992, Annals of the New York Academy of Sciences.

[10]  J. Kay,et al.  Antigen processing for presentation by class II major histocompatibility complex requires cleavage by cathepsin E , 1992, European journal of immunology.

[11]  H. Ohtani,et al.  HLA‐DR Expression on M Cells Overlying Peyer's Patches is a Common Feature of Human Small Intestine , 1991, Acta pathologica japonica.

[12]  T. Murakami,et al.  Organization of the reticular network of rabbit Peyer's patches , 1991, The Anatomical record.

[13]  J. Pappo,et al.  Phenotypically distinct subpopulations of T cells in domes and M-cell pockets of rabbit gut-associated lymphoid tissues. , 1990, Immunology.

[14]  H. Hahn,et al.  Involvement of M cells in the bacterial invasion of Peyer's patches: a common mechanism shared by Yersinia enterocolitica and other enteroinvasive bacteria. , 1990, Gut.

[15]  J. Warchoł,et al.  Poliovirus type 1 enters the human host through intestinal M cells. , 1990, Gastroenterology.

[16]  D. Keren,et al.  Role of M cells in initial antigen uptake and in ulcer formation in the rabbit intestinal loop model of shigellosis , 1989, Infection and immunity.

[17]  P. Brandtzaeg,et al.  T cell distribution is different in follicle-associated epithelium of human Peyer's patches and villous epithelium. , 1988, Clinical and experimental immunology.

[18]  J. Parker,et al.  Selective association and transport of Campylobacter jejuni through M cells of rabbit Peyer's patches. , 1988, Canadian journal of microbiology.

[19]  S. Kohbata,et al.  Cytopathogenic Effect of Salmonella typhi GIFU 10007 on M cells of Murine Ileal Peyer's Patches in Ligated Ileal Loops: An Ultrastructural Study , 1986, Microbiology and immunology.

[20]  T. Ermak,et al.  Differential distribution of lymphocytes and accessory cells in mouse Peyer's patches , 1986, The Anatomical record.

[21]  W. Cray,et al.  M cell transport of Vibrio cholerae from the intestinal lumen into Peyer's patches: a mechanism for antigen sampling and for microbial transepithelial migration. , 1986, The Journal of infectious diseases.

[22]  P. Isaacson,et al.  Human Peyer's patches: an immunohistochemical study. , 1986, Gut.

[23]  S. Durum,et al.  Interleukin 1: an immunological perspective. , 1985, Annual review of immunology.

[24]  J. S. Trier,et al.  Structure, distribution, and origin of M cells in Peyer's patches of mouse ileum. , 1984, Gastroenterology.

[25]  J. Wolf,et al.  The membranous epithelial (M) cell and the mucosal immune system. , 1984, Annual review of medicine.

[26]  R. Finberg,et al.  Determinants of reovirus interaction with the intestinal M cells and absorptive cells of murine intestine. , 1983, Gastroenterology.

[27]  J. Cantey,et al.  Specific adherence of Escherichia coli (strain RDEC-1) to membranous (M) cells of the Peyer's patch in Escherichia coli diarrhea in the rabbit. , 1983, The Journal of clinical investigation.

[28]  R. Owen.  Sequential uptake of horseradish peroxidase by lymphoid follicle epithelium of Peyer's patches in the normal unobstructed mouse intestine: an ultrastructural study. , 1977, Gastroenterology.

[29]  J. Bienenstock,et al.  A morphologic study of rabbit bronchial lymphoid aggregates and lymphoepithelium. , 1976, Laboratory investigation; a journal of technical methods and pathology.

[30]  A. Jones,et al.  Epithelial cell specialization within human Peyer's patches: an ultrastructural study of intestinal lymphoid follicles. , 1974, Gastroenterology.

[31]  M. Cooper,et al.  Pinocytosis by epithelium associated with lymphoid follicles in the bursa of Fabricius, appendix, and Peyer's patches. An electron microscopic study. , 1973, The American journal of anatomy.