Gene regulatory networks and network models in development and evolution

The passion, energy, and intellectual rigor that the late Eric Davidson brought to science transformed fields and the lives of many scientists working in them. Key among his many contributions was developing a testable framework and global approach to understanding the mechanics of gene regulation and development. For several decades, Davidson and his colleagues developed the tools, concepts, and approaches that led to a conceptual revolution in our understanding of the role of circuits of interacting genes, regulatory elements, and transcription factors in the differentiation of cells, tissues, … [↵][1]1Email: nshubin{at}uchicago.edu. [1]: #xref-corresp-1-1

[1]  Denis Thieffry,et al.  Logical modeling of lymphoid and myeloid cell specification and transdifferentiation , 2017, Proceedings of the National Academy of Sciences.

[2]  Chen Ran,et al.  Drosophila Pax6 promotes development of the entire eye-antennal disc, thereby ensuring proper adult head formation , 2017, Proceedings of the National Academy of Sciences.

[3]  Brian D. Slaughter,et al.  Dynamic regulation of Nanog and stem cell-signaling pathways by Hoxa1 during early neuro-ectodermal differentiation of ES cells , 2017, Proceedings of the National Academy of Sciences.

[4]  S. Shvartsman,et al.  Gene regulation during Drosophila eggshell patterning , 2017, Proceedings of the National Academy of Sciences.

[5]  Isabelle S. Peter,et al.  Assessing regulatory information in developmental gene regulatory networks , 2017, Proceedings of the National Academy of Sciences.

[6]  A. Ciau-Uitz,et al.  Dissecting BMP signaling input into the gene regulatory networks driving specification of the blood stem cell lineage , 2017, Proceedings of the National Academy of Sciences.

[7]  M. Buckingham Gene regulatory networks and cell lineages that underlie the formation of skeletal muscle , 2017, Proceedings of the National Academy of Sciences.

[8]  Berthold Göttgens,et al.  Reconstructing blood stem cell regulatory network models from single-cell molecular profiles , 2017 .

[9]  V. Hinman,et al.  Genome-wide use of high- and low-affinity Tbrain transcription factor binding sites during echinoderm development , 2017, Proceedings of the National Academy of Sciences.

[10]  C. Whittle,et al.  Causes and evolutionary consequences of primordial germ-cell specification mode in metazoans , 2017, Proceedings of the National Academy of Sciences.

[11]  Patrick T McGrath,et al.  Applying gene regulatory network logic to the evolution of social behavior , 2017, Proceedings of the National Academy of Sciences.

[12]  V. Hinman,et al.  Paleogenomics of echinoids reveals an ancient origin for the double-negative specification of micromeres in sea urchins , 2017, Proceedings of the National Academy of Sciences.

[13]  Detlev Arendt,et al.  Whole-organism cellular gene-expression atlas reveals conserved cell types in the ventral nerve cord of Platynereis dumerilii , 2017, Proceedings of the National Academy of Sciences.

[14]  William J R Longabaugh,et al.  Bcl11b and combinatorial resolution of cell fate in the T-cell gene regulatory network , 2017, Proceedings of the National Academy of Sciences.