Developmental changes in refractoriness of the neuromagnetic M100 in children

CONSIDERABLE evidence exists for developmental changes in latency and amplitude of the auditory evoked potential termed N100. However, it is widely recognized that the N100 wave comprises multiple, temporally overlapping neural generators, and few data are available addressing either individual generator development or mechanisms behind such change. Using magnetoencelphalographic (MEG) measurements of the magnetic analog of the N100 termed the M100, which derives primarily from supra-temporal auditory generators, it is demonstrated here that changes in the response of that waveform to manipulation of interstimulus interval (ISI) occur between the ages of 6 and 18 years of age.

[1]  David Wechsler,et al.  Wechsler Intelligence Scale for Children; manual. , 1949 .

[2]  P. Yakovlev,et al.  The myelogenetic cycles of regional maturation of the brain , 1967 .

[3]  Echoic memory processes in good and poor readers. , 1986, Journal of experimental psychology. Learning, memory, and cognition.

[4]  N. Cowan,et al.  Temporal properties of memory for speech in preschool children , 1986, Memory & cognition.

[5]  J. H. Daruna,et al.  Development of the late components of auditory brain potentials from early childhood to adulthood. , 1987, Electroencephalography and clinical neurophysiology. Supplement.

[6]  T. Picton,et al.  The N1 wave of the human electric and magnetic response to sound: a review and an analysis of the component structure. , 1987, Psychophysiology.

[7]  Daruna Jh,et al.  Development of the late components of auditory brain potentials from early childhood to adulthood. , 1987 .

[8]  D. Molfese,et al.  Right-hemisphere responses from preschool children to temporal cues to speech and nonspeech materials: Electrophysiological correlates , 1988, Brain and Language.

[9]  C. Raynaud,et al.  Magnetic resonance imaging of the pediatric brain , 1990 .

[10]  L. Kaufman,et al.  Behavioral lifetime of human auditory sensory memory predicted by physiological measures. , 1992, Science.

[11]  N. Cowan,et al.  Developmental increase in the duration of memory for tone pitch. , 1994 .

[12]  I. Tonnquist-Uhlén,et al.  Topography of auditory evoked long-latency potentials in normal children, with particular reference to the N1 component. , 1995, Electroencephalography and clinical neurophysiology.