Abstract The existence of a valuable historical heritage of the Medieval age in Bologna has motivated a deeper study on the seismic behaviour of the Asinelli Tower, which, beyond being the town symbol, has a structural configuration prone to seismic damage. Accordingly, in the present paper, the seismicity of Bologna is reviewed and a synthesis of the damage observed in the urban area, based on an accurate historical research, is given, with the objective of evaluating the behavior of the Asinelli Tower within the framework of the effects localized in the municipality. An assessment of the tower's stability with respect to compatible seismic events, at least qualitatively, with the region seismicity is then carried out by means of a non-linear dynamic analysis on a simplified model.