Autophagy links inflammasomes to atherosclerotic progression.
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M. Kastan | H. Virgin | Seungmin Hwang | Haitao Wen | J. Ting | C. Semenkovich | B. Razani | T. Coleman | Chu Feng | Roy Emanuel
[1] Robert Clarke,et al. Guidelines for the use and interpretation of assays for monitoring autophagy , 2012 .
[2] V. Deretic,et al. Autophagy‐based unconventional secretory pathway for extracellular delivery of IL‐1β , 2011, The EMBO journal.
[3] J. Tschopp,et al. The inflammasome: an integrated view , 2011, Immunological reviews.
[4] G. Dorn,et al. Fatty Acid Synthase Modulates Homeostatic Responses to Myocardial Stress* , 2011, The Journal of Biological Chemistry.
[5] M. Behlke,et al. Small nucleolar RNAs U32a, U33, and U35a are critical mediators of metabolic stress. , 2011, Cell metabolism.
[6] Y. Marcel,et al. Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipase. , 2011, Cell metabolism.
[7] Seth L Masters,et al. The Inflammasome in Atherosclerosis and Type 2 Diabetes , 2011, Science Translational Medicine.
[8] Denis Gris,et al. Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling , 2011, Nature Immunology.
[9] G. Bhanot,et al. Autophagy Suppresses Tumorigenesis through Elimination of p62 , 2011, Cell.
[10] Haitao Wen,et al. The inflammasome NLRs in immunity, inflammation, and associated diseases. , 2011, Annual review of immunology.
[11] V. Dixit,et al. Mitochondrial reactive oxygen species drive proinflammatory cytokine production , 2011, The Journal of experimental medicine.
[12] S. Ryter,et al. Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. , 2011, Nature immunology.
[13] H. Virgin,et al. Autophagy in immunity and inflammation , 2011, Nature.
[14] Egil Lien,et al. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals , 2010, Nature.
[15] P. Kovanen,et al. Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation , 2010, PloS one.
[16] J. Schneider,et al. Macrophage Fatty-acid Synthase Deficiency Decreases Diet-induced Atherosclerosis* , 2010, The Journal of Biological Chemistry.
[17] Kate Schroder,et al. The NLRP3 Inflammasome: A Sensor for Metabolic Danger? , 2010, Science.
[18] Randall C. Thompson,et al. Computed tomographic assessment of atherosclerosis in ancient Egyptian mummies. , 2009, JAMA.
[19] D. Praticò,et al. Low‐dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptor , 2009, British journal of pharmacology.
[20] M. Huang,et al. Critical Role of Apoptotic Speck Protein Containing a Caspase Recruitment Domain (ASC) and NLRP3 in Causing Necrosis and ASC Speck Formation Induced by Porphyromonas gingivalis in Human Cells1 , 2009, The Journal of Immunology.
[21] J. Satsangi. Faculty Opinions recommendation of Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. , 2008 .
[22] K. Rock,et al. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization , 2008, Nature Immunology.
[23] D. Teupser,et al. Prevention of atherosclerosis by the mTOR inhibitor everolimus in LDLR-/- mice despite severe hypercholesterolemia. , 2008, Atherosclerosis.
[24] John L Cleveland,et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes , 2008, Autophagy.
[25] C. Thompson,et al. Autophagy: basic principles and relevance to disease. , 2008, Annual review of pathology.
[26] Guido Kroemer,et al. Autophagy in the Pathogenesis of Disease , 2008, Cell.
[27] Masaaki Komatsu,et al. Homeostatic Levels of p62 Control Cytoplasmic Inclusion Body Formation in Autophagy-Deficient Mice , 2007, Cell.
[28] C. Leeuwenburgh,et al. Autophagy in the heart and liver during normal aging and calorie restriction. , 2007, Rejuvenation research.
[29] Guido Kroemer,et al. Self-eating and self-killing: crosstalk between autophagy and apoptosis , 2007, Nature Reviews Molecular Cell Biology.
[30] J. Richardson,et al. Cardiac autophagy is a maladaptive response to hemodynamic stress. , 2007, The Journal of clinical investigation.
[31] P. Seglen,et al. How Shall I Eat Thee? , 2007, Autophagy.
[32] Yasushi Matsumura,et al. The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress , 2007, Nature Medicine.
[33] Hideyuki Okano,et al. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice , 2006, Nature.
[34] Masaaki Komatsu,et al. Loss of autophagy in the central nervous system causes neurodegeneration in mice , 2006, Nature.
[35] W. Jerome,et al. Advanced atherosclerotic foam cell formation has features of an acquired lysosomal storage disorder. , 2006, Rejuvenation research.
[36] J. Bertin,et al. Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. , 2006, Immunity.
[37] G. Bjørkøy,et al. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death , 2005, The Journal of cell biology.
[38] Jody C. Ullery,et al. Aggregated LDL and lipid dispersions induce lysosomal cholesteryl ester accumulation in macrophage foam cells Published, JLR Papers in Press, July 16, 2005. DOI 10.1194/jlr.M500059-JLR200 , 2005, Journal of Lipid Research.
[39] R. Pakala,et al. Rapamycin Attenuates Atherosclerotic Plaque Progression in Apolipoprotein E Knockout Mice: Inhibitory Effect on Monocyte Chemotaxis , 2005, Journal of cardiovascular pharmacology.
[40] Masaaki Komatsu,et al. Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice , 2005, The Journal of cell biology.
[41] J. Schneider,et al. "New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis. , 2005, Cell metabolism.
[42] Takeshi Tokuhisa,et al. The role of autophagy during the early neonatal starvation period , 2004, Nature.
[43] D. Schrijvers,et al. 7-Ketocholesterol Induces Protein Ubiquitination, Myelin Figure Formation, and Light Chain 3 Processing in Vascular Smooth Muscle Cells , 2004, Arteriosclerosis, thrombosis, and vascular biology.
[44] V. Dixit,et al. Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf , 2004, Nature.
[45] Govind Bhagat,et al. Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. , 2003, The Journal of clinical investigation.
[46] Arnold J. Levine,et al. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[47] Hong Yang,et al. Dietary restriction reduces atherosclerosis and oxidative stress in the aorta of apolipoprotein E-deficient mice , 2002, Mechanisms of Ageing and Development.
[48] G. Christ,et al. Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities. , 2001, The Journal of biological chemistry.
[49] P. Yancey,et al. Lysosomal cholesterol derived from mildly oxidized low density lipoprotein is resistant to efflux. , 2001, Journal of lipid research.
[50] S. Emr,et al. Autophagy as a regulated pathway of cellular degradation. , 2000, Science.
[51] J. Ju,et al. Skeletal muscle respiratory uncoupling prevents diet-induced obesity and insulin resistance in mice , 2000, Nature Medicine.
[52] U. Steinbrecher,et al. Cholesterol delivered to macrophages by oxidized low density lipoprotein is sequestered in lysosomes and fails to efflux normally. , 2000, Journal of lipid research.
[53] S. Hazen,et al. Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice. , 2000, The Journal of clinical investigation.
[54] R. Dean,et al. Cholesterol and oxysterol metabolism and subcellular distribution in macrophage foam cells. Accumulation of oxidized esters in lysosomes. , 2000, Journal of lipid research.
[55] G. D. De Meyer,et al. Cell composition, replication, and apoptosis in atherosclerotic plaques after 6 months of cholesterol withdrawal. , 1998, Circulation research.
[56] A. Daugherty,et al. Effects of heterozygous lipoprotein lipase deficiency on diet-induced atherosclerosis in mice. , 1998, Journal of lipid research.
[57] I. Ifrim,et al. Sequestration of acetylated LDL and cholesterol crystals by human monocyte-derived macrophages , 1995, The Journal of cell biology.
[58] R. Dean,et al. The intracellular storage and turnover of apolipoprotein B of oxidized LDL in macrophages. , 1992, Biochimica et biophysica acta.
[59] U. Steinbrecher,et al. Oxidized low density lipoprotein is resistant to cathepsins and accumulates within macrophages. , 1991, The Journal of biological chemistry.
[60] M. Whiting,et al. Cholesterol crystal formation and growth in model bile solutions. , 1983, Journal of lipid research.
[61] R. Gottlieb,et al. Autophagy in Atherosclerosis: A Cell Survival and Death Phenomenon With Therapeutic Potential , 2008 .
[62] F. Sánchez‐Madrid,et al. Rapamycin attenuates atherosclerosis induced by dietary cholesterol in apolipoprotein-deficient mice through a p27 Kip1 -independent pathway. , 2004, Atherosclerosis.
[63] E. Stadtman,et al. Oxidation of free amino acids and amino acid residues in proteins by radiolysis and by metal-catalyzed reactions. , 1993, Annual review of biochemistry.