LI-RADS Past, Present, and Future, From the AJR Special Series on Radiology Reporting and Data Systems.

The Liver Imaging and Reporting Data System (LI-RADS) is a comprehensive system for standardizing the terminology, interpretation, reporting, and data collection of liver imaging. Over the past 10 years, LI-RADS has undergone a substantial expansion in scope, building upon and refining its initial CT/MRI algorithm for HCC diagnosis and developing three new algorithms: Ultrasound (US) LI-RADS for HCC screening and surveillance, Contrast Enhanced US (CEUS) LI-RADS for HCC diagnosis, and LI-RADS CT/MRI Treatment Response. As of 2018, LI-RADS and the American Association for the Study of Liver Diseases (AASLD) share unified LR-5 criteria for the imaging-based diagnosis of HCC, and LI-RADS diagnostic criteria and management recommendations were integrated into the AALSD clinical practice guidance for HCC diagnosis, staging, and management. LI-RADS is updated in response to new knowledge, technology, and user feedback every 3-5 years. This article details the origins and growth of LI-RADS, reviews its current state, and articulates its short- and long-term objectives.