Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain
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A. Debnath | D. Cowburn | E. Freed | A. Cooper | A. Waheed | S. Bhattacharya | Xihui Zhang | F. Curreli | Hongtao Zhang
[1] Mark Yeager,et al. Atomic-level modelling of the HIV capsid , 2011 .
[2] R. Gijsbers,et al. Interplay between HIV Entry and Transportin-SR2 Dependency , 2011, Retrovirology.
[3] J. Nieman,et al. HIV Capsid is a Tractable Target for Small Molecule Therapeutic Intervention , 2010, PLoS pathogens.
[4] C. Aiken,et al. Small-Molecule Inhibition of Human Immunodeficiency Virus Type 1 Infection by Virus Capsid Destabilization , 2010, Journal of Virology.
[5] A. Engelman,et al. Flexible use of nuclear import pathways by HIV-1. , 2010, Cell host & microbe.
[6] E. Freed,et al. Novel approaches to inhibiting HIV-1 replication. , 2010, Antiviral research.
[7] Raymond E. Moellering,et al. Direct inhibition of the NOTCH transcription factor complex , 2010, Nature.
[8] Peijun Zhang,et al. Structural Convergence between Cryo-EM and NMR Reveals Intersubunit Interactions Critical for HIV-1 Capsid Function , 2009, Cell.
[9] A. Ansari,et al. Chemical biology: A Notch above other inhibitors , 2009, Nature.
[10] E. Freed,et al. Virus maturation as a new HIV-1 therapeutic target , 2009, Expert opinion on therapeutic targets.
[11] J. Briggs,et al. Structure and assembly of immature HIV , 2009, Proceedings of the National Academy of Sciences.
[12] Mark Yeager,et al. X-Ray Structures of the Hexameric Building Block of the HIV Capsid , 2009, Cell.
[13] Joe Lewis,et al. Residues in the HIV-1 Capsid Assembly Inhibitor Binding Site Are Essential for Maintaining the Assembly-competent Quaternary Structure of the Capsid Protein* , 2008, Journal of Biological Chemistry.
[14] L. Chaloin,et al. VSV-G pseudotyping rescues HIV-1 CA mutations that impair core assembly or stability , 2008, Retrovirology.
[15] Tam-Linh N Nguyen,et al. Cooperative role of the MHR and the CA dimerization helix in the maturation of the functional retrovirus capsid. , 2008, Virology.
[16] A. Debnath,et al. A cell-penetrating helical peptide as a potential HIV-1 inhibitor. , 2008, Journal of molecular biology.
[17] J. Flanagan,et al. Critical Role of Conserved Hydrophobic Residues within the Major Homology Region in Mature Retroviral Capsid Assembly , 2008, Journal of Virology.
[18] Mark Yeager,et al. The structural biology of HIV assembly. , 2008, Current opinion in structural biology.
[19] R. Shin,et al. Solution structure of a double mutant of the carboxy-terminal dimerization domain of the HIV-1 capsid protein. , 2008, Biochemistry.
[20] Anchi Cheng,et al. Structure of Full-Length HIV-1 CA: A Model for the Mature Capsid Lattice , 2007, Cell.
[21] S. Höglund,et al. Characterization of the invariable residue 51 mutations of human immunodeficiency virus type 1 capsid protein on in vitro CA assembly and infectivity , 2007, Retrovirology.
[22] I. Hewlett,et al. HIV-1 capsid protein and cyclophilin a as new targets for anti-AIDS therapeutic agents. , 2007, Infectious disorders drug targets.
[23] Yu-Fen Chang,et al. Mutations in capsid major homology region affect assembly and membrane affinity of HIV-1 Gag. , 2007, Journal of molecular biology.
[24] Steven Fletcher,et al. Protein-protein interaction inhibitors: small molecules from screening techniques. , 2007, Current topics in medicinal chemistry.
[25] Christopher L. Fillmore,et al. Electron cryotomography of immature HIV‐1 virions reveals the structure of the CA and SP1 Gag shells , 2007, The EMBO journal.
[26] S. Korsmeyer,et al. Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide. , 2007, Journal of the American Chemical Society.
[27] S. Höglund,et al. Mutation in the loop C-terminal to the cyclophilin A binding site of HIV-1 capsid protein disrupts proper virus assembly and infectivity , 2007, Retrovirology.
[28] G. Wagner,et al. Domain-swapped dimerization of the HIV-1 capsid C-terminal domain , 2007, Proceedings of the National Academy of Sciences.
[29] S. Korsmeyer,et al. A stapled BID BH3 helix directly binds and activates BAX. , 2006, Molecular cell.
[30] K. Nagashima,et al. Mutation of Dileucine-Like Motifs in the Human Immunodeficiency Virus Type 1 Capsid Disrupts Virus Assembly, Gag-Gag Interactions, Gag-Membrane Binding, and Virion Maturation , 2006, Journal of Virology.
[31] W. Liao,et al. A domain directly C-terminal to the major homology region of human immunodeficiency type 1 capsid protein plays a crucial role in directing both virus assembly and incorporation of Gag-Pol. , 2006, Virology.
[32] S. Fletcher,et al. Targeting protein–protein interactions by rational design: mimicry of protein surfaces , 2006, Journal of The Royal Society Interface.
[33] P. Watt,et al. Screening for peptide drugs from the natural repertoire of biodiverse protein folds , 2006, Nature Biotechnology.
[34] F. Förster,et al. The mechanism of HIV-1 core assembly: insights from three-dimensional reconstructions of authentic virions. , 2006, Structure.
[35] Marc C. Johnson,et al. The Retroviral Capsid Domain Dictates Virion Size, Morphology, and Coassembly of Gag into Virus-Like Particles , 2005, Journal of Virology.
[36] Hans-Georg Kräusslich,et al. The HIV-1 capsid protein C-terminal domain in complex with a virus assembly inhibitor , 2005, Nature Structural &Molecular Biology.
[37] V. Vogt. Blocking HIV-1 virus assembly , 2005, Nature Structural &Molecular Biology.
[38] Barbara Müller,et al. A peptide inhibitor of HIV-1 assembly in vitro , 2005, Nature Structural &Molecular Biology.
[39] A. Hamilton,et al. Strategies for targeting protein-protein interactions with synthetic agents. , 2005, Angewandte Chemie.
[40] E. Barklis,et al. Assembly of Human Immunodeficiency Virus Precursor Gag Proteins* , 2005, Journal of Biological Chemistry.
[41] A. Lazzarin. Enfuvirtide: the first HIV fusion inhibitor , 2005, Expert opinion on pharmacotherapy.
[42] E. Barklis,et al. Virus Particle Core Defects Caused by Mutations in the Human Immunodeficiency Virus Capsid N-Terminal Domain , 2005, Journal of Virology.
[43] C. Wild,et al. HIV-1 assembly and budding as targets for drug discovery. , 2005, Current opinion in investigational drugs.
[44] Mauricio G Mateu,et al. Electrostatic repulsion, compensatory mutations, and long-range non-additive effects at the dimerization interface of the HIV capsid protein. , 2005, Journal of molecular biology.
[45] A. Debnath,et al. N-Substituted Pyrrole Derivatives as Novel Human Immunodeficiency Virus Type 1 Entry Inhibitors That Interfere with the gp41 Six-Helix Bundle Formation and Block Virus Fusion , 2004, Antimicrobial Agents and Chemotherapy.
[46] S. Höglund,et al. Selected amino acid substitutions in the C-terminal region of human immunodeficiency virus type 1 capsid protein affect virus assembly and release. , 2004, The Journal of general virology.
[47] M. Wainberg,et al. In Vitro Identification and Characterization of an Early Complex Linking HIV-1 Genomic RNA Recognition and Pr55Gag Multimerization* , 2004, Journal of Biological Chemistry.
[48] S. Korsmeyer,et al. Activation of Apoptosis in Vivo by a Hydrocarbon-Stapled BH3 Helix , 2004, Science.
[49] Jason Lanman,et al. Investigation of N-terminal domain charged residues on the assembly and stability of HIV-1 CA. , 2004, Biochemistry.
[50] M. G. Mateu,et al. The dimerization domain of the HIV‐1 capsid protein binds a capsid protein‐derived peptide: A biophysical characterization , 2004, Protein science : a publication of the Protein Society.
[51] Michelle R. Arkin,et al. Small-molecule inhibitors of protein–protein interactions: progressing towards the dream , 2004, Nature Reviews Drug Discovery.
[52] Wesley I. Sundquist,et al. Assembly Properties of the Human Immunodeficiency Virus Type 1 CA Protein , 2004, Journal of Virology.
[53] I. Jones,et al. The molecular basis of HIV capsid assembly—five years of progress , 2004, Reviews in medical virology.
[54] E. Freed,et al. Late Domain-Dependent Inhibition of Equine Infectious Anemia Virus Budding , 2004, Journal of Virology.
[55] A. Cooper,et al. Energetics of cyclodextrin-induced dissociation of insulin , 1996, European Biophysics Journal.
[56] J. Cervia,et al. Enfuvirtide (T-20): a novel human immunodeficiency virus type 1 fusion inhibitor. , 2003, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[57] M. G. Mateu,et al. Thermodynamic Dissection of a Low Affinity Protein-Protein Interface Involved in Human Immunodeficiency Virus Assembly* , 2003, Journal of Biological Chemistry.
[58] Wesley I. Sundquist,et al. Functional Surfaces of the Human Immunodeficiency Virus Type 1 Capsid Protein , 2003, Journal of Virology.
[59] Eric Barklis,et al. Antiviral inhibition of the HIV-1 capsid protein. , 2003, Journal of molecular biology.
[60] J. Briggs,et al. Structural organization of authentic, mature HIV‐1 virions and cores , 2003, The EMBO journal.
[61] M. Shultz,et al. Interfacial peptide inhibitors of HIV-1 integrase activity and dimerization. , 2003, Bioorganic & medicinal chemistry letters.
[62] Michelle R. Arkin,et al. Binding of small molecules to an adaptive protein–protein interface , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[63] Wesley I. Sundquist,et al. Formation of a Human Immunodeficiency Virus Type 1 Core of Optimal Stability Is Crucial for Viral Replication , 2002, Journal of Virology.
[64] J. Kappes,et al. Emergence of Resistant Human Immunodeficiency Virus Type 1 in Patients Receiving Fusion Inhibitor (T-20) Monotherapy , 2002, Antimicrobial Agents and Chemotherapy.
[65] M. G. Mateu. Conformational stability of dimeric and monomeric forms of the C-terminal domain of human immunodeficiency virus-1 capsid protein. , 2002, Journal of molecular biology.
[66] M. Blackledge,et al. Solution structure and dynamics of Crh, the Bacillus subtilis catabolite repression HPr. , 2002, Journal of molecular biology.
[67] A. Patnaik,et al. Budding of Equine Infectious Anemia Virus Is Insensitive to Proteasome Inhibitors , 2002, Journal of Virology.
[68] Shibo Jiang,et al. Design of a protein surface antagonist based on alpha-helix mimicry: inhibition of gp41 assembly and viral fusion. , 2002, Angewandte Chemie.
[69] J. Mouscadet,et al. Peptide inhibitors of HIV-1 integrase dissociate the enzyme oligomers. , 2001, Biochemistry.
[70] S. Scarlata,et al. HIV-1 capsid protein forms spherical (immature-like) and tubular (mature-like) particles in vitro: structure switching by pH-induced conformational changes. , 2001, Biophysical journal.
[71] S. Scarlata,et al. Role of the major homology region in assembly of HIV-1 Gag. , 2001, Biochemistry.
[72] Wesley I. Sundquist,et al. Image reconstructions of helical assemblies of the HIV-1 CA protein , 2022 .
[73] A. Hamilton,et al. Peptide and protein recognition by designed molecules. , 2000, Chemical reviews.
[74] G. Verdine,et al. An All-Hydrocarbon Cross-Linking System for Enhancing the Helicity and Metabolic Stability of Peptides , 2000 .
[75] W. Sundquist,et al. Assembly and analysis of conical models for the HIV-1 core. , 1999, Science.
[76] L. Hanna. T-20: first of a new class of anti-HIV drugs. , 1999, BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation.
[77] W. Sundquist,et al. Biological Crystallography Structures of the Hiv-1 Capsid Protein Dimerization Domain at 2.6 a Ê Resolution , 2022 .
[78] B. Chesebro,et al. Effects of CCR5 and CD4 Cell Surface Concentrations on Infections by Macrophagetropic Isolates of Human Immunodeficiency Virus Type 1 , 1998, Journal of Virology.
[79] W. Sundquist,et al. Structure of the carboxyl-terminal dimerization domain of the HIV-1 capsid protein. , 1997, Science.
[80] H. Kräusslich,et al. In vitro assembly properties of purified bacterially expressed capsid proteins of human immunodeficiency virus. , 1997, European journal of biochemistry.
[81] James Js. T-20: entirely new antiretroviral. , 1997 .
[82] R. Kettmann,et al. The major homology region of bovine leukaemia virus p24gag is required for virus infectivity in vivo. , 1997, The Journal of general virology.
[83] A. Cooper,et al. Thermodynamics and kinetics of dissociation of ligand-induced dimers of vancomycin antibiotics , 1997 .
[84] J. James. T-20: entirely new antiretroviral. , 1997, AIDS treatment news.
[85] W. Sundquist,et al. Crystal Structure of Human Cyclophilin A Bound to the Amino-Terminal Domain of HIV-1 Capsid , 1996, Cell.
[86] F. Gage,et al. Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[87] I. Kuntz,et al. Engineering human immunodeficiency virus 1 protease heterodimers as macromolecular inhibitors of viral maturation. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[88] Carol Carter,et al. Crystal structure of dimeric HIV-1 capsid protein , 1996, Nature Structural Biology.
[89] R S Goody,et al. Interface Peptides as Structure-based Human Immunodeficiency Virus Reverse Transcriptase Inhibitors (*) , 1995, The Journal of Biological Chemistry.
[90] E. Freed,et al. p6Gag is required for particle production from full-length human immunodeficiency virus type 1 molecular clones expressing protease , 1995, Journal of virology.
[91] J. Wills,et al. Genetic analysis of the major homology region of the Rous sarcoma virus Gag protein , 1995, Journal of virology.
[92] E. Freed,et al. Virion incorporation of envelope glycoproteins with long but not short cytoplasmic tails is blocked by specific, single amino acid substitutions in the human immunodeficiency virus type 1 matrix , 1995, Journal of virology.
[93] A. Gronenborn,et al. Three‐dimensional structures of α and β chemokines , 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[94] S. Höglund,et al. Role of the major homology region of human immunodeficiency virus type 1 in virion morphogenesis , 1994, Journal of virology.
[95] E. Freed,et al. Evidence for a functional interaction between the V1/V2 and C4 domains of human immunodeficiency virus type 1 envelope glycoprotein gp120 , 1994, Journal of virology.
[96] J. Burns,et al. Generation of high-titer pseudotyped retroviral vectors with very broad host range. , 1994, Methods in cell biology.
[97] Jeremy Luban,et al. Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B , 1993, Cell.
[98] C. Strambio-De-Castillia,et al. Mutational analysis of the major homology region of Mason-Pfizer monkey virus by use of saturation mutagenesis , 1992, Journal of virology.
[99] S. Jiang,et al. Enhancement of human immunodeficiency virus type 1 infection by antisera to peptides from the envelope glycoproteins gp120/gp41 [published erratum appears in J Exp Med 1992 Feb 1;175(2):621] , 1991, The Journal of experimental medicine.
[100] H. Gendelman,et al. Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone , 1986, Journal of virology.