Meta-GWAS identifies the heritability of acute radiation-induced toxicities in head and neck cancer.

[1]  A. Dunning,et al.  A genome-wide association study of radiotherapy induced toxicity in head and neck cancer patients identifies a susceptibility locus associated with mucositis , 2022, British Journal of Cancer.

[2]  H. Boezen,et al.  A two-stage genome-wide association study of radiation-induced acute toxicity in head and neck cancer , 2021, Journal of translational medicine.

[3]  Ilja M. Nolte,et al.  GWASinspector: comprehensive quality control of genome-wide association study results , 2021, Bioinform..

[4]  S. Bölte,et al.  The influence of common polygenic risk and gene sets on social skills group training response in autism spectrum disorder , 2020, npj Genomic Medicine.

[5]  W. Xue,et al.  Genome-wide association study identifies genetic susceptibility loci and pathways of radiation-induced acute oral mucositis , 2020, Journal of Translational Medicine.

[6]  Xueqi Fu,et al.  Proapoptotic Mitochondrial Carrier Homolog Protein PSAP Mediates Death Receptor 6 Induced Apoptosis. , 2020, Journal of Alzheimer's disease : JAD.

[7]  S. Bölte,et al.  The influence of common polygenic risk and gene sets on social skills group training response in autism spectrum disorder , 2019, npj Genomic Medicine.

[8]  A. McKnight,et al.  Genetic Susceptibility to Chronic Kidney Disease – Some More Pieces for the Heritability Puzzle , 2019, Front. Genet..

[9]  John P. Rice,et al.  Identification of common genetic risk variants for autism spectrum disorder , 2019, Nature Genetics.

[10]  D. de Ruysscher,et al.  Radiotherapy toxicity , 2019, Nature Reviews Disease Primers.

[11]  Radiotherapy toxicity , 2019, Nature Reviews Disease Primers.

[12]  Jakob Grove,et al.  Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection , 2018, Nature Genetics.

[13]  Anders M. Dale,et al.  Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function , 2017, JAMA psychiatry.

[14]  Jian Yang,et al.  Concepts, estimation and interpretation of SNP-based heritability , 2017, Nature Genetics.

[15]  Petra Seibold,et al.  Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients. , 2016, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[16]  Johannes A Langendijk,et al.  The Quest for Evidence for Proton Therapy: Model-Based Approach and Precision Medicine. , 2016, International journal of radiation oncology, biology, physics.

[17]  M. Amiji,et al.  Mitochondrial biology, targets, and drug delivery. , 2015, Journal of controlled release : official journal of the Controlled Release Society.

[18]  M. Daly,et al.  An Atlas of Genetic Correlations across Human Diseases and Traits , 2015, Nature Genetics.

[19]  Honghao Zhou,et al.  Radiogenomics helps to achieve personalized therapy by evaluating patient responses to radiation treatment. , 2015, Carcinogenesis.

[20]  V. B. Manjunath,et al.  Polymorphisms in Radio-Responsive Genes and Its Association with Acute Toxicity among Head and Neck Cancer Patients , 2014, PloS one.

[21]  M. Daly,et al.  LD Score regression distinguishes confounding from polygenicity in genome-wide association studies , 2014, Nature Genetics.

[22]  Patrick F. Sullivan,et al.  Genetic architectures of psychiatric disorders: the emerging picture and its implications , 2012, Nature Reviews Genetics.

[23]  A. Dunning,et al.  Standardized Total Average Toxicity score: a scale- and grade-independent measure of late radiotherapy toxicity to facilitate pooling of data from different studies. , 2012, International journal of radiation oncology, biology, physics.

[24]  Stef van Buuren,et al.  MICE: Multivariate Imputation by Chained Equations in R , 2011 .

[25]  L. Livi,et al.  Association between single nucleotide polymorphisms in the XRCC1 and RAD51 genes and clinical radiosensitivity in head and neck cancer. , 2011, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[26]  Yun Li,et al.  METAL: fast and efficient meta-analysis of genomewide association scans , 2010, Bioinform..

[27]  Jason H. Moore,et al.  Missing heritability and strategies for finding the underlying causes of complex disease , 2010, Nature Reviews Genetics.

[28]  Christophe Badie,et al.  Evidence for significant heritability of apoptotic and cell cycle responses to ionising radiation , 2008, Human Genetics.

[29]  Manuel A. R. Ferreira,et al.  PLINK: a tool set for whole-genome association and population-based linkage analyses. , 2007, American journal of human genetics.

[30]  P. Donnelly,et al.  A new multipoint method for genome-wide association studies by imputation of genotypes , 2007, Nature Genetics.

[31]  R. Gatti The Inherited Basis of Human Radiosensitivity , 2001, Acta oncologica.

[32]  D. Evans,et al.  Heritability of cellular radiosensitivity: a marker of low-penetrance predisposition genes in breast cancer? , 1999, American journal of human genetics.

[33]  L. Berkman,et al.  Genetic susceptibility to death from coronary heart disease in a study of twins. , 1994, The New England journal of medicine.