Abstract 13098: Mechanically-Induced Premature Ventricular Excitation is Mediated by Cation Non-Selective Stretch-Activated Channels and Depends on the Extent of Local Tissue Deformation in Isolated Rabbit Heart

Introduction: Myocardial stretch can cause arrhythmia. The relative importance of local vs. global stimuli is unknown. We hypothesize that mechanically-induced premature ventricular excitation (PVE...